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Volumn 13, Issue 3, 2002, Pages 165-176

Viral pharmacodynamic model for (-)-β-2′,3′-dideoxy-5- fluoro-3′-thiacytidine (emtricitabine) in chronically infected woodchucks

Author keywords

Antiviral agents; Covaricil; Emtricitabine; Pharmacodynamics; Woodchucks

Indexed keywords

EMTRICITABINE; DEOXYCYTIDINE; DRUG DERIVATIVE;

EID: 2342631429     PISSN: 09563202     EISSN: None     Source Type: Journal    
DOI: 10.1177/095632020201300303     Document Type: Article
Times cited : (2)

References (50)
  • 3
    • 0032874225 scopus 로고    scopus 로고
    • Quantitation of intracellular triphosphate of emtricitabine in peripheral blood mononuclear cells from human immunodeficiency virus-infected patients
    • Darque A, Valette G, Rousseau F, Wang LH, Sommadossi JP & Zhou XJ (1999). Quantitation of intracellular triphosphate of emtricitabine in peripheral blood mononuclear cells from human immunodeficiency virus-infected patients. Antimicrobial Agents and Chemotherapy 43:2245-2250.
    • (1999) Antimicrobial Agents and Chemotherapy , vol.43 , pp. 2245-2250
    • Darque, A.1    Valette, G.2    Rousseau, F.3    Wang, L.H.4    Sommadossi, J.P.5    Zhou, X.J.6
  • 6
    • 0028102990 scopus 로고
    • Evidence that hepatocyte turnover is required for rapid clearance of duck hepatitis B virus during antiviral therapy of chronically infected ducks
    • Fourel I, Cullen JM, Saputelli J, Aldrich CE, Schaffer P, Averett DR, Pugh J & Mason WS (1994). Evidence that hepatocyte turnover is required for rapid clearance of duck hepatitis B virus during antiviral therapy of chronically infected ducks. Journal of Virology 68:8321-8330.
    • (1994) Journal of Virology , vol.68 , pp. 8321-8330
    • Fourel, I.1    Cullen, J.M.2    Saputelli, J.3    Aldrich, C.E.4    Schaffer, P.5    Averett, D.R.6    Pugh, J.7    Mason, W.S.8
  • 10
    • 0026483089 scopus 로고
    • Enzyme-mediated enantioselective preparation of the antiviral agent 2′,3′-dideoxy-5-fluoro-3′-thiacytidine (FTC) and related compounds
    • Hoong LK, Strange LE, Liotta DC, Koszalka GW, Burns CL &, Schinazi RF (1992). Enzyme-mediated enantioselective preparation of the antiviral agent 2′,3′-dideoxy-5-fluoro-3′-thiacytidine (FTC) and related compounds. Journal of Organic Chemistry 57:5563-5565.
    • (1992) Journal of Organic Chemistry , vol.57 , pp. 5563-5565
    • Hoong, L.K.1    Strange, L.E.2    Liotta, D.C.3    Koszalka, G.W.4    Burns, C.L.5    Schinazi, R.F.6
  • 11
    • 0031782844 scopus 로고    scopus 로고
    • Pharmacodynamics of (-)-β-2′,3′-dideoxy-3′- thiacytidine (3TC) in chronically virus-infected woodchucks compared to its pharmacodynamics in humans
    • Hurwitz SJ, Tennant BC, Korba BE, Gerin JL & Schinazi RF (1998). Pharmacodynamics of (-)-β-2′,3′-dideoxy-3′-thiacytidine (3TC) in chronically virus-infected woodchucks compared to its pharmacodynamics in humans. Antimicrobial Agents and Chemotherapy 42:2804-2809.
    • (1998) Antimicrobial Agents and Chemotherapy , vol.42 , pp. 2804-2809
    • Hurwitz, S.J.1    Tennant, B.C.2    Korba, B.E.3    Gerin, J.L.4    Schinazi, R.F.5
  • 12
    • 0027943266 scopus 로고
    • Physiologic indirect response models characterize diverse types of pharmacodynamic effects
    • Jusko WJ, Hui C & Ko MS (1994). Physiologic indirect response models characterize diverse types of pharmacodynamic effects. Clinical Pharmacology & Therapeutics 56:406-419.
