-
1
-
-
14944385553
-
Global cancer statistics, 2002
-
Parkin,D.M. et al. (2005) Global cancer statistics, 2002. CA Cancer J. Clin., 55, 74-108.
-
(2005)
CA Cancer J. Clin
, vol.55
, pp. 74-108
-
-
Parkin, D.M.1
-
2
-
-
0034644185
-
Environmental and heritable factors in the causation of cancer - analyses of cohorts of twins from Sweden, Denmark, and Finland
-
Lichtenstein,P. et al. (2000) Environmental and heritable factors in the causation of cancer - analyses of cohorts of twins from Sweden, Denmark, and Finland. N. Engl. J. Med., 343, 78-85.
-
(2000)
N. Engl. J. Med
, vol.343
, pp. 78-85
-
-
Lichtenstein, P.1
-
3
-
-
3142733741
-
Familial risk for colorectal cancers are mainly due to heritable causes
-
Hemminki, K. et al.. (2004) Familial risk for colorectal cancers are mainly due to heritable causes. Cancer Epidemiol. Biomarkers Prev., 13, 1253-1256.
-
(2004)
Cancer Epidemiol. Biomarkers Prev
, vol.13
, pp. 1253-1256
-
-
Hemminki, K.1
-
4
-
-
4444272418
-
The search for low-penetrance cancer susceptibility alleles
-
Houlston,R.S. et al. (2004) The search for low-penetrance cancer susceptibility alleles. Oncogene, 23, 6471-6476.
-
(2004)
Oncogene
, vol.23
, pp. 6471-6476
-
-
Houlston, R.S.1
-
5
-
-
4944240144
-
Genetic predisposition to colorectal cancer
-
de la Chapelle, A. (2004) Genetic predisposition to colorectal cancer. Nat. Rev. Cancer, 4, 769-780.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 769-780
-
-
de la Chapelle, A.1
-
6
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
Kinzler,K.W. et al. (1996) Lessons from hereditary colorectal cancer. Cell, 87, 159-170.
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
-
7
-
-
0034644526
-
Linking colorectal cancer to Wnt signaling
-
Bienz,M. et al. (2000) Linking colorectal cancer to Wnt signaling. Cell, 103, 311-320.
-
(2000)
Cell
, vol.103
, pp. 311-320
-
-
Bienz, M.1
-
8
-
-
0036174452
-
Beta-catenin - a linchpin in colorectal carcinogenesis?
-
Wong,N.A. et al. (2002) Beta-catenin - a linchpin in colorectal carcinogenesis? Am. J. Pathol., 160, 389-401.
-
(2002)
Am. J. Pathol
, vol.160
, pp. 389-401
-
-
Wong, N.A.1
-
9
-
-
1542347695
-
Convergence of Wnt, beta-catenin, and cadherin pathways
-
Nelson,W.J. et al. (2004) Convergence of Wnt, beta-catenin, and cadherin pathways. Science, 303, 1483-1487.
-
(2004)
Science
, vol.303
, pp. 1483-1487
-
-
Nelson, W.J.1
-
10
-
-
13044281685
-
Target genes of beta-catenin-T cell-factor/ lymphoid-enhancer-factor signaling in human colorectal carcinomas
-
Mann,B. et al. (1999) Target genes of beta-catenin-T cell-factor/ lymphoid-enhancer-factor signaling in human colorectal carcinomas. Proc. Natl. Acad. Sci. USA, 96, 1603-1608.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 1603-1608
-
-
Mann, B.1
-
11
-
-
17244376814
-
Wnt signalling in stem cells and cancer
-
Reya,T. et al. (2005) Wnt signalling in stem cells and cancer. Nature, 434, 843-850.
-
(2005)
Nature
, vol.434
, pp. 843-850
-
-
Reya, T.1
-
12
-
-
0038783316
-
Secreted antagonists of the Wnt signalling pathway
-
Kawano,Y. et al. (2003) Secreted antagonists of the Wnt signalling pathway. J. Cell Sci., 116, 2627-2634.
