-
1
-
-
0029912274
-
Mechanisms of nucleoside analog antiviral activity and resistance during human immunodeficiency virus reverse transcription
-
Arts, E. J., and Wainberg, M. A. 1996. Mechanisms of nucleoside analog antiviral activity and resistance during human immunodeficiency virus reverse transcription. Antimicrob. Agents Chemother. 40:527-540.
-
(1996)
Antimicrob. Agents Chemother.
, vol.40
, pp. 527-540
-
-
Arts, E.J.1
Wainberg, M.A.2
-
2
-
-
0026740310
-
Cellular metabolism of (-) enantiomeric 2′-deoxy-3′-thiacytidine
-
Cammack, N., P. Rouse, C. L. P. Marr, P. J. Reid, R. E. Boehme, J. A. V. Coates, C. R. Penn, and J. M. Cameron. 1992. Cellular metabolism of (-) enantiomeric 2′-deoxy-3′-thiacytidine. Biochem. Pharmacol. 43:2059-2064.
-
(1992)
Biochem. Pharmacol.
, vol.43
, pp. 2059-2064
-
-
Cammack, N.1
Rouse, P.2
Marr, C.L.P.3
Reid, P.J.4
Boehme, R.E.5
Coates, J.A.V.6
Penn, C.R.7
Cameron, J.M.8
-
3
-
-
0026697262
-
Deoxycytidine deaminase-resistant stereoisomer is the active form of (±)-2′,3′-dideoxy-3′-thiacytidine in the inhibition of hepatitis B virus replication
-
Chang, C. N., S. L. Doong, J. H. Zhou, J. W. Beach, L. S. Jeong, C. K. Chu, C. H. Tsai, R. F. Schinazi, D. C. Liotta, and Y. C. Cheng. 1992. Deoxycytidine deaminase-resistant stereoisomer is the active form of (±)-2′,3′-dideoxy-3′-thiacytidine in the inhibition of hepatitis B virus replication. J. Biol. Chem. 267:13938-13942.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 13938-13942
-
-
Chang, C.N.1
Doong, S.L.2
Zhou, J.H.3
Beach, J.W.4
Jeong, L.S.5
Chu, C.K.6
Tsai, C.H.7
Schinazi, R.F.8
Liotta, D.C.9
Cheng, Y.C.10
-
4
-
-
0028102990
-
Evidence that hepatocyte turnover is required for rapid clearance of duck hepatitis B virus during antiviral therapy of chronically infected ducks
-
Fourel, I., J. M. Cullen, J. Saputelli, C. E. Aldrich, P. Schaffer, D. R. Averett, J. Pugh, and W. S. Mason. 1994. Evidence that hepatocyte turnover is required for rapid clearance of duck hepatitis B virus during antiviral therapy of chronically infected ducks. J. Virol. 68:8321-8330.
-
(1994)
J. Virol.
, vol.68
, pp. 8321-8330
-
-
Fourel, I.1
Cullen, J.M.2
Saputelli, J.3
Aldrich, C.E.4
Schaffer, P.5
Averett, D.R.6
Pugh, J.7
Mason, W.S.8
-
5
-
-
0003571287
-
-
Swedish Pharmaceutical Press, Stockholm, Sweden
-
Gabrielsson, J., and D. Weiner. 1994. Pharmacokinetic and pharmacodynamic data analysis. Concepts and applications, p. 423-433. Swedish Pharmaceutical Press, Stockholm, Sweden.
-
(1994)
Pharmacokinetic and Pharmacodynamic Data Analysis. Concepts and Applications
, pp. 423-433
-
-
Gabrielsson, J.1
Weiner, D.2
-
6
-
-
0004061014
-
-
Marcel Dekker, Inc., New York, N.Y.
-
Gibaldi, M., and D. Perrier. 1982. Pharmacokinetics, 2nd ed., p. 113-144. Marcel Dekker, Inc., New York, N.Y.
-
(1982)
Pharmacokinetics, 2nd Ed.
