Global Child Health: Burden of Disease, Achievements, and Future Challenges

Current Problems in Pediatric and Adolescent Health Care

Volumn 37, Issue 9, 2007, Pages 338-362

  Rosenberg, Melanie ^a  

^a CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; AMPICILLIN; ANTIBIOTIC AGENT; ANTIMALARIAL AGENT; ANTIRETROVIRUS AGENT; ARTEMISIN DERIVATIVE; BCG VACCINE; CHLOROQUINE; CIPROFLOXACIN; COTRIMOXAZOLE; DIPHTHERIA PERTUSSIS TETANUS VACCINE; DIPHTHERIA VACCINE; FANSIDAR; HAEMOPHILUS INFLUENZAE TYPE B VACCINE; HEPATITIS B VACCINE; INSECTICIDE; LAMIVUDINE PLUS ZIDOVUDINE; MALARIA VACCINE; MEASLES VACCINE; NEVIRAPINE; PENICILLIN G; PERTUSSIS VACCINE; PNEUMOCOCCUS VACCINE; POLIOMYELITIS VACCINE; RETINOL; ROTAVIRUS VACCINE; TETANUS TOXOID; TETRACYCLINE; UNINDEXED DRUG; ZIDOVUDINE;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL MENINGITIS; BED NET; CAUSE OF DEATH; CHILD HEALTH CARE; CHILDHOOD MORTALITY; CLINICAL TRIAL; COGNITIVE DEFECT; CROWDING; DEHYDRATION; DEVELOPING COUNTRY; DIARRHEA; DIPHTHERIA; DRUG COST; DRUG EFFICACY; DRUG INTERMITTENT THERAPY; DRUG SAFETY; DYSENTERY; GEOGRAPHY; HEALTH CARE ACCESS; HEALTH CARE COST; HEPATITIS B; HIGH RISK POPULATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INCIDENCE; MALARIA; MALNUTRITION; MATERNAL WELFARE; MEASLES; MORBIDITY; NEWBORN MORBIDITY; NEWBORN MORTALITY; NEWBORN TETANUS; ORAL REHYDRATION THERAPY; PARASITOSIS; PERTUSSIS; PHYSICAL EXAMINATION; PNEUMONIA; POLIOMYELITIS; PREVALENCE; PRIMARY PREVENTION; REHYDRATION; RISK FACTOR; SANITATION; SHIGELLOSIS; SINGLE DRUG DOSE; THORAX RADIOGRAPHY; TUBERCULOSIS; VACCINATION; VIRUS TRANSMISSION; VITAMIN SUPPLEMENTATION;

ADOLESCENT; CHILD; CHILD MORTALITY; CHILD NUTRITION DISORDERS; CHILD WELFARE; CHILD, PRESCHOOL; COGNITION DISORDERS; COMMUNICABLE DISEASES; COST OF ILLNESS; DEVELOPING COUNTRIES; HEALTH STATUS; HUMANS; INFANT; INFANT MORTALITY; INFANT, NEWBORN; MATERNAL WELFARE; MORBIDITY; PARASITIC DISEASES; WORLD HEALTH;

EID: 34748904088     PISSN: 15385442     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cppeds.2007.07.003     Document Type: Article

References (166)

1. Black R.E., Morris S.S., and Bryce J. Where and why are 10 million children dying every year?. Lancet 361 (2003) 2226-2234
2. United Nations. General assembly, 56th session. Road map towards the implementation of the United Nations millennium declaration: report of the Secretary-General (UN document no. A/56/326) (2001), United Nations, New York. http://www.un.org/documents/ga/docs/56/a56326.pdf [cited June 20, 2007]. Available from: http://www.un.org/documents/ga/docs/56/a56326.pdf.
3. WHO. The World Health Report 2005: Making Every Mother and Child Count (2005), WHO, Geneva. http://www.who.int/whr/2005/en/ [cited April 27, 2007]. Available from: http://www.who.int/whr/2005/en/.
4. UNICEF. Progress for Children. A Child Survival Report Card. Vol 1. New York: UNICEF, 2004 [cited May 2, 2007]. Available from: http://www.unicef.org/publications/index_23557.html.
