Carboxyl-terminal Src kinase homologous kinase negatively regulates the chemokine receptor CXCR4 through YY1 and impairs CXCR4/CXCL12 (SDF-1α)-mediated breast cancer cell migration

Cancer Research

Volumn 65, Issue 7, 2005, Pages 2840-2845

  Lee, Byeong Chel ^a   Lee, Tae Hee ^a   Zagozdzon, Radoslaw ^a   Avraham, Shalom ^a   Usheva, Anny ^a   Avraham, Hava Karsenty ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HARVARD INSTITUTES OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; BINDING PROTEIN; CHEMOKINE RECEPTOR CXCR4; MAX PROTEIN; MYC PROTEIN; PROTEIN TYROSINE KINASE; STROMAL CELL DERIVED FACTOR 1; STROMAL CELL DERIVED FACTOR 1ALPHA; UNCLASSIFIED DRUG; YY1 BINDING PROTEIN;

ARTICLE; BINDING SITE; BREAST CANCER; CANCER CELL; CARBOXY TERMINAL SEQUENCE; CELL MIGRATION; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; ENZYME ACTIVITY; FLUORESCENCE ACTIVATED CELL SORTING; GENETIC ANALYSIS; HUMAN; HUMAN CELL; MUTATION; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; STATISTICAL SIGNIFICANCE;

BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CHEMOKINES, CXC; DNA-BINDING PROTEINS; DOWN-REGULATION; ERYTHROID-SPECIFIC DNA-BINDING FACTORS; HUMANS; PROMOTER REGIONS (GENETICS); PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-MYC; PROTO-ONCOGENE PROTEINS PP60(C-SRC); RECEPTORS, CXCR4; TRANSCRIPTION FACTORS; TRANSFECTION; YY1 TRANSCRIPTION FACTOR;

EID: 16844386963     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-04-3309     Document Type: Article

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