, pp. 113-144
-
-
Gibaldi, M.1
Perrier, D.2
-
7
-
-
0028863273
-
Hepatitis B reactivation after lamivudine
-
Honkoop, P., R. A. de Man, R. A. Heijtink, and S. W. Schalm. 1995. Hepatitis B reactivation after lamivudine. Lancet 346:1156-1157.
-
(1995)
Lancet
, vol.346
, pp. 1156-1157
-
-
Honkoop, P.1
De Man, R.A.2
Heijtink, R.A.3
Schalm, S.W.4
-
8
-
-
4243580171
-
Comparison of the viral pnarmacodynamics of 3TC in chronically infected woodchucks and humans
-
Abstract 38
-
Hurwitz, S. J., B. Tennant, B. E. Korba, and R. F. Schinazi. 1997. Comparison of the viral pnarmacodynamics of 3TC in chronically infected woodchucks and humans. Antivir. Res. 34:A53. (Abstract 38.)
-
(1997)
Antivir. Res.
, vol.34
-
-
Hurwitz, S.J.1
Tennant, B.2
Korba, B.E.3
Schinazi, R.F.4
-
9
-
-
0027941175
-
Woodchuck hepatitis virus infections: Very rapid recovery after a prolonged viremia and infection of virtually every hepatocyte
-
Kajino, K., A. R. Jilbert, J. Saputelli, C. E. Aldrich, J. Cullen, and W. S. Mason. 1994. Woodchuck hepatitis virus infections: very rapid recovery after a prolonged viremia and infection of virtually every hepatocyte. J. Virol. 68: 5792-5803.
-
(1994)
J. Virol.
, vol.68
, pp. 5792-5803
-
-
Kajino, K.1
Jilbert, A.R.2
Saputelli, J.3
Aldrich, C.E.4
Cullen, J.5
Mason, W.S.6
-
10
-
-
0030001773
-
Liver targeted antiviral nucleosides: Enhanced antiviral activity of phosphatidyl-dideoxyguanosine versus didcoxyguanosine in woodchuck hepatitis in vivo
-
Korba, B. E., H. Xie, K. N. Wright, W. E. Hornbuckle, J. L. Gerin, B. C. Tennant, and K. Y. Hostetler. 1996. Liver targeted antiviral nucleosides: enhanced antiviral activity of phosphatidyl-dideoxyguanosine versus didcoxyguanosine in woodchuck hepatitis in vivo. Hepatology 23:958-963.
-
(1996)
Hepatology
, vol.23
, pp. 958-963
-
-
Korba, B.E.1
Xie, H.2
Wright, K.N.3
Hornbuckle, W.E.4
Gerin, J.L.5
Tennant, B.C.6
Hostetler, K.Y.7
-
11
-
-
0023215276
-
Lymphoid cells in the spleens of woodchuck hepatitis virus-infected woodchucks are a site of active viral replication
-
Korba, B. E., F. Wells, B. C. Tennant, P. J. Cote, and J. L. Gerin. 1987. Lymphoid cells in the spleens of woodchuck hepatitis virus-infected woodchucks are a site of active viral replication. J. Virol. 61:1318-1324.
-
(1987)
J. Virol.
, vol.61
, pp. 1318-1324
-
-
Korba, B.E.1
Wells, F.2
Tennant, B.C.3
Cote, P.J.4
Gerin, J.L.5
-
12
-
-
0345227367
-
-
Personal communication
-
11a. Locarnini, S. A. Personal communication.
-
-
-
Locarnini, S.A.1
-
13
-
-
0024520582
-
Experimental systems for the study of hepadnavirus and delta virus infections
-
Mason, W. S., and J. M. Taylor. 1989. Experimental systems for the study of hepadnavirus and delta virus infections. Hepatology 9:635-645.
-
(1989)
Hepatology
, vol.9
, pp. 635-645
-
-
Mason, W.S.1
Taylor, J.M.2
-
14
-
-
0345227366
-
Antiviral therapy for chronic hepadnavirus infections
-
Mason, W. W., D. Averett, J. Pugh, K. Kajino, J. Cullen, I. Fourel, and A. Jilbert. 1996. Antiviral therapy for chronic hepadnavirus infections. Antivir. Ther. 1(Suppl. 4):53-58.