5. Victora C.G., Wagstaff A., Schellenberg J.A., Gwatkin D., Claeson M., and Habicht J.P. Applying an equity lens to child health and mortality: more of the same is not enough. Lancet 362 (2003) 233-241
6. Caulfield L.E., de Onis M., Blossner M., and Black R.E. Undernutrition as an underlying cause of child deaths associated with diarrhea, pneumonia, malaria, and measles. Am J Clin Nutr 80 (2004) 193-198
7. Kosek M., Bern C., and Guerrant R.L. The global burden of diarrhoeal disease, as estimated from studies published between 1992 and 2000. Bull World Health Organ 81 (2003) 197-204
8. Glass R.I., Parashar U.D., Bresee J.S., Turcios R., Fischer T.K., Widdowson M.A., et al. Rotavirus vaccines: current prospects and future challenges. Lancet 368 (2006) 323-332
9. Podewils L.J., Mintz E.D., Nataro J.P., and Parashar U.D. Acute, infectious diarrhea among children in developing countries. Semin Pediatr Infect Dis 15 (2004) 155-168
10. Parashar U.D., Hummelman E.G., Bresee J.S., Miller M.A., and Glass R.I. Global illness and deaths caused by rotavirus disease in children. Emerg Infect Dis 9 (2003) 565-572
11. Hart C.A., Cunliffe N.A., and Bresee J.S. Diarrhoea caused by viruses. In: Cook G.C., and Zumla A. (Eds). Manson's tropical diseases. 21st Edition (2003), Elsevier Science, London 823-830
12. Cheng A.C., McDonald J.R., and Thielman N.M. Infectious diarrhea in developed and developing countries. J Clin Gastroenterol 39 (2005) 757-773
13. Kotloff K.L., Winickoff J.P., Ivanoff B., Clemens J.D., Swerdlow D.L., Sansonetti D.J., et al. Global burden of Shigella infections: implications for vaccine development and implementation of control strategies. Bull World Health Organ 77 (1999) 651-666
14. Thapar N., and Sanderson I.R. Diarrhoea in children: an interface between developing and developed countries. Lancet 363 (2004) 641-653
15. Bhutta Z.A. Post-infectious persistent diarrhoea. In: Southall D., Coulter B., Ronald C., Nicholson S., and Parke S. (Eds). International child health care: a practical manual for hospitals worldwide. 1st Edition (2002), BMJ Books, London 283-286
16. Keusch G.T., Fontaine O., Bhargava A., Boschi-Pinto C., Bhutta Z.A., Gotuzzo E., et al. Diarrheal diseases. In: Jamison D.T., Breman J.G., Measham A.R., Alleyne G., Claeson M., Evans D.B., et al. (Eds). Disease control priorities in developing countries. 2nd Edition (2006), Oxford University Press, New York 371-388. http://www.dcp2.org/pubs/DCP [cited May 10, 2007]. Available from: http://www.dcp2.org/pubs/DCP.
17. Sentongo T.A. The use of oral rehydration solutions in children and adults. Curr Gastroenterol Rep 6 (2004) 307-313
18. Victora C.G., Bryce J., Fontaine O., and Monasch R. Reducing deaths from diarrhoea through oral rehydration therapy. Bull World Health Organ 78 (2000) 1246-1255
19. WHO. Implementing the new recommendations on the clinical management of diarrhea: guidelines for policy makers and programme managers (2006), WHO, Geneva. http://www.who.int/child-adolescent-health/publications/CHILD_HEALTH/ISBN_92_4_159421_7.htm [cited May 22, 2007]. Available from: http://www.who.int/child-adolescent-health/publications/CHILD_HEALTH/ISBN_92_4_159421_7.htm.
20. Hahn S., Kim Y., and Garner P. Reduced osmolarity oral rehydration solution for treating dehydration due to diarrhoea in children: systematic review. BMJ 323 (2001) 81-85
21. Salam M.A., and Bennish M.L. Antimicrobial therapy for shigellosis. Rev Infect Dis 13 Suppl 4 (1991) S332-S341
22. Niyogi S.K. Shigellosis. J Microbiol 43 (2005) 133-143
23. UNICEF. Pneumonia: The Forgotten Killer of Children (2006), UNICEF, New York. http://childinfo.org/areas/ari/ [updated September 2006; cited 2007 April 25]. Available from: http://childinfo.org/areas/ari/.
24. Cashat-Cruz M., Morales-Aguirre J.J., and Mendoza-Azpiri M. Respiratory tract infections in children in developing countries. Semin Pediatr Infect Dis 16 (2005) 84-92
25. Schuchat A., and Dowell S.F. Pneumonia in children in the developing world: new challenges, new solutions. Semin Pediatr Infect Dis 15 (2004) 181-189
26. Simoes E.A.F., Cherian T., Chow J., Shahid-Salles S., Laxminarayan R., and John T.J. Acute respiratory infections in children. In: Jamison D.T., Breman J.G., Measham A.R., Alleyne G., Claeson M., Evans D.B., et al. (Eds). Disease control priorities in developing countries. 2nd Edition (2006), Oxford University Press, New York 483-497. http://www.dcp2.org/pubs/DCP [cited 2007 May 10]. Available from: http://www.dcp2.org/pubs/DCP.
27. Sazawal S., and Black R.E. Effect of pneumonia case management on mortality in neonates, infants, and preschool children: a meta-analysis of community-based trials. Lancet Infect Dis 3 (2003) 547-556
28. WHO. Technical updates of the guidelines on Integrated Management of Childhood Illness (IMCI): evidence and recommendations for further adaptations (2005), WHO, Geneva. http://www.who.int/child-adolescent-health/publications/IMCI/ISBN_92_4_159348_2.htm [cited 2007 April 27]. Available from: http://www.who.int/child-adolescent-health/publications/IMCI/ISBN_92_4_159348_2.htm.
29. Addo-Yobo E., Chisaka N., Hassan M., Hibberd P., Lozano J.M., Jeena P., et al. Oral amoxicillin versus injectable penicillin for severe pneumonia in children aged 3 to 59 months: a randomised multicentre equivalency study. Lancet 364 (2004) 1141-1148
30. WHO. WHO vaccine-preventable diseases: monitoring system. 2006 Global Summary (2006), WHO, Geneva. http://www.who.int/vaccines-documents/DocsPDF05/WHO_IVB_2005.pdf [cited 2007 April 25]. Available from: http://www.who.int/vaccines-documents/DocsPDF05/WHO_IVB_2005.pdf.
