메뉴 건너뛰기




Volumn 12, Issue 7, 2007, Pages 2761-2771

Role of TWEAK and Fn14 in tumor biology

Author keywords

Angiogenesis; Cancer; Fn14; Inflammation; Neoplasia; TNF; Tumor; Tumor necrosis factor; TWEAK

Indexed keywords

TNFSF12 PROTEIN, HUMAN; TNFSF12 PROTEIN, MOUSE; TUMOR MARKER; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR; TWEAK RECEPTOR;

EID: 34648869728     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/2270     Document Type: Review
Times cited : (44)

References (87)
  • 2
    • 0038320242 scopus 로고    scopus 로고
    • TWEAK, a member of the TNF superfamily, is a multifunctional cytokine that binds the TweakR/Fn14 receptor
    • DOI 10.1016/S1359-6101(03)00019-4
    • Wiley, S. R. and J. A. Winkles: TWEAK, a member of the TNF superfamily, is a multifunctional cytokine that binds the TweakR/Fn14 receptor. Cytokine Growth Factor Rev 14, 241-249 (2003) (Pubitemid 36693144)
    • (2003) Cytokine and Growth Factor Reviews , vol.14 , Issue.3-4 , pp. 241-249
    • Wiley, S.R.1    Winkles, J.A.2
  • 3
    • 24644506070 scopus 로고    scopus 로고
    • The role of TWEAK/Fn14 in the pathogenesis of inflammation and systemic autoimmunity
    • Campbell, S., J. Michaelson, L. Burkly and C. Putterman: The role of TWEAK/Fn14 in the pathogenesis of inflammation and systemic autoimmunity. Front Biosci 9, 2273-2284 (2004)
    • (2004) Front Biosci , vol.9 , pp. 2273-2284
    • Campbell, S.1    Michaelson, J.2    Burkly, L.3    Putterman, C.4
  • 6
    • 0033843466 scopus 로고    scopus 로고
    • The Fn14 immediate-early response gene is induced during liver regeneration and highly expressed in both human and murine hepatocellular carcinomas
    • Feng, S. Y., Y. Guo, V. M. Factor, S. S. Thorgeirsson, D. W. Bell, J. R. Testa, K. A. Peifley and J. A. Winkles: The Fn14 immediate-early response gene is induced during liver regeneration and highly expressed in both human and murine hepatocellular carcinomas. Am J Pathol 156, 1253-1261 (2000) (Pubitemid 30660004)
    • (2000) American Journal of Pathology , vol.156 , Issue.4 , pp. 1253-1261
    • Feng, S.-L.Y.1    Guo, Y.2    Factor, V.M.3    Thorgeirsson, S.S.4    Bell, D.W.5    Testa, J.R.6    Peifley, K.A.7    Winkles, J.A.8
  • 8
    • 33746093941 scopus 로고    scopus 로고
    • TWEAK binding to the Fn14 cysteine-rich domain depends on charged residues located in both the A1 and D2 modules
    • DOI 10.1042/BJ20051362
    • Brown, S. A. N., H. N. Hanscom, H. Vu, S. A. Brew and J. A. Winkles: TWEAK binding to the Fn14 cysteine-rich domain depends on charged residues located in both the A1 and D2 modules. Biochem J 397, 297-304 (2006) (Pubitemid 44076899)
    • (2006) Biochemical Journal , vol.397 , Issue.2 , pp. 297-304
    • Brown, S.A.N.1    Hanscom, H.N.2    Vu, H.3    Brew, S.A.4    Winkles, J.A.5
  • 9
    • 0038708366 scopus 로고    scopus 로고
    • The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor- associated factors 1, 2, 3 and 5 and mediates nuclear factor-κB activation
    • DOI 10.1042/BJ20021730
    • Brown, S. A. N., C. M. Richards, H. N. Hanscom, S. L. Feng and J. A. Winkles: The Fn14 cytoplasmic tail binds tumour necrosis factor receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-κB activation. Biochem J 371, 395-403 (2003) (Pubitemid 36547622)
    • (2003) Biochemical Journal , vol.371 , Issue.2 , pp. 395-403
    • Brown, S.A.N.1    Richards, C.M.2    Hanscom, H.N.3    Feng, S.-L.Y.4    Winkles, J.A.5
  • 10
    • 13544268326 scopus 로고    scopus 로고
    • L/BCL-W expression
    • DOI 10.1074/jbc.M409906200
    • Tran, N. L., W. S. McDonough, B. A. Savitch, T. F. Sawyer, J. A. Winkles and M. E. Berens: The tumor necrosis factor-like weak inducer of apoptosis (TWEAK)-fibroblast growth factor-inducible 14 (Fn14) signaling system regulates glioma cell survival via NF-κB pathway activation and BCL-XL/BCL-W expression. J Biol Chem 280, 3483-3492 (2005) (Pubitemid 40223813)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.5 , pp. 3483-3492
    • Tran, N.L.1    McDonough, W.S.2    Savitch, B.A.3    Sawyer, T.F.4    Winkles, J.A.5    Berens, M.E.6
  • 11
    • 33645851656 scopus 로고    scopus 로고
    • TWEAK and Fn14: New molecular targets for cancer therapy?