-
(1996)
Antivir. Ther.
, vol.1
, Issue.4 SUPPL.
, pp. 53-58
-
-
Mason, W.W.1
Averett, D.2
Pugh, J.3
Kajino, K.4
Cullen, J.5
Fourel, I.6
Jilbert, A.7
-
15
-
-
0029900659
-
Pharmacokinetics of lamivudine administered alone and with trimethoprim-sulfamethoxazole
-
Moore, K. H. P., G. J. Yuen, R. H. Raasch, J. J. Eron, D. Martin, P. K. Mydlow, and E. K. Hussey. 1996. Pharmacokinetics of lamivudine administered alone and with trimethoprim-sulfamethoxazole. Clin. Pharmacol. Ther. 59:550-558.
-
(1996)
Clin. Pharmacol. Ther.
, vol.59
, pp. 550-558
-
-
Moore, K.H.P.1
Yuen, G.J.2
Raasch, R.H.3
Eron, J.J.4
Martin, D.5
Mydlow, P.K.6
Hussey, E.K.7
-
16
-
-
0029037074
-
The covalently closed duplex form of the hepadnavirus genome exists in situ as a heterogeneous population of viral minichromosomes
-
Newbold, J. E., H. Xin, M. Tencza, G. Sherman, J. Dean, S. Bowden, and S. Locarnini. 1995. The covalently closed duplex form of the hepadnavirus genome exists in situ as a heterogeneous population of viral minichromosomes. J. Virol. 69:3350-3357.
-
(1995)
J. Virol.
, vol.69
, pp. 3350-3357
-
-
Newbold, J.E.1
Xin, H.2
Tencza, M.3
Sherman, G.4
Dean, J.5
Bowden, S.6
Locarnini, S.7
-
17
-
-
0004837384
-
-
Prentice-Hall Applied Math Series. Prentice-Hall International, Inc., London, England
-
Nixon, F. E. 1965. Handbook of Laplace transformation. Fundamentals and application, tables and examples, 2nd ed. Prentice-Hall Applied Math Series. Prentice-Hall International, Inc., London, England.
-
(1965)
Handbook of Laplace Transformation. Fundamentals and Application, Tables and Examples, 2nd Ed.
-
-
Nixon, F.E.1
-
18
-
-
0029994971
-
Viral dynamics in hepatitis B virus infection
-
Nowak, M. A., S. Bonhoeffer, A. M. Hill, R. Boehme, H. C. Thomas, and H. McDade. 1996. Viral dynamics in hepatitis B virus infection. Proc. Natl. Acad. Sci. USA 93:4398-4402.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 4398-4402
-
-
Nowak, M.A.1
Bonhoeffer, S.2
Hill, A.M.3
Boehme, R.4
Thomas, H.C.5
McDade, H.6
-
19
-
-
0030026113
-
Reduction of HIV concentration during acute infection: Independence from a specific immune response
-
Phillips, A. N. 1996. Reduction of HIV concentration during acute infection: independence from a specific immune response. Science 271:497-499.
-
(1996)
Science
, vol.271
, pp. 497-499
-
-
Phillips, A.N.1
-
20
-
-
0030050719
-
Pharmacokinetics of (-)-2′-3′-dideoxy-3′-thiacytidine in woodchucks
-
Rajagopalan, P., F. D. Boudinot, C. K. Chu, B. C. Tennant, B. H. Baldwin, and R. F. Schinazi. 1996. Pharmacokinetics of (-)-2′-3′-dideoxy-3′-thiacytidine in woodchucks. Antimicrob. Agents Chemother. 40:642-645.
-
(1996)
Antimicrob. Agents Chemother.
, vol.40
, pp. 642-645
-
-
Rajagopalan, P.1
Boudinot, F.D.2
Chu, C.K.3
Tennant, B.C.4
Baldwin, B.H.5
Schinazi, R.F.6
-
21
-
-
0346197848
-
DUD, a derivative-free algorithm for nonlinear least squares
-
Ralston, M. L., and R. I. Jennrich. 1978. DUD, a derivative-free algorithm for nonlinear least squares. Technomerics 20:7-14.