-
(2003)
J. Cell Sci
, vol.116
, pp. 2627-2634
-
-
Kawano, Y.1
-
13
-
-
0036714307
-
Secreted frizzled-related proteins: Searching for relationships and patterns
-
Jones,S.E. et al. (2002) Secreted frizzled-related proteins: searching for relationships and patterns. Bioessays, 24, 811-820.
-
(2002)
Bioessays
, vol.24
, pp. 811-820
-
-
Jones, S.E.1
-
14
-
-
0031808517
-
Evaluation of mouse Sfrp3/Frzb1 as a candidate for the 1st, Ul, and Far mutants on chromosome 2
-
Peichel,C.L. et al. (1998) Evaluation of mouse Sfrp3/Frzb1 as a candidate for the 1st, Ul, and Far mutants on chromosome 2. Mamm. Genome, 9, 385-387.
-
(1998)
Mamm. Genome
, vol.9
, pp. 385-387
-
-
Peichel, C.L.1
-
15
-
-
2642670285
-
Chromosomal aberrations associated with invasion in papillary superficial bladder cancer
-
Simon,R. et al. (1998) Chromosomal aberrations associated with invasion in papillary superficial bladder cancer. J. Pathol., 185, 345-351.
-
(1998)
J. Pathol
, vol.185
, pp. 345-351
-
-
Simon, R.1
-
16
-
-
0027960585
-
Frequent allelic losses on chromosomes 2q, 18q, and 22q in advanced non-small cell lung carcinoma
-
Shiseki,M. et al. (1994) Frequent allelic losses on chromosomes 2q, 18q, and 22q in advanced non-small cell lung carcinoma. Cancer Res., 54, 5643-5648.
-
(1994)
Cancer Res
, vol.54
, pp. 5643-5648
-
-
Shiseki, M.1
-
17
-
-
0036165075
-
Hypermethylation of the inhibin alpha-subunit gene in prostate carcinoma
-
Schmitt,J.F. et al. (2002) Hypermethylation of the inhibin alpha-subunit gene in prostate carcinoma. Mol. Endocrinol., 16 213-220.
-
(2002)
Mol. Endocrinol
, vol.16
, pp. 213-220
-
-
Schmitt, J.F.1
-
18
-
-
0031802499
-
Loss of heterozygosity during the development and progression of differentiated adenocarcinoma of the stomach
-
Nishizuka,S. et al. (1998) Loss of heterozygosity during the development and progression of differentiated adenocarcinoma of the stomach. J. Pathol., 185, 38-43.
-
(1998)
J. Pathol
, vol.185
, pp. 38-43
-
-
Nishizuka, S.1
-
19
-
-
0031806636
-
Loss of heterozygosity on chromosome 2q: Possibly a poor prognostic factor in head and neck cancer
-
Ransom,D.T. et al. (1998) Loss of heterozygosity on chromosome 2q: possibly a poor prognostic factor in head and neck cancer. Head Neck 20, 404-410.
-
(1998)
Head Neck
, vol.20
, pp. 404-410
-
-
Ransom, D.T.1
-
20
-
-
0030933978
-
Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer
-
Leyns,L. et al. (1997) Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer. Cell, 88, 747-756.
-
(1997)
Cell
, vol.88
, pp. 747-756
-
-
Leyns, L.1
-
21
-
-
2342574321
-
Deletions of chromosome 8p and loss of sFRP1 expression are progression markers of papillary bladder cancer
-
Stoehr,R. et al. (2004) Deletions of chromosome 8p and loss of sFRP1 expression are progression markers of papillary bladder cancer. Lab. Invest., 84, 465-478.
-
(2004)
Lab. Invest
, vol.84
, pp. 465-478
-
-
Stoehr, R.1
-
22
-
-
12144291274
-
Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer
-
Suzuki,H. et al. (2004) Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer. Nat. Genet. 36, 417-422.
