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Volumn 45, Issue 10, 2001, Pages 2740-2745

Antiviral efficacy and pharmacokinetics of oral adefovir dipivoxil in chronically woodchuck hepatitis virus-infected woodchucks

(8) Cullen, J M a Li, D H a Brown, C a Eisenberg, E J a Cundy, K C a Wolfe, J a Toole, J a Gibbs, C a

a NORTH CAROLINA STATE UNIVERSITY (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADEFOVIR DIPIVOXIL; BICARBONATE; LACTIC ACID; VIRUS DNA; VIRUS RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; BLOOD CHEMISTRY; BODY WEIGHT; CONTROLLED STUDY; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG EFFICACY; DRUG HALF LIFE; FEMALE; HEPATITIS; HEPATITIS VIRUS; HISTOPATHOLOGY; LIVER BIOPSY; LIVER INJURY; MALE; NONHUMAN; PRIORITY JOURNAL; WOODCHUCK;

ADENINE; ADMINISTRATION, ORAL; ANIMALS; CHEMISTRY, CLINICAL; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; DNA, VIRAL; HEPATITIS B; HEPATITIS B VIRUS, WOODCHUCK; LIVER; MARMOTA; PHOSPHONIC ACIDS; TREATMENT OUTCOME;

EID: 0034806770 PISSN: 00664804 EISSN: None Source Type: Journal
DOI: 10.1128/AAC.45.10.2740-2745.2001 Document Type: Article

Times cited : (39)

References (32)

1
- 0003303887
- Marked in vivo antiretrovirus activity of 9-(2-phosponylmethoxyethyl) adenine, a selective anti-human immunodeficiency virus agent
- (1991) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 332-336
- Balzarini, J.¹ Naesens, L.² Herdewijn, P.³ Rosenberg, I.⁴ Holy, A.⁵ Pauwels, R.⁶ Baba, M.⁷ Johns, D.G.⁸ De Clercq, E.⁹

2
- 0025979184
- 9-(2-Phosphonylmethoxyethyl) adenine (PMEA) effective inhibits retrovirus replication in vitro and simian immunodeficiency virus infection in rhesus monkeys
- (1991) AIDS , vol.5 , pp. 21-28
- Balzarini, J.¹ Naesens, L.² Slachmuylders, J.³ Niphuis, H.⁴ Rosenberg, I.⁵ Holy, A.⁶ Schellekens, H.⁷ De Clercq, E.⁸

3
- 0030842430
- Anti-human immunodeficiency virus (HIV) activity, safety, and pharmacokinetics of adefovir dipivoxil (9-[2-(bis-pivaloyloxymethyl)-phosphonylmethowethyl] adenine) in HIV-infected patients
- (1997) J. Infect. Dis. , vol.176 , pp. 406-413
- Barditch-Crovo, P.¹ Toole, J.H.C.W.² Cundy, K.C.³ Ebeling, D.⁴ Jaffe, H.S.⁵ Lietman, P.S.⁶

4
- 0029866581
- Mechanisms for the anti-hepatitis B virus activity and mitochondrial toxicity of fialuridine
- (1996) Antivir. Res. , vol.29 , pp. 125-139
- Colacino, J.M.¹

5
- 0033999389
- In vitro antihepadnaviral activities of combinations of penciclovir, lamivudine, and adefovir
- (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 551-560
- Colledge, D.¹ Civitico, G.² Locarnini, S.³ Shaw, T.⁴

6
- 0030754358
- In vivo antiviral activity and pharmacokinetics of (-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine in woodchuck hepatitis virus-infected woodchucks
- (1997) Antimicrob. Agents Chemother. , vol.41 , pp. 2076-2082
- Cullen, J.M.¹ Smith, S.L.² Davis, M.G.³ Dunn, S.E.⁴ Botteron, C.⁵ Cecchi, A.⁶ Linsey, D.⁷ Linzey, D.⁸ Frick, L.⁹ Paff, M.¹⁰ Goulding, A.¹¹ Biron, K.¹²

7
- 0028286804
- Oral bioavailability of the antiretroviral agent 9-2(phosphonylmethoxyethyl) adenine (PMEA) from three formulations of the prodrug bis(pivaloyloxymethyl) PMEA in fasted male cynomolgus monkeys
- (1994) Pharm. Res. , vol.11 , pp. 839-843
- Cundy, K.C.¹ Fishback, J.A.² Shaw, J.P.³ Lee, M.L.⁴ Soike, K.F.⁵ Visor, G.C.⁶ Lee, W.A.⁷