    • (1994) Clinical Pharmacology & Therapeutics , vol.56 , pp. 406-419
    • Jusko, W.J.1    Hui, C.2    Ko, M.S.3
  • 14
    • 0027941175 scopus 로고
    • Woodchuck hepatitis virus infections: Very rapid recovery after a prolonged viremia and infection of virtually every hepatocyte
    • Kajino K, Jilbert AR, Saputelli J, Aldrich CE, Cullen J & Mason WS (1994). Woodchuck hepatitis virus infections: very rapid recovery after a prolonged viremia and infection of virtually every hepatocyte. Journal of Virology 68:5792-5803.
    • (1994) Journal of Virology , vol.68 , pp. 5792-5803
    • Kajino, K.1    Jilbert, A.R.2    Saputelli, J.3    Aldrich, C.E.4    Cullen, J.5    Mason, W.S.6
  • 15
    • 0023215276 scopus 로고
    • Lymphoid cells in the spleens of woodchuck hepatitis virus-infected woodchucks are a site of active viral replication
    • Korba BE, Wells F, Tennant BC, Cote PJ & Gerin JL (1987). Lymphoid cells in the spleens of woodchuck hepatitis virus-infected woodchucks are a site of active viral replication. Journal of Virology 61:1318-1324.
    • (1987) Journal of Virology , vol.61 , pp. 1318-1324
    • Korba, B.E.1    Wells, F.2    Tennant, B.C.3    Cote, P.J.4    Gerin, J.L.5
  • 16
    • 0034089899 scopus 로고    scopus 로고
    • Effect of oral administration of emtricitabine on woodchuck hepatitis virus replication in chronically infected woodchucks
    • Korba BE, Schinazi RF, Cote P, Tennant BC & Gerin JL (2000a). Effect of oral administration of emtricitabine on woodchuck hepatitis virus replication in chronically infected woodchucks. Antimicrobial Agents and Chemotherapy 44:1757-1760.
    • (2000) Antimicrobial Agents and Chemotherapy , vol.44 , pp. 1757-1760
    • Korba, B.E.1    Schinazi, R.F.2    Cote, P.3    Tennant, B.C.4    Gerin, J.L.5
  • 17
    • 0034011592 scopus 로고    scopus 로고
    • Treatment of chronic woodchuck hepatitis virus infection in the Eastern woodchuck (Marmota monax) with nucleoside analogues is predictive of therapy for chronic hepatitis B virus infection in humans
    • Korba BE, Cote P, Hornbuckle W, Tennant BC & Gerin JL. (2000b). Treatment of chronic woodchuck hepatitis virus infection in the Eastern woodchuck (Marmota monax) with nucleoside analogues is predictive of therapy for chronic hepatitis B virus infection in humans. Hepatology 31:1165-1175.
    • (2000) Hepatology , vol.31 , pp. 1165-1175
    • Korba, B.E.1    Cote, P.2    Hornbuckle, W.3    Tennant, B.C.4    Gerin, J.L.5
  • 18
    • 0032463380 scopus 로고    scopus 로고
    • Characterization of pharmacodynamic recession slopes for direct and indirect response models
    • Krzyzanski W & Jusko WJ (1998). Characterization of pharmacodynamic recession slopes for direct and indirect response models. Journal of Pharmacokinetics and Biopharmaceutics 26:409-437
    • (1998) Journal of Pharmacokinetics and Biopharmaceutics , vol.26 , pp. 409-437
    • Krzyzanski, W.1    Jusko, W.J.2
  • 23
    • 0024520582 scopus 로고
    • Experimental systems for the study of hepadnavirus and delta virus infections
    • Mason WS & Taylor JM (1989). Experimental systems for the study of hepadnavirus and delta virus infections. Hepatology 9:635-645.
    • (1989) Hepatology , vol.9 , pp. 635-645
    • Mason, W.S.1    Taylor, J.M.2
  • 26
    • 0029037074 scopus 로고
