Activation-induced cytidine deaminase-mediated sequence diversification is transiently targeted to newly integrated DNA substrates

Journal of Biological Chemistry

Volumn 282, Issue 35, 2007, Pages 25308-25313

  Shu, Yuan Yang ^a   Fugmann, Sebastian D ^a,b   Gramlich, Hillary S ^a   Schatz, David G ^a,c  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c Box 208011 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL CULTURE; ANTIBODIES; DNA; MUTAGENESIS; SUBSTRATES; TRANSCRIPTION;

CYTIDINE DEAMINASE; DIVERSIFICATION; MOLECULAR FEATURES; MUTABILITY;

ENZYMES;

CYTIDINE DEAMINASE; GENOMIC DNA; IMMUNOGLOBULIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE CASSETTE; GENE MUTATION; GENE TARGETING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ANIMALS; B-LYMPHOCYTES; CELL LINE; CHICKENS; CYTIDINE DEAMINASE; HUMANS; IMMUNOGLOBULINS; MUTAGENESIS, INSERTIONAL; MUTATION; SUBSTRATE SPECIFICITY; TIME FACTORS; TRANSCRIPTION, GENETIC;

EID: 34548512009     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M704231200     Document Type: Article

References (34)

1. Reynaud, C. A., Bertocci, B., Dahan, A., and Weill, J. C. (1994) Adv. Immunol. 57, 353-378
2. Parvari, R., Ziv, E., Lantner, F., Heller, D., and Schechter, I. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 3072-3076
3. Arakawa, H., Saribasak, H., and Buerstedde, J. M. (2004) Plos Biol. 2, E179
4. Arakawa, H., Hauschild, J., and Buerstedde, J. M. (2002) Science 295, 1301-1306
5. Harris, R. S., Sale, J. E., Petersen-Mahrt, S. K., and Neuberger, M. S. (2002) Curr. Biol. 12, 435-438
6. Di Noia, J., and Neuberger, M. S. (2002) Nature 419, 43-48
7. Di Noia, J. M., and Neuberger, M. S. (2004) Eur. J. Immunol. 34, 504-508
8. Saribasak, H., Saribasak, N. N., Ipek, F. M., Ellwart, J. W., Arakawa, H., and Buerstedde, J. M. (2006) J. Immunol. 176, 365-371
9. Yelamos, J., Klix, N., Goyenechea, B., Lozano, F., Chui, Y. L., Gonzalez Fernandez, A., Pannell, R., Neuberger, M. S., and Milstein, C. (1995) Nature 376, 225-229
10. Bachl, J., Carlson, C., Gray-Schopfer, V., Dessing, M., and Olsson, C. (2001) J. Immunol. 166, 5051-5057
11. Fukita, Y., Jacobs, H., and Rajewsky, K. (1998) Immunity 9, 105-114
12. Tumas-Brundage, K., and Manser, T. (1997) J. Exp. Med. 185, 239-250
13. Yang, S. Y., Fugmann, S. D., and Schatz, D. G. (2006) J. Exp. Med. 203, 2919-2928
14. Gordon, M. S., Kanegai, C. M., Doerr, J. R., and Wall, R. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 4126-4131
15. Shen, H. M., Peters, A., Baron, B., Zhu, X., and Storb, U. (1998) Science 280, 1750-1752
16. Pasqualucci, L., Migliazza, A., Fracchiolla, N., William, C., Neri, A., Baldini, L., Chaganti, R. S., Klein, U., Kuppers, R., Rajewsky, K., and Dalla-Favera, R. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 11816-11821
17. Pasqualucci, L., Neumeister, P., Goossens, T., Nanjangud, G., Chaganti, R. S., Kuppers, R., and Dalla-Favera, R. (2001) Nature 412, 341-346
18. Muschen, M., Re, D., Jungnickel, B., Diehl, V., Rajewsky, K., and Kuppers, R. (2000) J. Exp. Med. 192, 1833-1840
19. Mizushima, S., and Nagata, S. (1990) Nucleic Acids Res. 18, 5322
20. Arakawa, H., Lodygin, D., and Buerstedde, J. M. (2001) BMC Biotechnol. 1, 7
21. Buerstedde, J. M., Reynaud, C. A., Humphries, E. H., Olson, W., Ewert, D. L., and Weill, J. C. (1990) EMBO J. 9, 921-927
22. Wakabayashi-Ito, N., and Nagata, S. (1994) J. Biol. Chem. 269, 29831-29837
23. Rada, C., and Milstein, C. (2001) EMBO J. 20, 4570-4576
24. Simpson, L. J., and Sale, J. E. (2003) EMBO J. 22, 1654-1664
25. Sale, J. E., Calandrini, D. M., Takata, M., Takeda, S., and Neuberger, M. S. (2001) Nature 412, 921-926
26. Rada, C., Williams, G. T., Nilsen, H., Barnes, D. E., Lindahl, T., and Neuberger, M. S. (2002) Curr. Biol. 12, 1748-1755
27. Kanayama, N., Todo, K., Takahashi, S., Magari, M., and Ohmori, H. (2006) Nucleic Acids Res. 34, e10
28. Martin, A., and Scharff, M. D. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 12304-12308
29. Yoshikawa, K., Okazaki, I. M., Eto, T., Kinoshita, K., Muramatsu, M., Nagaoka, H., and Honjo, T. (2002) Science 296, 2033-2036
30. Ruckerl, F., Mailhammer, R., and Bachl, J. (2004) Mol. Immunol. 41, 1135-1143
31. Wang, C. L., Harper, R. A., and Wabl, M. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 7352-7356
32. Woo, C. J., Martin, A., and Scharff, M. D. (2003) Immunity 19, 479-489
33. Gourzi, P., Leonova, T., and Papavasiliou, F. N. (2006) Immunity 24, 779-786
34. Harris, R. S., and Liddament, M. T. (2004) Nat. Rev. Immunol. 4, 868-877