    • Winkles, J. A., N. L. Tran and M. E. Berens: TWEAK and Fn14: New molecular targets for cancer therapy? Cancer Lett 235, 11-17 (2005)
    • (2005) Cancer Lett , vol.235 , pp. 11-17
    • Winkles, J.A.1    Tran, N.L.2    Berens, M.E.3
  • 14
    • 0038320263 scopus 로고    scopus 로고
    • The signaling adaptors and pathways activated by TNF superfamily
    • DOI 10.1016/S1359-6101(03)00021-2
    • Dempsey, P. W., S. E. Doyle, J. Q. He and G. Cheng: The signaling adaptors and pathways activated by TNF superfamily. Cytokine Growth Factor Rev 14, 193-209 (2003) (Pubitemid 36693141)
    • (2003) Cytokine and Growth Factor Reviews , vol.14 , Issue.3-4 , pp. 193-209
    • Dempsey, P.W.1    Doyle, S.E.2    He, J.Q.3    Cheng, G.4
  • 15
    • 0038242506 scopus 로고    scopus 로고
    • TNF-related weak inducer of apoptosis receptor, a TNF receptor superfamily member, activates NF-κB through TNF receptor-associated factors
    • DOI 10.1016/S0006-291X(03)00852-0
    • Han, S., K. Yoon, K. Lee, K. Kim, H. Jang, N. K. Lee, K. Hwang and L. S. Young: TNF-related weak inducer of apoptosis receptor, a TNF receptor superfamily member, activates NF-κB through TNF receptor-associated factors. Biochem Biophys Res Commun 305, 789-796 (2003) (Pubitemid 36597832)
    • (2003) Biochemical and Biophysical Research Communications , vol.305 , Issue.4 , pp. 789-796
    • Han, S.1    Yoon, K.2    Lee, K.3    Kim, K.4    Jang, H.5    Lee, N.K.6    Hwang, K.7    Lee, S.Y.8
  • 21
    • 33744542153 scopus 로고    scopus 로고
    • Tumor necrosis factor-like weak inducer of apoptosis inhibits skeletal myogenesis through sustained activation of nuclear factor-κB and degradation of MyoD protein
    • DOI 10.1074/jbc.M511131200
    • Dogra, C., H. Changotra, S. Mohan and A. Kumar. Tumor necrosis factor-like weak inducer of apoptosis inhibits skeletal myogenesis through sustained activation of nuclear factor-κB and degradation of myoD protein. J Biol Chem 281, 10327-10336 (2006) (Pubitemid 43864571)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.15 , pp. 10327-10336
    • Dogra, C.1    Changotra, H.2    Mohan, S.3    Kumar, A.4
  • 31
    • 0036953306 scopus 로고    scopus 로고
    • Death of HT29 adenocarcinoma cells induced by TNF family receptor activation is caspase-independent and displays features of both apoptosis and necrosis
    • DOI 10.1038/sj.cdd.4401107
    • Wilson, C. A. and J. L. Browning: Death of HT29 adenocarcinoma cells induced by TNF family receptor activation is caspase-independent and displays features of both apoptosis and necrosis. Cell Death Differ 9, 1321-1333 (2002) (Pubitemid 36097702)
    • (2002) Cell Death and Differentiation , vol.9 , Issue.12 , pp. 1321-1333
    • Wilson, C.A.1    Browning, J.L.2
  • 34
    • 0041355229 scopus 로고    scopus 로고
    • TWEAK mediates signal transduction and differentiation of RAW264.7 cells in the absence of Fn14/TweakR. Evidence for a second TWEAK receptor
    • DOI 10.1074/jbc.M302518200
    • Polek, T. C., M. Talpaz, B. G. Darnay and T. Spivak-Kroizman: TWEAK mediates signal transduction and differentiation of RAW264.7 cells in the absence of Fn14/TweakR: evidence for a second TWEAK receptor. J Biol Chem 278, 32317-32323 (2003) (Pubitemid 37048427)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.34 , pp. 32317-32323
