Platelet Monoamine Oxidase, Personality and Alcoholism: The Rise, Fall and Resurrection

NeuroToxicology

Volumn 25, Issue 1-2, 2004, Pages 79-89

  Oreland, Lars ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Alcoholism; AP 2; Mitochondria; Monoamine systems; Personality; Platelet monoamine oxidase; Serotonin; Transcription factors

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); CIGARETTE SMOKE; MONOAMINE OXIDASE INHIBITOR; RECEPTOR; TRANSCRIPTION FACTOR AP 2;

ALCOHOLISM; BEHAVIOR; CIGARETTE SMOKING; ENZYME ACTIVITY; GENETIC MARKER; HUMAN; IMPULSIVENESS; MITOCHONDRION; MONOAMINERGIC SYSTEM; NONHUMAN; OUTER MEMBRANE; PERSONALITY; PRIMATE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SUBSTANCE ABUSE; TRANSCRIPTION REGULATION;

GYMNOMYZA SAMOENSIS; PRIMATES;

EID: 0348046388     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-813X(03)00115-3     Document Type: Article

References (121)

1. af Klinteberg B, Oreland L. Hyperactive and aggressive behaviours in childhood as related to low platelet monoamine oxidase (MAO) activity at adult age: a longitudinal study of male subjects. Personal Individual Diff 1995;19:373-83.
2. af Klinteberg B, Oreland L, Hallman J, Wirsén A, Schalling D. Exploring the connections between platelet monoamine oxidase (MAO) activity and behaviour: relationships with performance in neuropsychological tasks. Neuropsychobiology 1990;23:188-96.
3. Anthenelli RM, Tipp J, Li TK, Magnes L, Schuckit MA, Rice J et al. Platelet monoamine oxidase activity in subgroups of alcoholics and controls: results from the Collaborative Study on the Genetics of Alcoholism. Alcohol: Clin Exp Res 1998;22:598-604.
4. Babor TF, Hofman M, DelBoca FK, Hesselbrock V, Meyer RE, Dolinsky ZS et al. Types of alcoholics. I. Evidence for an empirically derived typology based on indicators of vulnerability and severity. Arch Gen Psychiatr 1992;49:599-608.
5. Bach AWJ, Lan NC, Johnson DL, Abell CW, Bembenek ME, Kwan S-W et al. cDNA cloning of human liver monoamine oxidase A and B: molecular basis of differences in enzymatic properties. Proc Natl Acad Sci 1988;85:4934-8.
6. Bagdy G, Rihmer Z. Measurement of platelet monoamine oxidase activity in healthy human volunteers. Acta Physiol Hung 1986;68:19-24.
7. Berlin I, Anthenelli RM. Monoamine oxidase and tobacco smoking. Int J Neuropsychopharmacol 2001;4:33-42.
8. Berlin I, Said S, Spreux-Varoquaux O, Olivares R, Launay JM, Puech AJ. Monoamine oxidase A and B activities in heavy smokers. Biol Psychiatr 1995;38:756-61.
9. Berlin I, Spreux-Varoquaux O, Launay JM. Platelet monoamine oxidase B activity is inversely associated with plasma cotinine concentration. Nicotine Tob Res 2000;2:243-6.
10. Bongioanni P, Mondino C, Boccardi B, Borgna M, Castagna M. Monoamine oxidase molecular activity in platelets of parkinsonian and demented patients. Neurodegeneration 1996;5:351-7.
11. Boularand S, Darmon MC, Ravassard P, Mallet J. Characterization of the human tryptophan hydroxylase gene promoter: transcriptional regulation by cAMP requires a new motif distinct from the cAMP-responsive element. J Biol Chem 1995:270:3757-64.
12. Bradely CC, Blakely RD. Alternative splicing of the human serotonin transporter gene. J Neurochem 1997;69:1356-67.
13. Bridge TP, Soldo BJ, Phelps BH, Wise CD, Franacak MJ, Wyatt RJ. Platelet monoamine oxidase activity: demographic characteristics contribute to enzyme activity variability. J Gerontol 1985;40:23-8.
14. Brown GL, Goodwin FK, Ballenger JC, Goyer PF, Major LF. Aggression in humans correlates with cerebrospinal fluid amine metabolites. Psychiatr Res 1979;1:131-9.