-
(1978)
Technomerics
, vol.20
, pp. 7-14
-
-
Ralston, M.L.1
Jennrich, R.I.2
-
22
-
-
0027986684
-
State of the p53 gene in hepatocellular carcinomas of ground squirrels and woodchucks with past and ongoing infection with hepadnaviruses
-
Rivkin, M. B., J. M. Cullen, W. S. Robinson, and P. L. Marion. 1994. State of the p53 gene in hepatocellular carcinomas of ground squirrels and woodchucks with past and ongoing infection with hepadnaviruses. Cancer Res. 54: 5430-5437.
-
(1994)
Cancer Res.
, vol.54
, pp. 5430-5437
-
-
Rivkin, M.B.1
Cullen, J.M.2
Robinson, W.S.3
Marion, P.L.4
-
23
-
-
0028809476
-
The woodchuck: An animal model for hepatitis B virus infection in man
-
Roggendorf, M., and T. K. Tolle. 1995. The woodchuck: an animal model for hepatitis B virus infection in man. Intervirology 38:100-112.
-
(1995)
Intervirology
, vol.38
, pp. 100-112
-
-
Roggendorf, M.1
Tolle, T.K.2
-
24
-
-
0022085841
-
Chronic hepatitis and hepatocellular carcinoma associated with persistent woodchuck hepatitis virus infection
-
Roth, L., J. M. King, W. E. Hornbuckle, H. J. Harvey, and B. C. Tennant. 1985. Chronic hepatitis and hepatocellular carcinoma associated with persistent woodchuck hepatitis virus infection. Vet. Pathol. 22:338-343.
-
(1985)
Vet. Pathol.
, vol.22
, pp. 338-343
-
-
Roth, L.1
King, J.M.2
Hornbuckle, W.E.3
Harvey, H.J.4
Tennant, B.C.5
-
25
-
-
0000956846
-
The NLIN procedure
-
GLM-VARCOMP, version 6, 4th ed. SAS Institute, Inc., Cary, N.C.
-
SAS Institute Inc. 1990. The NLIN procedure, p. 1135-1193. In SAS/STAT users guide, vol. 2, GLM-VARCOMP, version 6, 4th ed. SAS Institute, Inc., Cary, N.C.
-
(1990)
SAS/STAT Users Guide
, vol.2
, pp. 1135-1193
-
-
-
26
-
-
0008700020
-
Impact of nucleosides on hepatitis viruses
-
M. Rizzeto, R. H. Purcell, J. L. Gerin, and G. Verme (ed.), Edizioni Minerva Medica, Turin, Italy
-
Schinazi, R. F. 1997. Impact of nucleosides on hepatitis viruses, p. 736-742. In M. Rizzeto, R. H. Purcell, J. L. Gerin, and G. Verme (ed.), Viral hepatitis and liver disease. Edizioni Minerva Medica, Turin, Italy.
-
(1997)
Viral Hepatitis and Liver Disease
, pp. 736-742
-
-
Schinazi, R.F.1
-
27
-
-
0005899598
-
Comparative activation of 2′-deoxycytidine and antiviral oxathiolane cytosine nucleosides by different mammalian liver extracts
-
Abstract 84
-
Schinazi, R. F., L. Hough, A. Juodawlkis, P. Marion, and B. Tennant. 1997. Comparative activation of 2′-deoxycytidine and antiviral oxathiolane cytosine nucleosides by different mammalian liver extracts. Antivir. Res. 34:a65. (Abstract 84.)
-
(1997)
Antivir. Res.
, vol.34
-
-
Schinazi, R.F.1
Hough, L.2
Juodawlkis, A.3
Marion, P.4
Tennant, B.5
-
29
-
-
0025966721
-
Woodchuck hepatitis virus is a more efficient oncogenic agent than ground squirrel hepatitis virus in a common host
-
Seeger, C., B. Baldwin, W. E. Hornbuckle, A. E. Yeager, B. C. Tennant, P. Cote, L. Ferrell, D. Ganem, and H. E. Varmus. 1991. Woodchuck hepatitis virus is a more efficient oncogenic agent than ground squirrel hepatitis virus in a common host. J. Virol. 65:1673-1679.
