TWEAK is expressed by glial cells, induces astrocyte proliferation and increases EAE severity

Journal of Neuroimmunology

Volumn 133, Issue 1-2, 2002, Pages 116-123

  Desplat Jégo, Sophie ^a   Varriale, Simone ^a   Creidy, Rita ^a   Terra, Rafik ^a   Bernard, Dominique ^a   Khrestchatisky, Michel ^a   Izui, Shozo ^b   Chicheportiche, Yves ^c   Boucraut, José ^a  

^a CNRS   (France)

^b UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^c CyGen   (Switzerland)

Author keywords

Cytokines; Experimental auto immune encephalomyelitis; Glial cells; TWEAK

Indexed keywords

FN14 RECEPTOR; MESSENGER RNA; TUMOR NECROSIS FACTOR RECEPTOR; TWEAK RECEPTOR; UNCLASSIFIED DRUG;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL MODEL; ARTICLE; ASTROCYTE; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DISEASE SEVERITY; GLIA CELL; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; SPINAL CORD; TRANSGENIC MOUSE;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; ASTROCYTES; CARRIER PROTEINS; CELL DIVISION; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; DISEASE PROGRESSION; DISEASE SUSCEPTIBILITY; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; GENE EXPRESSION REGULATION; INFLAMMATION MEDIATORS; MICE; MICE, TRANSGENIC; MICROGLIA; RNA, MESSENGER; TUMOR NECROSIS FACTORS;

EID: 0036889706     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(02)00368-5     Document Type: Article

References (46)