31. Brenzel L., Wolfson L., Fox-Rushby J., Miller M.A., and Halsey N.A. Vaccine-preventable diseases. In: Jamison D.T., Breman J.G., Measham A.R., Alleyne G., Claeson M., Evans D.B., et al. (Eds). Priorities in developing countries. 2nd Edition (2006), Oxford University Press, New York 389-411. http://www.dcp2.org/pubs/DCP [cited 2007 May 10]. Available at: http://www.dcp2.org/pubs/DCP.
32. Perry R.T., and Halsey N.A. The clinical significance of measles: a review. J Infect Dis 189 Suppl 1 (2004) S4-S16
33. WHO. Global Immunization Data (2004), WHO, Geneva. http://www.who.int/immunization_monitoring/data/GlobalImmunizationData.pdf [cited 2007 April 25]. Available from: http://www.who.int/immunization_monitoring/data/GlobalImmunizationData.pdf.
34. Cook T.M., Protheroe R.T., and Handel J.M. Tetanus: a review of the literature. Br J Anaesth 87 (2001) 477-487
35. Vandelaer J., Birmingham M., Gasse F., Kurian M., Shaw C., and Garnier S. Tetanus in developing countries: an update on the maternal and neonatal tetanus elimination initiative. Vaccine 21 (2003) 3442-3445
36. Centers for Disease Control (CDC). Vaccine preventable deaths and the Global Immunization Vision and Strategy, 2006-2015. MMWR Morb Mortal Wkly Rep 55 (2006) 511-515
37. WHO. Progress towards Global Immunization Goals - 2005: Summary presentation of key indicators. Geneva, 2006 [cited 2007 May 19]. Available from: http://www.who.int/immunization_monitoring/data/SlidesGlobalImmunization.pdf.
38. World Health Organization (WHO). Measles Vaccines. WHO Position Paper. Wkly Epidemiolog Rec 79 (2004) 130-143
39. Wolfson L.J., Strebel P.M., Gacic-Dobo M., Hoekstra E.J., McFarland J.W., and Hersh B.S. Has the 2005 measles mortality reduction goal been achieved?. A natural history modelling study. Lancet 369 (2007) 191-200
40. World Health Organization (WHO). Position Paper on Haemophilus Influenzae type b conjugate vaccines. Wkly Epidemiolog Rec 81 (2006) 445-452
41. Adegbola R.A., Secka O., Lahai G., Lloyd-Evans N., Nije A., Usen S., et al. Elimination of Haemophilus influenzae type b (Hib) disease from The Gambia after the introduction of routine immunisation with a Hib conjugate vaccine: a prospective study. Lancet 366 (2005) 144-150
42. WHO. Selected vaccine introduction status into routine infant immunization worldwide (2003), WHO, Geneva. http://www.who.int/immunization_monitoring/routine/schedule_analysis_2003.pdf [cited 2007 June 20]. Available from: http://www.who.int/immunization_monitoring/routine/schedule_analysis_2003.pdf.
43. WHO. Pneumococcal conjugate vaccine for childhood immunization-WHO position paper. Wkly Epidemiolog Rec 82 (2007) 93-104
44. Cutts F.T., Zaman S.M., Enwere G., Jaffar S., Levine O.S., Okoko J.B., et al. Efficacy of nine-valent pneumococcal conjugate vaccine against pneumonia and invasive pneumococcal disease in The Gambia: randomised, double-blind, placebo-controlled trial. Lancet 365 (2005) 1139-1146
45. Klugman K.P., Madhi S.A., Huebner R.E., Kohberger R., Mbelle N., and Pierce N. A trial of a 9-valent pneumococcal conjugate vaccine in children with and those without HIV infection. N Engl J Med 349 (2003) 1341-1348
46. Vesikari T., Matson D.O., Dennehy P., Van Damme P., Santosham M., Rodriguez Z., et al. Safety and efficacy of a pentavalent human-bovine (WC3) reassortant rotavirus vaccine. N Engl J Med 354 (2006) 23-33
47. Ruiz-Palacios G.M., Perez-Schael I., Velazquez F.R., Abate H., Breuer T., Clemens S.C., et al. Safety and efficacy of an attenuated vaccine against severe rotavirus gastroenteritis. N Engl J Med 354 (2006) 11-22
48. Glass R.I., Bresee J.S., Turcios R., Fischer T.K., Parashar U.D., and Steele A.D. Rotavirus vaccines: targeting the developing world. J Infect Dis 192 Suppl 1 (2005) S160-S166
49. WHO, and NICEF. World Malaria Report 2005 (2005), WHO, Geneva. http://www.rbm.who.int/wmr2005/html/toc.htm [cited 2007 April 27]. Available at: http://www.rbm.who.int/wmr2005/html/toc.htm.
50. Greenwood B.M., Bojang K., Whitty C.J., and Targett G.A. Malaria. Lancet 365 (2005) 1487-1498
51. Summer A.P., Stauffer W.M., and Fischer P.R. Pediatric malaria in the developing world. Semin Pediatr Infect Dis 16 (2005) 105-115
52. Murphy S.C., and Breman J.G. Gaps in the childhood malaria burden in Africa: cerebral malaria, neurological sequelae, anemia, respiratory distress, hypoglycemia, and complications of pregnancy. Am J Trop Med Hyg 64 Suppl 1-2 (2001) 57-67
53. Mung'Ala-Odera V., Snow R.W., and Newton C.R. The burden of the neurocognitive impairment associated with Plasmodium falciparum malaria in sub-saharan Africa. Am J Trop Med Hyg 71 Suppl 2 (2004) 64-70
54. Roll Back Malaria, WHO. Children and Malaria. Roll Back Malaria Information Sheet [cited 2007 June 20]. Available from: http://www.rbm.who.int/cmc_upload/0/000/015/367/RBMInfosheet_6.htm.
