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Volumn 110, Issue 7, 2007, Pages 2276-2285

Transcription factor Gfi-1 induced by G-CSF is a negative regulator of CXCR4 in myeloid cells

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; GRANULOCYTE COLONY STIMULATING FACTOR; GROWTH FACTOR INDEPENDENCE 1; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 34948890061     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2007-03-081448     Document Type: Article
Times cited : (55)

References (55)
  • 1
    • 0028000668 scopus 로고
    • Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil mobilization
    • Lieschke GJ, Grail D, Hodgson G, et al. Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil mobilization. Blood. 1994;84:1737-1746.
    • (1994) Blood , vol.84 , pp. 1737-1746
    • Lieschke, G.J.1    Grail, D.2    Hodgson, G.3
  • 2
    • 0030292823 scopus 로고    scopus 로고
    • Impaired production and increased apoptosis of neutrophils in granulocyte colony-stimulating factor receptor-deficient mice
    • Liu F, Wu HY, Wesselschmidt R, Kornaga T, Link DC. Impaired production and increased apoptosis of neutrophils in granulocyte colony-stimulating factor receptor-deficient mice. Immunity. 1996;5:491-501.
    • (1996) Immunity , vol.5 , pp. 491-501
    • Liu, F.1    Wu, H.Y.2    Wesselschmidt, R.3    Kornaga, T.4    Link, D.C.5
  • 3
    • 11244312848 scopus 로고    scopus 로고
    • Novel mechanism of G-CSF refractoriness in patients with severe congenital neutropenia
    • Druhan LJ, Ai J, Massullo P, Kindwall-Keller T, Ranalli MA, Avalos BR. Novel mechanism of G-CSF refractoriness in patients with severe congenital neutropenia. Blood. 2005;105:584-591.
    • (2005) Blood , vol.105 , pp. 584-591
    • Druhan, L.J.1    Ai, J.2    Massullo, P.3    Kindwall-Keller, T.4    Ranalli, M.A.5    Avalos, B.R.6
  • 4
    • 0033575794 scopus 로고    scopus 로고
    • Novel point mutation in the extracellular domain of the granulocyte colony-stimulating factor (G-CSF) receptor in a case of severe congenital neutropenia hypo-responsive to G-CSF treatment
    • Ward AC, van Aesch YM, Gits J, et al. Novel point mutation in the extracellular domain of the granulocyte colony-stimulating factor (G-CSF) receptor in a case of severe congenital neutropenia hypo-responsive to G-CSF treatment. J Exp Med. 1999;190:497-507.
    • (1999) J Exp Med , vol.190 , pp. 497-507
    • Ward, A.C.1    van Aesch, Y.M.2    Gits, J.3
  • 5
    • 0344336022 scopus 로고
    • In vivo stimulation of granulopoiesis by recombinant human granulocyte colony-stimulating factor
    • Cohen AM, Zsebo KM, Inoue H, et al. In vivo stimulation of granulopoiesis by recombinant human granulocyte colony-stimulating factor. Proc Natl Acad Sci U S A. 1987;84:2484-2488.
    • (1987) Proc Natl Acad Sci U S A , vol.84 , pp. 2484-2488
    • Cohen, A.M.1    Zsebo, K.M.2    Inoue, H.3
  • 6
    • 0034115980 scopus 로고    scopus 로고
    • Exclusive expression of G-CSF receptor on myeloid progenitors in bone marrow CD34+ cells
    • Ebihara Y, Xu MJ, Manabe A, et al. Exclusive expression of G-CSF receptor on myeloid progenitors in bone marrow CD34+ cells. Br J Haematol. 2000;109:153-161.
    • (2000) Br J Haematol , vol.109 , pp. 153-161
    • Ebihara, Y.1    Xu, M.J.2    Manabe, A.3
  • 7
    • 0037237648 scopus 로고    scopus 로고
    • Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide
    • Levesque JP, Hendy J, Takamatsu Y, Simmons PJ, Bendall LJ. Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide. J Clin Invest. 2003;111:187-196.
