Association of the CASP10 V410I variant with reduced familial breast cancer risk and interaction with the CASP8 D302H variant

Carcinogenesis

Volumn 27, Issue 3, 2006, Pages 606-609

  Frank, Bernd ^a   Hemminki, Kari ^a,b   Wappenschmidt, Barbara ^c,d   Meindl, Alfons ^e   Klaes, Rüdiger ^f   Schmutzler, Rita K ^c,d   Bugert, Peter ^f   Untch, Michael ^g   Bartram, Claus R ^f   Burwinkel, Barbara ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY OF COLOGNE   (Germany)

^d UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^e TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^f UNIVERSITY OF HEIDELBERG   (Germany)

^g UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 10; CASPASE 8;

ADULT; AGED; ALLELE; APOPTOSIS; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER GENETICS; CANCER RISK; CASE CONTROL STUDY; CONTROLLED STUDY; FAMILIAL CANCER; FEMALE; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; PROTEIN PROTEIN INTERACTION; RISK REDUCTION; STATISTICAL ANALYSIS;

ADULT; AGED; AGED, 80 AND OVER; APOPTOSIS; BREAST NEOPLASMS; CASE-CONTROL STUDIES; CASPASE 10; CASPASE 8; CASPASES; FEMALE; GENES, BRCA1; GENES, BRCA2; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MIDDLE AGED; MITOCHONDRIA; PEDIGREE; POLYMORPHISM, GENETIC;

EID: 33644850767     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgi248     Document Type: Article

References (25)

1. Hengartner,M.O. (2000) The biochemistry of apoptosis. Nature, 407, 770-776.
2. Evan,G.I. and Vousden,K.H. (2001) Proliferation, cell cycle and apoptosis in cancer. Nature, 411, 342-348.
3. Chen,M. and Wang,J. (2002) Initiator caspases in apoptosis signaling pathways. Apoptosis, 7, 313-319.
4. Wang,J., Chun,H.J., Wong,W., Spencer,D.M. and Lenardo,M.J. (2001) Caspase-10 is an initiator caspase in death receptor signaling. Proc. Natl Acad. Sci. USA, 98, 13884-13888.
5. Engels,I.H., Totzke,G., Fischer,U., Schulze-Osthoff,K. and Janicke,R.U. (2005) Caspase-10 sensitizes breast carcinoma cells to TRAIL-induced but not tumor necrosis factor-induced apoptosis in a caspase-3-dependent manner. Mol. Cell. Biol., 25, 2808-2818.
6. McDonald,E.R.III and El-Deiry,W.S. (2004) Suppression of caspase-8-and -10-associated RING proteins results in sensitization to death ligands and inhibition of tumor cell growth. Proc. Natl Acad. Sci. USA, 101, 6170-6175.
7. Milhas,D., Cuvillier, O., Therville,N., Clave,P., Thomsen,M., Levade,T., Benoist,H. and Segui,B. (2005) Caspase-10 triggers bid cleavage and caspase cascade activation in FasL-induced apoptosis. J. Mol. Chem., 280, 19836-19842.
8. Ashkenazi,A. (2002) Targeting death and decoy receptors of the tumour-necrosis factor superfamily. Nat. Rev. Cancer, 2, 420-430.
9. MacPherson,G., Healey,C.S., Teare,M.D., Balasubramanian,S.P., Reed,M.W., Pharoah,P.D., Ponder,B.A., Meuth,M., Bhattacharyya,N.P. and Cox,A. (2004) Association of a common variant of the CASP8 gene with reduced risk of breast cancer. J. Natl Cancer Inst., 96, 1866-1869.
10. Frank,B., Bermejo,J.L., Hemminki,K., Klaes,R., Bugert,P., Wappenschmidt,B., Schmutzler,R.K. and Burwinkel,B. (2005) Re: association of a common variant of the CASP8 gene with reduced risk of breast cancer. J. Natl Cancer Inst., 97, 1012.
11. Meindl,A. and the German Consortium for Hereditary Breast and Ovarian Cancer. (2002) Comprehensive analysis of 989 patients with breast or ovarian cancer provides BRCA1 and BRCA2 mutation profiles and frequencies for the German population. Int. J. Cancer, 97, 472-480.
12. Frank,B., Hemminki,K., Wirtenberger,M., Bermejo,J.L., Bugert,P., Klaes,R., Schmutzler,R.K., Wappenschmidt,B., Bartram,C.R. and Burwinkel,B. (2005) The rare ERBB2 variant Ile654Val is associated with an increased familial breast cancer risk. Carcinogenesis, 26, 643-647.
13. Cannings,C. and Edwards,A.W. (1968) Natural selection and the de Finetti diagram. Ann. Hum. Genet., 31, 421-428.
14. Mendell,N.R. and Simon,G.A. (1984) A general expression for the variance-covariance matrix of estimates of gene frequency: The effects of departures from Hardy-Weinberg equilibrium. Ann. Hum. Genet., 48, 283-286.
15. Sasieni,P.D. (1997) From genotypes to genes: Doubling the sample size. Biometrics, 53, 1253-1261.
16. Cohen,G.M. (1997) Caspases: The executioners of apoptosis. Biochem. J., 326, 1-16.
17. Alcivar,A., Hu,S., Tang,J. and Yang,X. (2003) DEDD and DEDD2 associate with caspase-8/10 and signal cell death. Oncogene, 22,291-297.
18. Inohara,N., Koseki,T., Hu,Y., Chen,S. and Nunez,G. (1997) CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis. Proc. Natl Acad. Sci. USA, 94, 10717-10722.
19. Barnhart,B.C., Lee,J.C., Alappat,E.C. and Peter,M.E. (2003) The death effector domain protein family. Oncogene, 22, 8634-8644.
20. Park,W.S., Lee,J.H., Shin,M.S. et al. (2002) Inactivating mutations of the caspase-10 gene in gastric cancer. Oncogene, 21, 2919-2925.
21. Hemminki,K. and Forsti,A. (2002) Controls need to be selected for the type of SNP study. Carcinogenesis, 23, 2137.
22. Brennan,P. and Boffetta,P. (2002) Proper controls for SNP studies? Carcinogenesis, 23, 2139.
23. Houlston,R.S. and Peto,J. (2003) The future of association studies of common cancers. Hum. Genet., 112, 434-435.
24. Antoniou,A.C. and Easton,D.F. (2003) Polygenic inheritance of breast cancer: Implications for design of association studies. Genet. Epidemiol., 25, 190-202.
25. Dupont,W.D. and Plummer,W.D. Jr (1998) Power and sample size calculations for studies involving linear regression. Control. Clin. Trials., 19, 589-601.