Post treatment effect of Grewia asiatica against radiation induced biochemical changes in cerebrum of Swiss albino mice

Pharmacologyonline

Volumn 2, Issue , 2007, Pages 344-354

  Ahaskar, Muktika ^a   Sharma, K V ^a   Singh, Smita ^a   Sisodia, Rashmi ^a  

^a UNIVERSITY OF RAJASTHAN   (India)

Author keywords

Antioxidant; Cerebrum; Grewia asiatica; Lipid peroxidation; Radioprotection; Reduced glutathione

Indexed keywords

ANTHOCYANIN; ANTIOXIDANT; ASCORBIC ACID; CAROTENE; GLUTATHIONE; GREWIA ASIATICA EXTRACT; PLANT EXTRACT; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; AUTOPSY; BRAIN HOMOGENATE; BRAIN PROTECTION; BRAIN RADIATION; COBALT TELETHERAPY; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFICACY; GAMMA RADIATION; GREWIA; GREWIA ASIATICA; LIPID PEROXIDATION; MOUSE; NEUROCHEMISTRY; NONHUMAN; OPTIMAL DRUG DOSE; OXIDATIVE STRESS; PROTEIN DETERMINATION; RADIATION DOSE; RADIATION EXPOSURE; RADIATION PROTECTION; SPECTROPHOTOMETRY;

