Potential opportunity in the development of new therapeutic agents based on endogenous and exogenous inhibitors of the proprotein convertases

Medicinal Research Reviews

Volumn 27, Issue 5, 2007, Pages 631-648

  Bontemps, Yannick ^a,b   Scamuffa, Nathalie ^a,b   Calvo, Fabien ^a,b   Khatib, Abdel Majid ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Convertases; Drug development; Protein maturation

Indexed keywords

ALPHA 2 MACROGLOBULIN; ALPHA1 PROTEINASE INHIBITOR III; ANTHRAX TOXIN; BETA SECRETASE; CALCIUM ION; CATHEPSIN B; CATHEPSIN H; CHELATING AGENT; COPPER DERIVATIVE; DITERPENE; EGLIN C; FURIN; GAMMA SECRETASE; KETONE DERIVATIVE; OVOMUCOID; PLATELET DERIVED GROWTH FACTOR A; POLYARGININE; PROPROTEIN CONVERTASE 1; PROPROTEIN CONVERTASE 2; PROPROTEIN CONVERTASE 5; PROTEINASE INHIBITOR 8; PYRIDINE DERIVATIVE; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; SUBTILISIN; ULINASTATIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULOTROPIN C; ZINC; ZINC DERIVATIVE;

ALZHEIMER DISEASE; ATHEROSCLEROSIS; CANCER; DIABETES MELLITUS; DRUG MECHANISM; DRUG RESEARCH; ENZYME INHIBITION; HUMAN; NONHUMAN; OBESITY; PROTEIN PROCESSING; REVIEW;

HUMANS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; PROPROTEIN CONVERTASES; PROTEASE INHIBITORS;

EID: 34548019745     PISSN: 01986325     EISSN: None     Source Type: Journal    
DOI: 10.1002/med.20072     Document Type: Review

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