The active site of ICP47, a herpes simplex virus-encoded inhibitor of the major histocompatibility complex (MHC)-encoded peptide transporter associated with antigen processing (TAP), maps to the NH2-terminal 35 residues

Journal of Experimental Medicine

Volumn 185, Issue 9, 1997, Pages 1565-1572

  Galocha, Begoña ^a   Hill, Ann ^a,d   Barnett, Barbara C ^b   Dolan, Aidan ^b   Raimondi, Alejandra ^a,e   Cook, Richard F ^a   Brunner, Joseph ^c   McGeoch, Duncan J ^b   Ploegh, Hidde L ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b INSTITUTE OF VIROLOGY   (United Kingdom)

^c ETH ZURICH   (Switzerland)

^d OHSU   (United States)

^e Building 300 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANTIGEN PRESENTATION; ARTICLE; CROSS LINKING; CYTOTOXIC T LYMPHOCYTE; ENDOPLASMIC RETICULUM; ENZYME ACTIVE SITE; GENE TRANSLOCATION; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; IMMEDIATE EARLY GENE; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR RECOGNITION; MULTIDRUG RESISTANCE; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; VIRUS INFECTION;

AMINO ACID SEQUENCE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BASE SEQUENCE; BINDING SITES; BIOLOGICAL TRANSPORT; HUMANS; IMMEDIATE-EARLY PROTEINS; MACROMOLECULAR SUBSTANCES; MAJOR HISTOCOMPATIBILITY COMPLEX; MICE; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; SIMPLEXVIRUS; STRUCTURE-ACTIVITY RELATIONSHIP; VIRAL PROTEINS;

EID: 0030922680     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.185.9.1565     Document Type: Article

References (24)

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