55. John CC. Pediatric malaria: defining the problem, devising solutions. Presented at Pediatric Academic Societies' Annual Meeting. Toronto; 2007.
56. Breman J.G., Mills A., Snow R.W., Mulligan J., Lengeler C., Mendis K., et al. Conquering malaria. In: Jamison D.T., Breman J.G., Measham A.R., Alleyne G., Claeson M., Evans D.B., et al. (Eds). Disease control priorities in developing countries. 2nd Edition (2006), Oxford University Press, New York 413-431. http://www.dcp2.org/pubs/DCP [cited 2007 May 19]. Available from: http://www.dcp2.org/pubs/DCP.
57. Lengeler C. Insecticide-treated bed nets and curtains for preventing malaria. Cochrane Database Syst Rev 2 (2004) CD000363.
58. Lengeler C., and Shapr B. Indoor Residual Spraying and Insecticide-treated Nets. Reducing Malaria's Burden: Evidence of Effectiveness for Decision-Makers (2003), Global Health Council, Washington, DC. http://www.globalhealth.org/view_top.php3?id=384 [cited 2007 May 20]. Available from: http://www.globalhealth.org/view_top.php3?id=384.
59. WHO Global Malaria Programme. Indoor residual spraying: Use of indoor residual spraying for scaling up global malaria control and elimination. WHO Position Statement (2006), WHO, Geneva. http://malaria.who.int/docs/IRS-position.pdf [cited 2007 May 20]. Available from: http://malaria.who.int/docs/IRS-position.pdf.
60. WHO. WHO gives indoor use of DDT a clean bill of health for controlling malaria. News release. Washington DC; 2006 [cited 2007 May 20]. Available from: http://www.who.int/mediacentre/news/releases/2006/pr50/en/index.html.
61. Vallely A., Vallely L., Changalucha J., Greenwood B., and Chandramohan D. Intermittent preventive treatment for malaria in pregnancy in Africa: what's new, what's needed?. Malar J 6 (2007) 16
62. Rogerson S.J., Chaluluka E., Kanjala M., Mkundika P., Mhango C., and Molyneux M.E. Intermittent sulfadoxine-pyrimethamine in pregnancy: effectiveness against malaria morbidity in Blantyre. Malawi, in 1997-99. Trans R Soc Trop Med Hyg 94 (2000) 549-553
63. Greenwood B. Review: Intermittent preventive treatment-a new approach to the prevention of malaria in children in areas with seasonal malaria transmission. Trop Med Int Health 11 (2006) 983-991
64. Shetty A.K., and Woods C.R. Prevention of malaria in children. Pediatr Infect Dis J 25 (2006) 1173-1176
65. O'Meara W.P., Breman J.G., and McKenzie F.E. The promise and potential challenges of intermittent preventive treatment for malaria in infants (IPTi). Malar J 4 (2005) 33
66. WHO. Taking Stock: HIV in children (2006), WHO, Geneva. http://www.who.int/hiv/pub/advocacy/children/en/ [cited 2007 May 2]. Available from: http://www.who.int/hiv/pub/advocacy/children/en/.
67. Spira R., Lepage P., Msellati P., Van De Perre P., Leroy V., Simonon A., et al. Natural history of human immunodeficiency virus type 1 infection in children: a five-year prospective study in Rwanda. Mother-to-Child HIV-1 Transmission Study Group. Pediatrics 104 (1999) e56
68. Taha T.E., Graham S.M., Kumwenda N.I., Broadhead R.L., Hoover D.R., Markakis D., et al. Morbidity among human immunodeficiency virus-1-infected and -uninfected African children. Pediatrics 106 (2000) e77
69. Walker N., Schwartlander B., and Bryce J. Meeting international goals in child survival and HIV/AIDS. Lancet 360 (2002) 284-289
70. UNICEF. HIV/AIDS: Preventing Mother to Child Transmission [updated 2006 March; cited 2007 June 20]. Available from: http://childinfo.org/areas/hivaids/mtct.php.
71. De Cock K.M., Fowler M.G., Mercier E., de Vincenzi I., Saba J., Hoff E., et al. Prevention of mother-to-child HIV transmission in resource-poor countries: translating research into policy and practice. JAMA 283 (2000) 1175-1182
72. Brocklehurst P., and Volmink J. Antiretrovirals for reducing the risk of mother-to-child transmission of HIV infection. Cochrane Database Syst Rev 1 (2002) CD003510.
73. Coovadia H.M., Rollins N.C., Bland R.M., Little K., Coutsoudis A., Bennish M.L., et al. Mother-to-child transmission of HIV-1 infection during exclusive breastfeeding in the first 6 months of life: an intervention cohort study. Lancet 369 (2007) 1107-1116
74. Thior I., Lockman S., Smeaton L.M., Shapiro R.L., Wester C., Heymann S.J., et al. Breastfeeding plus infant zidovudine prophylaxis for 6 months vs formula feeding plus infant zidovudine for 1 month to reduce mother-to-child HIV transmission in Botswana: a randomized trial: the Mashi Study. JAMA 296 (2006) 794-805
75. Iliff P.J., Piwoz E.G., Tavengwa N.V., Zunguza C.D., Marinda E.T., Nathoo K.J., et al. Early exclusive breastfeeding reduces the risk of postnatal HIV-1 transmission and increases HIV-free survival. AIDS 19 (2005) 699-708
76. WHO. WHO HIV and Infant Feeding Technical Consultation. Consensus Statement. Held on behalf of the Inter-agency Task Team (IATT) on Prevention of HIV Infections in Pregnant Women, Mothers and their Infants. Geneva, 2006 [cited 2007 May 24]. Available from: http://www.who.int/child-adolescent-health/publications/NUTRITION/consensus_statement.htm.
