DNA methylation markers of surfactant proteins in lung cancer

International Journal of Oncology

Volumn 31, Issue 1, 2007, Pages 181-191

  Lin, Zhenwu ^a   Thomas, Neal J ^a   Bibikova, Marina ^b   Seifart, Carola ^c   Wang, Yunhua ^a   Guo, Xiaoxuan ^a   Wang, Guirong ^a   Vollmer, Ekkehard ^d   Goldmann, Torsten ^d   Garcia, Eliza Wickham ^b   Zhou, Lixin ^b   Fan, Jian Bing ^b   Floros, Joanna ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b ILLUMINA INC   (United States)

^c UNIVERSITY HOSPITAL MARBURG   (Germany)

^d Tuberculosis Center Borstel   (Germany)

Author keywords

DNA methylation; Epigenetics; Lung cancer; Microarray; Surfactant proteins

Indexed keywords

SURFACTANT ASSOCIATED PROTEIN; TUMOR MARKER;

ADENOCARCINOMA; ARTICLE; CPG ISLAND; DNA METHYLATION; DNA SEQUENCE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC MARKER; GENETICS; HUMAN; LUNG TUMOR; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; SQUAMOUS CELL CARCINOMA;

ADENOCARCINOMA; BASE SEQUENCE; CARCINOMA, SQUAMOUS CELL; CPG ISLANDS; DNA METHYLATION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC MARKERS; HUMANS; LUNG NEOPLASMS; MOLECULAR SEQUENCE DATA; PULMONARY SURFACTANT-ASSOCIATED PROTEINS; SEQUENCE ANALYSIS, DNA; TUMOR MARKERS, BIOLOGICAL;

EID: 34548590250     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.31.1.181     Document Type: Article

References (50)

