메뉴 건너뛰기




Volumn 11, Issue 4, 2007, Pages 707-725

The Role of the Woodchuck Model in the Treatment of Hepatitis B Virus Infection

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; CLEVUDINE; COMPLEMENTARY DNA; CYCLOSPORIN A; DOUBLE STRANDED DNA; ENTECAVIR; HEPATITIS B VACCINE; LAMIVUDINE; NUCLEOSIDE DERIVATIVE; PLACEBO; VIRUS DNA; VIRUS RNA;

EID: 35548960369     PISSN: 10893261     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cld.2007.08.012     Document Type: Review
Times cited : (14)

References (84)
  • 1
    • 35548997518 scopus 로고    scopus 로고
    • World Health Organization. Hepatitis B. World Health Organization Fact Sheet No. 204. Available at: http://who.int/mediacentre/factsheets/fs204/en. Accessed March 1, 2007.
  • 2
    • 1642410856 scopus 로고    scopus 로고
    • Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures
    • Levanchy D. Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures. J Viral Hepat 11 (2004) 97-107
    • (2004) J Viral Hepat , vol.11 , pp. 97-107
    • Levanchy, D.1
  • 3
    • 0346765512 scopus 로고    scopus 로고
    • Viral hepatitis B
    • Lai C.L., Ratziu V., Yuen M.F., et al. Viral hepatitis B. Lancet 362 (2003) 2089-2094
    • (2003) Lancet , vol.362 , pp. 2089-2094
    • Lai, C.L.1    Ratziu, V.2    Yuen, M.F.3
  • 4
    • 0035223703 scopus 로고    scopus 로고
    • The woodchuck model of hepatitis B virus infection
    • Tennant B.C., and Gerin J.L. The woodchuck model of hepatitis B virus infection. ILAR J 42 2 (2001) 89-102
    • (2001) ILAR J , vol.42 , Issue.2 , pp. 89-102
    • Tennant, B.C.1    Gerin, J.L.2
  • 5
    • 7044264687 scopus 로고    scopus 로고
    • Hepatocellular carcinoma in the woodchuck model of hepatitis B virus infection
    • Tennant B.C., Toshkov I.A., Peek S.F., et al. Hepatocellular carcinoma in the woodchuck model of hepatitis B virus infection. Gastroenterology 127 (2004) S283-S293
    • (2004) Gastroenterology , vol.127
    • Tennant, B.C.1    Toshkov, I.A.2    Peek, S.F.3
  • 6
    • 33846534236 scopus 로고    scopus 로고
    • The woodchuck as an animal model for pathogenesis and therapy of chronic hepatitis B virus infection
    • Menne S., and Cote P.J. The woodchuck as an animal model for pathogenesis and therapy of chronic hepatitis B virus infection. World J Gastroenterol 13 1 (2007) 104-124
    • (2007) World J Gastroenterol , vol.13 , Issue.1 , pp. 104-124
    • Menne, S.1    Cote, P.J.2
  • 7
    • 0032826033 scopus 로고    scopus 로고
    • Unraveling hepatitis B virus infection of mice and men (and woodchucks and ducks)
    • Menne S., and Tennant B.C. Unraveling hepatitis B virus infection of mice and men (and woodchucks and ducks). Nat Med 5 10 (1999) 1125-1126
    • (1999) Nat Med , vol.5 , Issue.10 , pp. 1125-1126
    • Menne, S.1    Tennant, B.C.2
  • 8
    • 0018084546 scopus 로고
    • A virus similar to human hepatitis B virus associated with hepatitis and hepatoma in woodchucks
    • Summers J., Smolec J.M., and Snyder R. A virus similar to human hepatitis B virus associated with hepatitis and hepatoma in woodchucks. Proc Natl Acad Sci USA 75 (1978) 4533-4537
    • (1978) Proc Natl Acad Sci USA , vol.75 , pp. 4533-4537
    • Summers, J.1    Smolec, J.M.2    Snyder, R.3
  • 9
    • 0019557510 scopus 로고
    • Woodchuck hepatitis virus in natural woodchuck populations
    • Tyler G.V., Summers J.W., and Snyder R.L. Woodchuck hepatitis virus in natural woodchuck populations. J Wildl Dis 17 2 (1981) 297-301
    • (1981) J Wildl Dis , vol.17 , Issue.2 , pp. 297-301
    • Tyler, G.V.1    Summers, J.W.2    Snyder, R.L.3
  • 10
    • 0020086522 scopus 로고
    • Nucleotide sequence of a cloned woodchuck hepatitis virus sequence
    • Galibert F., Chen T.N., and Mandart E. Nucleotide sequence of a cloned woodchuck hepatitis virus sequence. J Virol 41 (1982) 51-65
    • (1982) J Virol , vol.41 , pp. 51-65
    • Galibert, F.1    Chen, T.N.2    Mandart, E.3
  • 11
    • 0019212914 scopus 로고
    • A virus in Beechey ground squirrels that is related to hepatitis B virus in humans
    • Marion P.L., Oshiro L.S., Regnery D.C., et al. A virus in Beechey ground squirrels that is related to hepatitis B virus in humans. Proc Natl Acad Sci USA 77 5 (1980) 2941-2945
    • (1980) Proc Natl Acad Sci USA , vol.77 , Issue.5 , pp. 2941-2945
    • Marion, P.L.1    Oshiro, L.S.2    Regnery, D.C.3
  • 12
    • 0038043101 scopus 로고
    • Hepatocellular carcinoma in ground squirrels persistently infected with ground squirrel hepatitis virus
    • Marion P.L., Van Davelaar M.J., Knight S.S., et al. Hepatocellular carcinoma in ground squirrels persistently infected with ground squirrel hepatitis virus. Proc Natl Acad Sci USA 83 12 (1986) 4543-4546
    • (1986) Proc Natl Acad Sci USA , vol.83 , Issue.12 , pp. 4543-4546
    • Marion, P.L.1    Van Davelaar, M.J.2    Knight, S.S.3
  • 13
    • 33846555276 scopus 로고    scopus 로고