77. Kline M.W. Perspectives on the pediatric HIV/AIDS pandemic: catalyzing access of children to care and treatment. Pediatrics 117 (2006) 1388-1393
78. Nelson L.J., and Wells C.D. Global epidemiology of childhood tuberculosis. Int J Tuberc Lung Dis 8 (2004) 636-647
79. Stop TB Partnership Childhood TB Subgroup World Health Organization. Guidance for National Tuberculosis Programmes on the management of tuberculosis in children. Chapter 1: introduction and diagnosis of tuberculosis in children. Int J Tuberc Lung Dis 10 (2006) 1091-1097
80. Nelson L.J., and Wells C.D. Tuberculosis in children: considerations for children from developing countries. Semin Pediatr Infect Dis 15 (2004) 150-154
81. Enarson P.M., Enarson D.A., and Gie R. Management of tuberculosis in children in low-income countries. Int J Tuberc Lung Dis 9 (2005) 1299-1304
82. Grange J.M., and Zumla A. Tuberculosis. In: Cook G.C., and Zumla A. (Eds). Manson's Tropical Diseases. 21st Edition (2003), Elsevier Science, London 995-1052
83. Adams L.V. Childhood tuberculosis in the developing world. Pediatr Ann 33 (2004) 685-690
84. Colditz G.A., Berkey C.S., Mosteller F., Brewer T.F., Wilson M.E., Burdick E., et al. The efficacy of bacillus Calmette-Guerin vaccination of newborns and infants in the prevention of tuberculosis: meta-analyses of the published literature. Pediatrics 96 1 Pt. 1 (1995) 29-35
85. Trunz B.B., Fine P., and Dye C. Effect of BCG vaccination on childhood tuberculous meningitis and miliary tuberculosis worldwide: a meta-analysis and assessment of cost-effectiveness. Lancet 367 (2006) 1173-1180
86. WHO. TB/HIV. A Clinical Manual. 2nd Edition (2004), WHO, Geneva. http://www.who.int/tb/publications/who_htm_tb_2004_329/en/index.html [cited 2007 May 2]. Available from: http://www.who.int/tb/publications/who_htm_tb_2004_329/en/index.html.
87. Neumann C.G., Gewa C., and Bwibo N.O. Child nutrition in developing countries. Pediatr Ann 33 (2004) 658-674
88. Muller O., and Krawinkel M. Malnutrition and health in developing countries. CMAJ 173 (2005) 279-286
89. Collins S., Dent N., Binns P., Bahwere P., Sadler K., and Hallam A. Management of severe acute malnutrition in children. Lancet 368 (2006) 1992-2000
90. Caulfield L.E., Richard S.A., Rivera J.A., Musgrove P., and Black R.E. Stunting, wasting, and micronutrient deficiency disorders. In: Jamison D.T., Breman J.G., Measham A.R., Alleyne G., Claeson M., Evans D.B., et al. (Eds). Disease control priorities in developing countries. 2nd Edition (2006), Oxford University Press, New York 551-567. http://www.dcp2.org/pubs/DCP [cited 2007 May 10]. Available from: http://www.dcp2.org/pubs/DCP.
91. Bhan M.K., Bhandari N., and Bahl R. Management of the severely malnourished child: perspective from developing countries. BMJ 326 (2003) 146-151
92. UNICEF. The 2006 State of the World's Children. Excluded and Invisible (2006), UNICEF, New York. http://www.unicef.org/sowc06/ [cited 2007 March 28]. Available from: http://www.unicef.org/sowc06/.
93. Rice A.L., Sacco L., Hyder A., and Black R.E. Malnutrition as an underlying cause of childhood deaths associated with infectious diseases in developing countries. Bull World Health Organ 78 (2000) 1207-1221
94. Bahl R., Frost C., Kirkwood B.R., Edmond K., Martines J., Bhandari N., et al. Infant feeding patterns and risks of death and hospitalization in the first half of infancy: multicentre cohort study. Bull World Health Organ 83 (2005) 418-426
95. WHO. Complementary feeding: Report of the global consultation convened jointly by the Department of Child and Adolescent Health and Development and the Department of Nutrition for Health and Development, Geneva, 10-13 December 2001 and Summary of guiding principles for complementary feeding of the breastfed child (2002), WHO, Geneva. http://www.who.int/child-adolescent-health/publications/NUTRITION/Report_CF.htm [cited 2007 June 20]. Available from: http://www.who.int/child-adolescent-health/publications/NUTRITION/Report_CF.htm.
96. Nestel P., Briend A., de Benoist B., Decker E., Ferguson E., Fontaine O., et al. Complementary food supplements to achieve micronutrient adequacy for infants and young children. J Pediatr Gastroenterol Nutr 36 (2003) 316-328
97. Bhutta Z.A. Effect of infections and environmental factors on growth and nutritional status in developing countries. J Pediatr Gastroenterol Nutr 43 Suppl 3 (2006) S13-S21
98. UNICEF. Progress for children: a report card on nutrition. Number 4, May, 2006 (2006), UNICEF, New York. http://www.unicef.org/progressforchildren/2006n4/index.html [cited 2007 June 15]. Available from: http://www.unicef.org/progressforchildren/2006n4/index.html.