    • (2003) J Clin Invest , vol.111 , pp. 187-196
    • Levesque, J.P.1    Hendy, J.2    Takamatsu, Y.3    Simmons, P.J.4    Bendall, L.J.5
  • 8
    • 3042753829 scopus 로고    scopus 로고
    • Characterization of hematopoietic progenitor mobilization in protease-deficient mice
    • Levesque JP, Liu F, Simmons PJ, et al. Characterization of hematopoietic progenitor mobilization in protease-deficient mice. Blood. 2004;104:65-72.
    • (2004) Blood , vol.104 , pp. 65-72
    • Levesque, J.P.1    Liu, F.2    Simmons, P.J.3
  • 9
    • 0142188265 scopus 로고    scopus 로고
    • Chemokines acting via CXCR2 and CXCR4 control the release of neutrophils from the bone marrow and their return following senescence
    • Martin C, Burdon PC, Bridger G, Gutierrez-Ramos JC, Williams TJ, Rankin SM. Chemokines acting via CXCR2 and CXCR4 control the release of neutrophils from the bone marrow and their return following senescence. Immunity. 2003;19:583-593.
    • (2003) Immunity , vol.19 , pp. 583-593
    • Martin, C.1    Burdon, P.C.2    Bridger, G.3    Gutierrez-Ramos, J.C.4    Williams, T.J.5    Rankin, S.M.6
  • 10
    • 0036302147 scopus 로고    scopus 로고
    • G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4
    • Petit I, Szyper-Kravitz M, Nagler A, et al. G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4. Nat Immunol. 2002;3:687-694.
    • (2002) Nat Immunol , vol.3 , pp. 687-694
    • Petit, I.1    Szyper-Kravitz, M.2    Nagler, A.3
  • 11
    • 0036800086 scopus 로고    scopus 로고
    • G-CSF is an essential regulator of neutrophil trafficking from the bone marrow to the blood
    • Semerad CL, Liu F, Gregory AD, Stumpf K, Link DC. G-CSF is an essential regulator of neutrophil trafficking from the bone marrow to the blood. Immunity. 2002;17:413-423.
    • (2002) Immunity , vol.17 , pp. 413-423
    • Semerad, C.L.1    Liu, F.2    Gregory, A.D.3    Stumpf, K.4    Link, D.C.5
  • 12
    • 33744983304 scopus 로고    scopus 로고
    • Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells
    • Kollet O, Dar A, Shivtiel S, et al. Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells. Nat Med. 2006;12:657-664.
    • (2006) Nat Med , vol.12 , pp. 657-664
    • Kollet, O.1    Dar, A.2    Shivtiel, S.3
  • 13
    • 0034120373 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of AMD-3100, a novel antagonist of the CXCR-4 chemokine receptor, in human volunteers
    • Hendrix CW, Flexner C, MacFarland RT, et al. Pharmacokinetics and safety of AMD-3100, a novel antagonist of the CXCR-4 chemokine receptor, in human volunteers. Antimicrob Agents Chemother. 2000;44:1667-1673.
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 1667-1673
    • Hendrix, C.W.1    Flexner, C.2    MacFarland, R.T.3
  • 14
    • 0035871880 scopus 로고    scopus 로고
    • CXCR-4 desensitization is associated with tissue localization of hemopoietic progenitor cells
    • Shen H, Cheng T, Olszak I, et al. CXCR-4 desensitization is associated with tissue localization of hemopoietic progenitor cells. J Immunol. 2001;166:5027-5033.
    • (2001) J Immunol , vol.166 , pp. 5027-5033
    • Shen, H.1    Cheng, T.2    Olszak, I.3
  • 15
    • 2942523585 scopus 로고    scopus 로고
    • Cellular niches controlling B lymphocyte behavior within bone marrow during development
    • Tokoyoda K, Egawa T, Sugiyama T, Choi BI, Nagasawa T. Cellular niches controlling B lymphocyte behavior within bone marrow during development. Immunity. 2004;20:707-718.