    • Avian hepatitis B viruses: molecular and cellular biology, phylogenesis, and host tropism
    • Funk A., Mhamdi M., Will H., et al. Avian hepatitis B viruses: molecular and cellular biology, phylogenesis, and host tropism. World J Gastroenterol 13 1 (2007) 91-103
    • (2007) World J Gastroenterol , vol.13 , Issue.1 , pp. 91-103
    • Funk, A.1    Mhamdi, M.2    Will, H.3
  • 14
    • 0030707941 scopus 로고    scopus 로고
    • Hepatitis B virus infection
    • Lee W. Hepatitis B virus infection. N Engl J Med 337 (1997) 1733-1745
    • (1997) N Engl J Med , vol.337 , pp. 1733-1745
    • Lee, W.1
  • 15
    • 0022000510 scopus 로고
    • Acute hepatitis B virus infection: relation of age to the clinical expression of disease and subsequent development of the carrier state
    • McMahon B.J., Alward W.L.M., Hall D.B., et al. Acute hepatitis B virus infection: relation of age to the clinical expression of disease and subsequent development of the carrier state. J Infect Dis 151 (1985) 599-603
    • (1985) J Infect Dis , vol.151 , pp. 599-603
    • McMahon, B.J.1    Alward, W.L.M.2    Hall, D.B.3
  • 16
    • 33746339209 scopus 로고    scopus 로고
    • A treatment algorithm for the management of chronic hepatitis B virus infection in the United States: an update
    • Keeffe E.B., Dieterich D.T., Han S.B., et al. A treatment algorithm for the management of chronic hepatitis B virus infection in the United States: an update. Clin Gastroenterol Hepatol 4 8 (2006) 936-961
    • (2006) Clin Gastroenterol Hepatol , vol.4 , Issue.8 , pp. 936-961
    • Keeffe, E.B.1    Dieterich, D.T.2    Han, S.B.3
  • 17
    • 0023630942 scopus 로고
    • Hepatitis B virus deoxyribonucleic acid in liver of chronic carriers: correlation with serum markers and changes associated with loss of hepatitis B e antigen after antiviral therapy
    • Di Bisceglie A.M., Waggoner J.G., and Hoofnagle J.H. Hepatitis B virus deoxyribonucleic acid in liver of chronic carriers: correlation with serum markers and changes associated with loss of hepatitis B e antigen after antiviral therapy. Gastroenterology 93 (1987) 1236-1241
    • (1987) Gastroenterology , vol.93 , pp. 1236-1241
    • Di Bisceglie, A.M.1    Waggoner, J.G.2    Hoofnagle, J.H.3
  • 18
    • 33847701354 scopus 로고    scopus 로고
    • AASLD practice guidelines: chronic hepatitis B
    • Lok A.S.F., and McMahon B.J. AASLD practice guidelines: chronic hepatitis B. Hepatology 45 2 (2007) 507-539
    • (2007) Hepatology , vol.45 , Issue.2 , pp. 507-539
    • Lok, A.S.F.1    McMahon, B.J.2
  • 19
    • 0035142201 scopus 로고    scopus 로고
    • Animal models of hepadnavirus-associated hepatocellular carcinoma
    • Tennant B.C. Animal models of hepadnavirus-associated hepatocellular carcinoma. Clin Liver Dis 5 (2001) 43-68
    • (2001) Clin Liver Dis , vol.5 , pp. 43-68
    • Tennant, B.C.1
  • 20
    • 0344607783 scopus 로고
    • Hepatocarcinogenicity of the woodchuck hepatitis virus
    • Popper H., Roth L., Purcell R.H., et al. Hepatocarcinogenicity of the woodchuck hepatitis virus. Proc Natl Acad Sci USA 84 (1987) 866-870
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 866-870
    • Popper, H.1    Roth, L.2    Purcell, R.H.3
  • 21
    • 0023219186 scopus 로고
    • Relation of the hepatitis B virus carrier state to hepatocellular carcinoma
    • Popper H., Shafritz D.A., and Hoofnagle J.H. Relation of the hepatitis B virus carrier state to hepatocellular carcinoma. Hepatology 7 4 (1987) 764-772
    • (1987) Hepatology , vol.7 , Issue.4 , pp. 764-772
    • Popper, H.1    Shafritz, D.A.2    Hoofnagle, J.H.3
  • 22
    • 84984555343 scopus 로고    scopus 로고
    • Hepatitis B e antigen and the risk of hepatocellular carcinoma
    • Yang H.I., Lu S.N., Liaw Y.F., et al. Hepatitis B e antigen and the risk of hepatocellular carcinoma. N Engl J Med 347 (2002) 168-174
    • (2002) N Engl J Med , vol.347 , pp. 168-174
    • Yang, H.I.1    Lu, S.N.2    Liaw, Y.F.3
  • 23
    • 29944436855 scopus 로고    scopus 로고
    • Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level
    • Chen C.J., Yang H.I., Su J., et al. Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level. JAMA 296 (2006) 65-73
    • (2006) JAMA , vol.296 , pp. 65-73
    • Chen, C.J.1    Yang, H.I.2    Su, J.3
  • 24
    • 33846473749 scopus 로고    scopus 로고
    • Hepatitis B virus-induced oncogenesis
    • Lupberger J., and Hildt E. Hepatitis B virus-induced oncogenesis. World J Gastroenterol 13 1 (2007) 74-81
    • (2007) World J Gastroenterol , vol.13 , Issue.1 , pp. 74-81
    • Lupberger, J.1    Hildt, E.2
  • 25
    • 0022641627 scopus 로고
    • Stable integration of woodchuck hepatitis virus DNA in transplanted tumors and established tissue culture cells derived from a woodchuck primary hepatocellular carcinoma
    • Kaneko S., Oshima T., Kodama K., et al. Stable integration of woodchuck hepatitis virus DNA in transplanted tumors and established tissue culture cells derived from a woodchuck primary hepatocellular carcinoma. Cancer Res 46 (1986) 3608-3613
