Mechanism of activation of a G protein-coupled receptor, the human cholecystokinin-2 receptor

Journal of Biological Chemistry

Volumn 282, Issue 39, 2007, Pages 28779-28790

  Marco, Esther ^b   Foucaud, Magali ^b   Langer, Ingrid ^b   Escrieut, Chantal ^b   Tikhonova, Irina G ^b   Fourmy, Daniel ^a  

^a IFR 31   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BINDING SITES; DRUG PRODUCTS; LIGANDS; LIPID BILAYERS; MOLECULAR DYNAMICS;

CRYSTAL COORDINATES; MUTANTS; RHODOPSIN; TARGET-BASED OPTIMIZATION;

PROTEINS;

CHOLECYSTOKININ B RECEPTOR; G PROTEIN COUPLED RECEPTOR;

ANIMAL CELL; ARTICLE; CRYSTAL STRUCTURE; GENETIC TRANSFECTION; LIPID BILAYER; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS;

AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; CERCOPITHECUS AETHIOPS; CHOLECYSTOKININ; COMPUTER SIMULATION; COS CELLS; DRUG DESIGN; GENOMICS; HUMANS; LIPID BILAYERS; MODELS, MOLECULAR; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, CHOLECYSTOKININ B; RHODOPSIN; STRUCTURAL HOMOLOGY, PROTEIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 35348983347     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M700349200     Document Type: Article

References (49)