EID: 34548614194     PISSN: None     EISSN: 18278620     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Adler V, Yin Z, Tew KD, Ronai Z. Role of redox potential and reactive oxygen species in stress signaling. Oncogene. 1999; 18: 104-111.
2. Brock WA, Geara FB. 1995. Clinical Relevance Of Normal Tissue Radiosensitivity, Radiation Research, 10th ed. Wurzburg, ICRR, Society. 1995; 2: 843-846.
3. Agrawal A, Chandra D. Kale RK. Radiation-induced oxidative stress: 2 studies in liver as distant organ of tumor bearing mice. Mol. Biochem.2001; 224: 9-17.
4. Winterbourn CC. Superoxide as an intracellular radical sink. Free Radic. Biol. Med. 1993; 14: 85-90.
5. Floyd RA. Free radical damage to protein and DNA: Mechanisms involved and relevant observations on brain undergoing oxidative stress. Ann. Neurol. 1992; 32: 22-27.
6. Skaper SD, Fabris M, Ferrari V, Dalle Carbonare M, Leon A. Quercetin protects cutaneous tissue-associated cell types including sensory neurons from oxidative stress induced by glutathione depletion: cooperative effects of ascorbic acid. Free Radic. Biol. Med. 1997; 669-678.
7. Robbins MEC, Zhao W. Chronic oxidative stres and radiation-induced late normal tissue injuty: a review. Int. J. Radiat. Oncol. Biol. Phys. 2004; 80: 251-259.
8. Dringen R, Gutterer JM, Hirrlinger J. Glutathione metabolism in brain. Eur. J. Biochem. 200; 267: 4912-4916.
9. Bhattacharya SK, Satyam K, Ghoshal S.Antioxidant activity of glycowithanolides from Withenia somnifera.ind J of expl Biol 1996; 35:236.
10. Yen, Grow-Chin, She, Chig W, Pin-der D. Extraction and identification of components from the levels of Mulberry. J of Agri and Food Chem 1996; 44: 1687-1690.
11. Bhatia AL. The anti-aging role of vitamin A and β-carotene. Indian J Gerontology 1908.
12. Hays WB. Fruit growing in India. 2nd Revised edition. Kitabistan, Allahabad, India. 1953.
13. Sastri BN. The wealth of India: Raw materials #4.Grewia Linn. Tilliaceae. In Council of Scientific and Industrial Research, New Delhi, India. 1956; 260-266.
14. Morton JF. Phalsa, Fruits of warm climate. Julia Morton, Miami, F.L 1987; 276-277.
15. Nair MG, Deueitt DL, Wang H, Krempir DW, Mody DK. Dietary food supplement containing natural cyclooxygenase inhibitors and methods for inhibiting pain and inflammation. United states patent application. 2005.
16. Yadav AK. Phalsa: A Potential New Small Fruit for Georgia. J Janick(ed). 1999; 348-392.
17. Ahaskar M., Sisodia R. Modulation of Radiation induced Biochemical Changes in brain of Swiss Albino Mice by Grewia asiatica. Asian J Exp Sci. 2006; 20(2): 399-404.
18. Moron MS, Depierre JW, Mannervik B. Levels of GSH, GR and GST activities in rat lung and liver. Biochim Biophys Acta 1979; 582: 67-78.
19. Buege JA, Aust SD. In: Methods in Enzymology, Acaddmic Press, New York. 1978; 52: 302-314.
20. Bradford MM. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principal of protein-By binding. Anal.Biochem.1976; 72:248-254.
21. Kale RK, Sitaswad SL. Radiation induced lipid Peroxidation in liposomes. Radiat. Phys. Chem. 1990; 36: 361-364.
22. Biaglow JE, Varnes ME, Epp ER, Clark EP. In: Anticarcinogenesis and Radiation Protection, Eds. P. A. Cerrutti, O. F. Nygaard and M.G. Simic, Plennum Press, New York; 1987:387.
23. Bump EA, Brown JM. Role of glutathione in the radiation response of mammalian cells in vitro and in vivo. Pharmacol Ther. 1990; 47: 117-136.
24. Bacq ZM, Alexander P. Fundamentals of Radiobiology, English Language Book Co. and Pergamon Press. N.Y. 1961.
25. Kim SH, Kim JH, Djorddevic D. Effects of X-irradiation on RNA and protein synthesis in HeLa cells. Radiat. Res. 1970; 42: 577-589.
26. Ahaskar M, Sharma KV, Singh S, Sisodia R. Radioprotective effect of the fruit extract of Grewia asiatica in Swiss albino mice against lethal dose of γ-irradiation. Asian J. Exp. Sci. 2007; 21(2): accepted.
27. Sharma KV, Ahaskar M, Singh S, Sisodia R. Modulation of Radiation Induced Biochemical Alteration in Swiss albino mice by Grewia asiatica (Phalsa). Pharmacologyonline. 2007; 1: 46-54.
28. Singh S, Sharma KV, Sisodia R. Radioprotective Role of Grewia asiatica in Mice Blood. Pharmacologyonline. 2007; 2 accepted.
29. Kaur C, Kapoor HC. Antioxidant activity of some fruits in Indian diet. In ISHS Acta Horticulture; VII International Symposium on Temperate Zone Fruits in the Tropics and Subtropics - Part Two. 2005; 696.
30. Matsumoto H, Nakamura Y, Hirayama M, Yoshiki Y, Okubo K. Antioxidant activity of black currant anthocyanin aglycons and their glycosides measured by chemilurminescence in a neutral pH region and in human plasma. J Agric Food Chem.2002; 50:5034-5037.
31. Wang H, Cao G, Prior RL. Oxygen radical absorbing capacity of anthocyaniins. J Agric Food Chem. 1997; 45:304-309.
32. Gabrielska J, Oszmiański J, Komorowska M, Langner M. Anthocyanin extracts with antioxidant and radical scavenging effect. Z Naturforsch. 1999; 54c: 319-324.
33. Tsuda T, Watanabe M, Ohshima K, Norinobu S, Choi SW, Kawakishi S, Osawa T. Antioxidative activity of the anthocyamin pigments, cyanidin 3-O-ß-D-glucoside and cyanidin. J Agric Food Chem 1994; 42:2407-2410.
34. Wang H, Nair MG, Strasburg GM, Chang YC, Booren AM, Gray JI, DeWitt DL. Antioxidant and antiinflammatory activities of anthocyanins and their aglycon, cyanidin, from tart cherries. J Nat Prod 1999; 62:294-296.
35. Ramirez-Tortosa C, Andersen OM, Gardner PT, Morrice PC, Wood SG, Duthie SJ, Collins AR, Duthie GG. Anthocyanin-rich extract decreases indices of lipid peroxidation and DNA damage in vitamin E-depleted rats. Free Radic Biol Med. 2001; 31:1033-1037.
36. Delgado-Vargas F, Jiménez AR, Paredes-López o. Natural Pigments: Carotenoids, Anthocyanins, and Betalains - Characteristics, Biosynthesis, Processing, and Stability. Food Science and Nutrition. 2000; 40(3):173-289.
37. Youdim KA, Dobbie MS, Kuhnle G, Proteggente AR, Abbott NJ, Rice-Evans C. Interaction between flavonoids and the blood-brain barrier: in vitro studies. J. Neurochem.2003; 85(1): 180-92
38. Joseph JA, Denisova NA, Bielinski D, Fisher DR, Shukitt-Hale B. Oxidative stress protection and vulnerability in aging: Putative nutritional implications for intervention. Mech. Ageing Dev., 2000; 116: 141-153.
39. Amorini AM, Fazzina G, Lazzarino G, Tavazzi B, Di Pierro D, Santucci R, Sinibaldi F, Galvano F, Galvano G. Activity and mechanism of the antioxidant properties of cyanidin-3-O-β-glucopyranoside. Free Rad. Res., 2001; 35: 953-966.
40. Joseph JA, Denisova NA, Arendash G, Gordon M, Diamond D, Shukitt-Hale B, Morgan D. Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model. Nutr. Neurosci., 2003; 6: 153-162.
41. Goyarzu P, Malin DH, Lau FC, Taglialatela G, Moon WD, Jennings R, Moy E, Moy D, Lippold S, Shukitt-Hale B, Joseph JA. Blueberry supplemented diet: Effects on object recognition memory and nuclear factor-kappa B levels in aged rats. Nutr. Neurosci., 2004; 7: 75-83.
42. Sweeney MI, Kalt W, MacKinnon SL, Ashby J, Gottschall-Pass KT. Feeding rats diets enriched in lowbush blueberries for six weeks decreases ischemia-induced brain damage. Nutr. Neurosci., 2002; 5: 427-431.
43. Griffiths HR, Lunec J. Ascorbic acid in the 21st century: more than a simple antioxidant. Environ Toxicol Pharmacol.2001; 10: 173-182.
44. Mc Nulty HP, Byun J, Lockwood SF, Jacob RF, Mason RP. Differential efects of carotenoids on lipid peroxidation due to membrane interactions: X-ray diffraction analysis. Biochim biophys Acta. 2006