    • (1986) Cancer Res , vol.46 , pp. 3608-3613
    • Kaneko, S.1    Oshima, T.2    Kodama, K.3
  • 26
    • 0024571542 scopus 로고
    • Hepatocellular carcinoma in woodchuck hepatitis virus-infected woodchucks: presence of viral DNA in tumor tissue from chronic carriers and animals serologically recovered from acute infections
    • Korba B.E., Wells F.V., Baldwin B., et al. Hepatocellular carcinoma in woodchuck hepatitis virus-infected woodchucks: presence of viral DNA in tumor tissue from chronic carriers and animals serologically recovered from acute infections. Hepatology 9 3 (1989) 461-470
    • (1989) Hepatology , vol.9 , Issue.3 , pp. 461-470
    • Korba, B.E.1    Wells, F.V.2    Baldwin, B.3
  • 27
    • 0024323310 scopus 로고
    • Characterization of woodchuck hepatitis virus DNA and mRNA in the hepatocellular carcinomas of woodchucks
    • Fuchs K., Heberger C., Weimer T., et al. Characterization of woodchuck hepatitis virus DNA and mRNA in the hepatocellular carcinomas of woodchucks. Hepatology 10 2 (1989) 215-220
    • (1989) Hepatology , vol.10 , Issue.2 , pp. 215-220
    • Fuchs, K.1    Heberger, C.2    Weimer, T.3
  • 28
    • 0035899344 scopus 로고    scopus 로고
    • A DNA microarray screen for genes involved in c-MYC and N-MYC oncogenesis in human tumors
    • Schildiner O., and Benvenisty N. A DNA microarray screen for genes involved in c-MYC and N-MYC oncogenesis in human tumors. Oncogene 20 36 (2001) 4984-4994
    • (2001) Oncogene , vol.20 , Issue.36 , pp. 4984-4994
    • Schildiner, O.1    Benvenisty, N.2
  • 29
    • 0026793219 scopus 로고
    • Hepadnavirus integration: mechanisms of activation of the N-myc2 retrotransposon in woodchuck liver tumors
    • Wei Y., Fourel G., Ponzetto A., et al. Hepadnavirus integration: mechanisms of activation of the N-myc2 retrotransposon in woodchuck liver tumors. J Virol 66 9 (1992) 5265-5276
    • (1992) J Virol , vol.66 , Issue.9 , pp. 5265-5276
    • Wei, Y.1    Fourel, G.2    Ponzetto, A.3
  • 30
    • 0025167175 scopus 로고
    • Frequent activation of N-myc genes by hepadnavirus insertion in woodchuck liver tumors
    • Fourel G., Trepo C., Bougueleret L., et al. Frequent activation of N-myc genes by hepadnavirus insertion in woodchuck liver tumors. Nature 347 (1990) 294-298
    • (1990) Nature , vol.347 , pp. 294-298
    • Fourel, G.1    Trepo, C.2    Bougueleret, L.3
  • 31
    • 0031780718 scopus 로고    scopus 로고
    • Woodchuck hepatitis virus enhancer I and enhancer II are both involved in N-myc2 activation in woodchuck liver tumors
    • Flajolet M., Tiollais P., Buendia M.-A., et al. Woodchuck hepatitis virus enhancer I and enhancer II are both involved in N-myc2 activation in woodchuck liver tumors. J Virol 72 7 (1998) 6175-6180
    • (1998) J Virol , vol.72 , Issue.7 , pp. 6175-6180
    • Flajolet, M.1    Tiollais, P.2    Buendia, M.-A.3
  • 32
    • 0034682340 scopus 로고    scopus 로고
    • Hepatocellular carcinoma in WHV/N-myc2 transgenic mice: oncogenic mutations of beta-catenin and synergistic effect of p53 null alleles
    • Renard C.A., Fourel G., Bralet M.P., et al. Hepatocellular carcinoma in WHV/N-myc2 transgenic mice: oncogenic mutations of beta-catenin and synergistic effect of p53 null alleles. Oncogene 19 22 (2000) 2678-2686
    • (2000) Oncogene , vol.19 , Issue.22 , pp. 2678-2686
    • Renard, C.A.1    Fourel, G.2    Bralet, M.P.3
  • 33
    • 0026517303 scopus 로고
    • Frequent amplification of c-myc in ground squirrel liver tumors associated with past or ongoing infection with a hepadnavirus
    • Transy C., Fourel G., Robinson W.S., et al. Frequent amplification of c-myc in ground squirrel liver tumors associated with past or ongoing infection with a hepadnavirus. Proc Natl Acad Sci USA 89 9 (1992) 3874-3878
    • (1992) Proc Natl Acad Sci USA , vol.89 , Issue.9 , pp. 3874-3878
    • Transy, C.1    Fourel, G.2    Robinson, W.S.3
  • 34
    • 0025966721 scopus 로고
    • Wooodchuck hepatitis virus is a more efficient oncogenic agent than ground squirrel hepatitis virus in a common host
    • Seeger C., Baldwin B., Hornbuckle W.E., et al. Wooodchuck hepatitis virus is a more efficient oncogenic agent than ground squirrel hepatitis virus in a common host. J Virol 65 4 (1991) 1673-1679
    • (1991) J Virol , vol.65 , Issue.4 , pp. 1673-1679
    • Seeger, C.1    Baldwin, B.2    Hornbuckle, W.E.3
  • 35
    • 1842480063 scopus 로고    scopus 로고
    • Integration of woodchuck hepatitis and N-myc rearrangement determine size and histologic grade of hepatic tumors
    • Jacob J.R., Sterczer A., Toshkov I.A., et al. Integration of woodchuck hepatitis and N-myc rearrangement determine size and histologic grade of hepatic tumors. Hepatology 39 (2004) 1008-1016
    • (2004) Hepatology , vol.39 , pp. 1008-1016
    • Jacob, J.R.1    Sterczer, A.2    Toshkov, I.A.3
  • 36
    • 0027205094 scopus 로고