-
(2004)
Nat. Genet
, vol.36
, pp. 417-422
-
-
Suzuki, H.1
-
23
-
-
4444343396
-
Expression of the secreted frizzled-related protein gene family is downregulated in human mesothelioma
-
Lee,A.Y. et al. (2004) Expression of the secreted frizzled-related protein gene family is downregulated in human mesothelioma. Oncogene 23, 6672-6676.
-
(2004)
Oncogene
, vol.23
, pp. 6672-6676
-
-
Lee, A.Y.1
-
24
-
-
0036613250
-
A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer
-
Suzuki,H. et al. (2002) A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer. Nat. Genet., 31, 141-149.
-
(2002)
Nat. Genet
, vol.31
, pp. 141-149
-
-
Suzuki, H.1
-
25
-
-
13644251086
-
Loss of SFRP1 is associated with breast cancer progression and poor prognosis in early stage tumors
-
Klopocki,E. et al. (2004) Loss of SFRP1 is associated with breast cancer progression and poor prognosis in early stage tumors. Int. J. Oncol., 25, 641-649.
-
(2004)
Int. J. Oncol
, vol.25
, pp. 641-649
-
-
Klopocki, E.1
-
26
-
-
0035855667
-
WNT pathway and mammary carcinogenesis: Loss of expression of candidate tumor suppressor gene SFRP1 in most. invasive carcinomas except of the medullary type
-
Ugolini,F. et al. (2001) WNT pathway and mammary carcinogenesis: loss of expression of candidate tumor suppressor gene SFRP1 in most. invasive carcinomas except of the medullary type. Oncogene; 20 5810-5817.
-
(2001)
Oncogene
, vol.20
, pp. 5810-5817
-
-
Ugolini, F.1
-
27
-
-
27544496133
-
Expression of Frzb/secreted frizzled-related protein 3, a secreted Wnt antagonist, in human androgen-independent prostate cancer PC-3 cells suppresses tumor growth and cellular invasiveness
-
Zi,X. et al. (2005) Expression of Frzb/secreted frizzled-related protein 3, a secreted Wnt antagonist, in human androgen-independent prostate cancer PC-3 cells suppresses tumor growth and cellular invasiveness. Cancer Res., 65, 9762-9770.
-
(2005)
Cancer Res
, vol.65
, pp. 9762-9770
-
-
Zi, X.1
-
28
-
-
33746129686
-
Does a negative screening colonoscopy ever need to be repeated?
-
Brenner,H. et al. (2006) Does a negative screening colonoscopy ever need to be repeated? Gut, 55, 1145-1150.
-
(2006)
Gut
, vol.55
, pp. 1145-1150
-
-
Brenner, H.1
-
29
-
-
33749253716
-
ARLTS1 variants and risk of colorectal cancer
-
Frank,B. et al. (2006) ARLTS1 variants and risk of colorectal cancer. Cancer Lett., 244, 172-175.
-
(2006)
Cancer Lett
, vol.244
, pp. 172-175
-
-
Frank, B.1
-
30
-
-
33750529518
-
Death receptor 4 variants and colorectal cancer risk
-
Frank,B. et al. (2006) Death receptor 4 variants and colorectal cancer risk. Cancer Epidemiol. Biomarkers Prev., 15, 2002-2005.
