Loss of heterozygosity during the development and progression of differentiated adenocarcinoma of the stomach

Journal of Pathology

Volumn 185, Issue 1, 1998, Pages 38-43

  Nishizuka, Satoshi ^a   Tamura, Gen ^a   Terashima, Masanori ^a   Satodate, Ryoichi ^a  

^a IWATE MEDICAL UNIVERSITY   (Japan)

Author keywords

Adenocarcinoma of the stomach; Fractional allelic loss; Loss of heterozygosity; Microsatellite analysis; Multistep carcinogenesis

Indexed keywords

DNA;

ADVANCED CANCER; ARTICLE; CHROMOSOME 11Q; CHROMOSOME 14Q; CHROMOSOME 17P; CHROMOSOME 18Q; CHROMOSOME 21Q; CHROMOSOME 2Q; CHROMOSOME 4P; CHROMOSOME 5Q; CHROMOSOME 6P; CHROMOSOME 7Q; CONTROLLED STUDY; EARLY CANCER; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; STOMACH ADENOCARCINOMA; STOMACH CARCINOGENESIS; TUMOR DIFFERENTIATION;

ADENOCARCINOMA; CELL TRANSFORMATION, NEOPLASTIC; DISEASE PROGRESSION; HUMANS; LOSS OF HETEROZYGOSITY; MICROSATELLITE REPEATS; POLYMERASE CHAIN REACTION; STOMACH NEOPLASMS;

EID: 0031802499     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(199805)185:1<38::AID-PATH58>3.0.CO;2-T     Document Type: Article

References (36)

