Emerging role of dendritic cells in respiratory viral infection

Journal of Molecular Medicine

Volumn 85, Issue 10, 2007, Pages 1057-1068

  Grayson, Mitchell H ^a   Holtzman, Michael J ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Dendritic cell; Immune response; Viral respiratory diseases

Indexed keywords

INTERFERON;

ANTIGEN PRESENTATION; CELL FUNCTION; CELL MATURATION; CELL TYPE; DENDRITIC CELL; HOMEOSTASIS; HUMAN; IMMUNE RESPONSE; INFLUENZA; LUNG; NONHUMAN; PHENOTYPE; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; REVIEW; T LYMPHOCYTE; VIRAL RESPIRATORY TRACT INFECTION;

ANTIGEN PRESENTATION; ANTIGEN-PRESENTING CELLS; CELL PROLIFERATION; DENDRITIC CELLS; HUMANS; IMMUNE TOLERANCE; IMMUNITY, ACTIVE; IMMUNITY, NATURAL; INTERFERON-ALPHA; LUNG; LYMPHOCYTE ACTIVATION; METAPNEUMOVIRUS; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUS, HUMAN;

EID: 34748875393     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-007-0212-3     Document Type: Review

References (84)

1. Ampofo K, Gesteland PH, Bender J et al (2006) Epidemiology, complications, and cost of hospitalization in children with laboratory-confirmed influenza infection. Pediatrics 118:2409-2417
2. Hall CB (2001) Respiratory syncytial virus and parainfluenza virus. N Engl J Med 344:1917-1928
3. Henrickson KJ, Kuhn SM, Savatski LL (1994) Epidemiology and cost of infection with human parainfluenza virus types 1 and 2 in young children. Clin Infect Dis 18:770-779
4. Shortman K, Liu YJ (2002) Mouse and human dendritic cell subtypes. Nat Rev Immunol 2:151-161
5. Chan CW, Crafton E, Fan HN et al (2006) Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity. Nat Med 12:207-213
6. Kelsall BL, Biron CA, Sharma O, Kaye PM (2002) Dendritic cells at the host-pathogen interface. Nat Immunol 3:699-702
7. Holt PG, Haining S, Nelson DJ, Sedgwick JD (1994) Origin and steady-state turnover of class II MHC-bearing dendritic cells in the epithelium of the conducting airways. J Immunol 153:256-261
8. Stumbles PA, Strickland DH, Pimm CL et al (2001) Regulation of dendritic cell recruitment into resting and inflamed airway epithelium: use of alternative chemokine receptors as a function of inducing stimulus. J Immunol 167:228-234
9. Luster AD (2002) The role of chemokines in linking innate and adaptive immunity. Curr Opin Immunol 14:129-135
10. Cochand L, Isler P, Songeon F, Nicod LP (1999) Human lung dendritic cells have an immature phenotype with efficient mannose receptors. Am J Respir Cell Mol Biol 21:547-554
11. Grayson MH (2006) Lung dendritic cells and the inflammatory response. Ann Allergy Asthma Immun 96:643-651
12. Eisenbarth SC, Piggott DA, Huleatt JW, Visintin I, Herrick CA, Bottomly K (2002) Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen. J Exp Med 196:1645-1651
13. Saeki H, Moore AM, Brown MJ, Hwang ST (1999) Cutting edge: secondary lymphoid-tissue chemokine (SLC) and CC chemokine receptor 7 (CCR7) participate in the emigration pathway of mature dendritic cells from the skin to regional lymph nodes. J Immunol 162:2472-2475
14. Hurez V, Saparov A, Tousson A et al (2003) Restricted clonal expression of IL-2 by naive T cells reflects differential dynamic interactions with dendritic cells. J Exp Med 198:123-132
15. Barchet W, Blasius A, Cella M, Colonna M (2005) Plasmacytoid dendritic cells: in search of their niche in immune responses. Immunol Res 32:75-84
16. Colonna M, Trinchieri G, Liu YJ (2004) Plasmacytoid dendritic cells in immunity. Nat Immunol 5:1219-1226
17. Diacovo TG, Blasius AL, Mak TW, Cella M, Colonna M (2005) Adhesive mechanisms governing interferon-producing cell recruitment into lymph nodes. J Exp Med 202:687-696