    • Coordinate expression of N-myc2 and insulin-like growth factor II in precancerous altered hepatic foci in woodchuck hepatitis virus carriers
    • Yang D., Alt E., and Rogler C.E. Coordinate expression of N-myc2 and insulin-like growth factor II in precancerous altered hepatic foci in woodchuck hepatitis virus carriers. Cancer Res 53 9 (1993) 2020-2027
    • (1993) Cancer Res , vol.53 , Issue.9 , pp. 2020-2027
    • Yang, D.1    Alt, E.2    Rogler, C.E.3
  • 37
    • 0030660181 scopus 로고    scopus 로고
    • Human hepatic preneoplasia: phenotypes and proliferation kinetics of foci and nodules of altered hepatocytes and their relationship to liver cell dysplasia
    • Su Q., Benner A., Hofmann W.J., et al. Human hepatic preneoplasia: phenotypes and proliferation kinetics of foci and nodules of altered hepatocytes and their relationship to liver cell dysplasia. Virchows Arch 431 (1997) 391-406
    • (1997) Virchows Arch , vol.431 , pp. 391-406
    • Su, Q.1    Benner, A.2    Hofmann, W.J.3
  • 38
    • 0037261429 scopus 로고    scopus 로고
    • Relevance of hepatic preneoplasia for human hepatocarcinogenesis
    • Su Q., and Bannasch P. Relevance of hepatic preneoplasia for human hepatocarcinogenesis. Toxicol Pathol 31 1 (2003) 126-133
    • (2003) Toxicol Pathol , vol.31 , Issue.1 , pp. 126-133
    • Su, Q.1    Bannasch, P.2
  • 39
    • 0037255302 scopus 로고    scopus 로고
    • Significance of hepatic preneoplasia in risk identification and early detection of neoplasia
    • Bannasch P., Haertel T., and Su Q. Significance of hepatic preneoplasia in risk identification and early detection of neoplasia. Toxicol Pathol 31 1 (2003) 134-139
    • (2003) Toxicol Pathol , vol.31 , Issue.1 , pp. 134-139
    • Bannasch, P.1    Haertel, T.2    Su, Q.3
  • 40
    • 0019791877 scopus 로고
    • Integration of hepatitis B virus DNA into the genome of liver cells in chronic liver disease and hepatocellular carcinoma. Studies in percutaneous liver biopsy and post-mortem tissue specimens
    • Shafritz D.A., Shouval D., Sherman H.I., et al. Integration of hepatitis B virus DNA into the genome of liver cells in chronic liver disease and hepatocellular carcinoma. Studies in percutaneous liver biopsy and post-mortem tissue specimens. N Engl J Med 305 18 (1981) 1067-1073
    • (1981) N Engl J Med , vol.305 , Issue.18 , pp. 1067-1073
    • Shafritz, D.A.1    Shouval, D.2    Sherman, H.I.3
  • 41
    • 22644435919 scopus 로고    scopus 로고
    • Large scaled analysis of hepatitis B virus (HBV) DNA integration in HBV related hepatocellular carcinomas
    • Murakami Y., Saigo K., Takashima H., et al. Large scaled analysis of hepatitis B virus (HBV) DNA integration in HBV related hepatocellular carcinomas. Gut 54 8 (2005) 1162-1168
    • (2005) Gut , vol.54 , Issue.8 , pp. 1162-1168
    • Murakami, Y.1    Saigo, K.2    Takashima, H.3
  • 42
    • 0023520212 scopus 로고
    • Chromosomal translocation and inverted duplication associated with integrated hepatitis B virus in hepatocellular carcinomas
    • Tokino T., Fukushige S., Nakamura T., et al. Chromosomal translocation and inverted duplication associated with integrated hepatitis B virus in hepatocellular carcinomas. J Virol 61 (1987) 3848-3854
    • (1987) J Virol , vol.61 , pp. 3848-3854
    • Tokino, T.1    Fukushige, S.2    Nakamura, T.3
  • 43
    • 0037871858 scopus 로고    scopus 로고
    • Integration of hepatitis B virus (HBV) and human papillomavirus (HPV) into the human telomerase reverse transcriptase gene in lever and cervical cancers
    • Ferber M.J., Montoya D.P., Yu C., et al. Integration of hepatitis B virus (HBV) and human papillomavirus (HPV) into the human telomerase reverse transcriptase gene in lever and cervical cancers. Oncogene 22 (2003) 3813-3820
    • (2003) Oncogene , vol.22 , pp. 3813-3820
    • Ferber, M.J.1    Montoya, D.P.2    Yu, C.3
  • 44
    • 0033860678 scopus 로고    scopus 로고
    • Molecular bases for the development of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC)
    • Brechot C., Gozuacik D., Murakami T., et al. Molecular bases for the development of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). Semin Cancer Biol 10 (2000) 211-231
    • (2000) Semin Cancer Biol , vol.10 , pp. 211-231
    • Brechot, C.1    Gozuacik, D.2    Murakami, T.3
  • 45
    • 30844455365 scopus 로고    scopus 로고
    • Lack of WHV integration nearby N-myc2 and in the downstream, b3n and win loci in a considerable fraction of liver tumors with activated N-myc2 from naturally infected wild woodchucks
    • Bruni R., Conti I., Villano U., et al. Lack of WHV integration nearby N-myc2 and in the downstream, b3n and win loci in a considerable fraction of liver tumors with activated N-myc2 from naturally infected wild woodchucks. Virology 345 1 (2006) 258-269
    • (2006) Virology , vol.345 , Issue.1 , pp. 258-269
    • Bruni, R.1    Conti, I.2    Villano, U.3
  • 46
    • 0036949499 scopus 로고    scopus 로고