1. Ezaki T, Yanagisawa A, Ohta K, et al. Deletion mapping on chromosome 1p in well-differentiated gastric cancer. Br J Cancer 1996; 73: 424-428.
2. Sano T, Tsujino T, Yoshida K, et al. Frequent loss of heterozygosity on chromosomes 1q, 5q, and 17p in human gastric carcinomas. Cancer Res 1991; 51: 2926-2931.
3. Schneider BG, Pulitzer DR, Brown RD, et al. Allelic imbalance in gastric cancer: an affected site on chromosome arm 3p. Genes Chromosom Cancer 1995; 13: 263-271.
4. Kuniyasu H, Yasui W, Yokozaki H, et al. Frequent loss of heterozygosity of the long arm of chromosome 7 is closely associated with progression of human gastric carcinomas. Int J Cancer 1994; 59: 597-600.
5. Baffa R, Negrini M, Mandes B, et al. Loss of heterozygosity for chromosome 11 in adenocarcinoma of the stomach. Cancer Res 1996; 56: 268-272.
6. Uchino S, Tsuda H, Noguchi M, et al. Frequent loss of heterozygosity at the DCC locus in gastric cancer. Cancer Res 1992; 52: 3099-3102.
7. Tamura G, Kihana T, Nomura K, Terada M, Sugimura T, Hirohashi S. Detection of frequent p53 gene mutations in primary gastric cancer by cell sorting and polymerase chain reaction single-strand conformation polymorphism analysis. Cancer Res 1991; 51: 3056-3058.
8. Tamura G, Sakata K, Nishizuka S, et al. Allelotype of adenoma and differentiated adenocarcinoma of the stomach. J Pathol 1996; 180: 371-377.
9. Sambrook J, Fritsch EF, Maniatis T. Molecular Cloning: A Laboratory Manual. 2nd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1989.
10. Vogelstein B, Fearon ER, Hamilton SR, et al. Genetic alterations during colorectal-tumor development. N Engl J Med 1988; 319: 525-532.
11. Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990; 61: 759-767.
12. Tamura G, Maesawa C, Suzuki Y, et al. Mutations of the APC gene occur during early stages of gastric adenoma development. Cancer Res 1994; 54: 1149-1151.
13. Maesawa C, Tamura G, Suzuki Y, et al. The sequential accumulation of genetic alterations characteristic of the colorectal adenoma-carcinoma sequence does not occur between gastric adenoma and adenocarcinoma. J Pathol 1995; 176: 249-258.
14. Tamura G. Molecular pathogenesis of adenoma and differentiated adenocarcinoma of the stomach. Pathol Int 1996; 46: 834-841.
15. Zenklusen JC, Thompson JC, Klein-Szanlo AJP, Conti CJ. Frequent loss of heterozygosity in human primary squamous cell and colon carcinomas at 7q31.1: evidence for a broad range tumor suppressor gene. Cancer Res 1995; 55: 1347-1350.
16. Zenklusen JC, Weitzel JN, Ball HG, Conti CJ. Allelic loss at 7g31.1 in human primary ovarian carcinomas suggests the existence of a tumor suppressor gene. Oncogene 1995; 11: 359-363.
17. Nishizuka S, Tamura G, Terashima M, Satodate R. Commonly deleted region on the long arm of chromosome 7 in differentiated adenocarcinoma of the stomach. Br J Cancer 1997; 76: 1567-1571.
18. Shiao Y-H, Rugge M, Correa P, Lehmann HP, Scheer WD. p53 alteration in gastric precancerous lesions. Am J Pathol 1994; 144: 511-517.
19. Tamura G, Sakata K, Maesawa C, et al. Microsatellite alterations in adenoma and differentiated adenocarcinoma of the stomach. Canter Res 1995; 55: 1933-1936.
20. Sakata K, Tamura G, Nishizuka S, et al. Commonly deleted regions on the long arm of chromosome 21 in differentiated adenocarcinoma of the stomach. Genes Chromosom Cancer 1997; 18: 318-321.
21. Kohno T, Otsuka T, Takano H, et al. Identification of a novel phospholipase C family gene at chromosome 2q33 that is homozygously deleted in human small cell lung carcinoma. Hum Mol Genet 1995; 4: 667-674.
22. Kinzler KW, Nilbert MC, Su L-K, et al. Identification of FAP locus genes from chromosome 5q21. Science 1991; 253: 661-665.
23. El-Deiry WS, Tokino T, Velculescu VE, et al. WAF1, a potential mediator of p53 tumor suppression. Cell 1993; 75: 817-825.
24. Savitsky K, Bar-Shira A, Gilad S, et al. A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science 1995; 268: 1749-1753.
25. Fearon ER, Cho KR, Nigro JM, et al. Identification of a chromosome 18q gene that is altered in colorectal cancers. Science 1990; 247: 49-56.
26. Shiseki M, Kohno T, Adachi J, et al. Comparative allelotype of early and advanced stage non-small cell lung carcinomas. Genes Chromosom Cancer 1996; 17: 71-77.
27. Shiohara M, El-Deiry WS, Wada M, et al. Absence of WAF1 mutations in a variety of human malignancies. Blood 1994; 84: 3781-3784.
28. Swift M, Morrell D, Massey RB, Chase CL. Incidence of cancer in 161 families affected by ataxia-telangiectasia. N Engl J Med 1991; 325: 1831-1836.
29. Rhyu M-G, Park W-S, Jung Y-J, Choi S-W, Meltzer SJ. Allelic deletions of MCC/APC and p53 are frequent late events in human gastric carcinogenesis. Gastroenterology 1994; 106: 1584-1588.
30. Tamura G, Ogasawara S, Nishizuka S, et al. Two distinct regions of deletion on the long arm of chromosome 5 in differentiated adenocarcinomas of the stomach. Cancer Res 1996; 56: 612-615.
31. Willman CL, Sever CE, Pallavicini MG, et al. Deletion of IRF-1, mapping to chromosome 5q31.1, in human leukemia and preleukemic myelodysplasia. Science 1993; 259: 968-971.
32. Nishizuka S, Tamura G, Maesawa C, et al. Analysis of the DPC4 gene in gastric carcinoma. Jpn J Cancer Res 1997; 88: 335-339.
33. Schutte M, Hruban RH, Hedrick L, et al. DPC4 gene in various tumor types. Cancer Res 1996; 56: 2527-2530.
34. Vogelstein B, Fearon ER, Kern SE, et al. Allelotype of colorectal carcinomas. Science 1989; 244: 207-211.
35. Radford DM, Fair KL, Phillips NJ, et al. Allelotyping of ductal carcinoma in situ of the breast: deletion of loci on 8p, 13q, 16q, 17p and 17q. Cancer Res 1995; 55: 3399-3405.
36. Barrett MT, Galipeau PC, Sanchez CA, Emond MJ, Reid BJ. Determination of the frequency of loss of heterozygosity in esophageal adenocarcinoma by cell sorting, whole genome amplification and microsatellite polymorphisms. Oncogene 1996; 12: 1873-1878.