-
(2006)
Cancer Epidemiol. Biomarkers Prev
, vol.15
, pp. 2002-2005
-
-
Frank, B.1
-
31
-
-
0030799081
-
The cysteine-rich frizzled domain of Frzb-1 is required and sufficient for modulation of Wnt signaling
-
Lin,K. et al. (1997) The cysteine-rich frizzled domain of Frzb-1 is required and sufficient for modulation of Wnt signaling. Proc. Natl. Acad. Sci. USA, 94, 11196-11200.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 11196-11200
-
-
Lin, K.1
-
32
-
-
0037085393
-
Disulfide bond assignments of secreted frizzled-related protein-1 provide insights about frizzled homology and netrin modules
-
Chong,J.M. et al. (2002) Disulfide bond assignments of secreted frizzled-related protein-1 provide insights about frizzled homology and netrin modules. J. Biol. Chem., 277, 5134-5144.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 5134-5144
-
-
Chong, J.M.1
-
33
-
-
0039174251
-
Secreted frizzled-related protein-1 binds directly to Wingless and is a biphasic modulator of Wnt signaling
-
Uren,A. et al. (2000) Secreted frizzled-related protein-1 binds directly to Wingless and is a biphasic modulator of Wnt signaling. J. Biol. Chem., 275, 4374-4382.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 4374-4382
-
-
Uren, A.1
-
34
-
-
3042709473
-
Functional variants within the secreted frizzled-related protein 3 gene are associated with hip osteoarthritis in females
-
Loughlin,J. et al. (2004) Functional variants within the secreted frizzled-related protein 3 gene are associated with hip osteoarthritis in females. Proc. Natl. Acad. Sci. USA, 101, 9757-9762.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 9757-9762
-
-
Loughlin, J.1
-
35
-
-
33644850767
-
Association of the CASP10 V410I variant with reduced familial breast cancer risk and interaction with the CASP8 D302H variant
-
Frank,B. et al. (2006) Association of the CASP10 V410I variant with reduced familial breast cancer risk and interaction with the CASP8 D302H variant. Carcinogenesis, 27, 606-609.
-
(2006)
Carcinogenesis
, vol.27
, pp. 606-609
-
-
Frank, B.1
-
36
-
-
33747894213
-
Interaction of Werner and Bloom syndrome genes with p53 in familial breast cancer
-
Wirtenberger,M. et al. (2006) Interaction of Werner and Bloom syndrome genes with p53 in familial breast cancer. Carcinogenesis, 27, 1655-1660.
-
(2006)
Carcinogenesis
, vol.27
, pp. 1655-1660
-
-
Wirtenberger, M.1
-
37
-
-
33750465890
-
Associations of genetic variants in the estrogen receptor coactivators PPARGC1A, PPARGC1B and EP300 with familial breast cancer
-
Wirtenberger,M. et al. (2006) Associations of genetic variants in the estrogen receptor coactivators PPARGC1A, PPARGC1B and EP300 with familial breast cancer. Carcinogenesis, 27, 2201-2208.
-
(2006)
Carcinogenesis
, vol.27
, pp. 2201-2208
-
-
Wirtenberger, M.1
-
38
-
-
11144355390
-
Illegitimate WNT signaling promotes proliferation of multiple myeloma cells
-
Derksen,P.W. et al. (2004) Illegitimate WNT signaling promotes proliferation of multiple myeloma cells. Proc. Natl. Acad. Sci. USA 101, 6122-6127.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 6122-6127
-
-
Derksen, P.W.1
-
39
-
-
0037442760
-
Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis
-
Gunther,E.J. et al. (2003) Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis. Genes Dev., 17, 488-501.
-
(2003)
Genes Dev
, vol.17
, pp. 488-501
-
-
Gunther, E.J.1
-
40
-
-
0037704269
-
Proof-of-principle: Oncogenic beta-catenin is a valid molecular target for the development of pharmacological inhibitors
-
Kim,J.S. et al. (2002) Proof-of-principle: Oncogenic beta-catenin is a valid molecular target for the development of pharmacological inhibitors. Mol. Cancer Ther., 1, 1355-1359.
-
(2002)
Mol. Cancer Ther
, vol.1
, pp. 1355-1359
-
-
Kim, J.S.1
-
41
-
-
4344584730
-
WNT and beta-catenin signalling: Diseases and therapies
-
Moon,R.T. et al. (2004) WNT and beta-catenin signalling: Diseases and therapies. Nat. Rev. Genet., 5, 691-701.
-
(2004)
Nat. Rev. Genet
, vol.5
, pp. 691-701
-
-
Moon, R.T.1
|