    • The covalently closed duplex form of the hepadnavirus genome exists in situ as a heterogeneous population of viral minichromosomes
    • Newbold JE, Xin H, Tencza M, Sherman G, Dean J, Bowden S & Locarnini S (1995). The covalently closed duplex form of the hepadnavirus genome exists in situ as a heterogeneous population of viral minichromosomes. Journal of Virology 69:3350-3357.
    • (1995) Journal of Virology , vol.69 , pp. 3350-3357
    • Newbold, J.E.1    Xin, H.2    Tencza, M.3    Sherman, G.4    Dean, J.5    Bowden, S.6    Locarnini, S.7
  • 28
    • 0031581661 scopus 로고    scopus 로고
    • Anti-viral drug treatment: Dynamics of resistance in free virus and infected cell populations
    • Novak MA, Bonhoefer S, Shaw GM & May RM (1997). Anti-viral drug treatment: dynamics of resistance in free virus and infected cell populations. Journal of Theoretical Biology 184:203-217.
    • (1997) Journal of Theoretical Biology , vol.184 , pp. 203-217
    • Novak, M.A.1    Bonhoefer, S.2    Shaw, G.M.3    May, R.M.4
  • 30
    • 0028260316 scopus 로고
    • Intracellular metabolism of (-)- And (+)-cis-5-fluoro-1-[2- (hydroxymethyl)-1,3-oxathiolan-5-yl]-cytosine in HepG2 derivative 2.215 (Subclone P5A) cells
    • Paff MT, Averett DR, Prus KL, Miller WH & Nelson DJ (1994). Intracellular metabolism of (-)- and (+)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3- oxathiolan-5-yl]-cytosine in HepG2 derivative 2.215 (Subclone P5A) cells. Antimicrobial Agents and Chemotherapy 38:1230-1238.
    • (1994) Antimicrobial Agents and Chemotherapy , vol.38 , pp. 1230-1238
    • Paff, M.T.1    Averett, D.R.2    Prus, K.L.3    Miller, W.H.4    Nelson, D.J.5
  • 31
    • 0030026113 scopus 로고    scopus 로고
    • Reduction of HIV concentrations during acute infection: Independence from a specific immune response
    • Phillips AN (1996). Reduction of HIV concentrations during acute infection: independence from a specific immune response. Science 271:497-499
    • (1996) Science , vol.271 , pp. 497-499
    • Phillips, A.N.1
  • 32
    • 0028809476 scopus 로고
    • The woodchuck, an animal model for hepatitis B virus infection in man
    • Roggendorf M & Tolle TK (1995). The woodchuck, an animal model for hepatitis B virus infection in man. Intervirology 38:100-112.
    • (1995) Intervirology , vol.38 , pp. 100-112
    • Roggendorf, M.1    Tolle, T.K.2
  • 35
    • 0005899598 scopus 로고    scopus 로고
    • Comparative activation of 2¢-deoxycytidine and antiviral oxathiolane cytosine nucleosides by different mammalian liver extracts
    • Schinazi RF, Hough LM, Juodawlkis A, Marion P & Tennant B (1997). Comparative activation of 2¢-deoxycytidine and antiviral oxathiolane cytosine nucleosides by different mammalian liver extracts. Antiviral Research 34:A65.
    • (1997) Antiviral Research , vol.34
    • Schinazi, R.F.1    Hough, L.M.2    Juodawlkis, A.3    Marion, P.4    Tennant, B.5
  • 40
    • 0029047348 scopus 로고
    • Hepatic purine and pyrimidine metabolism: Implications for antiviral chemotherapy of viral hepatitis
    • Shaw T & Locarnini S (1995). Hepatic purine and pyrimidine metabolism: implications for antiviral chemotherapy of viral hepatitis. Liver 15:169-184.
    • (1995) Liver , vol.15 , pp. 169-184
    • Shaw, T.1    Locarnini, S.2
  • 41
    • 0027417199 scopus 로고
    • Affinity of the antiviral enantiomers of oxathiolane cytosine nucleosides for human 2′-deoxycytidine kinase