15. Buchsbaum MS, Coursey RD, Murphy DL. The biochemical highrisk paradigm: behavioural and familial correlates of low platelet monoamine oxidase activity. Science (NY) 1976;194:339-41.
16. Chen K, Wu HF, Shih JC. The deduced amino acid sequences of human platelet and frontal cortex monoamine oxidase B are identical. J Neurochem 1993;61:187-90.
17. Cloninger CR, Bohman M, Sigvardssson S. Inheritance of alcohol abuse: cross-fostering analysis of adopted men. Arch Gen Psychiatr 1981;38:861-8.
18. Collins GGS, Sandler M. Human blood platelet monoamine oxidase. Biochem Pharmacol 1971;20:289-96.
19. Damberg M. Transcription factor AP-2 in relation to serotonergic functions in the central nervous system. Dissertation. Acta Universitatis Upsaliensis; 2002.
20. Damberg M, Garpenstrand H, Berggard C, Asberg M, Hallman J, Oreland L. The genotype of human transcription factor AP-2beta is associated with platelet monoamine oxidase B activity. Neurosci Lett 2000a;291:204-6.
21. Damberg M, Garpenstrand H, Forslund K, Rylander G, Oreland L. A polymorphic region in the human transcription factor AP-2β gene is associated with specific personality traits. Mol Psychiatr 2000b;5:220-4.
22. Damberg M, Eller M, Tönissaar M, Oreland L, Harro J. Levels of transcription factors AP-2alfa and AP-2beta in the brainstem are correlated to monoamine turnover in the rat forebrain. Neurosci Lett 2001a;313:102-4.
23. Damberg M, Garpenstrand H, Hallman J, Oreland L. Genetic mechanisms of behavior: don't about the transcription factors. Mol Psychiatr 2001b;6:503-10.
24. Demir B, Uçar G, Ulug B, Ulusoy S, Seving I, Batur S. Platelet monoamine oxidase activity in alcoholism subtypes: relationship to personality traits and executive functions. Alcohol Alcohol 2002;37:597-602.
25. de Leon J, Dadvand M, Canuso C, White AO, Stanilla JK, Simpson GM. Schizophrenia and smoking: an epidemiologic survey in a state hospital. Am J Psychiatr 1995;152:453-5.
26. Ebstein RP, Bejamin J, Belmaker RH. Eur J Pharmacol 2000;410:205-14.
27. Ekblom J, Garpenstrand H, Damberg M, Chen K, Shih JC, Oreland L. Transcription factor binding to the core promoter of the human monoamine oxidase B gene in the cerebral cortex and in blood cells. Neurosci Lett 1998;258:101-4.
28. Eysenck MJ, Eysenck SBG. Manual of the Eysenck personality questionnaire. London: Hodder and Stoughton; 1975.
29. Fahlke C, Garpenstrand H, Oreland L, Suomi S, Higley D. Platelet monoamine oxidase activity in a nonhuman primate model of type 2 excessive alcohol consumption. Am J Psychiatr 2002;159:2107-9.
30. Farren CK, Clare AW, Tipton KF, Dinan TG. Platelet MAO activity in subtypes of alcoholics and control in a homogenous population. J Psych Res 1998;32:49-54.
31. Fink JS, Reis DJ. Genetic variations in midbrain dopamine cell number: parallel with differences in responses to dopaminergic agonists and in naturalistic behaviors mediated by central dopaminergic systems. Brain Res 1981;19:335-49.
32. Fleissner A, Seifert R, Schneider K, Eckert W, Fuisting B. Platelet monoamine oxidase activity and schizophrenia-a myth that refuses to die? Eur Arch Psychiatr Neurol Sci 1987;237:8-15.
33. Fowler CJ, Ekstedt B, Egashira T, Kinemuchi H, Oreland L. The interaction between human platelet monoamine oxidase, its monoamine substrates and oxygen. Biochem Pharmacol 1979;28:3063-8.
34. Fowler CJ, Wiberg A, Oreland L, Marcusson J, Winblad B. The effect of age on the activity and molecular properties of human brain monoamine oxidase. J Neural Transm 1980;49:1-20.
35. Fowler JS, Volkow ND, Wang GJ, Pappas N, Logan J, MacGregor R et al. Inhibition of monoamine oxidase B in the brains of smokers. Nature 1996a;379:733-6.
36. Fowler JS, Volkow ND, Wang GJ, Pappas N, Logan J, Shea C et al. Brain monoamine oxidase A inhibition in cigarette smokers. Proc Natl Acad Sci USA 1996b;93:14065-9.