1. Aloisi F. Immune function of microglia. Glia. 36:2001;165-179.
2. Armitage R.J. Tumor necrosis factor receptor superfamily members and their ligands. Curr. Opin. Immunol. 6:1994;407-413.
3. Becher B., Durell B.G., Miga A.V., Hickey W.F., Noelle R.J. The clinical course of experimental autoimmune encephalomyelitis and inflammation is controlled by the expression of CD40 within the central nervous system. J. Exp. Med. 193:2001;967-974.
4. Benveniste E.N. Inflammatory cytokines within the central nervous system: sources, function, and mechanism of action. Am. J. Physiol. 263:1992;C1-C16.
5. Bernard C.C., Johns T.G., Slavin A., Ichikawa M., Ewing C., Liu J., Bettadapura J. Myelin oligodendrocyte glycoprotein: a novel candidate autoantigen in multiple sclerosis. J. Mol. Med. 75:1997;77-88.
6. Bodmer J.L., Schneider P., Tschopp J. The molecular architecture of the TNF superfamily. Trends Biochem. Sci. 27:2002;19-26.
7. Chicheportiche Y., Bourdon P.R., Xu H., Hsu Y.M., Scott H., Hession C., Garcia I., Browning J.L. TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis. J. Biol. Chem. 272:1997;32401-32410.
8. Chicheportiche Y., Fossati-Jimack L., Moll S., Ibnou-Zekri N., Izui S. Down-regulated expression of TWEAK mRNA in acute and chronic inflammatory pathologies. Biochem. Biophys. Res. Commun. 279:2000;162-165.
9. Chicheportiche Y., Chicheportiche R., Sizing I., Thompson J., Benjamin C.B., Ambrose C., Dayer J.M. Proinflammatory activity of TWEAK on human dermal fibroblasts and synoviocytes: blocking and enhancing effects of anti-TWEAK monoclonal antibodies. Arthritis Res. 4:2002;126-133.
10. De Groot C.J., Woodroofe M.N. The role of chemokines and chemokine receptors in CNS inflammation. Prog. Brain Res. 132:2001;533-544.
11. Dowling P., Shang G., Raval S., Menonna J., Cook S., Husar W. Involvement of the CD95 (APO-1/Fas) receptor/ligand system in multiple sclerosis brain. J. Exp. Med. 184:1996;1513-1518.
12. Ferrer I., Puig B., Krupinsk J., Carmona M., Blanco R. Fas and Fas ligand expression in Alzheimer's disease. Acta Neuropathol. (Berlin). 102:2001;121-131.
13. Gerritse K., Laman J.D., Noelle R.J., Aruffo A., Ledbetter J.A., Boersma W.J., Claassen E. CD40-CD40 ligand interactions in experimental allergic encephalomyelitis and multiple sclerosis. Proc. Natl. Acad. Sci. U. S. A. 93:1996;2499-2504.
14. Goddard D.R., Bunning R.A., Woodroofe M.N. Astrocyte and endothelial cell expression of ADAM 17 (TACE) in adult human CNS. Glia. 34:2001;267-271.
15. Hilliard B., Wilmen A., Seidel C., Liu T.S., Goke R., Chen Y. Roles of TNF-related apoptosis-inducing ligand in experimental autoimmune encephalomyelitis. J. Immunol. 166:2001;1314-1319.
16. Howard L.M., Miga A.J., Vanderlugt C.L., Dal Canto M.C., Laman J.D., Noelle R.J., Miller S.D. Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosis. J. Clin. Invest. 103:1999;281-290.
17. Jakubowski A., Browning B., Lukashev M., Sizing I., Thompson J.S., Benjamin C.D., Hsu Y.M., Ambrose C., Zheng T.S., Burkly L.C. Dual role for TWEAK in angiogenic regulation. J. Cell Sci. 115:2002;267-274.
18. Kaptein A., Jansen M., Dilaver G., Kitson J., Dash L., Wang E., Owen M.J., Bodmer J.L., Tschopp J., Farrow S.N. Studies on the interaction between TWEAK and the death receptor WSL-1/TRAMP (DR3). FEBS Lett. 485:2000;135-141.
19. Karpus W.J., Ransohoff R.M. Chemokine regulation of experimental autoimmune encephalomyelitis: temporal and spatial expression patterns govern disease pathogenesis. J. Immunol. 161:1998;2667-2671.
20. Kayagaki N., Kawasaki A., Ebata T., Ohmoto H., Ikeda S., Inoue S., Yoshino K., Okumura K., Yagita H. Metalloproteinase-mediated release of human Fas ligand. J. Exp. Med. 182:1995;1777-1783.
21. Kaye J.F., Kerlero de Rosbo N., Mendel I., Flechter S., Hoffman M., Yust I., Ben-Nun A. The central nervous system-specific myelin oligodendrocytic basic protein (MOBP) is encephalitogenic and a potential target antigen in multiple sclerosis (MS). J. Neuroimmunol. 102:2000;189-198.
22. Korner H., Riminton D.S., Strickland D.H., Lemckert F.A., Pollard J.D., Sedgwick J.D. Critical points of tumor necrosis factor action in central nervous system autoimmune inflammation defined by gene targeting. J. Exp. Med. 186:1997;1585-1590.
23. Lynch C.N., Wang Y.C., Lund J.K., Chen Y.W., Leal J.A., Wiley S.R. TWEAK induces angiogenesis and proliferation of endothelial cells. J. Biol. Chem. 274:1999;8455-8459.
24. Ma Z., Qin H., Benveniste E.N. Transcriptional suppression of matrix metalloproteinase-9 gene expression by ifn-gamma and ifn-beta: critical role of stat-1alpha. J. Immunol. 167:2001;5150-5159.
25. Marsters S.A., Sheridan J.P., Pitti R.M., Brush J., Goddard A., Ashkenazi A. Identification of a ligand for the death-domain-containing receptor Apo3. Curr. Biol. 8:1998;525-528.
