TWEAK/Fn14 interaction stimulates human bronchial epithelial cells to produce IL-8 and GM-CSF

Biochemical and Biophysical Research Communications

Volumn 318, Issue 2, 2004, Pages 422-427

  Xu, Hongri ^a   Okamoto, Atsushi ^a   Ichikawa, Jiro ^a   Ando, Takashi ^a   Tasaka, Kachio ^a   Masuyama, Keisuke ^a   Ogawa, Hideoki ^b   Yagita, Hideo ^b   Okumura, Ko ^b   Nakao, Atsuhito ^a,b  

^a UNIVERSITY OF YAMANASHI   (Japan)

^b JUNTENDO UNIVERSITY   (Japan)

Author keywords

Bronchial epithelial cell; Fn14; GM CSF; I B ; IL 8; TWEAK

Indexed keywords

FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR INDUCIBLE 14; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; I KAPPA B ALPHA; INTERLEUKIN 8; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR LIKE WEAK INDUCER OF APOPTOSIS; UNCLASSIFIED DRUG;

ARTICLE; BRONCHUS MUCOSA; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION;

APOPTOSIS REGULATORY PROTEINS; BRONCHI; CARRIER PROTEINS; CELL LINE; CELL MEMBRANE; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; FLOW CYTOMETRY; GENE EXPRESSION; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; I-KAPPA B PROTEINS; INTERLEUKIN-8; MEMBRANE PROTEINS; PHOSPHORYLATION; RECEPTORS, TUMOR NECROSIS FACTOR; RECOMBINANT PROTEINS; TUMOR NECROSIS FACTORS;

EID: 11144353572     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.04.036     Document Type: Article

References (19)

1. Chicheportiche Y., Bourdon P.R., Xu H., Hsu Y.M., Scott H., Hession C., Garciha I., Brownin J.L. TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis. J. Biol. Chem. 272:1997;32401-32410
2. Wiley S.R., Winkles J.A. TWEAK, a member of the TNF superfamily, is a multifunctional cytokine that binds the TweakR/Fn14 receptor. Cytokine Growth Factor Rev. 14:2003;241-249
3. Schneider P., Schwngzere R., Haas E., Muhlenbeck F., Schubert G., Scheurich P., Tschopp J., Wajant H. TWEAK can induce cell death via endogenous TNF and TNF receptor 1. Eur. J. Immunol. 29(8):1999;1785-1792
4. Nakayama M., Kayagaki Y., Yamaguchi N., Okumura K., Yagita H H. Involvement of TWEAK in interferon-γ-stimulated monocyte cytotoxicity. J. Exp. Med. 192:2000;1373-1380
5. Lynch C.N., Wang Y.C., Lund J.K., Chen Y.W., Leal J.A., Wiley S.R. TWEAK induces angiogenesis and proliferation of endothelial cells. J. Biol. Chem. 274:1999;8455-8459
6. Harada N., Nakayama M., Nakano H., Fukuchi Y., Yagita H., Okumura K. Pro-inflammatory effect of TWEAK/Fn14 interaction on human umbilical vein endothelial cells. Biochem. Biophys. Res. Commun. 299:2002;488-493
7. Chicheportiche Y., Chicheportiche R., Sizing I., Thompson J., Benjamin C.B., Ambrose C., Dayer J.M. Proinflammatory activity of TWEAK on human dermal fibroblasts and synoviocytes: blocking and enhancing effects of anti-TWEAK monoclonal antibodies. Arthritis Res. 4:2002;126-133
8. Wiley S.R., Cassiano L., Lofton T., Davis-Smith T., Winkeles J.A., Lindner V., Liu H., Daniel T.O., Smith C.A., Fanslow W.C. A novel TNF receptor family member binds TWEAK and is implicated in angiogenesis. Immunity. 15:2001;837-846
9. Meighan-Mantha R.L., Hsu D.K., Guo Y., Brown S.A., Feng S.L., Peifley K.A., Alberts G.F., Copeland N.G., Gilbert D.J., Jenkins N.A., Richards C.M., Winkles J.A. The mitogen-inducible Fn14 gene encodes a type I transmembrane protein that modulates fibroblast adhesion and migration. J. Biol. Chem. 274:1999;33166-33176
10. Saitoh T., Nakayama M., Nakano H., Yagita H., Yamamoto N., Yamaoka S. TWEAK induces NF-κB2 p100 processing and long-lasting NF-κB activation. J. Biol. Chem. 278:2003;36005-36012
11. Nakayama M., Ishidoh K., Kojima Y., Harada N., Kominami E., Okumura K., Yagita H. Fibroblast growth factor-inducible 14 mediates multiple pathways of TWEAK-induced cell death. J. Immunol. 170:2003;341-348
12. Ke Y., Reddel R.R., Gerwin B.I., Miyashita M., McMenamin M., Lechner J.F., Harris C.C. Human bronchial epithelial cells with integrated SV40 virus T antigen genes retain the ability to undergo squamous differentiation. Differentiation. 38:1998;60-66
13. Yamane K., Ihn H., Asano Y., Jinnin M., Tamaki K. Antagonistic effects of TNF-α on TGF-β signaling through down-regulation of TGF-β receptor type II in human dermal fibroblasts. J. Immunol. 171:2003;3855-3862
14. Scaife C.L., Kuang J., Wills J.C., Trowbridge B., Gray P., Manning B.M., Eichwald E.J., Daynes R.A., Kuwada S.K. Nuclear factor κB inhibitors induce adhesion-dependent colon cancer apoptosis: implications for metastasis. Cancer Res. 62:2002;6870-6878
15. Takizawa H. Airway epithelial cells as regulators of airway inflammation. Int. J. Mol. Med. 1:1998;367-378
16. Nakayama M., Ishidoh K., Kayagaki N., Kojima Y., Yamaguchi N., Nakano H., Kominami E., Okumura K., Yagita H. Multiple pathways of TWEAK-induced cell death. J. Immunol. 168:2002;734-743
17. Polek T.C., Talpaz M., Darnay B.G., Spivak-Kroizman T. TWEAK mediates signal transduction and differentiation of RAW264.7 cells in the absence of Fn14/TweakR. J. Biol. Chem. 278:2003;32317-32323
18. Kunsch C., Rosen C.A. NF-κB subunit-specific regulation of the interleukin-8 promoter. Mol. Cell. Biol. 13:1993;6137-6146
19. Schreck R., Baeuerl P.A. NF-κB as inducible transcriptional activator of the GM-CSF gene. Mol. Cell. Biol. 10:1990;1281-1286