    • Hepatitis B virus mutants: an overview
    • Chen W.N., and Oon C.J. Hepatitis B virus mutants: an overview. J Gastroenterol Hepatol 17 (2002) S497-S499
    • (2002) J Gastroenterol Hepatol , vol.17
    • Chen, W.N.1    Oon, C.J.2
  • 47
    • 0034011592 scopus 로고    scopus 로고
    • Treatment of chronic woodchuck hepatitis virus infection in the Eastern woodchuck (Marmota monax) with nucleoside analogues is predictive of therapy for chronic hepatitis B virus infection in humans
    • Korba B.E., Cote P., Hornbuckle W., et al. Treatment of chronic woodchuck hepatitis virus infection in the Eastern woodchuck (Marmota monax) with nucleoside analogues is predictive of therapy for chronic hepatitis B virus infection in humans. Hepatology 31 5 (2000) 1165-1175
    • (2000) Hepatology , vol.31 , Issue.5 , pp. 1165-1175
    • Korba, B.E.1    Cote, P.2    Hornbuckle, W.3
  • 48
    • 0031782844 scopus 로고    scopus 로고
    • Pharmacodynamics of (-)-beta-2′,3′-dideoxy-3′-thiacytidine in chronically virus-infected woodchucks compared to its pharmacodynamics in humans
    • Hurwitz S.J., Tennant B.C., Korba B.E., et al. Pharmacodynamics of (-)-beta-2′,3′-dideoxy-3′-thiacytidine in chronically virus-infected woodchucks compared to its pharmacodynamics in humans. Antimicrob Agents Chemother 42 11 (1998) 2804-2809
    • (1998) Antimicrob Agents Chemother , vol.42 , Issue.11 , pp. 2804-2809
    • Hurwitz, S.J.1    Tennant, B.C.2    Korba, B.E.3
  • 49
    • 2342631429 scopus 로고    scopus 로고
    • Viral pharmacodynamic model for beta-2′,3′-dideoxy-3′-5-fluoro-3′-thiacytidine (emtricitabine) in chronically infected woodchucks
    • Hurwitz S.J., Tennant B.C., Korba B.E., et al. Viral pharmacodynamic model for beta-2′,3′-dideoxy-3′-5-fluoro-3′-thiacytidine (emtricitabine) in chronically infected woodchucks. Antivir Chem Chemother 13 (2002) 165-176
    • (2002) Antivir Chem Chemother , vol.13 , pp. 165-176
    • Hurwitz, S.J.1    Tennant, B.C.2    Korba, B.E.3
  • 50
    • 21444441074 scopus 로고    scopus 로고
    • Antiviral effect of oral administration of tenofovir disoproxil fumarate in woodchucks with chronic woodchuck hepatitis virus infection
    • Menne S., Cote P.J., Korba B.E., et al. Antiviral effect of oral administration of tenofovir disoproxil fumarate in woodchucks with chronic woodchuck hepatitis virus infection. Antimicrob Agents Chemother 49 7 (2005) 2720-2728
    • (2005) Antimicrob Agents Chemother , vol.49 , Issue.7 , pp. 2720-2728
    • Menne, S.1    Cote, P.J.2    Korba, B.E.3
  • 51
    • 0033955317 scopus 로고    scopus 로고
    • Enhanced antiviral benefit of combination therapy with lamivudine and famciclovir against WHV replication in chronic WHV carrier woodchucks
    • Korba B.E., Cote P., Hornbuckle W., et al. Enhanced antiviral benefit of combination therapy with lamivudine and famciclovir against WHV replication in chronic WHV carrier woodchucks. Antiviral Res 45 1 (2000) 19-32
    • (2000) Antiviral Res , vol.45 , Issue.1 , pp. 19-32
    • Korba, B.E.1    Cote, P.2    Hornbuckle, W.3
  • 52
    • 0034806770 scopus 로고    scopus 로고
    • Antiviral efficacy and pharmacokinetics of oral adefovir dipivoxil in chronically woodchuck hepatitis virus-infected woodchucks
    • Cullen J.M., Li D.H., Brown C., et al. Antiviral efficacy and pharmacokinetics of oral adefovir dipivoxil in chronically woodchuck hepatitis virus-infected woodchucks. Antimicrob Agents Chemother 45 (2001) 2740-2745
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 2740-2745
    • Cullen, J.M.1    Li, D.H.2    Brown, C.3
  • 53
    • 0034808628 scopus 로고    scopus 로고
    • Antiviral beta-L-nucleosides specific for hepatitis B virus infection
    • Standring D.N., Bridges E.G., Placidi L., et al. Antiviral beta-L-nucleosides specific for hepatitis B virus infection. Antivir Chem Chemother 12 S1 (2001) 119-129
    • (2001) Antivir Chem Chemother , vol.12 , Issue.SUPPL.1 , pp. 119-129
    • Standring, D.N.1    Bridges, E.G.2    Placidi, L.3
  • 54
    • 0035172399 scopus 로고    scopus 로고
    • Antiviral L-nucleosides specific for hepatitis B virus infection
    • Bryant M.L., Bridges E.G., Placidi L., et al. Antiviral L-nucleosides specific for hepatitis B virus infection. Antimicrob Agents Chemother 45 (2001) 229-235
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 229-235
    • Bryant, M.L.1    Bridges, E.G.2    Placidi, L.3
  • 55
    • 0035196639 scopus 로고    scopus 로고
    • Antiviral activity of clevudine [L-FMAU, (1-(2-fluoro-5-methyl-beta, L-arabinofuranosyl) uracil)] against woodchuck hepatitis virus replication and gene expression in chronically infected woodchucks (Marmota monax)
    • Peek S.F., Cote P.J., Jacob J.R., et al. Antiviral activity of clevudine [L-FMAU, (1-(2-fluoro-5-methyl-beta, L-arabinofuranosyl) uracil)] against woodchuck hepatitis virus replication and gene expression in chronically infected woodchucks (Marmota monax). Hepatology 33 (2001) 254-266