26. Meighan-Mantha R.L., Hsu D.K., Guo Y., Brown S.A., Feng S.L., Peifley K.A., Alberts G.F., Copeland N.G., Gilbert D.J., Jenkins N.A., Richards C.M., Winkles J.A. The mitogen-inducible Fn14 gene encodes a type I transmembrane protein that modulates fibroblast adhesion and migration. J. Biol. Chem. 274:1999;33166-33176.
27. Menendez Iglesias B., Cerase J., Ceracchini C., Levi G., Aloisi F. Analysis of B7-1 and B7-2 costimulatory ligands in cultured mouse microglia: upregulation by interferon-gamma and lipopolysaccharide and downregulation by interleukin-10, prostaglandin E2 and cyclic AMP-elevating agents. J. Neuroimmunol. 72:1997;83-93.
28. Morel Y., Schiano de Colella J.M., Harrop J., Deen K.C., Holmes S.D., Wattam T.A., Khandekar S.S., Truneh A., Sweet R.W., Gastaut J.A., Olive D., Costello R.T. Reciprocal expression of the TNF family receptor herpes virus entry mediator and its ligand LIGHT on activated T cells: LIGHT down-regulates its own receptor. J. Immunol. 165:2000;4397-4404.
29. Nakayama M., Kayagaki N., Yamaguchi N., Okumura K., Yagita H. Involvement of TWEAK in interferon gamma-stimulated monocyte cytotoxicity. J. Exp. Med. 192:2000;1373-1380.
30. Okuda Y., Bernard C.C., Fujimura H., Yanagihara T., Sakoda S. Fas has a crucial role in the progression of experimental autoimmune encephalomyelitis. Mol. Immunol. 35:1998;317-326.
31. Qin H., Moellinger J.D., Wells A., Windsor L.J., Sun Y., Benveniste E.N. Transcriptional suppression of matrix metalloproteinase-2 gene expression in human astroglioma cells by TNF-alpha and IFN-gamma. J. Immunol. 161:1998;6664-6673.
32. Rivera S., Ogier C., Jourquin J., Timsit S., Szklarczyk A.W., Miller K., Gearing A.J., Kaczmarek L., Khrestchatisky M. Gelatinase B and TIMP-1 are regulated in a cell- and time-dependent manner in association with neuronal death and glial reactivity after global forebrain ischemia. Eur. J. Neurosci. 15:2002;19-32.
33. Rosenberg G.A., Cunningham L.A., Wallace J., Alexander S., Estrada E.Y., Grossetete M., Razhagi A., Miller K., Gearing A. Immunohistochemistry of matrix metalloproteinases in reperfusion injury to rat brain: activation of MMP-9 linked to stromelysin-1 and microglia in cell cultures. Brain Res. 893:2001;104-112.
34. Rottman J.B., Smith T., Tonra J.R., Ganley K., Bloom T., Silva R., Pierce B., Gutierrez-Ramos J.C., Ozkaynak E., Coyle A.J. The costimulatory molecule ICOS plays an important role in the immunopathogenesis of EAE. Nat. Immunol. 2:2001;605-611.
35. Saas P., Boucraut J., Quiquerez A.L., Schnuriger V., Perrin G., Desplat-Jego S., Bernard D., Walker P.R., Dietrich P.Y. CD95 (Fas/Apo-1) as a receptor governing astrocyte apoptotic or inflammatory responses: a key role in brain inflammation? J. Immunol. 162:1999;2326-2333.
36. Saas P., Boucraut J., Walker P.R., Quiquerez A.L., Billot M., Desplat-Jego S., Chicheportiche Y., Dietrich P.Y. TWEAK stimulation of astrocytes and the proinflammatory consequences. Glia. 32:2000;102-107.
37. Schneider P., Schwenzer R., Haas E., Muhlenbeck F., Schubert G., Scheurich P., Tschopp J., Wajant H. TWEAK can induce cell death via endogenous TNF and TNF receptor 1. Eur. J. Immunol. 29:1999;1785-1792.
38. Sedgwick J.D., Riminton D.S., Cyster J.G., Korner H. Tumor necrosis factor: a master-regulator of leukocyte movement. Immunol. Today. 21:2000;110-113.
39. Seilhean D., Kobayashi K., He Y., Uchihara T., Rosenblum O., Katlama C., Bricaire F., Duyckaerts C., Hauw J.J. Tumor necrosis factor-alpha, microglia and astrocytes in AIDS dementia complex. Acta Neuropathol. (Berlin). 93:1997;508-517.
40. Selmaj K.W., Farooq M., Norton W.T., Raine C.S., Brosnan C.F. Proliferation of astrocytes in vitro in response to cytokines. A primary role for tumor necrosis factor. J. Immunol. 144:1990;129-135.
41. Tamada K., Shimozaki K., Chapoval A.I., Zhai Y., Su J., Chen S.F., Hsieh S.L., Nagata S., Ni J., Chen L. LIGHT, a TNF-like molecule, costimulates T cell proliferation and is required for dendritic cell-mediated allogeneic T cell response. J. Immunol. 164:2000;4105-4110.
42. Tanaka M., Itai T., Adachi M., Nagata S. Downregulation of Fas ligand by shedding. Nat. Med. 4:1998;31-36.
43. Tardiff J., Krauter K.S. Divergent expression of alpha1-protease inhibitor genes in mouse and human. Nucleic Acids Res. 26:1998;3794-3799.
44. Waldner H., Sobel R.A., Howard E., Kuchroo V.K. Fas- and FasL-deficient mice are resistant to induction of autoimmune encephalomyelitis. J. Immunol. 159:1997;3100-3103.
45. Wells G.M., Catlin G., Cossins J.A., Mangan M., Ward G.A., Miller K.M., Clements J.M. Quantitation of matrix metalloproteinases in cultured rat astrocytes using the polymerase chain reaction with a multi-competitor cDNA standard. Glia. 18:1996;332-340.
46. Wiley S.R., Cassiano L., Lofton T., Davis-Smith T., Winkles J.A., Lindner V., Liu H., Daniel T.O., Smith C.A., Fanslow W.C. A novel TNF receptor family member binds TWEAK and is implicated in angiogenesis. Immunity. 15:2001;837-846.