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Volumn 24, Issue 16, 2004, Pages 7024-7031

Expression of telomerase RNA template, but not telomerase reverse transcriptase, is limiting for telomere length maintenance in vivo

Author keywords

[No Author keywords available]

Indexed keywords

RNA; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE;

EID: 3543010768     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.24.16.7024-7031.2004     Document Type: Article
Times cited : (104)

References (37)
  • 2
    • 0035929353 scopus 로고    scopus 로고
    • Switching and signaling at the telomere
    • Blackburn, E. H. 2001. Switching and signaling at the telomere. Cell 106:661-673.
    • (2001) Cell , vol.106 , pp. 661-673
    • Blackburn, E.H.1
  • 4
    • 0029154735 scopus 로고
    • Functional characterization and developmental regulation of mouse telomerase RNA
    • Blasco, M. A., W. Funk, B. Villeponteau, and C. W. Greider. 1995. Functional characterization and developmental regulation of mouse telomerase RNA. Science 269:1267-1270.
    • (1995) Science , vol.269 , pp. 1267-1270
    • Blasco, M.A.1    Funk, W.2    Villeponteau, B.3    Greider, C.W.4
  • 7
    • 0033152429 scopus 로고    scopus 로고
    • Telomerase and the maintenance of chromosome ends
    • Bryan, T. M., and T. R. Cech. 1999. Telomerase and the maintenance of chromosome ends. Curr. Opin. Cell Biol. 11:318-324.
    • (1999) Curr. Opin. Cell Biol. , vol.11 , pp. 318-324
    • Bryan, T.M.1    Cech, T.R.2
  • 8
    • 0024564718 scopus 로고
    • The new mouse genetics: Altering the genome by gene targeting
    • Capecchi, M. R. 1989. The new mouse genetics: altering the genome by gene targeting. Trends Genet. 5:70-76.
    • (1989) Trends Genet. , vol.5 , pp. 70-76
    • Capecchi, M.R.1
  • 9
    • 0027973651 scopus 로고
    • Chromosome end games
    • Cech, T. R. 1994. Chromosome end games. Science 266:387-388.
    • (1994) Science , vol.266 , pp. 387-388
    • Cech, T.R.1
  • 12
    • 1942437469 scopus 로고    scopus 로고
    • Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice
    • Erdmann, N., Y. Liu, and L. Harrington. 2004. Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice. Proc. Natl. Acad. Sci. USA 101:6080-6085.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 6080-6085
    • Erdmann, N.1    Liu, Y.2    Harrington, L.3
  • 13
    • 0036787840 scopus 로고    scopus 로고
    • Cooperation between p53 mutation and high telomerase transgenic expression in spontaneous cancer development
    • González-Suárez, E., J. M. Flores, and M. A. Blasco. 2002. Cooperation between p53 mutation and high telomerase transgenic expression in spontaneous cancer development. Mol. Cell. Biol. 22:7291-7301.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 7291-7301
    • González-Suárez, E.1    Flores, J.M.2    Blasco, M.A.3
  • 14
    • 0035355340 scopus 로고    scopus 로고
    • Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes
    • Gonzalez-Suarez, E., E. Samper, A. Ramirez, J. M. Flores, J. Martin-Caballero, J. L. Jorcano, and M. A. Blasco. 2001. Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes. EMBO J. 20:2619-2630.
    • (2001) EMBO J. , vol.20 , pp. 2619-2630
    • Gonzalez-Suarez, E.1    Samper, E.2    Ramirez, A.3    Flores, J.M.4    Martin-Caballero, J.5    Jorcano, J.L.6    Blasco, M.A.7
  • 15
    • 0029894237 scopus 로고    scopus 로고
    • Telomere length regulation
    • Greider, C. W. 1996. Telomere length regulation. Annu. Rev. Biochem. 65:337-365.
    • (1996) Annu. Rev. Biochem. , vol.65 , pp. 337-365
    • Greider, C.W.1
  • 17
    • 0025279931 scopus 로고
    • Telomeres shorten during ageing of human fibroblasts
    • Harley, C. B., A. B. Futcher, and C. W. Greider. 1990. Telomeres shorten during ageing of human fibroblasts. Nature 345:458-460.
    • (1990) Nature , vol.345 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 22
    • 0032055375 scopus 로고    scopus 로고
    • Telomerase and chromosome end maintenance
    • Lingner, J., and T. R. Cech. 1998. Telomerase and chromosome end maintenance. Curr. Opin. Genet. Dev. 8:226-232.
    • (1998) Curr. Opin. Genet. Dev. , vol.8 , pp. 226-232