    • (2004) Immunity , vol.20 , pp. 707-718
    • Tokoyoda, K.1    Egawa, T.2    Sugiyama, T.3    Choi, B.I.4    Nagasawa, T.5
  • 16
    • 33845445939 scopus 로고    scopus 로고
    • Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches
    • Sugiyama T, Kohara H, Noda M, Nagasawa T. Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches. Immunity. 2006;25:977-988.
    • (2006) Immunity , vol.25 , pp. 977-988
    • Sugiyama, T.1    Kohara, H.2    Noda, M.3    Nagasawa, T.4
  • 17
    • 0035941359 scopus 로고    scopus 로고
    • Matrix metalloproteinase activity inactivates the CXC chemokine stromal cell-derived factor-1
    • McQuibban GA, Butler GS, Gong JH, et al. Matrix metalloproteinase activity inactivates the CXC chemokine stromal cell-derived factor-1. J Biol Chem. 2001;276:43503-43508.
    • (2001) J Biol Chem , vol.276 , pp. 43503-43508
    • McQuibban, G.A.1    Butler, G.S.2    Gong, J.H.3
  • 18
    • 0037013221 scopus 로고    scopus 로고
    • Leukocyte elastase negatively regulates Stromal cell-derived factor-1 (SDF-1)/CXCR4 binding and functions by amino-terminal processing of SDF-1 and CXCR4
    • Valenzuela-Fernandez A, Planchenault T, Baleux F, et al. Leukocyte elastase negatively regulates Stromal cell-derived factor-1 (SDF-1)/CXCR4 binding and functions by amino-terminal processing of SDF-1 and CXCR4. J Biol Chem. 2002;277:15677-15689.
    • (2002) J Biol Chem , vol.277 , pp. 15677-15689
    • Valenzuela-Fernandez, A.1    Planchenault, T.2    Baleux, F.3
  • 19
    • 27644517442 scopus 로고    scopus 로고
    • G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow
    • Semerad CL, Christopher MJ, Liu F, et al. G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow. Blood. 2005;106:3020-3027.
    • (2005) Blood , vol.106 , pp. 3020-3027
    • Semerad, C.L.1    Christopher, M.J.2    Liu, F.3
  • 20
    • 33746605148 scopus 로고    scopus 로고
    • G-CSF down-regulation of CXCR4 expression identified as a mechanism for mobilization of myeloid cells
    • Kim HK, De La Luz Sierra M, Williams CK, Gulino AV, Tosato G. G-CSF down-regulation of CXCR4 expression identified as a mechanism for mobilization of myeloid cells. Blood. 2006;108:812-820.
    • (2006) Blood , vol.108 , pp. 812-820
    • Kim, H.K.1    De La Luz Sierra, M.2    Williams, C.K.3    Gulino, A.V.4    Tosato, G.5
  • 21
    • 0033168336 scopus 로고    scopus 로고
    • Human CD34(+) cells express CXCR4 and its ligand stromal cell-derived factor-1. Implications for infection by T-cell tropic human immunodeficiency virus
    • Aiuti A, Turchetto L, Cota M, et al. Human CD34(+) cells express CXCR4 and its ligand stromal cell-derived factor-1. Implications for infection by T-cell tropic human immunodeficiency virus. Blood. 1999;94:62-73.
    • (1999) Blood , vol.94 , pp. 62-73
    • Aiuti, A.1    Turchetto, L.2    Cota, M.3
  • 22
    • 0035186585 scopus 로고    scopus 로고
    • Plasma levels of SDF-1 and expression of SDF-1 receptor on CD34+ cells in mobilized peripheral blood of non-Hodgkin's lymphoma patients
    • Gazitt Y, Liu Q. Plasma levels of SDF-1 and expression of SDF-1 receptor on CD34+ cells in mobilized peripheral blood of non-Hodgkin's lymphoma patients. Stem Cells. 2001;19:37-45.
    • (2001) Stem Cells , vol.19 , pp. 37-45
    • Gazitt, Y.1    Liu, Q.2
  • 23
    • 0037244284 scopus 로고    scopus 로고
    • Intrinsic requirement for zinc finger transcription factor Gfi-1 in neutrophil differentiation
    • Hock H, Hamblen MJ, Rooke HM, et al. Intrinsic requirement for zinc finger transcription factor Gfi-1 in neutrophil differentiation. Immunity. 2003;18:109-120.