18. Lambrecht BN (2005) Dendritic cells and the regulation of the allergic immune response. Allergy 60:271-282
19. Munn DH, Sharma MD, Hou D et al (2004) Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes. J Clin Invest 114:280-290
20. Dikopoulos N, Bertoletti A, Kroger A, Hauser H, Schirmbeck R, Reimann J (2005) Type I IFN negatively regulates CD8+ T cell responses through IL-10-producing CD4+ T regulatory 1 cells. J Immunol 174:99-109
21. Taieb J, Chaput N, Menard C et al (2006) A novel dendritic cell subset involved in tumor immunosurveillance. Nat Med 12:214-219
22. Ghaznawie M, Papadimitriou JM, Heenan PJ (1999) The steady-state turnover of murine epidermal Langerhans cells. Br J Dermatol 141:57-61
23. Merad M, Manz MG, Karsunky H et al (2002) Langerhans cells renew in the skin throughout life under steady-state conditions. Nat Immunol 3:1135-1141
24. Grayson MH, Holtzman MJ (2006) Chemokine complexity: the case for CCL5. Am J Respir Cell Mol Biol 35:143-146
25. Grayson MH, Rohlfing MM, Holtzman MJ (2006) Lung dendritic cells require CCL5-CCR5 interaction to migrate to lymph nodes during paramyxoviral infection. Proc Am Thorac Soc 3:A827
26. Grayson MH, Holtzman MJ (2006) Chemokine signaling regulates apoptosis as well as immune cell traffic in host defense. Cell Cycle 5:380-383
27. Jahnsen FL, Strickland DH, Thomas JA et al (2006) Accelerated antigen sampling and transport by airway mucosal dendritic cells following inhalation of a bacterial stimulus. J Immunol 177:5861-5867
28. Hammad H, Chieppa M, Huang AY, Lambrecht BN, Germain RN (2006) Intravital visualization of MHCII-EGFP+ airway dendritic cells using two-photon microscopy. Proc Am Thorac Soc 3:A828
29. Asselin-Paturel C, Brizard G, Pin JJ, Briere F, Trinchieri G (2003) Mouse strain differences in plasmacytoid dendritic cell frequency and function revealed by a novel monoclonal antibody. J Immunol 171:6466-6477
30. Wang H, Peters N, Schwarze J (2006) Plasmacytoid dendritic cells limit viral replication, pulmonary inflammation, and airway hyperresponsiveness in respiratory syncytial virus infection. J Immunol 177:6263-6270
31. Stoll S, Delon J, Brotz TM, Germain RN (2002) Dynamic imaging of T cell-dendritic cell interactions in lymph nodes. Science 296:1873-1876
32. Dustin ML, Shaw AS (1999) Costimulation: building an immunological synapse. Science 283:649-650
33. Shaw AS, Dustin ML (1997) Making the T cell receptor go the distance: a topological view of T cell activation. Immunity 6:361-369
34. Salio M, Cella M, Suter M, Lanzavecchia A (1999) Inhibition of dendritic cell maturation by herpes simplex virus. Eur J Immunol 29:3245-3253
35. Engelmayer J, Larsson M, Subklewe M et al (1999) Vaccinia virus inhibits the maturation of human dendritic cells: a novel mechanism of immune evasion. J Immunol 163:6762-6768
36. Fugier-Vivier I, Servet-Delprat C, Rivailler P, Rissoan MC, Liu YJ, Rabourdin-Combe C (1997) Measles virus suppresses cell-mediated immunity by interfering with the survival and functions of dendritic and T cells. J Exp Med 186:813-823
37. Tortorella D, Gewurz BE, Furman MH, Schust DJ, Ploegh HL (2000) Viral subversion of the immune system. Annu Rev Immunol 18:861-926
38. Mizushima N, Yamamoto A, Matsui M, Yoshimori T, Ohsumi Y (2004) In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell 15:1101-1111
39. Paludan C, Schmid D, Landthaler M et al (2005) Endogenous MHC class II processing of a viral nuclear antigen after autophagy. Science 307:593-596
40. Swanson MS (2006) Autophagy: eating for good health. J Immunol 177:4945-4951
41. Belz GT, Behrens GM, Smith CM et al (2002) The CD8alpha(+) dendritic cell is responsible for inducing peripheral self-tolerance to tissue-associated antigens. J Exp Med 196:1099-1104