    • Shewach DS, Liotta DC & Schinazi RF (1993). Affinity of the antiviral enantiomers of oxathiolane cytosine nucleosides for human 2′- deoxycytidine kinase. Biochemical Pharmacology 45:1540-1543.
    • (1993) Biochemical Pharmacology , vol.45 , pp. 1540-1543
    • Shewach, D.S.1    Liotta, D.C.2    Schinazi, R.F.3
  • 42
    • 0019289897 scopus 로고
    • Evaluation of methods for estimating population pharmacokinetic parameters. I. Michaelis-Menton model; routine clinical pharmacokinetic data
    • Sheiner LB & Beal S (1980). Evaluation of methods for estimating population pharmacokinetic parameters. I. Michaelis-Menton model; routine clinical pharmacokinetic data. Journal of Pharmacokinetics and Biopharmaceutics 8:553-571.
    • (1980) Journal of Pharmacokinetics and Biopharmaceutics , vol.8 , pp. 553-571
    • Sheiner, L.B.1    Beal, S.2
  • 43
    • 0025334855 scopus 로고
    • Hepadnavirus envelope proteins regulate covalently closed circular DNA amplification
    • Summers J, Smith PM & Horwich AL (1990). Hepadnavirus envelope proteins regulate covalently closed circular DNA amplification. Journal of Virology 64:2819-2824.
    • (1990) Journal of Virology , vol.64 , pp. 2819-2824
    • Summers, J.1    Smith, P.M.2    Horwich, A.L.3
  • 46
    • 0033029334 scopus 로고    scopus 로고
    • Biphasic clearance kinetics of hepatitis B virus from patients during adefovir dipivoxil therapy
    • Tsiang M, Rooney JF, Toole JJ & Gibbs CS (1999). Biphasic clearance kinetics of hepatitis B virus from patients during adefovir dipivoxil therapy. Hepatology 24:1863-1869.
    • (1999) Hepatology , vol.24 , pp. 1863-1869
    • Tsiang, M.1    Rooney, J.F.2    Toole, J.J.3    Gibbs, C.S.4
  • 47
    • 0028784648 scopus 로고
    • A general conceptual model for non-steady state pharmacokinetic/ pharmacodynamic data
    • Verotta D & Sheiner LB (1995). A general conceptual model for non-steady state pharmacokinetic/pharmacodynamic data. Journal of Pharmacokinetics and Biopharmaceutics 23:1-4.
    • (1995) Journal of Pharmacokinetics and Biopharmaceutics , vol.23 , pp. 1-4
    • Verotta, D.1    Sheiner, L.B.2
  • 48
    • 0014318562 scopus 로고
    • Kinetics of pharmacological response 1. Proposed relationships between response and drug concentration in the intact animal and man
    • Wagner JG (1968). Kinetics of pharmacological response 1. Proposed relationships between response and drug concentration in the intact animal and man. Journal of Theoretical Biology 20:173-201.
    • (1968) Journal of Theoretical Biology , vol.20 , pp. 173-201
    • Wagner, J.G.1
  • 50
    • 3042631429 scopus 로고    scopus 로고
    • Utility of kenetic, dynamic, and metabolic data in monoclonal pharmacology/toxicology studies
    • Edited by A Yacobi, JP Skelley, VP Shah & LZ Benet. New York & London: Plenum
    • Weissinger J (1998). Utility of kenetic, dynamic, and metabolic data in monoclonal pharmacology/toxicology studies. In: Integration of pharmacokinetics, pharmodynamics, and toxicokinetics in rational drug development, pp. 15-22. Edited by A Yacobi, JP Skelley, VP Shah & LZ Benet. New York & London: Plenum.
    • (1998) Integration of Pharmacokinetics, Pharmodynamics, and Toxicokinetics in Rational Drug Development , pp. 15-22
    • Weissinger, J.1


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