    • (2003) Immunity , vol.18 , pp. 109-120
    • Hock, H.1    Hamblen, M.J.2    Rooke, H.M.3
  • 24
    • 33644843788 scopus 로고    scopus 로고
    • Zinc-finger transcription factor Gfi-1: Versatile regulator of lymphocytes, neutrophils and hematopoietic stem cells
    • Hock H, Orkin SH. Zinc-finger transcription factor Gfi-1: versatile regulator of lymphocytes, neutrophils and hematopoietic stem cells. Curr Opin Hematol. 2006;13:1-6.
    • (2006) Curr Opin Hematol , vol.13 , pp. 1-6
    • Hock, H.1    Orkin, S.H.2
  • 25
    • 0036510161 scopus 로고    scopus 로고
    • Inflammatory reactions and severe neutropenia in mice lacking the transcriptional repressor Gfi1
    • Karsunky H, Zeng H, Schmidt T, et al. Inflammatory reactions and severe neutropenia in mice lacking the transcriptional repressor Gfi1. Nat Genet. 2002;30:295-300.
    • (2002) Nat Genet , vol.30 , pp. 295-300
    • Karsunky, H.1    Zeng, H.2    Schmidt, T.3
  • 26
    • 7244231429 scopus 로고    scopus 로고
    • Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells
    • Hock H, Hamblen MJ, Rooke HM, et al. Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells. Nature. 2004;431:1002-1007.
    • (2004) Nature , vol.431 , pp. 1002-1007
    • Hock, H.1    Hamblen, M.J.2    Rooke, H.M.3
  • 27
    • 8144220648 scopus 로고    scopus 로고
    • Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells
    • Zeng H, Yucel R, Kosan C, Klein-Hitpass L, Moroy T. Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells. EMBO J. 2004;23:4116-4125.
    • (2004) EMBO J , vol.23 , pp. 4116-4125
    • Zeng, H.1    Yucel, R.2    Kosan, C.3    Klein-Hitpass, L.4    Moroy, T.5
  • 28
    • 0023182058 scopus 로고
    • Cytokine-dependent granulocytic differentiation. Regulation of proliferative and differentiative responses in a murine progenitor cell line
    • Valtieri M, Tweardy DJ, Caracciolo D, et al. Cytokine-dependent granulocytic differentiation. Regulation of proliferative and differentiative responses in a murine progenitor cell line. J Immunol. 1987;138:3829-3835.
    • (1987) J Immunol , vol.138 , pp. 3829-3835
    • Valtieri, M.1    Tweardy, D.J.2    Caracciolo, D.3
  • 29
    • 0036284957 scopus 로고    scopus 로고
    • Growth factor independent-1 induced by IL-4 regulates Th2 cell proliferation
    • Zhu J, Guo L, Min B, et al. Growth factor independent-1 induced by IL-4 regulates Th2 cell proliferation. Immunity. 2002;16:733-744.
    • (2002) Immunity , vol.16 , pp. 733-744
    • Zhu, J.1    Guo, L.2    Min, B.3
  • 30
    • 0037089405 scopus 로고    scopus 로고
    • Regulation of endothelial cell branching morphogenesis by endogenous chemokine stromal-derived factor-1
    • Salvucci O, Yao L, Villalba S, Sajewicz A, Pittaluga S, Tosato G. Regulation of endothelial cell branching morphogenesis by endogenous chemokine stromal-derived factor-1. Blood. 2002;99:2703-2711.
    • (2002) Blood , vol.99 , pp. 2703-2711
    • Salvucci, O.1    Yao, L.2    Villalba, S.3    Sajewicz, A.4    Pittaluga, S.5    Tosato, G.6
  • 31
    • 0141828145 scopus 로고    scopus 로고
    • Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL
    • Staller P, Sulitkova J, Lisztwan J, Moch H, Oakeley EJ, Krek W. Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL. Nature. 2003;425:307-311.