99. West Jr. K.P. Vitamin A deficiency disorders in children and women. Food Nutr Bull 24 Suppl 4 (2003) S78-S90
100. Ramakrishnan U., Aburto N., McCabe G., and Martorell R. Multimicronutrient interventions but not vitamin a or iron interventions alone improve child growth: results of 3 meta-analyses. J Nutr 134 (2004) 2592-2602
101. Beaton GH, Martorell R, Aronson KA, Edmonston B, McCabe G, Ross AC, et al. Vitamin A supplementation and child morbidity and mortality in developing countries. Food Nutr Bull 1993/1994;15 [cited 2007 June 15]. Available from: http://www.unu.edu/unupress/food/8F154e/8F154E00.htm.
102. Fawzi W.W., Chalmers T.C., Herrera M.G., and Mosteller F. Vitamin A supplementation and child mortality. A meta-analysis. JAMA 269 (1993) 898-903
103. UNICEF. UNICEF Statistics: Vitamin A Deficiency [updated 2006 May; cited 2007 June 20]. Available from: http://childinfo.org/areas/vitamina/.
104. Huiming Y., Chaomin W., and Meng M. Vitamin A for treating measles in children. Cochrane Database Syst Rev 4 (2005) CD001479.
105. Brown N., and Roberts C. Vitamin A for acute respiratory infection in developing countries: a meta-analysis. Acta Paediatr 93 (2004) 1437-1442
106. Ross D.A. Recommendations for vitamin A supplementation. J Nutr 132 Suppl 9 (2002) S2902-S2906
107. Maberly G.F., Haxton D.P., and van der Haar F. Iodine deficiency: consequences and progress toward elimination. Food Nutr Bull 24 Suppl 4 (2003) S91-S98
108. WHO. Iodine Status Worldwide. WHO Global Database on Iodine Deficiency (2004), World Health Organization, Geneva. http://whqlibdoc.who.int/publications/2004/9241592001.pdf [cited 2007 May 26]. Available from: http://whqlibdoc.who.int/publications/2004/9241592001.pdf.
109. Bhatnagar S., and Natchu U.C. Zinc in child health and disease. Indian J Pediatr 71 (2004) 991-995
110. Shrimpton R., Gross R., Darnton-Hill I., and Young M. Zinc deficiency: what are the most appropriate interventions?. BMJ 330 (2005) 347-349
111. Black M.M. Micronutrient deficiencies and cognitive functioning. J Nutr 133 11 Suppl 2 (2003) S3927-S3931
112. Bhutta Z.A., Black R.E., Brown K.H., Gardner J.M., Gore S., Hidayat A., et al. Prevention of diarrhea and pneumonia by zinc supplementation in children in developing countries: pooled analysis of randomized controlled trials. Zinc Investigators' Collaborative Group. J Pediatr 135 (1999) 689-697
113. Black R.E. Zinc deficiency, infectious disease and mortality in the developing world. J Nutr 133 5 Suppl 1 (2003) S1485-S1489
114. Bhutta Z.A., Bird S.M., Black R.E., Brown K.H., Gardner J.M., Hidayat A., et al. Therapeutic effects of oral zinc in acute and persistent diarrhea in children in developing countries: pooled analysis of randomized controlled trials. Am J Clin Nutr 72 (2000) 1516-1522
115. Brooks W.A., Yunus M., Santosham M., Wahed M.A., Nahar K., Yeasmin S., et al. Zinc for severe pneumonia in very young children: double-blind placebo-controlled trial. Lancet 363 (2004) 1683-1688
116. Thacher T.D., Fischer P.R., Strand M.A., and Pettifor J.M. Nutritional rickets around the world: causes and future directions. Ann Trop Paediatr 26 (2006) 1-16
117. Stoltzfus R.J. Iron deficiency: global prevalence and consequences. Food Nutr Bull 24 Suppl 4 (2003) S99-S103
118. Ronsmans C., and Graham W.J. Maternal mortality: who, when, where, and why. Lancet 368 (2006) 1189-1200
119. Mannar M.G. Successful food-based programmes, supplementation and fortification. J Pediatr Gastroenterol Nutr 43 Suppl 3 (2006) S47-S53
120. Zlotkin S.H., Schauer C., Christofides A., Sharieff W., Tondeur M.C., and Hyder S.M. Micronutrient sprinkles to control childhood anaemia. PLoS Med 2 (2005) e1
121. Smuts C.M., Lombard C.J., Benade A.J., Dhansay M.A., Berger J., Hop le T., et al. Efficacy of a foodlet-based multiple micronutrient supplement for preventing growth faltering, anemia, and micronutrient deficiency of infants: the four country IRIS trial pooled data analysis. J Nutr 135 (2005) S631-S638
122. Hotez P.J., Molyneux D.H., Fenwick A., Ottesen E., Ehrlich Sachs S., and Sachs J.D. Incorporating a rapid-impact package for neglected tropical diseases with programs for HIV/AIDS, tuberculosis, and malaria. PLoS Med 3 (2006) e102
123. Bethony J., Brooker S., Albonico M., Geiger S.M., Loukas A., Diemert D., et al. Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm. Lancet 367 (2006) 1521-1532
124. Hotez P.J., Bundy D.A.P., Beegle K., Brooker L.D., de Silva N., Montresor A., et al. Helminth infections: soil-transmitted helminth infections and schistosomiasis. In: Jamison D.T., Breman J.G., Measham A.R., Alleyne G., Claeson M., Evans D.B., et al. (Eds). Disease control priorities in developing countries. 2nd edition (2006), Oxford University Press, New York 467-482. http://www.dcp2.org/pubs/DCP [cited 2007 May 26]. Available from: http://www.dcp2.org/pubs/DCP.