    • (2001) Hepatology , vol.33 , pp. 254-266
    • Peek, S.F.1    Cote, P.J.2    Jacob, J.R.3
  • 56
    • 25144450612 scopus 로고    scopus 로고
    • Covalently closed circular DNA is the predominant form of duck hepatitis B virus DNA that persists following transient infection
    • Le Mire M.F., Miller D.S., Foster W.K., et al. Covalently closed circular DNA is the predominant form of duck hepatitis B virus DNA that persists following transient infection. J Virol 79 19 (2005) 12242-12252
    • (2005) J Virol , vol.79 , Issue.19 , pp. 12242-12252
    • Le Mire, M.F.1    Miller, D.S.2    Foster, W.K.3
  • 57
    • 34248668494 scopus 로고    scopus 로고
    • Twenty-four-week clevudine therapy showed potent and sustained antiviral activity in HBeAg-positive chronic hepatitis B
    • Yoo B.C., Kim J.H., Chung Y.H., et al. Twenty-four-week clevudine therapy showed potent and sustained antiviral activity in HBeAg-positive chronic hepatitis B. Hepatology 45 (2007) 1172-1178
    • (2007) Hepatology , vol.45 , pp. 1172-1178
    • Yoo, B.C.1    Kim, J.H.2    Chung, Y.H.3
  • 58
    • 19544391413 scopus 로고    scopus 로고
    • Cirrhosis Asian Lamivudine Multicenter Study Group: Lamivudine for patients with chronic hepatitis B and advanced liver disease
    • Liaw Y.F., Sung J.J.Y., Chow W.C., et al. Cirrhosis Asian Lamivudine Multicenter Study Group: Lamivudine for patients with chronic hepatitis B and advanced liver disease. N Engl J Med 351 (2004) 1521-1531
    • (2004) N Engl J Med , vol.351 , pp. 1521-1531
    • Liaw, Y.F.1    Sung, J.J.Y.2    Chow, W.C.3
  • 59
    • 0006283506 scopus 로고    scopus 로고
    • 3′-Thiacytidine (3TC) delays development of hepatocellular carcinoma (HCC) in woodchucks with experimentally induced chronic woodchuck hepatitis virus (WHV) infection: preliminary results of a lifetime study
    • [abstract]
    • Peek S.F., Toshkov I.A., Erb H.N., et al. 3′-Thiacytidine (3TC) delays development of hepatocellular carcinoma (HCC) in woodchucks with experimentally induced chronic woodchuck hepatitis virus (WHV) infection: preliminary results of a lifetime study. [abstract]. Hepatology 26 (1997) 368A
    • (1997) Hepatology , vol.26
    • Peek, S.F.1    Toshkov, I.A.2    Erb, H.N.3
  • 60
    • 0035890097 scopus 로고    scopus 로고
    • Long-term entecavir treatment results in sustained antiviral efficacy and prolonged life span in the woodchuck model of chronic hepatitis infection
    • Colonno R.J., Genovesi E.V., Medina I., et al. Long-term entecavir treatment results in sustained antiviral efficacy and prolonged life span in the woodchuck model of chronic hepatitis infection. J Infect Dis 184 (2001) 1236-1245
    • (2001) J Infect Dis , vol.184 , pp. 1236-1245
    • Colonno, R.J.1    Genovesi, E.V.2    Medina, I.3
  • 61
    • 0032565689 scopus 로고    scopus 로고
    • Lamivudine therapy of WHV-infected woodchucks
    • Mason W.S., Cullen J., Moraleda G., et al. Lamivudine therapy of WHV-infected woodchucks. Virology 245 (1998) 18-32
    • (1998) Virology , vol.245 , pp. 18-32
    • Mason, W.S.1    Cullen, J.2    Moraleda, G.3
  • 62
    • 0034235528 scopus 로고    scopus 로고
    • Effects of extended lamivudine therapy in Asian patients with chronic hepatitis B
    • Liaw Y.F., Leung N.W.Y., Chang T.T., et al. Effects of extended lamivudine therapy in Asian patients with chronic hepatitis B. Gastroenterology 199 (2000) 172-180
    • (2000) Gastroenterology , vol.199 , pp. 172-180
    • Liaw, Y.F.1    Leung, N.W.Y.2    Chang, T.T.3
  • 63
    • 0032817797 scopus 로고    scopus 로고
    • Emergence of drug-resistant populations of woodchuck hepatitis virus in woodchucks treated with the antiviral nucleoside lamivudine
    • Zhou T., Saputelli J., Aldrich C.E., et al. Emergence of drug-resistant populations of woodchuck hepatitis virus in woodchucks treated with the antiviral nucleoside lamivudine. Antimicrob Agents Chemother 43 8 (1999) 1947-1954
    • (1999) Antimicrob Agents Chemother , vol.43 , Issue.8 , pp. 1947-1954
    • Zhou, T.1    Saputelli, J.2    Aldrich, C.E.3
  • 64
    • 0035997941 scopus 로고    scopus 로고
    • Mutations in the conserved woodchuck hepatitis virus polymerase FLLA and YMDD regions conferring resistance to lamivudine
    • Tatti K.M., Korba B.E., Stang H.L., et al. Mutations in the conserved woodchuck hepatitis virus polymerase FLLA and YMDD regions conferring resistance to lamivudine. Antiviral Res 55 (2002) 141-150
    • (2002) Antiviral Res , vol.55 , pp. 141-150
    • Tatti, K.M.1    Korba, B.E.2    Stang, H.L.3
  • 65
    • 4043150025 scopus 로고    scopus 로고
    • Suppression of lamivudine-resistant B-domain mutants by adefovir dipivoxil in the woodchuck hepatitis virus model
    • Jacob J.R., Korba B.E., Cote P.J., et al. Suppression of lamivudine-resistant B-domain mutants by adefovir dipivoxil in the woodchuck hepatitis virus model. Antiviral Res 63 (2004) 115-121