42. Basta S, Bennink JR (2003) A survival game of hide and seek: cytomegaloviruses and MHC class I antigen presentation pathways. Viral Immunol 16:231-242
43. Fonteneau JF, Kavanagh DG, Lirvall M et al (2003) Characterization of the MHC class I cross-presentation pathway for cell-associated antigens by human dendritic cells. Blood 102:4448-4455
44. Melief CJ (2003) Mini-review: regulation of cytotoxic T lymphocyte responses by dendritic cells: peaceful coexistence of cross-priming and direct priming? Eur J Immunol 33:2645-2654
45. Ohashi PS, DeFranco AL (2002) Making and breaking tolerance. Curr Opin Immunol 14:744-759
46. Cambi A, de Lange F, van Maarseveen NM et al (2004) Microdomains of the C-type lectin DC-SIGN are portals for virus entry into dendritic cells. J Cell Biol 164:145-155
47. Zhou T, Chen Y, Hao L, Zhang Y (2006) DC-SIGN and immunoregulation. Cell Mol Immunol 3:279-283
48. Gijzen K, Tacken PJ, Zimmerman A et al (2007) Relevance of DC-SIGN in DC-induced T cell proliferation. J Leukoc Biol 81:729-740
49. Wang JP, Liu P, Latz E, Golenbock DT, Finberg RW, Libraty DH (2006) Flavivirus activation of plasmacytoid dendritic cells delineates key elements of TLR7 signaling beyond endosomal recognition. J Immunol 177:7114-7121
50. Lee HK, Lund JM, Ramanathan B, Mizushima N, Iwasaki A (2007) Autophagy-dependent viral recognition by plasmacytoid dendritic cells. Science 315:1398-1401
51. Lopez CB, Moltedo B, Alexopoulou L, Bonifaz L, Flavell RA, Moran TM (2004) TLR-independent induction of dendritic cell maturation and adaptive immunity by negative-strand RNA viruses. J Immunol 173:6882-6889
52. Barchet W, Krug A, Cella M et al (2005) Dendritic cells respond to influenza virus through TLR7- and PKR-independent pathways. Eur J Immunol 35:236-242
53. Kato H, Sato S, Yoneyama M et al (2005) Cell type-specific involvement of RIG-I in antiviral response. Immunity 23:19-28
54. Lopez CB, Yount JS, Moran TM (2006) Toll-like receptor-independent triggering of dendritic cell maturation by viruses. J Virol 80:3128-3134
55. Theofilopoulos AN, Baccala R, Beutler B, Kono DH (2005) Type I interferons (alpha/beta) in immunity and autoimmunity. Annu Rev Immunol 23:307-336
56. Prechtel AT, Turza NM, Kobelt DJ et al (2005) Infection of mature dendritic cells with herpes simplex virus type 1 dramatically reduces lymphoid chemokine-mediated migration. J Gen Virol 86:1645-1657
57. Galocha B, Hill A, Barnett BC et al (1997) The active site of ICP47, a herpes simplex virus-encoded inhibitor of the major histocompatibility complex (MHC)-encoded peptide transporter associated with antigen processing (TAP), maps to the NH2-terminal 35 residues. J Exp Med 185:1565-1572
58. Raftery MJ, Winau F, Kaufmann SH, Schaible UE, Schonrich G (2006) CD1 antigen presentation by human dendritic cells as a target for herpes simplex virus immune evasion. J Immunol 177:6207-6214
59. Chaudhry A, Das SR, Hussain A et al (2005) The Nef protein of HIV-1 induces loss of cell surface costimulatory molecules CD80 and CD86 in APCs. J Immunol 175:4566-4574
60. Holtzman MJ, Battaile JT, Patel AC (2006) Immunogenetic programs for viral induction of mucous cell metaplasia. Am J Respir Cell Mol Biol 35:29-39
61. Sigurs N (2002) A cohort of children hospitalised with acute RSV bronchiolitis: impact on later respiratory disease. Paediatr Respir Rev 3:177-183
62. Guerrero-Plata A, Casola A, Suarez G et al (2006) Differential response of dendritic cells to human metapneumovirus and respiratory syncytial virus. Am J Respir Cell Mol Biol 34:320-329