1. Egger G, Liang G, Aparicio A and Jones PA: Epigenetics in human disease and prospects for epigenetic therapy. Nature 429: 457-463, 2004.
2. Laird PW and Jaenisch R: The role of DNA methylation in cancer genetics and epigenetics. Annu Rev Genet 30: 441-464, 1996.
3. Baylin SB and Herman JG: DNA hypermethylation in tumorigenesis: epigenetics joins genetics. Trends Genet 16: 168-174, 2000.
4. Jones PA and Baylin SB: The fundamental role of epigenetic events in cancer. Nat Rev Genet 3: 415-428, 2002.
5. Jones PA and Laird PW: Cancer epigenetics comes of age. Nat Genet 21: 163-167, 1999.
6. Herman JG and Baylin SB: Promoter-region hypermethylation and gene silencing in human cancer. Curr Top Microbiol Immunol 249: 35-54, 2000.
7. Esteller M, Avizienyte E, Corn PG, et al: Epigenetic inactivation of LKB1 in primary tumors associated with the Peutz-Jeghers syndrome. Oncogene 19: 164-168, 2000.
8. Herman JG: Epigenetics in lung cancer: focus on progression and early lesions. Chest 125 (suppl 5): 119S-122S, 2004.
9. Tsou JA, Hagen JA, Carpenter CL and Laird-Offringa IA: DNA methylation analysis: a powerful new tool for lung cancer diagnosis. Oncogene 21: 5450-5461, 2002.
10. Li S, Hursting SD, Davis BJ, McLachlan JA and Barrett JC: Environmental exposure, DNA methylation, and gene regulation: lessons from diethylstilbesterol-induced cancers. Ann NY Acad Sci 983: 161-169, 2003.
11. Moore LE, Huang WY, Chung J and Hayes RB: Epidemiologic considerations to assess altered DNA methylation from environmental exposures in cancer. Ann NY Acad Sci 983: 181-196, 2003.
12. Malkinson AM: Role of inflammation in mouse lung tumorigenesis: a review. Exp Lung Res 31: 57-82, 2005.
13. Brigati C, Noonan DM, Albini A and Benelli R: Tumors and inflammatory infiltrates: friends or foes? Clin Exp Metastasis 19: 247-258, 2002.
14. Marx J: Cancer research. Inflammation and cancer: the link grows stronger. Science 306: 966-968, 2004.
15. Floros J and Phelps DS: Pulmonary surfactant. In: Anesthesia: Biologic Foundations. Yaksh TL, Lynch C III, Zapol WM, Maze M, Biebuck J and Saidman LJ (eds). Lippincott-Raven, pp1259-1279, 1997.
16. Floros J, Wang G and Lin Z: Genetic diversity of human SP-A, a molecule with innate host defense and surfactant-related function; characteristics, primary function, and significance. Curr Pharmacogenomics 3: 87-95, 2005.
17. Lin Z, deMello DE, Wallot M and Floros J: An SP-B gene mutation responsible for SP-B deficiency in fatal congenital alveolar proteinosis: evidence for a mutation hotspot in exon 4. Mol Genet Metab 64: 25-35, 1998.
18. Clark JC, Wert SE, Bachurski CJ, et al: Targeted disruption of the surfactant protein B gene disrupts surfactant homeostasis, causing respiratory failure in newborn mice. Proc Natl Acad Sci USA 92: 7794-7798, 1995.
19. Floros J and Kala P: Surfactant proteins: molecular genetics of neonatal pulmonary diseases. Annu Rev Physiol 60: 365-384, 1998.
20. Floros J and Fan R: Surfactant protein A and B genetic variants and respiratory distress syndrome: allele interactions. Biol Neonate 80 (suppl 1): 22-25, 2001.
21. Floros J and Lin Z: Genetic variability of surfactant protein-B and respiratory distress diseases. Medscape Resp Care 13: 1-6, 1999.
22. Haataja R, Ramet M, Marttila R and Hallman M: Surfactant proteins A and B as interactive genetic determinants of neonatal respiratory distress syndrome. Hum Mol Genet 9: 2751-2760, 2000.
23. deMello DE and Lin Z: Pulmonary alveolar proteinosis: a review. Pediatr Pathol Mol Med 20: 413-432, 2001.
24. Seifart C, Seifart U, Plagens A, Wolf M and von Wichert P: Surfactant protein B gene variations enhance susceptibility to squamous cell carcinoma of the lung in German patients. Br J Cancer 87: 212-217, 2002.
25. Bibikova M, Lin Z, Zhou L, et al: High-throughput DNA methylation profiling using universal bead arrays. Genome Res 16: 383-393, 2006.
26. Fan JB, Oliphant A, Shen R, et al: Highly parallel SNP genotyping. Cold Spring Harb Symp Quant Biol 68: 69-78, 2003.
27. Galinsky VL: Automatic registration of microarray images. II. Hexagonal grid. Bioinformatics 19: 1832-1836, 2003.
28. Lin Z, deMello D, Phelps DS, Koltun WA, Page M and Floros J: Both human SP-A1 and Sp-A2 genes are expressed in small and large intestine. Pediatr Pathol Mol Med 20: 367-386, 2001.
29. Frommer M, McDonald LE, Millar DS, et al: A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands. Proc Natl Acad Sci USA 89: 1827-1831, 1992.
30. Phelps DS: Surfactant regulation of host defense function in the lung: a question of balance. Pediatr Pathol Mol Med 20: 269-292, 2001.
31. Saitoh H, Shimura S, Fushimi T, Okayama H and Shirato K: Detection of surfactant protein-A gene transcript in the cells from pleural effusion for the diagnosis of lung adenocarcinoma. Am J Med 103: 400-404, 1997.
32. Seifart C, Lin HM, Seifart U, et al: Rare SP-A alleles and the SP-A1-6A(4) allele associate with risk for lung carcinoma. Clin Gen 68: 128-136, 2005.
33. Cohen BH, Ball WC Jr, Brashears S, et al: Risk factors in chronic obstructive pulmonary disease (COPD). Am J Epidemiol 105: 223-232, 1977.
34. Mayne ST, Buenconsejo J and Janerich DT: Previous lung disease and risk of lung cancer among men and women nonsmokers. Am J Epidemiol 149: 13-20, 1999. (Pubitemid 29028857)
35. Wu AH, Fontham ET, Reynolds P, et al: Previous lung disease and risk of lung cancer among lifetime nonsmoking women in the United States. Am J Epidemiol 141: 1023-1032, 1995.
36. Coussens LM and Werb Z: Inflammation and cancer. Nature 420: 860-867, 2002.
37. Katsenelson NS, Shurin GV, Bykovskaia SN, Shogan J and Shurin MR: Human small cell lung carcinoma and carcinoid tumor regulate dendritic cell maturation and function. Mod Pathol 14: 40-45, 2001.
38. Brinker KG, Garner H and Wright JR: Surfactant protein A modulates the differentiation of murine bone marrow-derived dendritic cells. Am J Physiol Lung Cell Mol Physiol 284: L232-L241, 2003.
39. Brinker KG, Martin E, Borron P, et al: Surfactant protein D enhances bacterial antigen presentation by bone marrow-derived dendritic cells. Am J Physiol Lung Cell Mol Physiol 281: L1453-L1463, 2001.
40. Yamamoto O, Takahashi H, Hirasawa M, et al: Surfactant protein gene expressions for detection of lung carcinoma cells in peripheral blood. Resp Med 99: 1164-1174, 2005.
41. Uzaslan E, Stuempel T, Ebsen M, et al: Surfactant protein A detection in primary pulmonary adenocarcinoma without bronchioloalveolar pattern. Respiration 72: 249-253, 2005.
42. Jiang F, Caraway NP, Nebiyou Bekele B, et al: Surfactant protein A gene deletion and prognostics for patients with stage I non-small cell lung cancer. Clin Cancer Res 11: 5417-5424, 2005. (Pubitemid 41060816)
43. Hoover RR and Floros J: Organization of the human SP-A and SP-D loci at 10q22-q23. Physical and radiation hybrid mapping reveal gene order and orientation. Am J Respir Cell Mol Biol 18: 353-362, 1998.
44. Wang G, Bates-Kenney SR, Tao JQ, Phelps DS and Floros J: Differences in biochemical properties and in biological function between human SP-A1 and SP-A2 variants, and the impact of ozone-induced oxidation. Biochemistry 43: 4227-4239, 2004.
45. Mikerov AN, Umstead TM, Huang W, Liu W, Phelps DS and Floros J: SP-A1 and SP-A2 variants differentially enhance association of Pseudomonas aeruginosa with rat alveolar macrophages. Am J Physiol Lung Cell Mol Physiol 288: L150-L158, 2005.
46. Wang G, Guo X and Floros J: Differences in the translation efficiency and mRNA stability mediated by 5'-UTR splice variants of human SP-A1 and SP-A2 genes. Am J Physiol Lung Cell Mol Physiol 289: L497-L508, 2005.
47. Cooney CA, Dave AA and Wolff GL: Maternal methyl supplements in mice affect epigenetic variation and DNA methylation of offspring. J Nutr 132 (suppl 8): 2393S-2400S, 2002.
48. Jaenisch R and Bird A: Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet 33 (suppl): 245-254, 2003.
49. Lin Z and Floros J: Heterogeneous allele expression of pulmonary SP-D gene in rat large intestine and other tissues. Physiol Genomics 11: 235-243, 2002.
50. Lin Z, Wang Y, Zhu K and Floros J: Differential allele expression of host defense genes, pulmonary surfactant protein-A and osteopontin, in rat. Mol Immunol 41: 1155-1165, 2004.