Both human SP-A1 and SP-A2 genes are expressed in small and large intestine

Pediatric Pathology and Molecular Medicine

Volumn 20, Issue 5, 2001, Pages 367-386

  Lin, Z ^a   DeMello, D ^a   Phelps, D S ^a   Koltun, W A ^a   Page, M ^a   Floros, J ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

Host defense; Human intestine; SP A; Surfactant

Indexed keywords

MESSENGER RNA; SURFACTANT PROTEIN A;

CONTROLLED STUDY; EPITHELIUM CELL; GENE AMPLIFICATION; GENE EXPRESSION; GENE SEQUENCE; HOST RESISTANCE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTESTINE EPITHELIUM; LARGE INTESTINE; PRIORITY JOURNAL; PSEUDOGENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; SMALL INTESTINE;

BLOTTING, NORTHERN; DNA, COMPLEMENTARY; EPITHELIAL CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; INTESTINE, LARGE; INTESTINE, SMALL; INTESTINES; LUNG; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PROTEOLIPIDS; PSEUDOGENES; PULMONARY SURFACTANT-ASSOCIATED PROTEIN A; PULMONARY SURFACTANT-ASSOCIATED PROTEINS; PULMONARY SURFACTANTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA;

EID: 0034822414     PISSN: 15227952     EISSN: None     Source Type: Journal    
DOI: 10.1080/152279501750399366     Document Type: Review

References (50)

1. Organization of the human SP-A and SP-D loci at 10q22-23. Physical and radiation hybrid mapping reveals gene order and orientation
2. Novel, non-radioactive, simple and multiplex PCR-cRFLP methods for genotyping human SP-A and SP-D marker alleles
3. Genetics of the hydrophilic surfactant proteins A and D
4. 5′ splicing and allelic variants of the human pulmonary surfactant protein A genes
5. Effect of genotype on the levels of surfactant protein-A mRNA and on the SP-A2 splice variants in adult humans
6. SP-A 3′UTR is involved in the glucocorticoid inhibition of human SP-A gene expression
7. Human SP-A protein variants derived from one or both genes stimulate TNF-a production in the THP-1 cell line
8. Surfactant protein A inhibits T cell proliferation via its collagen-like tail and a 210-kDa receptor
9. Pulmonary surfactant
10. Surfactant protein-A activates NF-kappa B in the THP-1 monocytic cell line
11. Surfactant protein A (SP-A) regulates cytokine production in the monocytic cell line THP-1
12. Surfactant protein A-deficient mice are susceptible to group B streptococcal infection
13. Surfactant protein A protects growing cells and reduces TNF-alpha activity from LPS-stimulated macrophages
14. Pulmonary surfactant modulation of host-defense function
15. Pulmonary surfactant protein A (SP-A) is expressed by epithelial cells of small and large intestine
16. Isolation and characterization of surfactant-like particles in rat and human colon
17. Surfactant protein A and D expression in the porcine eustachian tube
18. Antibody against pulmonary surfactant protein A recognizes proteins in intestine and swim bladder of the freshwater fish, carp
19. Structural comparison of recombinant pulmonary surfactant protein A derived from two human coding sequences: Implications for the chain composition of natural human SP-A
20. Regulation of expression of human SP-A1 and SP-A2 genes in fetal lung explant culture
21. Surfactant protein-A secretion and genotype in human airway submucosal glands
22. In situ hybridization of SP-A mRNA in adult human conducting airways
23. The utility of postmortem lung for RNA studies; variability and correlation of the expression of surfactant proteins in human lung
24. An alternative spliced surfactant protein B mRNA in normal human lung: Disease implications
25. Isolation and characterization of the human pulmonary surfactant apoprotein gene
26. Characterization of a second pulmonary surfactant-associated protein SP-A gene
27. Molecular structure of the human cytoplasmic beta-actin gene: Interspecies homology of sequences in the introns
28. Isolation and characterization of cDNA clones for the 35kDa pulmonary surfactant-associated protein
29. An SP-B gene mutation responsible for SP-B deficiency in fatal congenital alveolar proteinosis: Evidence for a mutation hotspot in exon 4
30. Expression of the 35kDa and low molecular surfactant-associated proteins in the lungs of infants dying with respiratory distress syndrome
31. Secretion of surfactant protein A from rat type II pneumocytes
32. Multiplex genotype determination at a large number of gene loci
33. Aberrant SP-B mRNA in lung tissue of patients with congential alveolar proteinosis (CAP)
34. Lamellar bodies in synoviocytes, mesothelium and specific epithelia as possible site of auto-antigen in rheumatoid disease
35. Expression of hydrophilic surfactant proteins by mesentery cells in rat and man
36. Surfactant protein A in rabbit sinus and middle ear mucosa
37. Surfactant protein A promotes attachment of Mycobacterium tuberculosis to alveolar macrophages during infection with human immunodeficiency virus
38. Increased recovery of surfactant protein A in AIDS-related pneumonia
39. Alteration of the endogenous surfactant system in septic adult rats
40. The lung in inflammatory bowel disease
41. Glucocorticoid inhibition of human SP-A1 promoter activity in MCI-H441 cells
42. Differential regulation of SP-A1 and SP-A2 genes by cAMP, glucocorticoids, and insulin
43. Human SP-A1 and SP-A2 genes are differentially regulated during development and by cAMP and glucocorticoids
44. Human surfactant proteins A1 and A2 are differentially regulated during development and by soluble factors
45. Surfactant proteins: Molecular genetics of neonatal pulmonary disease
46. Association of pulmonary surfactant protein A (SP-A) and RDS: Interaction with SP-B
47. Intestinal inflammation: A complex interplay of immune and nonimmune cell interactions
48. On the etiology of Crohn disease
49. The genetics of inflammatory bowel disease
50. Collectins and pulmonary host defense