125. Gilles H.M. Soil-transmitted Helminths (Geohelminths). In: Cook G.C., and Zumla A. (Eds). Manson's tropical diseases. 21st edition (2003), Elsevier Science, London 1527-1560
126. Gryseels B., Polman K., Clerinx J., and Kestens L. Schistosomiasis. Lancet 368 (2006) 1106-1118
127. WHO. Prevention and Control of Schistosomiasis and Soil Transmitted Helminths (2002), WHO, Geneva. http://www.who.int/wormcontrol/documents/joint_statements/en/ppc_unicef_finalreport.pdf [cited 2007 April 27]. Available from: http://www.who.int/wormcontrol/documents/joint_statements/en/ppc_unicef_finalreport.pdf.
128. World Health Organization (WHO). Schistosomiasis and soil-transmitted helminth infections - preliminary estimates of the number of children treated with albendazole or mebendazole. Wkly Epidemiolog Rec 15 (2006) 145-164
129. WHO. Scaling up schistosomiasis and soil-transmitted helminthiasis control. Report from meeting of Members of the Partners for Parasite Control, 14-15 December (2006), WHO, Geneva. http://www.who.int/neglected_diseases/scalingup/en/index.html [cited 2007 June 20]. Available from: http://www.who.int/neglected_diseases/scalingup/en/index.html.
130. Grantham-McGregor S., Cheung Y.B., Cueto S., Glewwe P., Richter L., and Strupp B. Developmental potential in the first 5 years for children in developing countries. Lancet 369 (2007) 60-70
131. Walker S.P., Wachs T.D., Gardner J.M., Lozoff B., Wasserman G.A., Pollitt E., et al. Child development: risk factors for adverse outcomes in developing countries. Lancet 369 (2007) 145-157
132. Engle P.L., Black M.M., Behrman J.R., Cabral de Mello M., Gertler P.J., Kapiriri L., et al. Strategies to avoid the loss of developmental potential in more than 200 million children in the developing world. Lancet 369 (2007) 229-242
133. Olness K. Effects on brain development leading to cognitive impairment: a worldwide epidemic. J Dev Behav Pediatr 24 (2003) 120-130
134. Galler J.R., Ramsey F.C., Forde V., Salt P., and Archer E. Long-term effects of early kwashiorkor compared with marasmus. II. Intellectual performance. J Pediatr Gastroenterol Nutr 6 (1987) 847-854
135. Grantham-McGregor S.M., Powell C.A., Walker S.P., and Himes J.H. Nutritional supplementation, psychosocial stimulation, and mental development of stunted children: the Jamaican Study. Lancet 338 (1991) 1-5
136. Grantham-McGregor S., and Ani C. A review of studies on the effect of iron deficiency on cognitive development in children. J Nutr 131 (2001) S649-S666
137. Lozoff B., Jimenez E., and Smith J.B. Double burden of iron deficiency in infancy and low socioeconomic status: a longitudinal analysis of cognitive test scores to age 19 years. Arch Pediatr Adolesc Med 160 (2006) 1108-1113
138. Iannotti L.L., Tielsch J.M., Black M.M., and Black R.E. Iron supplementation in early childhood: health benefits and risks. Am J Clin Nutr 84 (2006) 1261-1276
139. Boivin M.J., Bangirana P., Byarugaba J., Opoka R.O., Idro R., Jurek A.M., et al. Cognitive impairment after cerebral malaria in children: a prospective study. Pediatrics 119 (2007) e360-e366
140. Olusanya B.O., and Newton V.E. Global burden of childhood hearing impairment and disease control priorities for developing countries. Lancet 369 (2007) 1314-1317
141. Lawn J.E., Cousens S., and Zupan J. 4 million neonatal deaths: when? Where? Why?. Lancet 365 (2005) 891-900
142. Lawn J.E.Z.J., Begkoyian G., and Knippenberg R. Newborn survival. In: Dean J.T.B.J.G., Measham A.R., Alleyne G., Claeson M., Evans D.B., et al. (Eds). Disease control priorities in developing countries. 2nd Edition (2006), Oxford University Press, New York 531-549. http://www.dcp2.org/pubs/DCP [cited 2007 May 26]. Available from: http://www.dcp2.org/pubs/DCP.