    • Polek, T.C.1    Talpaz, M.2    Darnay, B.G.3    Spivak-Kroizman, T.4
  • 38
    • 0036196767 scopus 로고    scopus 로고
    • Proinflammatory activity of TWEAK on human dermal fibroblasts and synoviocytes: Blocking and enhancing effects of anti-TWEAK monoclonal antibodies
    • DOI 10.1186/ar388
    • Chicheportiche, Y., R. Chicheportiche, I. Sizing, J. Thompson, C. B. Benjamin, C. Ambrose and J. Dayer: Proinflammatory activity of TWEAK on human dermal fibroblasts and synoviocytes: blocking and enhancing effects of anti-TWEAK monoclonal antibodies. Arthritis Res 4, 126-133 (2002) (Pubitemid 34257346)
    • (2002) Arthritis Research , vol.4 , Issue.2 , pp. 126-133
    • Chicheportiche, Y.1    Chicheportiche, R.2    Sizing, I.3    Thompson, J.4    Benjamin, C.B.5    Ambrose, C.6    Dayer, J.-M.7
  • 40
    • 10844249434 scopus 로고    scopus 로고
    • Soluble tumor necrosis factor-like weak inducer of apoptosis overexpression in HEK293 cells promotes tumor growth and angiogenesis in athymic nude mice
    • DOI 10.1158/0008-5472.CAN-04-1879
    • Ho, D. H., H. Vu, S. A. N. Brown, P. J. Donohue, H. N. Hanscom and J. A. Winkles: Soluble tumor necrosis factorlike weak inducer of apoptosis overexpression in HEK293 cells promotes tumor growth and angiogenesis in athymic nude mice. Cancer Res 64, 8968-8972 (2004) (Pubitemid 39665505)
    • (2004) Cancer Research , vol.64 , Issue.24 , pp. 8968-8972
    • Ho, D.H.1    Vu, H.2    Brown, S.A.N.3    Donohue, P.J.4    Hanscom, H.N.5    Winkles, J.A.6
  • 41
    • 27744432820 scopus 로고    scopus 로고
    • Tumor necrosis factor-like weak inducer of apoptosis increases the permeability of the neurovascular unit through nuclear factor-κB pathway activation
    • DOI 10.1523/JNEUROSCI.3382-05.2005
    • Polavarapu, R., M. C. Gongora, J. A. Winkles and M. Yepes: Tumor necrosis factor-like weak inducer of apoptosis increases the permeability of the neurovascular unit through nuclear factor-κB pathway activation. J Neurosci 25, 10094-10100 (2005) (Pubitemid 41636205)
    • (2005) Journal of Neuroscience , vol.25 , Issue.44 , pp. 10094-10100
    • Polavarapu, R.1    Gongora, M.C.2    Winkles, J.A.3    Yepes, M.4
  • 46
    • 3543102542 scopus 로고    scopus 로고
    • Inflammation and necrosis promote tumour growth
    • Vakkila, J. and M. T. Lotze: Inflammation and necrosis promote tumour growth. Nat Rev Immunol 4, 641-648 (2004) (Pubitemid 39025049)
    • (2004) Nature Reviews Immunology , vol.4 , Issue.8 , pp. 641-648
    • Vakkila, J.1    Lotze, M.T.2
  • 47
    • 30144443269 scopus 로고    scopus 로고
    • Paradoxical roles of the immune system during cancer development
    • DOI 10.1038/nrc1782
    • de Visser, K. E., A. Eichten and L. M. Coussens: Paradoxical roles of the immune system during cancer development. Nat Rev Cancer 6, 24-37 (2006) (Pubitemid 43053650)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.1 , pp. 24-37
    • De Visser, K.E.1    Eichten, A.2    Coussens, L.M.3
  • 49
    • 0034613732 scopus 로고    scopus 로고
    • Involvement of TWEAK in interferon gamma-stimulated monocyte cytotoxicity