-
(1991)
J. Virol.
, vol.65
, pp. 1673-1679
-
-
Seeger, C.1
Baldwin, B.2
Hornbuckle, W.E.3
Yeager, A.E.4
Tennant, B.C.5
Cote, P.6
Ferrell, L.7
Ganem, D.8
Varmus, H.E.9
-
30
-
-
0029047348
-
Hepatic purine and pyrimidine metabolism: Implications for antiviral chemotherapy of viral hepatitis
-
Shaw, T., and S. A. Locarnini. 1995. Hepatic purine and pyrimidine metabolism: implications for antiviral chemotherapy of viral hepatitis. Liver 15: 169-184.
-
(1995)
Liver
, vol.15
, pp. 169-184
-
-
Shaw, T.1
Locarnini, S.A.2
-
31
-
-
0027417199
-
Affinity of the antiviral enantiomers of oxathiolane cytosine nucleosides for human 2′-deoxycytidine kinase
-
Shewach, D. S., D. C. Liotta, and R. F. Schinazi. 1993. Affinity of the antiviral enantiomers of oxathiolane cytosine nucleosides for human 2′-deoxycytidine kinase. Biochem. Pharmacol. 45:1540-1543.
-
(1993)
Biochem. Pharmacol.
, vol.45
, pp. 1540-1543
-
-
Shewach, D.S.1
Liotta, D.C.2
Schinazi, R.F.3
-
32
-
-
0025334855
-
Hepadnavirus envelope proteins regulate covalently closed circular DNA amplification
-
Summers, J., P. M. Smith, and A. L. Horwich. 1990. Hepadnavirus envelope proteins regulate covalently closed circular DNA amplification. J. Virol. 64: 2819-2824.
-
(1990)
J. Virol.
, vol.64
, pp. 2819-2824
-
-
Summers, J.1
Smith, P.M.2
Horwich, A.L.3
-
33
-
-
0023727620
-
Inhibition of duck hepatitis B virus replication by purine 2′,3′-dideoxy nucleosides
-
Suzuki, S., B. Lee, W. Luo, D. Tovell, M. J. Robins, and L. J. Tyrell. 1988. Inhibition of duck hepatitis B virus replication by purine 2′,3′-dideoxy nucleosides. Biochem. Biophys. Res. Commun. 156:1144-1151.
-
(1988)
Biochem. Biophys. Res. Commun.
, vol.156
, pp. 1144-1151
-
-
Suzuki, S.1
Lee, B.2
Luo, W.3
Tovell, D.4
Robins, M.J.5
Tyrell, L.J.6
-
34
-
-
17344366353
-
Antiviral activity and toxicity of fialuridine in the woodchuck model of hepatitis B virus infection
-
in press
-
Tennant, B. C., B. H. Baldwin, L. A. Graham, M. A. Ascenzi, W. E. Hornbuckle, P. H. Rowland, I. A. Tochkov, A. E. Yeager, H. N. Erb, J. M. Colacino, C. Lopez, J. A. Engelhardt, R. R. Bowsher, F. C. Richardson, W. Lewis, P. J. Cote, B. E. Korba, and J. L. Gerin. Antiviral activity and toxicity of fialuridine in the woodchuck model of hepatitis B virus infection. Hepatology, in press.
-
Hepatology
-
-
Tennant, B.C.1
Baldwin, B.H.2
Graham, L.A.3
Ascenzi, M.A.4
Hornbuckle, W.E.5
Rowland, P.H.6
Tochkov, I.A.7
Yeager, A.E.8
Erb, H.N.9
Colacino, J.M.10
Lopez, C.11
Engelhardt, J.A.12
Bowsher, R.R.13
Richardson, F.C.14
Lewis, W.15
Cote, P.J.16
Korba, B.E.17
Gerin, J.L.18
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