37. Fowler JS, Volkow ND, Logan J, Pappas N, King P, MacGregor R et al. An acute dose of nicotine does not inhibit MAO B baboon brain in vivo. Life Sci 1998;63:19-23.
38. Fowler JS, Wang GJ, Volkow ND, Franceschi D, Logan J, Pappas N et al. Smoking a single cigarette does not produce a measurable reduction in brain MAO B in non-smokers. Nicotine Tob Res 1999;1:325-9.
39. Fowler JS, Wang GJ, Volkow ND, Franceschi D, Logan J, Pappas N et al. Maintenance of brain monoamine oxidase B inhibition in smokers after overnight cigarette abstinence. Am J Psychiatr 2000;157:1864-6.
40. Fowler JS, Logan J, Wang G-J, Volkow N. Neurotoxicol 2003;24:75-82.
41. Garpenstrand H, Ekblom J, Forslund K, Rylander G, Oreland L. Platelet monoamine oxidase activity is related to MAOB intron 13 genotype. J Neural Transm 2000;107:523-30.
42. Garpenstrand H, Longato-Stadler E, af Klinteberg B, Grigorenko E, Damberg M, Oreland L et al. Low platelet MAO activity in Swedish criminal offenders. Eur Neuropsychopharmacol 2002;12:135-40.
43. Garrick NA, Redmond DE, Murphy DL. Primate-rodent monoamine oxidase differences. In: Singer TP, von Korff RW, Murphy DL, editors. Monoamine oxidase: structure, function, and altered functions. New York: Academic Press; 1979. p. 351-9.
44. Girmen AS, Baenziger J, Hotamisligil GS, Konradi C, Shalish C, Sullivan JL et al. Relationship between platelet monoamine oxidase B activity and alleles at the MAOB locus. J Neurochem 1992;59:2063-6.
45. Gottfries C-G, Oreland L, Wiberg Å, Winblad B. Lowered monoamine oxidase activity in brains from alcoholic suicides. J Neurochem 1975;25:667-73.
46. Grimsby J, Lan NC, Neve R, Chen K, Shih JC. Tissue distribution of human monoamine oxidase A and B mRNA. J Neurochem 1990;55:1166-9.
47. Hallikainen T, Saito T, Lachman HM, Volavka J, Pohjalainen T, Ryynanen OP et al. Association between low activity serotoninn transporter promoter genotype and early onset alcoholism with habitual impulsive violent behavior. Mol Psychiatr 1999;4:385-8.
48. Hallman J, von Knorring L, Oreland L. Personality disorders according to DSM-III-R and thrombocyte monoamine oxidase activity in type 1 and type 2 alcoholics. J Stud Alcohol 1996;57:155-61.
49. Hauptmann N, Shih JC. 2-Naphthylamine, a compound found in cigarette smoke, decreases both monoamine oxidase A and B catalytic activity. Life Sci 2001;68:1231-41.
50. Heinz A, Jones DW, Gorey JG, Bennet A, Suomi SJ, Weinberger DR et al. Mol Psychiatr 2003;8:231-4.
51. Higley JD, Suomi SJ, Linnoila M. A nonhuman primate model of type II excessive alcohol consumption? Part 1. Low cerebrospinal fluid 5-hydroxyindoleacetic acid concentrations and diminished social competence correlate with excessive alcohol consumption. Alcohol Clin Exp Res 1996a;20:629-42.
52. Higley JD, Mehlman PT, Poland RE, Taub DM, Vickers J, Suomi SJ et al. CSF testosterone and 5-HIAA correlate with different types of aggressive behaviors. Biol Psychiatr 1996b;40:1067-82.
53. Hotamisligil GS, Breakefield XO. Human monoamine oxidase a gene determines levels of enzyme activity. Am J Hum Genet 1991;49:383-92.
54. Huang LG, Bowden CL. Platelet monoamine oxidase response to lithium treatment in psychiatric patients. J Clin Psychopharmacol 1984;4:326-31.
55. Jarman J, Glover V, Sandler M, Turjanski N, Stern G. Platelet monoamine oxidase B activity in Parkinson's disease: a reevaluation. J Neural Trasm Park Dis Dement Sect 1993;5:14.
56. Khalil AA, Steyn S, Castagnoli Jr, N. Isolation and characterization of a monoamine oxidase inhibitor from tobacco leaves. Chem Res Toxicol 2000;13:31-5.