8
- 0031445754
- Oral formulations of adefovir dipivoxil: In vitro dissolution and in vivo bioavailability in dogs
- (1997) J. Pharm. Sci. , vol.86 , pp. 1334-1338
- Cundy, K.C.¹ Sue, I.L.² Visor, G.C.³ Marshburn, J.⁴ Nakamura, C.⁵ Lee, W.A.⁶ Shaw, J.P.⁷

9
- 0034234540
- Increased hepatocyte turnover and inhibition of woodchuck hepatitis B virus replication by adefovir in vitro do not lead to reduction of the closed circular DNA
- (2000) Hepatology , vol.32 , pp. 139-146
- Dandri, M.¹ Burda, M.R.² Will, H.³ Petersen, J.⁴

10
- 0025837774
- Broad-spectrum anti-DNA virus and anti-retrovirus activity of phosphonylmethoxyalkylpurines and pyrimidines
- (1991) Biochem. Pharmacol. , vol.42 , pp. 963-972
- De Clereq, E.¹

11
- 0030722272
- The safety and efficacy of adefovir dipivoxil, a novel anti-human immunodeficiency virus (HIV) therapy, in HIV-infected adults: A randomized, double-blind, placebo-controlled trial
- (1997) J. Infect. Dis. , vol.176 , pp. 1517-1523
- Deeks, S.G.¹ Collier, A.² Lalezari, J.³ Pavia, A.⁴ Rodrigue, D.⁵ Drew, W.L.⁶ Toole, J.⁷ Jaffe, H.S.⁸ Mulato, A.S.⁹ Lamy, P.D.¹⁰ Li, W.¹¹ Cherrington, J.M.¹² Hellmann, N.¹³ Kahn, J.¹⁴

12
- 0023549354
- Main properties of duck hepatitis B virus DNA polymerase: Comparison with the human and woodchuck hepatitis B virus DNA polymerases
- (1987) Antivir. Res. , vol.8 , pp. 189-199
- Fourel, I.¹ Hantz, O.² Cora, L.³ Allaudeen, H.S.⁴ Trepo, C.⁵

13
- 0032885698
- A placebo-controlled phase I/II study of adefovir dipivoxil in patients with chronic hepatitis B virus infection
- (1999) J. Viral Hepatitis , vol.6 , pp. 387-395
- Gilson, R.J.¹ Chopra, K.B.² Newell, A.M.³ Murray-Lyon, I.M.⁴ Nelson, M.R.⁵ Rice, S.J.⁶ Tedder, R.S.⁷ Toole, J.⁸ Jaffe, H.S.⁹ Weller, I.V.¹⁰

14
- 0031927053
- Therapy of viral hepatitis
- (1998) Digestion , vol.59 , pp. 563-578
- Hoofnagle, J.H.¹

15
- 0029784673
- Global status of HBV immunization
- (1996) Lancet , vol.348 , pp. 696
- Kane, M.¹

16
- 0030997076
- Histopathologic changes associated with fialuridine hepatotoxicity
- (1997) Mod. Pathol. , vol.10 , pp. 192-199
- Kleiner, D.E.¹ Gaffey, M.J.² Sallie, R.³ Tsokos, M.⁴ Nichols, L.⁵ McKenzie, R.⁶ Strauss, S.E.⁷ Hoofnagle, J.H.⁸

17
- 0030001773
- Liver-targeted antiviral nucleosides: Enhanced antiviral activity of phosphatidyl-dideoxyguanosine versus dideoxyguanosine in woodchuck hepatitis virus infection in vivo
- (1996) Hepatology , vol.23 , pp. 958-963
- Korba, B.A.¹ Xie, H.² Wright, K.N.³ Hornbuckle, W.E.⁴ Gerin, J.L.⁵ Tennant, B.C.⁶ Hostetler, K.Y.⁷

18
- 0034011592
- Treatment of chronic woodchuck hepatitis virus infection in the eastern woodchuck (Marmota monax) with nucleoside analogues is predictive of therapy for chronic hepatitis B virus in man
- (2000) Hepatology , vol.31 , pp. 1165-1175
- Korba, B.E.¹ Cote, P.² Hornbuckle, W.³ Tennant, B.C.⁴ Gerin, J.L.⁵

19
- 0034089899
- Effect of oral administration of emtricitabine on woodchuck hepatitis virus replication in chronically infected woodchucks
- (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 1757-1760
- Korba, B.E.¹ Schinazi, R.F.² Cote, P.³ Tennant, B.C.⁴ Gerin, J.L.⁵

20
- 0021706452
- Neurotoxicity associated with adenine arabinoside monophosphate in the treatment of chronic hepatitis B virus infection
- (1984) J. Antimicrob. Chemother. , vol.14 , pp. 93-99
- Lok, A.S.¹ Wilson, L.A.² Thomas, H.C.³