    • Lingner, J.1    Cech, T.R.2
  • 23
    • 0037133668 scopus 로고    scopus 로고
    • Preferential maintenance of critically short telomeres in mammalian cells heterozygous for mTert
    • Liu, Y., H. Kha, M. Ungrin, M. O. Robinson, and L. Harrington. 2002. Preferential maintenance of critically short telomeres in mammalian cells heterozygous for mTert. Proc. Natl. Acad. Sci. USA 99:3597-3602.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 3597-3602
    • Liu, Y.1    Kha, H.2    Ungrin, M.3    Robinson, M.O.4    Harrington, L.5
  • 25
    • 0033518188 scopus 로고    scopus 로고
    • A telomerase component is defective in the human disease dyskeratosis congenita
    • Mitchell, J. R., E. Wood, and K. Collins. 1999. A telomerase component is defective in the human disease dyskeratosis congenita. Nature 402:551-555.
    • (1999) Nature , vol.402 , pp. 551-555
    • Mitchell, J.R.1    Wood, E.2    Collins, K.3
  • 29
    • 0037148276 scopus 로고    scopus 로고
    • Senescence: Does it all happen at the ends?
    • Stewart, S. A., and R. A. Weinberg. 2002. Senescence: does it all happen at the ends? Oncogene 21:627-630.
    • (2002) Oncogene , vol.21 , pp. 627-630
    • Stewart, S.A.1    Weinberg, R.A.2
  • 30
    • 0037457985 scopus 로고    scopus 로고
    • Mutations linked to dyskeratosis congenita cause changes in the structural equilibrium in telomerase RNA
    • Theimer, C. A., L. D. Finger, L. Trantirek, and J. Feigon. 2003. Mutations linked to dyskeratosis congenita cause changes in the structural equilibrium in telomerase RNA. Proc. Natl. Acad. Sci. USA 100:449-454.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 449-454
    • Theimer, C.A.1    Finger, L.D.2    Trantirek, L.3    Feigon, J.4
  • 31
    • 0035960043 scopus 로고    scopus 로고
    • The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita
    • Vulliamy, T., A. Marrone, F. Goldman, A. Dearlove, M. Bessler, P. J. Mason, and I. Dokal. 2001. The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita. Nature 413:432-435.
    • (2001) Nature , vol.413 , pp. 432-435
    • Vulliamy, T.1    Marrone, A.2    Goldman, F.3    Dearlove, A.4    Bessler, M.5    Mason, P.J.6    Dokal, I.7
  • 32
    • 0034966374 scopus 로고    scopus 로고
    • Very short telomeres in the peripheral blood of patients with X-linked and autosomal dyskeratosis congenita
    • Vulliamy, T. J., S. W. Knight, P. J. Mason, and I. Dokal. 2001. Very short telomeres in the peripheral blood of patients with X-linked and autosomal dyskeratosis congenita. Blood Cells Mol. Dis. 27:353-357.
    • (2001) Blood Cells Mol. Dis. , vol.27 , pp. 353-357
    • Vulliamy, T.J.1    Knight, S.W.2    Mason, P.J.3    Dokal, I.4
  • 33
    • 0031801205 scopus 로고    scopus 로고
    • Reconstitution of wild-type or mutant telomerase activity in telomerase-negative immortal human cells
    • Wen, J., Y. S. Cong, and S. Bacchetti. 1998. Reconstitution of wild-type or mutant telomerase activity in telomerase-negative immortal human cells. Hum. Mol. Genet. 7:1137-1141.
    • (1998) Hum. Mol. Genet. , vol.7 , pp. 1137-1141
    • Wen, J.1    Cong, Y.S.2    Bacchetti, S.3
  • 34
    • 0033854052 scopus 로고    scopus 로고
    • The role of telomerase expression and telomere length maintenance in human and mouse
    • Weng, N. P., and R. J. Hodes. 2000. The role of telomerase expression and telomere length maintenance in human and mouse. J. Clin. Immunol. 20:257-267.
    • (2000) J. Clin. Immunol. , vol.20 , pp. 257-267
    • Weng, N.P.1    Hodes, R.J.2
  • 36
    • 0034925471 scopus 로고    scopus 로고
    • Reconstituting telomerase activity using the telomerase catalytic subunit prevents the telomere shorting and replicative senescence in human osteoblasts
    • Yudoh, K., H. Matsuno, F. Nakazawa, R. Katayama, and T. Kimura. 2001. Reconstituting telomerase activity using the telomerase catalytic subunit prevents the telomere shorting and replicative senescence in human osteoblasts. J. Bone Miner. Res. 16:1453-1464.
    • (2001) J. Bone Miner. Res. , vol.16 , pp. 1453-1464
    • Yudoh, K.1    Matsuno, H.2    Nakazawa, F.3    Katayama, R.4    Kimura, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.