57. Kirk KM, Whitfield JB, Pang D, Heath AC, Martin NG. Genetic covariation of neuroticism with monoamine oxidase activity and smoking. Am J Med Gen 2001;105:700-6.
58. Kopstein AN, Crum RM, Celentano DD, Martin SS. Sensation seeking needs among 8th and 11th graders: characteristics associated with cigarette and marijuana use. Drug Alcohol Depend 2001;62:195-203.
59. Kruesi MJ, Rapoport JL, Hamburger S, Hibbs E, Potter WZ, Lenane M et al. Cerebrospinal fluid monoamine metabolites, aggression and impulsivity in disruptive behaviour disorders of children and adolescents. Arch Gen Psychiatr 1990;47:419-26.
60. Langbehn DR, Cadoret RJ, Caspres K, Troughton EP, Yucuis R. Genetic and environmental risk factors for the onset of drug use and problems in adoptees. Drug Alcohol Depend 2003;69:151-67.
61. Lesch K-P, Bengel D, Heils A, Sabol SZ, Greenberg D, Petri S et al. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 2000;274:1527-31.
62. Levitt P, Pintar JE, Breakefield XO. Immunocytochemical demonstration of monoamine oxidase B in brain astrocytes and serotonergic neurons. Proc Natl Acad Sci 1982;79:6385-9.
63. Mann J, Chiu E. Platelet monoamine oxidase activity in Huntington's chorea. J Neurol Neurosurg Psychiatr 1978;41:809-12.
64. Marcolin MA, Davis JM. Platelet monoamine oxidase activity in schizophrenia: a meta-analysis. Schizophrenia Res 1992;7:2 49-67.
65. Mendez-Alvarez E, Soto-Otero R, Sanchez-Sellero I, Lopez-Rivadulla-Lamas M. Inhibition of brain monoamine oxidase by adducts of 1,2,3,4-tetrahydroisoquinoline with components of cigarette smoke. Life Sci 1997;60:1719-927.
66. Mitchell PJ, Timmons PM, Herbert JM, Rigby PW, Tijan R. Transcription factor AP-2 is expressed in neural cell lineages during mouse embryogenesis. Genes Dev 1991;5:105-19.
67. Murphy DL. Clinical, genetic, hormonal and drug influences on the activity of human platelet monoamine oxidase. In: Monoamine oxidase and its inhibition, vol. 39. Ciba Foundation Symposium. Amsterdam: Elsevier; 1976. p. 341-51.
68. Murphy DL, Wyatt RJ. Reduced monoamine oxidase activity in blood platelets from schizophrenic patients. Nature 1972;238:225-6.
69. Murphy DL, Wright C, Buchsbaum M, Nichols A, Costa JL, Wyatt RJ. Platelet and plasma amine oxidase activity in 680 normals: sex and age differences and stability over time. Biochem Med 1976;16:254-6.
70. Norman TR, Chamberlain KG, French MA, Burrows GD. Platelet monoamine oxidase activity and cigarette smoking. J Affect Disord 1982;4:73-7.
71. Norman TR, Chiu E, French MA. Platelet monoamine oxidase activity in patients with Huntington's disease. Clin Exp Pharmacol Physiol 1987a;14:547-50.
72. Norman TR, Chamberlain KG, French MA. Platelet monoamine oxidase: low activity in cigarette smokers. Psychiatr Res 1987b; 20:199-205.
73. Oreland L. The activity of human brain and thrombocyte monoamine oxidase (MAO) in relation to various psychiatric disorders. I. MAO activity in some disease states. In: Singer T, von Korff R, Murphy D, editors. Monoamine oxidase; structure, function and altered functions. New York: Academic Press; 1979. p. 379-87.
74. Oreland L. Monoamine Oxidase in neuropsychiatric disorders. In: Yasuhara H, Parvez SH, Sandler, M, Oguchi K, Nagatsu T, editors. Monoamine oxidase: basic and clinical aspects. Utrecht, The Netherlands: VSP press; 1993. p. 219-47.
75. Oreland L, Gottfries CG. Platelet and brain monoamine oxidase in aging and in dementia of Alzheimer's type. Progr Neuro-Psycho-Pharmacol Biol Psychiatr 1986;10:533-40.