1. Lefkowitz, R. J., Cotecchia, S., Samama, P., and Costa, T. (1993) Trends Pharmacol. Sci. 14, 303-307
2. Bond, R. A., and Ijzerman, A. P. (2006) Trends Pharmacol. Sci. 27, 92-96
3. Kenakin, T. (1995) Trends Pharmacol. Sci. 16, 256-258
4. Dufresne, M., Seva, C., and Fourmy, D. (2006) Physiol. Rev. 86, 805-847
5. Kopin, A. S., Lee, Y. M., McBride, E. W., Miller, L. J., Lu, M., Lin, H. Y., Kolakowski, L. F., Jr., and Beinborn, M. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 3605-3609
6. Wank, S. A., Pisegna, J. R., and de Weerth, A. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 8691-8695
7. Noble, F., Wank, S. A., Crawley, J. N., Bradwejn, J., Seroogy, K. B., Hamon, M., and Roques, B. P. (1999) Pharmacol. Rev. 51, 745-781
8. Ding, W. Q., Kuntz, S. M., and Miller, L. J. (2002) Cancer Res. 62, 947-952
9. Hellmich, M. R., Rui, X. L., Hellmich, H. L., Fleming, R. Y., Evers, B. M., and Townsend, C. M., Jr. (2000) J. Biol. Chem. 275, 32122-32128
10. Herranz, R. (2003) Med. Res. Rev. 23, 559-605
11. Blevins, G. T., Jr., van de Westerlo, E. M., Yule, D. I., and Williams, J. A. (1994) J. Pharmacol. Exp. Ther. 269, 911-916
12. Schmassmann, A., Garner, A., Flogerzi, B., Hasan, M. Y., Sanner, M., Varga, L., and Halter, F. (1994) Gut 35, 270-274
13. Kopin, A. S., McBride, E. W., Schaffer, K., and Beinborn, M. (2000) Trends Pharmacol. Sci. 21, 346-353
14. Reubi, J. C. (2003) Endocr. Rev. 24, 389-427
15. Gales, C., Poirot, M., Taillefer, J., Maigret, B., Martinez, J., Moroder, L., Escrieut, C., Pradayrol, L., Fourmy, D., and Silvente-Poirot, S. (2003) Mol. Pharmacol. 63, 973-982
16. Langer, I., Tikhonova, I. G., Travers, M. A., Archer-Lahlou, E., Escrieut, C., Maigret, B., and Fourmy, D. (2005) J. Biol. Chem. 280, 22198-22204
17. Silvente-Poirot, S., Escrieut, C., Gales, C., Fehrentz, J. A., Escherich, A., Wank, S. A., Martinez, J., Moroder, L., Maigret, B., Bouisson, M., Vaysse, N., and Fourmy, D. (1999) J. Biol. Chem. 274, 23191-23197
18. Foucaud, M., Tikhonova, I. G., Langer, I., Escrieut, C., Dufresne, M., Seva, C., Maigret, B., and Fourmy, D. (2006) Mol. Pharmacol. 69, 680-690
19. Palczewski, K., Kumasaka, T., Hori, T., Behnke, C. A., Motoshima, H., Fox, B. A., Le Trong, I., Teller, D. C., Okada, T., Stenkamp, R. E., Yamamoto, M., and Miyano, M. (2000) Science 289, 739-745
20. Thompson, J. D., Higgins, D. G., and Gibson, T. J. (1994) Nucleic Acids Res. 22, 4673-4680
21. Fiser, A., Do, R. K., and Sali, A. (2000) Protein Sci. 9, 1753-1773
22. Lin, S. W., and Sakmar, T. P. (1996) Biochemistry 35, 11149-11159
23. Crocker, E., Eilers, M., Ahuja, S., Hornak, V., Hirshfeld, A., Sheves, M., and Smith, S. O. (2006) J. Mol. Biol. 357, 163-172
24. Blaker, M., Ren, Y., Seshadri, L., McBride, E. W., Beinborn, M., and Kopin, A. S. (2000) Mol. Pharmacol. 58, 399-406
25. Kopin, A. S., McBride, E. W., Quinn, S. M., Kolakowski, L. F., Jr., and Beinborn, M. (1995) J. Biol. Chem. 270, 5019-5023
26. Gales, C., Sanchez, D., Poirot, M., Pyronnet, S., Buscail, L., Cussac, D., Pradayrol, L., Fourmy, D., and Silvente-Poirot, S. (2003) Oncogene 22, 6081-6089
27. Compoint, M., Picaud, F., Ramseyer, C., and Girardet, C. (2005) J. Chem Phys. 122, 134707-134715
28. Gether, U. (2000) Endocr. Rev. 21, 90-113
29. Ballesteros, J. A., Shi, L., and Javitch, J. A. (2001) Mol. Pharmacol. 60, 1-19
30. Schwartz, T. W., Frimurer, T. M., Holst, B., Rosenkilde, M. M., and Elling, C. E. (2006) Annu. Rev. Pharmacol. Toxicol. 46, 481-519
31. Farrens, D. L., Altenbach, C., Yang, K., Hubbell, W. L., and Khorana, H. G. (1996) Science 274, 768-770
32. Sheikh, S. P., Vilardarga, J. P., Baranski, T. J., Lichtarge, O., Iiri, T., Meng, E. C., Nissenson, R. A., and Bourne, H. R. (1999) J. Biol. Chem. 274, 17033-17041
33. Elling, C. E., Frimurer, T. M., Gerlach, L. O., Jorgensen, R., Holst, B., and Schwartz, T. W. (2006) J. Biol. Chem. 281, 17337-17346
34. Gether, U., Lin, S., Ghanouni, P., Ballesteros, J. A., Weinstein, H., and Kobilka, B. K. (1997) EMBO J. 16, 6737-6747
35. Gerber, B. O., Meng, E. C., Dotsch, V., Baranski, T. J., and Bourne, H. R. (2001) J. Biol. Chem. 276, 3394-3400
36. Abdulaev, N. G., and Ridge, K. D. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 12854-12859
37. Ludeke, S., Beck, M., Yan, E. C., Sakmar, T. P., Siebert, F., and Vogel, R. (2005) J. Mol. Biol. 353, 345-356
38. Jongejan, A., Bruysters, M., Ballesteros, J. A., Haaksma, E., Bakker, R. A., Pardo, L., and Leurs, R. (2005) Nat. Chem. Biol. 1, 98-103
39. Gerlach, L. O., Skerlj, R. T., Bridger, G. J., and Schwartz, T. W. (2001) J. Biol. Chem. 276, 14153-14160
40. Boucard, A. A., Sauve, S. S., Guillemette, G., Escher, E., and Leduc, R. (2003) Biochem. J. 370, 829-838
41. Cotte, N., Balestre, M. N., Aumelas, A., Mahe, E., Phalipou, S., Morin, D., Hibert, M., Manning, M., Durroux, T., Barberis, C., and Mouillac, B. (2000) Eur. J. Biochem. 267, 4253-4263
42. Haskell-Luevano, C., Cone, R. D., Monck, E. K., and Wan, Y. P. (2001) Biochemistry 40, 6164-6179
43. Salom, D., Lodowski, D. T., Stenkamp, R. E., Le Trong, I., Golczak, M., Jastrzebska, B., Harris, T., Ballesteros, J. A., and Palczewski, K. (2006) Proc. Natl. Acad. Sci. U. S. A. 103, 16123-16128
44. Beinborn, M., Ren, Y., Blaker, M., Chen, C., and Kopin, A. S. (2004) Mol. Pharmacol. 65, 753-760
45. Matrai, J., Verheyden, G., Kruger, P., and Engelborghs, Y. (2004) Protein Sci. 13, 3139-3150
46. Rodriguez-Barrios, F., Balzarini, J., and Gago, F. (2005) J. Am. Chem. Soc. 127, 7570-7578
47. Meng, E. C., and Bourne, H. R. (2001) Trends Pharmacol. Sci. 22, 587-593
48. Hubbell, W. L., Altenbach, C., Hubbell, C. M., and Khorana, H. G. (2003) Adv. Protein Chem. 63, 243-290
49. Lu, Z. L., Saldanha, J. W., and Hulme, E. C. (2002) Trends Pharmacol. Sci. 23, 140-146