Projection structure of the human copper transporter CTR1 at 6-Å resolution reveals a compact trimer with a novel channel-like architecture

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 10, 2006, Pages 3627-3632

  Aller, Stephen G ^a   Unger, Vinzenz M ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cisplatin; Cryo electron crystallography; Membrane protein; Metal transport

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; HUMAN COPPER TRANSPORTER 1; ION CHANNEL; MEMBRANE PROTEIN; METAL ION; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CRYOELECTRON CRYSTALLOGRAPHY; CRYSTALLOGRAPHY; DRUG TRANSPORT; DRUG UPTAKE; ELECTRON; HUMAN; ION TRANSPORT; NONHUMAN; OPTICAL RESOLUTION; PHOSPHOLIPID BILAYER; PRIORITY JOURNAL; PROTEIN STRUCTURE;

ANTINEOPLASTIC AGENTS; BIOPHYSICS; CATION TRANSPORT PROTEINS; CISPLATIN; COPPER; CRYSTALLOGRAPHY, X-RAY; GENETIC COMPLEMENTATION TEST; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MICROSCOPY, ELECTRON; MODELS, MOLECULAR; MUTAGENESIS; PROTEIN STRUCTURE, QUATERNARY; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE;

EID: 33644867700     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0509929103     Document Type: Article

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