76. Oreland L, Hallman J. The correlation between platelet MAO activity and personality: a short review of findings and a discussion on possible mechanisms. In: Yu PU, KF, Boulton AA, editors. Progr Brain Res, vol. 106. Amsterdam: Elsevier; 1995. p. 77-84.
77. Oreland L, Shaskan EG. Monoamine oxidase activity as a biological marker. Trends Pharmacol Sci 1983;4:339-41.
78. Oreland L, Fowler CJ, Schalling D. Low platelet monoamine oxidase activity in cigarette smokers. Life Sci 1981a;29:2511-8.
79. Oreland L, Wiberg Å, Åsberg M, Träskman L, Sjöstrand L, Thorén P et al. Platelet MAO activity and monoamine metabolites in cerebrospinal fluid in depressed and suicidal patients and in healthy controls. Psychiatr Res 1981b;4:21-9.
80. Oreland L, Garpenstrand H, Damberg M, Alm PO, Thorell LH, af Klinteberg B et al. The correlation between platelet MAO activity and personality-the effect of smoking and possible mechanisms behind the correlation. Neurobiology 1999;7:191-203.
81. Oreland L, Damberg M, Hallman J, Garpenstrand H. Smoking only explains part of the association between platelet monoamine oxidase activity and personality. J Neural Transm 2002;109:963-75.
82. Oxenstierna G, Edman G, Iselius L, Oreland L, Ross S, Sedvall G. Concentrations of monoamine metabolites in the CSF of twins and unrelated subjects: a genetic study. J Psychiatr Res 1986;20:19-29.
83. Parsian A, Cloninger CR. Serotonergic pathway genes and subtypes of alcoholism: association studies. Psychiatr Genet 2001;11:89-94.
84. Paasonen MK, Solatunturi E, Kivalo E. Monoamine oxidase activity of blood platelets and their ability to store 5-hydroxytryptamine in some mental deficiencies. Psychopharmacologia 1964;6:120-4.
85. Pedersen NL, Oreland L, Reynolds C, McClearn GE. Importance of genetic influence on thrombocyte MAO activity in twins reared together. Psychiatr Res 1993;6:239-51.
86. Perkins KA, Gerlach D, Broge M, Grobe JE, Wilson A. Greater sensitivity to objective effects of nicotine in nonsmokers high in sensation seeking. Exp Clin Psychopharmacol 2000;8:462-71.
87. Prince J, Shia J, Båve U, Annerén G, Oreland L. Mitochondrial enzyme deficiencies in Down's syndrome. J Neural Trans 1994;8:171-81.
88. Propping P, Ray E-R, Friedl W, Beckman H. Platelet monoamine oxidase in healthy subjects: the "biochemical high-risk paradigm" revisited. Arch Psychiatr Nervenkr 1981;230:209-19.
89. Ravaja N, Keltikangas-Jarvinen K. Cloninger's temperament and character dimensions in young adulthood and their relation to characteristics of parental alcohol use and smoking. J Stud Alcohol 2001;62:98-104.
90. Redmond DE, Murphy DL, Baulu J. Platelet monoamine oxidase activity correlates with social affiliative and agonistic behaviors in normal rhesus monkeys. Psychosom Med 1979;41:87-100.
91. Regland B, Gottfries C-G, Oreland L. Vitamin B-12 induced reductions of platelet MAO activity in patients with dementia and pernicious anemia. Eur Arch Psych Clin Neurosci 1991;240:288-91.
92. Reif A, Lesch K-P. Toward a molecular architecture of personality. Behav Brain Res 2003;139:1-20.
93. Reuter M, Netter P. The influence of personality on nicotine craving: a hierarchical multivariate statistical prediction model. Neuropsychobiology 2001;44:47-53.
94. Robinson DS, Davis JM, Nies A, Colburn RW, Davis JN, Bourne HR et al. Ageing, monoamines and monoamine oxidase levels. Lancet 1972;1:290-1.
95. Sandler M, Youdim MBH, Hanington E. A phenylethylamine oxidising defect in migraine. Nature 1974;250:335-7.
96. Schalling D. The trait-situation and the physiological correlates of behaviour. In: Magnusson D, Endler NS, editors. Personality at the cross-roads. Hillsdale, NJ: Lawrence Erlbaum; 1977.
97. Sherif F, Hallman J, Oreland L. Low platelet gamma-aminobutyrate aminotransferase and monoamine oxidase activities in chronic alcoholic patients. Alcohol: Clin Exp Res 1992;16:1014-20.