    • (2004) Antiviral Res , vol.63 , pp. 115-121
    • Jacob, J.R.1    Korba, B.E.2    Cote, P.J.3
  • 66
    • 0033868988 scopus 로고    scopus 로고
    • Enhanced antiviral benefit of combination therapy with lamivudine and alpha interferon against WHV replication in chronic carrier woodchucks
    • Korba B.E., Cote P., Hornbuckle W., et al. Enhanced antiviral benefit of combination therapy with lamivudine and alpha interferon against WHV replication in chronic carrier woodchucks. Antivir Ther 5 (2000) 95-104
    • (2000) Antivir Ther , vol.5 , pp. 95-104
    • Korba, B.E.1    Cote, P.2    Hornbuckle, W.3
  • 67
    • 0036623206 scopus 로고    scopus 로고
    • Lamivudine/interferon combination therapy in anti-HBe positive chronic hepatitis B patients: a controlled pilot study
    • Santantonio T., Niro G.A., Sinisi E., et al. Lamivudine/interferon combination therapy in anti-HBe positive chronic hepatitis B patients: a controlled pilot study. J Hepatol 36 6 (2002) 799-804
    • (2002) J Hepatol , vol.36 , Issue.6 , pp. 799-804
    • Santantonio, T.1    Niro, G.A.2    Sinisi, E.3
  • 68
    • 27944436136 scopus 로고    scopus 로고
    • Interferon-alpha plus lamivudine vs lamivudine reduces breakthroughs, but does not affect sustained response in HBeAg negative chronic hepatitis B
    • Economou M., Manolakopoulous S., Trikalinos T.A., et al. Interferon-alpha plus lamivudine vs lamivudine reduces breakthroughs, but does not affect sustained response in HBeAg negative chronic hepatitis B. World J Gastroenterol 11 37 (2005) 5882-5887
    • (2005) World J Gastroenterol , vol.11 , Issue.37 , pp. 5882-5887
    • Economou, M.1    Manolakopoulous, S.2    Trikalinos, T.A.3
  • 69
    • 33644804410 scopus 로고    scopus 로고
    • Interferon/long-term lamivudine combination therapy in anti-HBe positive chronic hepatitis B patients
    • Nikolaidis N.L., Giouleme O.I., Tziomalos K.A., et al. Interferon/long-term lamivudine combination therapy in anti-HBe positive chronic hepatitis B patients. J Gastroenterol Hepatol 20 11 (2005) 1721-1725
    • (2005) J Gastroenterol Hepatol , vol.20 , Issue.11 , pp. 1721-1725
    • Nikolaidis, N.L.1    Giouleme, O.I.2    Tziomalos, K.A.3
  • 70
    • 21244447705 scopus 로고    scopus 로고
    • Peginterferon Alpha-2a, lamivudine, and the combination for HbeAg-positive chronic hepatitis B
    • Lau G.K., Piratvisuth T., Luo K.X., et al. Peginterferon Alpha-2a, lamivudine, and the combination for HbeAg-positive chronic hepatitis B. N Engl J Med 352 26 (2005) 2682-2695
    • (2005) N Engl J Med , vol.352 , Issue.26 , pp. 2682-2695
    • Lau, G.K.1    Piratvisuth, T.2    Luo, K.X.3
  • 71
    • 17444431576 scopus 로고    scopus 로고
    • Effect of antiviral treatment with entecavir on age- and dose-related outcomes of duck hepatitis B virus infection
    • Foster W.K., Miller D.S., Scougall C.A., et al. Effect of antiviral treatment with entecavir on age- and dose-related outcomes of duck hepatitis B virus infection. J Virol 79 9 (2005) 5819-5832
    • (2005) J Virol , vol.79 , Issue.9 , pp. 5819-5832
    • Foster, W.K.1    Miller, D.S.2    Scougall, C.A.3
  • 72
    • 0041828226 scopus 로고    scopus 로고
    • Induction of antibodies to the PreS region of surface antigens of woodchuck hepatitis virus (WHV) in chronic carrier woodchucks by immunizations with WHV surface antigens
    • Lu M., Klaes R., Menne S., et al. Induction of antibodies to the PreS region of surface antigens of woodchuck hepatitis virus (WHV) in chronic carrier woodchucks by immunizations with WHV surface antigens. J Hepatol 39 (2003) 405-413
    • (2003) J Hepatol , vol.39 , pp. 405-413
    • Lu, M.1    Klaes, R.2    Menne, S.3
  • 73
    • 0036098137 scopus 로고    scopus 로고
    • Immunization with surface antigen vaccine alone and after treatment wit 1-(2-Fluoro-5-Methyl-B-L_Arabinofuranosy)-Uracil (L-FMAU) breaks humoral and cell-mediated immune tolerance in chronic woodchuck hepatitis virus infection
    • Menne S., Roneker C.A., Korba B.E., et al. Immunization with surface antigen vaccine alone and after treatment wit 1-(2-Fluoro-5-Methyl-B-L_Arabinofuranosy)-Uracil (L-FMAU) breaks humoral and cell-mediated immune tolerance in chronic woodchuck hepatitis virus infection. J Virol 76 11 (2002) 5305-5314
    • (2002) J Virol , vol.76 , Issue.11 , pp. 5305-5314
    • Menne, S.1    Roneker, C.A.2    Korba, B.E.3
  • 74
    • 11144252249 scopus 로고    scopus 로고
    • Clevudine therapy with vaccine inhibits progression of chronic hepatitis and delays onset of hepatocellular carcinoma in chronic woodchuck hepatitis virus infection
    • Korba B.E., Cote P.J., Menne S., et al. Clevudine therapy with vaccine inhibits progression of chronic hepatitis and delays onset of hepatocellular carcinoma in chronic woodchuck hepatitis virus infection. Antivir Ther 9 (2004) 937-952
    • (2004) Antivir Ther , vol.9 , pp. 937-952
    • Korba, B.E.1    Cote, P.J.2    Menne, S.3