    • Nakayama, M., N. Kayagaki, N. Yamaguchi, K. Okumura and H. Yagita: Involvement of TWEAK in interferon gamma-stimulated monocyte cytotoxicity. J Exp Med 192, 1373-1380 (2000)
    • (2000) J Exp Med , vol.192 , pp. 1373-1380
    • Nakayama, M.1    Kayagaki, N.2    Yamaguchi, N.3    Okumura, K.4    Yagita, H.5
  • 51
    • 33747173077 scopus 로고    scopus 로고
    • Fn14 is upregulated in cytokine-stimulated vascular smooth muscle cells and is expressed in human carotid atherosclerotic plaques: Modulation by atorvastatin
    • DOI 10.1161/01.STR.0000230648.00027.00, PII 0000767020060800000024
    • Munoz-Garcia, B., J. L. Martin-Ventura, E. Martinez, S. Sanchez, G. Hernandez, L. Ortega, A. Ortiz, J. Egido and L. M. Blanco-Colio: Fn14 is upregulated in cytokinestimulated vascular smooth muscle cells and is expressed in human carotid atherosclerotic plaques: modulation by atorvastatin. Stroke 37, 2044-2053 (2006) (Pubitemid 44309902)
    • (2006) Stroke , vol.37 , Issue.8 , pp. 2044-2053
    • Munoz-Garcia, B.1    Martin-Ventura, J.L.2    Martinez, E.3    Sanchez, S.4    Hernandez, G.5    Ortega, L.6    Ortiz, A.7    Egido, J.8    Blanco-Colio, L.M.9
  • 52
    • 26444605834 scopus 로고    scopus 로고
    • IKK/NF-κB signaling: Balancing life and death - A new approach to cancer therapy
    • DOI 10.1172/JCI26322
    • Luo, J. L., H. Kamata and M. Karin: IKK/NF-κB signaling: balancing life and death-a new approach to cancer therapy. J Clin Invest 115, 2625-2632 (2005) (Pubitemid 41434385)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.10 , pp. 2625-2632
    • Luo, J.-L.1    Kamata, H.2    Karin, M.3
  • 54
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • DOI 10.1038/nature01322
    • Coussens, L. M. and Z. Werb: Inflammation and cancer. Nature 420, 860-867 (2002) (Pubitemid 36019639)
    • (2002) Nature , vol.420 , Issue.6917 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 55
    • 33646160623 scopus 로고    scopus 로고
    • Inflammation, a key event in cancer development
    • Lu, H., W. Ouyang and C. Huang: Inflammation, a key event in cancer development. Mol Cancer Res 4, 221-233 (2006)
    • (2006) Mol Cancer Res , vol.4 , pp. 221-233
    • Lu, H.1    Ouyang, W.2    Huang, C.3
  • 56
    • 0037180812 scopus 로고    scopus 로고
    • Points of control in inflammation
    • DOI 10.1038/nature01320
    • Nathan, C: Points of control in inflammation. Nature 420, 846-852 (2002) (Pubitemid 36019637)
    • (2002) Nature , vol.420 , Issue.6917 , pp. 846-852
    • Nathan, C.1
  • 57
    • 0033020625 scopus 로고    scopus 로고
    • Human endothelium as a source of multifunctional cytokines: Molecular regulation and possible role in human disease
    • DOI 10.1089/107999099314234
    • Krishnaswamy, G., J. Kelley, L. Yerra, J. K. Smith and D. S. Chi: Human endothelium as a source of multifunctional cytokines: molecular regulation and possible role in human disease. J Interferon Cytokine Res 19, 91-104 (1999) (Pubitemid 29109625)
    • (1999) Journal of Interferon and Cytokine Research , vol.19 , Issue.2 , pp. 91-104
    • Krishnaswamy, G.1    Kelley, J.2    Yerra, L.3    Smith, J.K.4    Chi, D.S.5
  • 58
    • 0036094303 scopus 로고    scopus 로고
    • Leukocyte-endothelial cell interactions in the inflammatory response
