Over-expression of amyloid precursor protein in HEK cells alters p53 conformational state and protects against doxorubicin

Journal of Neurochemistry

Volumn 103, Issue 1, 2007, Pages 322-333

  Uberti, Daniela ^a,d   Cenini, Giovanna ^a   Olivari, Luca ^a   Ferrari Toninelli, Giulia ^a   Porrello, Emanuela ^b   Cecchi, Cristina ^c   Pensafini, Anna ^c   Liguri, Gianfranco ^c   Govoni, Stefano ^b   Racchi, Marco ^b   Maurizio, Memo ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

^b UNIVERSITY OF PAVIA   (Italy)

^c UNIVERSITY OF FLORENCE   (Italy)

^d Department of Biomedical Sciences and Biotechnologies ^*  (Italy)

Author keywords

Amyloid precursor protein; Human; p53; Protein tertiary structure

Indexed keywords

ALPHA TOCOPHEROL; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE INHIBITOR; DOXORUBICIN; GAMMA SECRETASE INHIBITOR; PROTEIN P53;

ARTICLE; CELL MEMBRANE; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN FOLDING; SENSITIVITY ANALYSIS; TRANSCRIPTION INITIATION;

AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANTINEOPLASTIC AGENTS; CELL LINE; DOXORUBICIN; HUMANS; KIDNEY; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; PROTEIN FOLDING; TUMOR SUPPRESSOR PROTEIN P53; VITAMIN E;

EID: 34548547171     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2007.04757.x     Document Type: Article

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