    • (2003) Nature , vol.425 , pp. 307-311
    • Staller, P.1    Sulitkova, J.2    Lisztwan, J.3    Moch, H.4    Oakeley, E.J.5    Krek, W.6
  • 32
    • 0036024955 scopus 로고    scopus 로고
    • Identification of unknown target genes of human transcription factors using chromatin immunoprecipitation
    • Weinmann AS, Farnham PJ. Identification of unknown target genes of human transcription factors using chromatin immunoprecipitation. Methods. 2002;26:37-47.
    • (2002) Methods , vol.26 , pp. 37-47
    • Weinmann, A.S.1    Farnham, P.J.2
  • 33
    • 0031895515 scopus 로고    scopus 로고
    • The Gfi-1B proto-oncoprotein represses p21WAF1 and inhibits myeloid cell differentiation
    • Tong B, Grimes HL, Yang TY, et al. The Gfi-1B proto-oncoprotein represses p21WAF1 and inhibits myeloid cell differentiation. Mol Cell Biol. 1998;18:2462-2473.
    • (1998) Mol Cell Biol , vol.18 , pp. 2462-2473
    • Tong, B.1    Grimes, H.L.2    Yang, T.Y.3
  • 34
    • 33744951302 scopus 로고    scopus 로고
    • Increased CCAAT enhancer-binding protein epsilon (C/EB-Pepsilon) expression and premature apoptosis in myeloid cells expressing Gfi-1 N382S mutant associated with severe congenital neutropenia
    • Zhuang D, Qiu Y, Kogan SC, Dong F. Increased CCAAT enhancer-binding protein epsilon (C/EB-Pepsilon) expression and premature apoptosis in myeloid cells expressing Gfi-1 N382S mutant associated with severe congenital neutropenia. J Biol Chem. 2006;281:10745-10751.
    • (2006) J Biol Chem , vol.281 , pp. 10745-10751
    • Zhuang, D.1    Qiu, Y.2    Kogan, S.C.3    Dong, F.4
  • 35
    • 18244390470 scopus 로고    scopus 로고
    • The unique N-terminus of R-ras is required for Rac activation and precise regulation of cell migration
    • Holly SP, Larson MK, Parise LV. The unique N-terminus of R-ras is required for Rac activation and precise regulation of cell migration. Mol Biol Cell. 2005;16:2458-2469.
    • (2005) Mol Biol Cell , vol.16 , pp. 2458-2469
    • Holly, S.P.1    Larson, M.K.2    Parise, L.V.3
  • 36
    • 0035102228 scopus 로고    scopus 로고
    • STAT-3 activation is required for normal G-CSF-dependent proliferation and granulocytic differentiation
    • McLemore ML, Grewal S, Liu F, et al. STAT-3 activation is required for normal G-CSF-dependent proliferation and granulocytic differentiation. Immunity. 2001;14:193-204.
    • (2001) Immunity , vol.14 , pp. 193-204
    • McLemore, M.L.1    Grewal, S.2    Liu, F.3
  • 37
    • 0036338213 scopus 로고    scopus 로고
    • STAT3 is a negative regulator of granulopoiesis but is not required for G-CSF-dependent differentiation
    • Lee CK, Raz R, Gimeno R, et al. STAT3 is a negative regulator of granulopoiesis but is not required for G-CSF-dependent differentiation. Immunity. 2002;17:63-72.
    • (2002) Immunity , vol.17 , pp. 63-72
    • Lee, C.K.1    Raz, R.2    Gimeno, R.3
  • 38
    • 0037687417 scopus 로고    scopus 로고
    • Targets of the transcriptional repressor oncoprotein Gfi-1
    • Duan Z, Horwitz M. Targets of the transcriptional repressor oncoprotein Gfi-1. Proc Natl Acad Sci U S A. 2003;100:5932-5937.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 5932-5937
    • Duan, Z.1    Horwitz, M.2
  • 39
    • 0038757823 scopus 로고    scopus 로고
    • Mutations in proto-oncogene GFI1 cause human neutropenia and target ELA2
    • Person RE, Li FQ, Duan Z, et al. Mutations in proto-oncogene GFI1 cause human neutropenia and target ELA2. Nat Genet. 2003;34:308-312.