    • DOI 10.1038/labinvest.3780446
    • Muller, W. A: Leukocyte-endothelial cell interactions in the inflammatory response. Lab Invest 82, 521-533 (2002) (Pubitemid 34522364)
    • (2002) Laboratory Investigation , vol.82 , Issue.5 , pp. 521-533
    • Muller, W.A.1
  • 59
    • 0344256483 scopus 로고    scopus 로고
    • Leukocyte and endothelial cell adhesion molecules as targets for therapeutic interventions in inflammatory disease
    • DOI 10.1016/j.tips.2003.10.004
    • Ulbrich, H., E. E. Eriksson and L. Lindbom: Leukocyte and endothelial cell adhesion molecules as targets for therapeutic interventions in inflammatory disease. Trends Pharmacol Sci 24, 640-647 (2003) (Pubitemid 37494786)
    • (2003) Trends in Pharmacological Sciences , vol.24 , Issue.12 , pp. 640-647
    • Ulbrich, H.1    Eriksson, E.E.2    Lindbom, L.3
  • 60
    • 17644394616 scopus 로고    scopus 로고
    • Smoldering and polarized inflammation in the initiation and promotion of malignant disease
    • DOI 10.1016/j.ccr.2005.02.013
    • Balkwill, F., K. A. Charles and A. Mantovani: Smoldering and polarized inflammation in the initiation and promotion of malignant disease. Cancer Cell 7, 211-217 (2005) (Pubitemid 40568680)
    • (2005) Cancer Cell , vol.7 , Issue.3 , pp. 211-217
    • Balkwill, F.1    Charles, K.A.2    Mantovani, A.3
  • 61
    • 28244456279 scopus 로고    scopus 로고
    • Tumor inflammatory angiogenesis and its chemoprevention
    • DOI 10.1158/0008-5472.CAN-05-3473
    • Albini, A., F. Tosetti, R. Benelli and D. M. Noonan: Tumor inflammatory angiogenesis and its chemoprevention. Cancer Res 65, 10637-10641 (2005) (Pubitemid 41713327)
    • (2005) Cancer Research , vol.65 , Issue.23 , pp. 10637-10641
    • Albini, A.1    Tosetti, F.2    Benelli, R.3    Noonan, D.M.4
  • 62
    • 31544441610 scopus 로고    scopus 로고
    • Distinct role of macrophages in different tumor microenvironments
    • DOI 10.1158/0008-5472.CAN-05-4005
    • Lewis, C. E. and J. W. Pollard: Distinct role of macrophages in different tumor microenvironments. Cancer Res 66, 605-612 (2006) (Pubitemid 43165918)
    • (2006) Cancer Research , vol.66 , Issue.2 , pp. 605-612
    • Lewis, C.E.1    Pollard, J.W.2
  • 63
    • 2342464085 scopus 로고    scopus 로고
    • The two NF-κB activation pathways and their role in innate and adaptive immunity
    • DOI 10.1016/j.it.2004.03.008, PII S1471490604001000
    • Bonizzi, G. and M. Karin: The two NF-κB activation pathways and their role in innate and adaptive immunity. Trends Immunol 25, 280-288 (2004) (Pubitemid 38610351)
    • (2004) Trends in Immunology , vol.25 , Issue.6 , pp. 280-288
    • Bonizzi, G.1    Karin, M.2
  • 64
    • 25844459154 scopus 로고    scopus 로고
    • NF-κB: Linking inflammation and immunity to cancer development and progression
    • DOI 10.1038/nri1703
    • Karin, M. and F. R. Greten: NF-κB: linking inflammation and immunity to cancer development and progression. Nat Rev Immunol 5, 749-759 (2005) (Pubitemid 41400849)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.10 , pp. 749-759
    • Karin, M.1    Greten, F.R.2
  • 65
    • 0037699955 scopus 로고    scopus 로고
    • Angiogenesis in health and disease
    • DOI 10.1038/nm0603-653