143. Knippenberg R., Lawn J.E., Darmstadt G.L., Begkoyian G., Fogstad H., Walelign N., et al. Systematic scaling up of neonatal care in countries. Lancet 365 (2005) 1087-1098
144. Martines J., Paul V.K., Bhutta Z.A., Koblinsky M., Soucat A., Walker N., et al. Neonatal survival: a call for action. Lancet 365 (2005) 1189-1197
145. Khan K.S., Wojdyla D., Say L., Gulmezoglu A.M., and Van Look P.F. WHO analysis of causes of maternal death: a systematic review. Lancet 367 (2006) 1066-1074
146. Stanton C., Lawn J.E., Rahman H., Wilczynska-Ketende K., and Hill K. Stillbirth rates: delivering estimates in 190 countries. Lancet 367 (2006) 1487-1494
147. Jones G., Steketee R.W., Black R.E., Bhutta Z.A., and Morris S.S. How many child deaths can we prevent this year?. Lancet 362 (2003) 65-71
148. WHO Collaborative Study Team on the Role of Breastfeeding on the Prevention of Infant Mortality. Effect of breastfeeding on infant and child mortality due to infectious diseases in less developed countries: a pooled analysis. Lancet 355 (2000) 451-455
149. Caulfield L.E., Huffman S.L., and Piwoz E.G. Interventions to improve intake of complementary foods by infants 6 to 12 months of age in developing countries: impact on growth and on the prevalence of malnutrition and potential contribution to child survival. Food Nutr Bull 20 (1999) 183-200
150. Fewtrell L., Kaufmann R.B., Kay D., Enanoria W., Haller L., and Colford Jr. J.M. Water, sanitation, and hygiene interventions to reduce diarrhoea in less developed countries: a systematic review and meta-analysis. Lancet Infect Dis 5 (2005) 42-52
151. Esrey S.A., Potash J.B., Roberts L., and Shiff C. Effects of improved water supply and sanitation on ascariasis, diarrhoea, dracunculiasis, hookworm infection, schistosomiasis, and trachoma. Bull World Health Organ 69 (1991) 609-621
152. Luby S.P., Agboatwalla M., Feikin D.R., Painter J., Billhimer W., Altaf A., et al. Effect of handwashing on child health: a randomised controlled trial. Lancet 366 (2005) 225-233
153. Victora C.G., Adam T., Bryce J., and Evans D.B. Integrated management of the sick child. In: Jamison D.T., Breman J.G., Measham A.R., Alleyne G., Claeson M., Evans D.B., et al. (Eds). Disease control priorities in developing countries. 2nd Edition (2006), Oxford University Press, New York 1177-1191. http://www.dcp2.org/pubs/DCP [cited 2007 May 26]. Available from: http://www.dcp2.org/pubs/DCP.
154. WHO. Handbook: IMCI integrated management of childhood illness (2005), WHO, Geneva. http://www.who.int/child-adolescent-health/New_Publications/IMCI/WHO_FCH_CAH_00.12/IMCI_Handbook.pdf [cited 2007 May 19]. Available from: http://www.who.int/child-adolescent-health/New_Publications/IMCI/WHO_FCH_CAH_00.12/IMCI_Handbook.pdf.
155. Armstrong Schellenberg J., Bryce J., de Savigny D., Lambrechts T., Mbuya C., Mgalula L., et al. The effect of Integrated Management of Childhood Illness on observed quality of care of under-fives in rural Tanzania. Health Policy Plan 19 (2004) 1-10
156. Armstrong Schellenberg J.R., Adam T., Mshinda H., Masanja H., Kabadi G., Mukasa O., et al. Effectiveness and cost of facility-based Integrated Management of Childhood Illness (IMCI) in Tanzania. Lancet 364 (2004) 1583-1594
157. Huicho L., Davila M., Gonzales F., Drasbek C., Bryce J., and Victora C.G. Implementation of the Integrated Management of Childhood Illness strategy in Peru and its association with health indicators: an ecological analysis. Health Policy Plan 20 Suppl 1 (2005) i32-i41
158. El Arifeen S., Blum L.S., Hoque D.M., Chowdury E.K., Khan R., Black R.E., et al. Integrated Management of Childhood Illness (IMCI) in Bangladesh: early findings from a cluster-randomised study. Lancet 364 (2004) 1595-1602
159. Bryce J., Victora C.G., Habicht J.P., Vaughan J.P., and Black R.E. The multi-country evaluation of the integrated management of childhood illness strategy: lessons for the evaluation of public health interventions. Am J Public Health 94 (2004) 406-415
160. Bryce J., Terreri N., Victora C.G., Mason E., Daelmans B., Bhutta Z.A., et al. Countdown to 2015: tracking intervention coverage for child survival. Lancet 368 (2006) 1067-1076
161. Claeson M., Gillespie D., Mshinda H., Troedsson H., and Victora C.G. Knowledge into action for child survival. Lancet 362 (2003) 323-327
162. Victora C.G., Fenn B., Bryce J., and Kirkwood B.R. Co-coverage of preventive interventions and implications for child-survival strategies: evidence from national surveys. Lancet 366 (2005) 1460-1466
163. Fotso J.C. Child health inequities in developing countries: differences across urban and rural areas. Int J Equity Health 5 (2006) 9
164. Schellenberg J.A., Victora C.G., Mushi A., de Savigny D., Schellenberg D., Mshinda H., et al. Inequities among the very poor: health care for children in rural southern Tanzania. Lancet 361 (2003) 561-566
165. Wirth M.E., Balk D., Delamonica E., Storeygard A., Sacks E., and Minujin A. Setting the stage for equity-sensitive monitoring of the maternal and child health millennium development goals. Bull World Health Organ 84 (2006) 519-527
166. Victora C.G., Huicho L., Amaral J.J., Armstrong-Schellenberg J., Manzi F., Mason E., et al. Are health interventions implemented where they are most needed?. District uptake of the integrated management of childhood illness strategy in Brazil, Peru and the United Republic of Tanzania. Bull World Health Organ 84 (2006) 792-801