  • 75
    • 0036983178 scopus 로고    scopus 로고
    • Immunogenic effects of woodchuck hepatitis virus surface antigen vaccine in combination with antiviral therapy: breaking of humoral and cellular immune tolerance in chronic woodchuck hepatitis virus infection
    • Menne S., Roneker C.A., Tennant B.C., et al. Immunogenic effects of woodchuck hepatitis virus surface antigen vaccine in combination with antiviral therapy: breaking of humoral and cellular immune tolerance in chronic woodchuck hepatitis virus infection. Intervirology 45 (2002) 237-250
    • (2002) Intervirology , vol.45 , pp. 237-250
    • Menne, S.1    Roneker, C.A.2    Tennant, B.C.3
  • 76
    • 0037487048 scopus 로고    scopus 로고
    • Ultrasonography in the study of hepatocellular carcinoma in woodchucks chronically infected with WHV
    • Lisi D., Kondili L.A., Ramieri M.T., et al. Ultrasonography in the study of hepatocellular carcinoma in woodchucks chronically infected with WHV. Lab Anim 37 3 (2003) 233-240
    • (2003) Lab Anim , vol.37 , Issue.3 , pp. 233-240
    • Lisi, D.1    Kondili, L.A.2    Ramieri, M.T.3
  • 77
    • 0032040130 scopus 로고    scopus 로고
    • Sonographic depiction of woodchuck hepatomas using intravenously injected contrast agents
    • Nada T., Moriyasu F., Kono Y., et al. Sonographic depiction of woodchuck hepatomas using intravenously injected contrast agents. Nippon Rinsho 56 4 (1998) 980-984
    • (1998) Nippon Rinsho , vol.56 , Issue.4 , pp. 980-984
    • Nada, T.1    Moriyasu, F.2    Kono, Y.3
  • 78
    • 33744822437 scopus 로고    scopus 로고
    • Chronic care and monitoring of woodchucks during repeated magnetic resonance imaging of the liver
    • McKenzie E.J., Jackson M., Turner A., et al. Chronic care and monitoring of woodchucks during repeated magnetic resonance imaging of the liver. J Am Assoc Lab Anim Sci 45 2 (2006) 26-30
    • (2006) J Am Assoc Lab Anim Sci , vol.45 , Issue.2 , pp. 26-30
    • McKenzie, E.J.1    Jackson, M.2    Turner, A.3
  • 79
    • 34248176916 scopus 로고    scopus 로고
    • Quantitative evaluation of 2-deoxy-2[f-18]fluoro-D:-glucose-positron emission tomography imaging on the woodchuck model of hepatocellular carcinoma with histologic correlation
    • Salem N., Maclennan G.T., Kuang Y., et al. Quantitative evaluation of 2-deoxy-2[f-18]fluoro-D:-glucose-positron emission tomography imaging on the woodchuck model of hepatocellular carcinoma with histologic correlation. Mol Imaging Biol 9 3 (2007) 135-143
    • (2007) Mol Imaging Biol , vol.9 , Issue.3 , pp. 135-143
    • Salem, N.1    Maclennan, G.T.2    Kuang, Y.3
  • 80
    • 0036678190 scopus 로고    scopus 로고
    • A new model of hepatitis B virus reinfection: liver transplantation in the woodchuck
    • Dahmen U., Li J., Dirsch O., et al. A new model of hepatitis B virus reinfection: liver transplantation in the woodchuck. Transplantation 74 3 (2002) 373-380
    • (2002) Transplantation , vol.74 , Issue.3 , pp. 373-380
    • Dahmen, U.1    Li, J.2    Dirsch, O.3
  • 81
    • 1942420238 scopus 로고    scopus 로고
    • Adoptive transfer of immunity: a new strategy to interfere with severe hepatitis virus reinfection after woodchuck liver transplantation
    • Dahmen U., Dirsch O., Li J., et al. Adoptive transfer of immunity: a new strategy to interfere with severe hepatitis virus reinfection after woodchuck liver transplantation. Transplantation 77 7 (2004) 965-972
    • (2004) Transplantation , vol.77 , Issue.7 , pp. 965-972
    • Dahmen, U.1    Dirsch, O.2    Li, J.3
  • 82
    • 35549006823 scopus 로고    scopus 로고
    • Gene expression studies of hepatitis virus-induced woodchuck hepatocellular carcinoma in correlation with human results
    • Wang F., Anderson P.W., Salem N., et al. Gene expression studies of hepatitis virus-induced woodchuck hepatocellular carcinoma in correlation with human results. Int J Oncol 30 1 (2007) 33-44
    • (2007) Int J Oncol , vol.30 , Issue.1 , pp. 33-44
    • Wang, F.1    Anderson, P.W.2    Salem, N.3
  • 83
    • 0347635488 scopus 로고    scopus 로고
    • Residual integrated viral DNA after hepadnavirus clearance by nucleoside analog therapy
    • Summers J., and Mason W.S. Residual integrated viral DNA after hepadnavirus clearance by nucleoside analog therapy. Proc Natl Acad Sci USA 101 2 (2004) 638-640
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.2 , pp. 638-640
    • Summers, J.1    Mason, W.S.2
  • 84
    • 33947379234 scopus 로고    scopus 로고
    • Immunosupression reactivates viral replication long after resolution of woodchuck hepatitis virus infection
    • Menne S., Cote P.J., Butler S.D., et al. Immunosupression reactivates viral replication long after resolution of woodchuck hepatitis virus infection. Hepatology 45 3 (2007) 614-622
    • (2007) Hepatology , vol.45 , Issue.3 , pp. 614-622
    • Menne, S.1    Cote, P.J.2    Butler, S.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.