    • (2003) Nat Genet , vol.34 , pp. 308-312
    • Person, R.E.1    Li, F.Q.2    Duan, Z.3
  • 40
    • 0029775576 scopus 로고    scopus 로고
    • The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry
    • Bleul CC, Farzan M, Choe H, et al. The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature. 1996;382:829-833.
    • (1996) Nature , vol.382 , pp. 829-833
    • Bleul, C.C.1    Farzan, M.2    Choe, H.3
  • 41
    • 0033119201 scopus 로고    scopus 로고
    • The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment
    • Ma Q, Jones D, Springer TA. The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment. Immunity. 1999;10:463-471.
    • (1999) Immunity , vol.10 , pp. 463-471
    • Ma, Q.1    Jones, D.2    Springer, T.A.3
  • 42
    • 0035282432 scopus 로고    scopus 로고
    • Involvement of chemokine receptors in breast cancer metastasis
    • Muller A, Homey B, Soto H, et al. Involvement of chemokine receptors in breast cancer metastasis. Nature. 2001;410:50-56.
    • (2001) Nature , vol.410 , pp. 50-56
    • Muller, A.1    Homey, B.2    Soto, H.3
  • 43
    • 18844428327 scopus 로고    scopus 로고
    • Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
    • Orimo A, Gupta PB, Sgroi DC, et al. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell. 2005;121:335-348.
    • (2005) Cell , vol.121 , pp. 335-348
    • Orimo, A.1    Gupta, P.B.2    Sgroi, D.C.3
  • 44
    • 23944483709 scopus 로고    scopus 로고
    • ERM is required for transcriptional control of the spermatogonial stem cell niche
    • Chen C, Ouyang W, Grigura V, et al. ERM is required for transcriptional control of the spermatogonial stem cell niche. Nature. 2005;436:1030-1034.
    • (2005) Nature , vol.436 , pp. 1030-1034
    • Chen, C.1    Ouyang, W.2    Grigura, V.3
  • 45
    • 17644443312 scopus 로고    scopus 로고
    • The transcriptional repressor Gfi1 affects development of early, uncommitted c-Kit+ T cell progenitors and CD4/CD8 lineage decision in the thymus
    • Yucel R, Karsunky H, Klein-Hitpass L, Moroy T. The transcriptional repressor Gfi1 affects development of early, uncommitted c-Kit+ T cell progenitors and CD4/CD8 lineage decision in the thymus. J Exp Med. 2003;197:831-844.
    • (2003) J Exp Med , vol.197 , pp. 831-844
    • Yucel, R.1    Karsunky, H.2    Klein-Hitpass, L.3    Moroy, T.4
  • 46
    • 3442884110 scopus 로고    scopus 로고
    • Gulino AV. WHIM syndrome: a genetic disorder of leukocyte trafficking. Curr Opin Allergy Clin Immunol. 2003;3:443-450.
    • Gulino AV. WHIM syndrome: a genetic disorder of leukocyte trafficking. Curr Opin Allergy Clin Immunol. 2003;3:443-450.
  • 47
    • 0037656291 scopus 로고    scopus 로고
    • Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease
    • Hernandez PA, Gorlin RJ, Lukens JN, et al. Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease. Nat Genet. 2003;34:70-74.
    • (2003) Nat Genet , vol.34 , pp. 70-74
    • Hernandez, P.A.1    Gorlin, R.J.2    Lukens, J.N.3
  • 48
    • 0033591347 scopus 로고    scopus 로고
    • Multiple signals mediate proliferation, differentiation, and survival from the granulocyte colony-stimulating factor receptor in myeloid 32D cells
    • Ward AC, Smith L, de Koning JP, van Aesch Y, Touw IP. Multiple signals mediate proliferation, differentiation, and survival from the granulocyte colony-stimulating factor receptor in myeloid 32D cells. J Biol Chem. 1999;274:14956-14962.