21
- 0025908305
- Development of antiviral therapy for chronic infection with hepatitis B virus
- (1991) Curr. Top. Microbiol. Immunol. , vol.168 , pp. 167-183
- Marion, P.L.¹

22
- 0032565689
- Lamivudine therapy of WHV-infected woodchucks
- (1998) Virology , vol.245 , pp. 18-32
- Mason, W.S.¹ Cullen, J.M.² Moraleda, G.³ Saputelli, J.⁴ Aldrich, C.E.⁵ Miller, D.S.⁶ Tennant, B.C.⁷ Frick, L.⁸ Averett, D.⁹ Condreay, L.D.¹⁰ Jilbert, A.R.¹¹

23
- 0028817865
- Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B
- (1995) N. Engl. J. Med. , vol.333 , pp. 1099-1105
- McKensie, R.¹ Fried, M.W.² Sallie, R.³ Conjeevaram, H.⁴ DiBisceglie, A.M.⁵ Park, Y.⁶ Savarese, B.⁷ Kleiner, D.⁸ Tsokos, M.⁹ Luciano, C.¹⁰ Pruett, T.¹¹ Stotka, J.L.¹² Straus, S.E.¹³ Hoofnagle, J.H.¹⁴

24
- 0031728650
- Inhibition of duck hepatitis virus replication by 9-(2-phosphonylmethoxymethyl)adenine, an acyclic phosphonate nucleoside analogue
- (1998) Antimicrob. Agents Chemother. , vol.42 , pp. 3130-3135
- Nicoll, A.J.¹ Colledge, D.L.² Toole, J.J.³ Angus, P.W.⁴ Smallwood, R.A.⁵ Locarnini, S.A.⁶

25
- 0025767013
- Cellular uptake of phosphonylmethoxyalkylpurine derivatives
- (1991) Antivir. Res. , vol.16 , pp. 115-119
- Palu, G.¹ Stefanelli, S.² Rassu, M.³ Parolin, C.⁴ Balzarini, J.⁵ De Clereq, E.⁶

26
- 0028809476
- The woodchuck: An animal model for hepatitis B virus infection in man
- (1995) Intervirology , vol.38 , pp. 100-112
- Roggendorf, M.¹ Tolle, T.K.²

27
- 0030997246
- Pharmacokinetics and metabolism of selected prodrugs of PMEA in rats
- (1997) Drug Metab. Dispos. , vol.25 , pp. 362-366
- Shaw, J.P.¹ Louie, M.S.² Krishnamurthy, V.V.³ Arimilli, M.N.⁴ Jones, J.J.⁵ Bidgood, A.M.⁶ Lee, W.A.⁷ Cundy, K.C.⁸

28
- 0029047348
- Hepatic purine and pyrimidine metabolism: Implications for antiviral chemotherapy of viral hepatitis
- (1995) Liver , vol.15 , pp. 169-184
- Shaw, T.¹ Locarnini, S.²

29
- 0025995441
- Hepadnaviruses and hepatocellular carcinoma
- (1991) Annu. Rev. Microbiol. , vol.45 , pp. 475-507
- Sherker, A.H.¹ Marion, P.L.²

30
- 0031741017
- Severe anemia following combined alpha-interferon/ribavirin therapy of chronic hepatitis C
- (1998) J. Hepatol. , vol.29 , pp. 1033-1034
- Tappero, G.¹ Ballare, M.² Farina, M.³ Negro, F.⁴

31
- 17344366353
- Antiviral activity and toxicity of fialuridine in the woodchuck model of hepatitis B virus infection
- (1998) Hepatology , vol.28 , pp. 179-191
- Tennant, B.C.¹ Baldwin, B.H.² Graham, L.A.³ Ascenzi, M.A.⁴ Hornbuckle, W.E.⁵ Rowland, P.H.⁶ Tochkov, I.A.⁷ Yeager, A.E.⁸ Erb, H.N.⁹ Colacino, J.M.¹⁰ Lopez, C.¹¹ Engelhardt, J.A.¹² Bowsher, R.R.¹³ Richardson, F.C.¹⁴ Lewis, W.¹⁵ Cote, P.J.¹⁶ Korba, B.E.¹⁷ Gerin, J.L.¹⁸

32
- 0025924186
- Inhibitory effects of selected antiviral compounds on human hepatitis B virus DNA synthesis
- (1991) Antimicrob. Agents Chemother. , vol.35 , pp. 394-397
- Yokuta, T.¹ Mochizuki, S.² Konno, K.³ Mori, S.⁴ Shigeta, S.⁵ De Clereq, E.⁶

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