    • Carmeliet, P: Angiogenesis in health and disease. Nat Med 9, 653-660 (2003) (Pubitemid 36749213)
    • (2003) Nature Medicine , vol.9 , Issue.6 , pp. 653-660
    • Carmeliet, P.1
  • 66
    • 0037967272 scopus 로고    scopus 로고
    • Tumorigenesis and the angiogenic switch
    • DOI 10.1038/nrc1093
    • Bergers, G. and L. E. Benjamin: Tumorigenesis and the angiogenic switch. Nat Rev Cancer 3, 401-410 (2003) (Pubitemid 37328844)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.6 , pp. 401-410
    • Bergers, G.1    Benjamin, L.E.2
  • 67
    • 0242624629 scopus 로고    scopus 로고
    • Molecular basis of angiogenesis and cancer
    • Tonini, T., F. Rossi and P. P. Claudio: Molecular basis of angiogenesis and cancer. Oncogene 22, 6549-6556 (2003) (Pubitemid 37372334)
    • (2003) Oncogene , vol.22 , Issue.43 , pp. 6549-6556
    • Tonini, T.1    Rossi, F.2    Claudio, P.P.3
  • 68
    • 1242340428 scopus 로고    scopus 로고
    • Antiangiogenic cancer therapy
    • DOI 10.1016/j.semcancer.2003.09.018
    • Cao, Y: Antiangiogenic cancer therapy. Semin Cancer Biol 14, 139-145 (2004) (Pubitemid 38234756)
    • (2004) Seminars in Cancer Biology , vol.14 , Issue.2 , pp. 139-145
    • Cao, Y.1
  • 69
    • 26444578334 scopus 로고    scopus 로고
    • Targeted therapies for esophageal cancer
    • DOI 10.1634/theoncologist.10-8-590
    • Tew, W. P., D. P. Kelsen and D. H. Ilson: Targeted therapies for esophageal cancer. Oncologist 10, 590-601 (2005) (Pubitemid 41429122)
    • (2005) Oncologist , vol.10 , Issue.8 , pp. 590-601
    • Tew, W.P.1    Kelsen, D.P.2    Ilson, D.H.3
  • 70
    • 33745822387 scopus 로고    scopus 로고
    • Esophageal cancer: A review and update
    • Layke, J. C. and P. P. Lopez: Esophageal cancer: a review and update. Am Fam Physician 73, 2187-2194 (2006) (Pubitemid 44031616)
    • (2006) American Family Physician , vol.73 , Issue.12 , pp. 2187-2194
    • Layke, J.C.1    Lopez, P.P.2
  • 73
    • 33745547361 scopus 로고    scopus 로고
    • New therapies for hepatocellular carcinoma
    • DOI 10.1038/sj.onc.1209550, PII 1209550
    • Avila, M. A., C. Berasain, B. Sangro and J. Prieto: New therapies for hepatocellular carcinoma. Oncogene 25, 3866-3884 (2006) (Pubitemid 43980482)
    • (2006) Oncogene , vol.25 , Issue.27 , pp. 3866-3884
    • Avila, M.A.1    Berasain, C.2    Sangro, B.3    Prieto, J.4
  • 74
    • 23144442644 scopus 로고    scopus 로고
    • Breast cancer metastasis: Markers and models
    • DOI 10.1038/nrc1670
    • Weigelt, B., J. L. Peterse and L. J. van't Veer: Breast cancer metastasis: markers and models. Nat Rev Cancer 5, 591-602 (2005) (Pubitemid 41081385)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.8 , pp. 591-602
    • Weigelt, B.1    Peterse, J.L.2    Van't Veer, L.J.3
  • 75
    • 2442495498 scopus 로고    scopus 로고
    • Development of novel targeted therapies in the treatment of malignant glioma
    • Rich, J. N. and D. D. Bigner: Development of novel targeted therapies in the treatment of malignant glioma. Nat Rev Drug Discov 3, 430-446 (2004) (Pubitemid 38618125)
    • (2004) Nature Reviews Drug Discovery , vol.3 , Issue.5 , pp. 430-446
    • Rich, J.N.1    Bigner, D.D.2
  • 76
    • 33645732219 scopus 로고    scopus 로고