98. Shih JC, Chen K. MAO-A and -B knock-out mice exhibit distinctly different behavior. Neurobiology 1999;7:235-46.
99. Simpson GM, Shih JC, Chen K, Flowers C, Kumazawa T, Spring B. Schizophrenia, monoamine oxidase activity, and cigarette smoking. Neuropsychopharmacology 1999;20:392-4.
100. Snell LD, Glanz J, Tabakoff B. Relationships between effects of smoking, gender, and alcohol dependence on platelet monoamine oxidase-B: activity, affinity labeling, and protein measurements. Alcohol Clin Exp Res 2002;26:1105-13.
101. Sofuoglu S, Dogan P, Kose K, Esel E, Basturk M, Oguz H et al. Changes in platelet monoamine oxidase and plasma dopamine-beta-hydroxylase activities in litium-treated bipolar patients. Psychiatr Res 1995;29(59):165-70.
102. Sostek AJ, Miller Sostek A, Murphy DL, Bond Martin E, Smith Born W. Cord blood amine oxidase activities relate to arousal and motor functioning in human newborns. Life Sci 1981;28:2561-8.
103. Spielberger CD, Jacobs GA. Personality and smoking behavior. J Pers Assess 1982;46:396-403.
104. Stålenheim EG, von Knorring L, Oreland L. Platelet monoamine oxidase activity as a biological marker in a Swedish forensic psychiatric population. Psychiatr Res 1997;6:79-87.
105. Sullivan PF, Kendler KS. The genetic epidemiology of smoking. Nicotine Tob Res 1999;1(Suppl 2):S51-7.
106. Takahashi S, Tani N, Yamane H. Monoamine oxidase activity in blood platelets in alcoholism. Fol Psychiatr et Neurol Jpn 1976;30:455-62.
107. Tipton KF. What is it that L-deprenyl (selegiline) might do? Clin Pharmacol Ther 1994;56:781-96.
108. Ward PB, Catts SV, Norman TR, Burrows GD, McConaghy N. Low platelet monoamine oxidase and sensation seeking in males: an established relationship? Acta Psychiatr Scand 1987;75:86-90.
109. Whitfield JB, Pang D, Bucholz KK, Madden PA, Heath AC, Statham DJ et al. Monoamine oxidase: associations with alcohol dependence, smoking and other measures of psychopathology. Psychol Med 2000;30:443-54.
110. Wiberg Å, Gottfries C-G, Oreland L. Low platelet monoamine oxidase activity in human alcoholics. Med Biol 1977;55:181-6.
111. Winblad B, Gottfries C-G, Oreland L, Wiberg Å. Monoamine oxidase in human platelets and brains of non-neurological geriatric patients. Med Biol 1979;57:129-32.
112. Virkkunen M, Linnoila M. Brain serotonin, type 2 alcoholism and impulsive violence. J Stud Alcohol Suppl 1993;11:163-9.
113. von Knorring L, Oreland L. Personality traits and platelet MAO in tobacco smokers. Psychol Med 1985;15:327-34.
114. von Knorring L, Oreland L. Platelet MAO activity in type I/type II alcoholics. Alcohol: Clin Exp Res 1996;20:224-30.
115. von Knorring L, Oreland L, Winblad B. Personality traits related to monoamine oxidase activity in platelets. Psychiatr Res 1984;12:11-26.
116. von Knorring A-L, Bohman M, von Knorring L, Oreland L. Platelet oxidase activity as a biological marker in subgroups of alcoholism. Acta Psychiatr Scand 1985;72:51-8.
117. Wong WK, Chen K, Shih JC. Regulation of human monoamine oxidase B gene by Sp1 and Sp3. Mol Pharmacol 2001;59:852-9.
118. Wyatt RJ, Potkin SG, Murphy DL. Platelet monoamine oxidase activity in schizophrenia: a review of the data. Am J Psychiatr 1979;136:377-85.
119. Yu PH, Boulton AA. Irreversible inhibition of monoamine oxidase by some components of cigarette smoke. Life Sci 1987;41:675-82.
120. Zhu Q-S, Grimsby J, Chen K, Shih JC. Promoter organization and activity of human monoamine oxidase (MAO) A and B genes. J Neurosci 1992;12:4437-44.
121. Zuckerman M. Sensation seeking: beyond the optimal level of arousal. Hillsdale, NJ: Lawrence Erlbaum; 1979.