Surfactant protein B gene variations enhance susceptibility to squamous cell carcinoma of the lung in German patients

British Journal of Cancer

Volumn 87, Issue 2, 2002, Pages 212-217

  Seifart, C ^a   Seifart, U ^a   Plagens, A ^a   Wolf, M ^a   Von Wichert, P ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Lung cancer; Polymorphism; SP B; Squamous cell carcinoma; Surfactant

Indexed keywords

CARCINOGEN; LUNG SURFACTANT; SURFACTANT PROTEIN B;

ADULT; AGED; ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; DNA FLANKING REGION; FEMALE; GENE LOCUS; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GERMANY; HEREDITY; HUMAN; INTRON; LUNG CARCINOMA; LUNG SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA;

EID: 0037100982     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6600353     Document Type: Article

References (37)

1. Lung cancer and cigarette smoking in women: A multicenter case-control study in Europe
2. Influence of surfactant on mucociliary transport
3. Is there a genetic basis for lung cancer susceptibility?
4. Effects of aerolized surfactant in patients with stable chronic bronchitis
5. Occupations and cigarette smoking as factors in lung cancer
6. Interaction of surfactant mixtures with reactive oxygen and nitrogen species
7. Decreased lung compliance and airtrapping in heterozygous SP-B deficient mice
8. Targeted disruption of the surfactant protein B gene disrupts surfactant homeostasis, causing respiratory failure in newborn mice
9. Exogenous surfactant enhances mucociliary clearence in the anaesthetized dog
10. The coding sequence for the human 18,000-dalton hydrophobic pulmonary, surfactant protein is located on chromosome 2 and identifies a restriction fragment polymorphism
11. Low yield of pulmonary surfactant in cigarette smokers
12. Dinucleotide repeats in the human surfactant protein B gene and respiratory distress syndrome
13. Surfactant and inhaled particles in the conducting airways: Structural, stereological, and biophysical aspects
14. Influence on temperature, ciliary beat frequency and mucus fluidity on tracheal mucus velocity in excised horse trachea
15. Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
16. Molecular genetics of lung cancer
17. Effect of artificial surfactant on ciliary beat frequency in guinea pig trachea
18. Surfactant protein B (SP-B) -/- mice are rescued by restoration of SP-B expression in alveolar type II cells but not Clara cells
19. An SP-B gene mutation responsible for SP-B deficiency in fatal congenital alveolar proteinosis: Evidence for a mutation hotspot in exon 4
20. An alternatively-spliced surfactant protein B mRNA in normal human lung: Disease implication
21. In vitro genotoxicity studies of chrysotile asbestos fibers dispersed in stimulated surfactant
22. Biochemical analyses of bronchoalveolar lavage fluids of healthy human volunteer smokers and nonsmokers
23. Morphological features of the interaction between mucus and surfactant on the bronchial mucosa
24. A mutation in the surfactant protein B gene responsible for fetal neonatal respiratory, disease in mutiple kindreds
25. Localization of surfactant protein synthesis in human lung by in situ hybridization
26. Stucture and organization of the gene encoding human pulmonary surfactant proteolipid SP-B
27. Experimental neonatal respiratory failure induced by monoclonal antibody to the hydrophobic surfactant-associated protein SP-B
28. Surfactant diplaces particles torwards the epithelium in airways and alveoli
29. Formation and structure of surface films: Captive bubble surfactometry
30. Surfactant protein B intron 4 variation in German patients with COPD and acute respiratory failure
31. Higher risk of lung cancer in chronic obstructive pulmonary disease: A prospective, matched, controlled study
32. Alveolar macrophage uptake of the environmental particulate titanium dioxide: Role of surfactant components
33. p53 mutations in non-small cell lung cancer in Japan: Association between mutations and smoking
34. Surfactant protein-B defiecient mice are susceptible to hyperoxic lung injury
35. Mapping the human pulmonary surfactant-associated protein B gene (SFTP3) to chromosome 2p12-p11.2
36. Racial differences in allelic distribution at the human pulmonary surfactant protein B gene locus
37. Risk of lung cancer according to histological type and cigarette dosage