    • Molecular pathology of malignant gliomas
    • Louis, D. N: Molecular pathology of malignant gliomas. Ann Rev Pathol Mech Dis 1, 97-117 (2006)
    • (2006) Ann Rev Pathol Mech Dis , vol.1 , pp. 97-117
    • Louis, D.N.1
  • 77
    • 0038179723 scopus 로고    scopus 로고
    • Cost of migration: Invasion of malignant gliomas and implications for treatment
    • DOI 10.1200/JCO.2003.05.063
    • Giese, A., R. Bjerkvig, M. E. Berens and M. Westphal: Cost of migration: invasion of malignant gliomas and implications for treatment. J Clin Oncol 21, 1624-1636 (2003) (Pubitemid 46594118)
    • (2003) Journal of Clinical Oncology , vol.21 , Issue.8 , pp. 1624-1636
    • Giese, A.1    Bjerkvig, R.2    Berens, M.E.3    Westphal, M.4
  • 82
    • 0036235624 scopus 로고    scopus 로고
    • Aberrant nuclear factor-κB activity and its participation in the growth of human malignant astrocytoma
    • Nagai, S., K. Washiyama, M. Kurimoto, A. Takaku, S. Endo and T. Kumanishi: Aberrant nuclear factor-κB activity and its participation in the growth of human malignant astrocytoma. J Neurosurg 96, 909-917 (2002) (Pubitemid 34415406)
    • (2002) Journal of Neurosurgery , vol.96 , Issue.5 , pp. 909-917
    • Nagai, S.1    Washiyama, K.2    Kurimoto, M.3    Takaku, A.4    Endo, S.5    Kumanishi, T.6
  • 83
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia - A key regulatory factor in tumour growth
    • Harris, A. L: Hypoxia-a key regulatory factor in tumour growth. Nat Rev Cancer 2, 38-47 (2002) (Pubitemid 37328806)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.1 , pp. 38-47
    • Harris, A.L.1
  • 84
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza, G. L: Targeting HIF-1 for cancer therapy. Nat Rev Cancer 3, 721-732 (2003) (Pubitemid 37328811)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.10 , pp. 721-732
    • Semenza, G.L.1
  • 86
    • 0142151019 scopus 로고    scopus 로고
    • Fibroblast Growth Factor-Inducible-14 Is Induced in Axotomized Neurons and Promotes Neurite Outgrowth
    • Tanabe, K., I. Bonilla, J. A. Winkles and S. M. Strittmatter: Fibroblast growth factor-inducible-14 is induced in axotomized neurons and promotes neurite outgrowth. J Neurosci 23, 9675-9686 (2003) (Pubitemid 37352067)
    • (2003) Journal of Neuroscience , vol.23 , Issue.29 , pp. 9675-9686
    • Tanabe, K.1    Bonilla, I.2    Winkles, J.A.3    Strittmatter, S.M.4
  • 87
    • 27244442108 scopus 로고    scopus 로고
    • Anti-TWEAK monoclonal antibodies reduce immune cell infiltration in the central nervous system and severity of experimental autoimmune encephalomyelitis
    • DOI 10.1016/j.clim.2005.06.005, PII S1521661605001841
    • Desplat-Jego, S., R. Creidy, S. Varriale, N. Allaire, Y. Luo, D. Bernard, K. Hahm, L. Burkly and J. Boucraut: Anti-TWEAK monoclonal antibodies reduce immune cell infiltration in the central nervous system and severity of experimental autoimmune encephalomyelitis. Clin Immunol 117, 15-23 (2005) (Pubitemid 41725465)
    • (2005) Clinical Immunology , vol.117 , Issue.1 , pp. 15-23
    • Desplat-Jego, S.1    Creidy, R.2    Varriale, S.3    Allaire, N.4    Luo, Y.5    Bernard, D.6    Hahm, K.7    Burkly, L.8    Boucraut, J.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.