    • (1999) J Biol Chem , vol.274 , pp. 14956-14962
    • Ward, A.C.1    Smith, L.2    de Koning, J.P.3    van Aesch, Y.4    Touw, I.P.5
  • 49
    • 0034128534 scopus 로고    scopus 로고
    • Cloning and characterization of the TATA-less promoter from the human GFI1 proto-oncogene
    • Liu S, Cowell JK. Cloning and characterization of the TATA-less promoter from the human GFI1 proto-oncogene. Ann Hum Genet. 2000;64:83-86.
    • (2000) Ann Hum Genet , vol.64 , pp. 83-86
    • Liu, S.1    Cowell, J.K.2
  • 50
    • 0034329453 scopus 로고    scopus 로고
    • The zinc finger protein Gfi-1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3
    • Rodel B, Tavassoli K, Karsunky H, et al. The zinc finger protein Gfi-1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3. EMBO J. 2000;19:5845-5855.
    • (2000) EMBO J , vol.19 , pp. 5845-5855
    • Rodel, B.1    Tavassoli, K.2    Karsunky, H.3
  • 51
    • 0032540493 scopus 로고    scopus 로고
    • Genomic organization and promoter characterization of human CXCR4 gene
    • Caruz A, Samsom M, Alonso JM, et al. Genomic organization and promoter characterization of human CXCR4 gene. FEBS Lett. 1998;426:271-278.
    • (1998) FEBS Lett , vol.426 , pp. 271-278
    • Caruz, A.1    Samsom, M.2    Alonso, J.M.3
  • 52
    • 0033562986 scopus 로고    scopus 로고
    • USF/c-Myc enhances, while Yin-Yang 1 suppresses, the promoter activity of CXCR4, a coreceptor for HIV-1 entry
    • Moriuchi M, Moriuchi H, Margolis DM, Fauci AS. USF/c-Myc enhances, while Yin-Yang 1 suppresses, the promoter activity of CXCR4, a coreceptor for HIV-1 entry. J Immunol. 1999;162:5986-5992.
    • (1999) J Immunol , vol.162 , pp. 5986-5992
    • Moriuchi, M.1    Moriuchi, H.2    Margolis, D.M.3    Fauci, A.S.4
  • 53
    • 16844386963 scopus 로고    scopus 로고
    • Carboxyl-terminal Src kinase homologous kinase negatively regulates the chemokine receptor CXCR4 through YY1 and impairs CXCR4/CXCL12 (SDF-1alpha)-mediated breast cancer cell migration
    • Lee BC, Lee TH, Zagozdzon R, Avraham S, Usheva A, Avraham HK. Carboxyl-terminal Src kinase homologous kinase negatively regulates the chemokine receptor CXCR4 through YY1 and impairs CXCR4/CXCL12 (SDF-1alpha)-mediated breast cancer cell migration. Cancer Res. 2005;65:2840-2845.
    • (2005) Cancer Res , vol.65 , pp. 2840-2845
    • Lee, B.C.1    Lee, T.H.2    Zagozdzon, R.3    Avraham, S.4    Usheva, A.5    Avraham, H.K.6
  • 54
    • 0038498102 scopus 로고    scopus 로고
    • NF-kappaB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4
    • Helbig G, Christopherson KW 2nd Bhat-Nakshatri P, et al. NF-kappaB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4. J Biol Chem. 2003;278:21631-21638.
    • (2003) J Biol Chem , vol.278 , pp. 21631-21638
    • Helbig, G.1    Christopherson 2nd, K.W.2    Bhat-Nakshatri, P.3
  • 55
    • 34249043939 scopus 로고    scopus 로고
    • Negative regulation of chemokine receptor CXCR4 by tumor suppressor p53 in breast cancer cells: Implications of p53 mutation or isoform expression on breast cancer cell invasion
    • Mehta SA, Christopherson KW, Bhat-Nakshatri P, et al. Negative regulation of chemokine receptor CXCR4 by tumor suppressor p53 in breast cancer cells: implications of p53 mutation or isoform expression on breast cancer cell invasion. Oncogene. 2006;26:3329-3337.
    • (2006) Oncogene , vol.26 , pp. 3329-3337
    • Mehta, S.A.1    Christopherson, K.W.2    Bhat-Nakshatri, P.3


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