63. Wang H, Peters N, Laza-Stanca V, Nawroly N, Johnston SL, Schwarze J (2006) Local CD11c+ MHC class II-precursors generate lung dendritic cells during respiratory viral infection, but are depleted in the process. J Immunol 177:2536-2542
64. Smit JJ, Rudd BD, Lukacs NW (2006) Plasmacytoid dendritic cells inhibit pulmonary immunopathology and promote clearance of respiratory syncytial virus. J Exp Med 203:1153-1159
65. Lo MS, Brazas RM, Holtzman MJ (2005) Respiratory syncytial virus nonstructural proteins NS1 and NS2 mediate inhibition of Stat2 expression and type I interferon responsiveness. J Virol 79:9315-9319
66. Lopez CB, Yount JS, Hermesh T, Moran TM (2006) Sendai virus infection induces efficient adaptive immunity independently of type I interferons. J Virol 80:4538-4545
67. Fernandez-Sesma A, Marukian S, Ebersole BJ et al (2006) Influenza virus evades innate and adaptive immunity via the NS1 protein. J Virol 80:6295-6304
68. Osterlund P, Veckman V, Siren J et al (2005) Gene expression and antiviral activity of alpha/beta interferons and interleukin-29 in virus-infected human myeloid dendritic cells. J Virol 79:9608-9617
69. Geiss GK, Salvatore M, Tumpey TM et al (2002) Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza. Proc Natl Acad Sci U S A 99:10736-10741
70. Legge KL, Braciale TJ (2003) Accelerated migration of respiratory dendritic cells to the regional lymph nodes is limited to the early phase of pulmonary infection. Immunity 18:265-277
71. Piqueras B, Connolly J, Freitas H, Palucka AK, Banchereau J (2006) Upon viral exposure, myeloid and plasmacytoid dendritic cells produce 3 waves of distinct chemokines to recruit immune effectors. Blood 107:2613-2618
72. Mukaida N (2003) Pathophysiological roles of interleukin-8/CXCL8 in pulmonary diseases. Am J Physiol 284:L566-L577
73. Zammit DJ, Cauley LS, Pham QM, Lefrancois L (2005) Dendritic cells maximize the memory CD8 T cell response to infection. Immunity 22:561-570
74. Schlecht G, Garcia S, Escriou N, Freitas AA, Leclerc C, Dadaglio G (2004) Murine plasmacytoid dendritic cells induce effector/memory CD8+ T-cell responses in vivo after viral stimulation. Blood 104:1808-1815
75. Fonteneau JF, Gilliet M, Larsson M et al (2003) Activation of influenza virus-specific CD4+ and CD8+ T cells: a new role for plasmacytoid dendritic cells in adaptive immunity. Blood 101:3520-3526
76. Chaperot L, Blum A, Manches O et al (2006) Virus or TLR agonists induce TRAIL-mediated cytotoxic activity of plasmacytoid dendritic cells. J Immunol 176:248-255
77. Spierings DC, de Vries EG, Vellenga E et al (2004) Tissue distribution of the death ligand TRAIL and its receptors. J Histochem Cytochem 52:821-831
78. Berent-Maoz B, Piliponsky AM, Daigle I, Simon HU, Levi-Schaffer F (2006) Human mast cells undergo TRAIL-induced apoptosis. J Immunol 176:2272-2278
79. Mazzoni A, Leifer CA, Mullen GE, Kennedy MN, Klinman DM, Segal DM (2003) Cutting edge: histamine inhibits IFN-alpha release from plasmacytoid dendritic cells. J Immunol 170:2269-2273
80. Banchereau J, Pascual V (2006) Type I interferon in systemic lupus erythematosus and other autoimmune diseases. Immunity 25:383-392
81. Gilliet M, Conrad C, Geiges M et al (2004) Psoriasis triggered by toll-like receptor 7 agonist imiquimod in the presence of dermal plasmacytoid dendritic cell precursors. Arch Dermatol 140:1490-1495
82. Nestle FO, Conrad C, Tun-Kyi A et al (2005) Plasmacytoid predendritic cells initiate psoriasis through interferon-alpha production. J Exp Med 202:135-143
83. Meylan E, Tschopp J, Karin M (2006) Intracellular pattern recognition receptors in the host response. Nature 442:39-44
84. Kawai T, Akira S (2006) TLR signaling. Cell Death Differ 13:816-825