O2/3 exposure inhibits cell progression affecting cyclin B1/cdk1 activity in SK-N-SH while induces apoptosis in SK-N-DZ neuroblastoma cells

Journal of Cellular Physiology

Volumn 213, Issue 1, 2007, Pages 115-125

  Cannizzaro, A ^a   Verga Falzacappa, C ^a,b   Martinelli, M ^a   Misiti, S ^a,b   Brunetti, E ^a   Bucci, B ^a  

^a FATEBENEFRATELLI HOSPITAL   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CHECKPOINT KINASE 1; CISPLATIN; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; ETOPOSIDE; GEMCITABINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; OXYGEN; OZONE; PROTEIN BAX;

APOPTOSIS; AQUEOUS SOLUTION; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE PROGRESSION; CELL GROWTH; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; EXPOSURE; HUMAN; HUMAN CELL; HYPEROXIA; NEUROBLASTOMA; NEUROBLASTOMA CELL; OXYGEN THERAPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SOLUBILITY;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CDC2 PROTEIN KINASE; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CISPLATIN; CYCLIN B; CYTOPLASM; DEOXYCYTIDINE; ETOPOSIDE; HUMANS; NEUROBLASTOMA; OXYGEN; OZONE; REACTIVE OXYGEN SPECIES;

EID: 34548474524     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21097     Document Type: Article

References (80)

1. Al-Waili NS, Butler GJ, Beale J, Abdullah MS, Hamilton RW, Lee BY, Lucus P, Allen MW, Petrillo RL, Carrey Z, Finkelstein M. 2005. Hyperbaric oxygen in the treatment of patients with cerebral stroke, brain trauma, and neurologic disease. Adv Ther 22:659-678. Review.
2. Bagatell R, Rumcheva P, London WB, Cohn SL, Look T, Brodeur GM, Frantz C, Joshi Vijay, Thorner P, Rao PV, Castleberry R, Bowman LC. 2005. Outcomes of children with intermediate-risk neuroblastoma after treatment stratified by MYCN status and tumor cell ploidy. J Clin Oncol 23:8819-8827.
3. Barzilai A, Yamamoto K. 2004. DNA damage responses to oxidative stress. DNA Repair 3:1109-1115.
4. Bordow SB, Norris MD, Haber PS, Marshall GM, Haber M. 1998. Prognostic significance of MYCN oncogene expression in childhood neuroblastoma. J Clin Oncol 16:3286-3294. Review.
5. Borriello A, Roberto R, Delia RF, Iolascon A. 2002. Proliferate and survive: Cell division cycle and apoptosis in human neuroblastoma. Haematologica 87:196-214.
6. Brodeur GM, Seeger RC, Schwab M, Varmus HE, Bishop JM. 1984. Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science 224:1121-1124.
7. Brodeur GM, Seeger RC, Schwab M, Varmus HE, Bishop JM. 1985. Amplification of N·myc sequences in primary human neuroblastomas: Correlation with advanced disease stage. Prog Clin Biol Res 175:105-113.
8. Cappelletti V, Fioravanti L, Miodini P, Di Fronzo G. 2000. Genistein blocks breast cancer cells in the G(2)M phase of the cell cycle. J Cell Biochem 79:594-600.
9. waf1/cip1 and Wee 1. Biochem Pharmacol 67:717-726.
10. Chien CT, Lee PH, Chen CF, Ma MC, Lai MK, Hsu SM. 2001. De novo demonstration and co-localization of free-radical production and apoptosis formation in rat kidney subjected to ischemia/reperfusion. J Am Soc Nephrol 12:973-982.
11. Clavo B, Perez JL, Lopez L, Suarez G, Lloret M, Rodriguez V, Macias D, Santana M, Hernandez MA, Martin-Oliva R, Robaina F. 2004. Ozone therapy for tumor oxygenation: A pilot study. Evid Based Complement Alternat Med 1:93-98.
12. Clavo B, Ruiz A, Lloret M, Lopez L, Suarez G, Macias D, Rodriguez V, Hernandez MA, Martin-Oliva R, Quintero S, Cuyas JM, Robaina F. 2004. Adjuvant ozonetherapy in advanced head and neck tumors: A comparative study. Evid Based Complement Alternat Med 1:321-325.
13. 1 cyclins in oxidant-induced growth arrest of lung alveolar epithelial cells: Accumulation of inactive cyclin E-DCK2 complexes. J Biol Chem 271:25117-25125.
14. Cui HB, Na XL, Song DF, Liu Y. 2005. Blocking effects of genistein on cell proliferation and possible mechanism in human gastric carcinoma. World J Gastroenterol 11:69-72.
15. D'Agnano I, Antonelli A, Bucci B, Marcucci L, Petrinelli P, Ambra R, Zupi G, Elli R. 1998. Effects of poly(ADP-ribose) polymerase inhibition on cell death and chromosome damage induced by VP16 and bleomycin. Environ Mol Mutagen 32:56-63.
16. Das KC, Dashnamoorthy R. 2004. Hyperoxia activates the ATR-Chk1 pathway and phosphorylates p53 at multiple sites. Am J Physiol Lung Cell Mol Physiol 286:L87-97.
17. Davies KJ. 1999. The broad spectrum of responses to oxidants in proliferating cells: A new paradigm for oxidative stress. IUBMB Life 48:41-47. Review.
18. Desbarats L, Schneider A, Muller D, Burgin A, Eilers M. 1996. Myc: A single gene controls both proliferation and apoptosis in mammalian cells. Experientia 52:1123-1129. Review.
19. Dieperink HI, Blackwell TS, Prince LS. 2006. Hyperoxia and apoptosis in developing mouse lung mesenchyme. Pediatr Res 59:185-190.
20. Ding HF, McGill G, Rowan S, Schmaltz C, Shimamura A, Fisher DE. 1998. Oncogene-dependent regulation of caspase activation by p53 protein in a cell-free system. J Biol Chem 273:28378-28383.
21. Eggert A, Grotzer MA, Zuzak TJ, Wiewrodt BR, Ho R, Ikegaki N, Brodeur GM. 2001. Resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression. Cancer Res 61:1314-1319.
22. El Touny LH, Banerjee PP. 2006. Identification of both Myt-1 and Wee-1 as necessary mediators of the p21 -independent inactivation of the cdc-2/cyclin B1 complex and growth inhibition of TRAMP cancer cells by genistein. Prostate 66:1542-1555.
23. Evan GI, Vousden KH. 2001. Proliferation, cell cycle and apoptosis in cancer. Nature 411:342-348.
24. Fechner G, Dederichs F, Schmidt D, Muller S, Vaupel P, Albers P. 2005. Hyperoxia-induced improvement of the in vitro response to gemcitabine in transitional cell carcinoma. Anticancer Res 25:3413-3418.
25. Freiberg RA, Hammond EM, Jo Dorie M, Welford SM, Giaccia AJ. 2006. DNA damage during reoxigenation elicits a Chk2-dependent checkpoint response. Mol Cell Biol 1598-1609.
26. Fridman JS, Lowe SW. 2003. Control of apoptosis by p53. Oncogene 22:9030-9040. Review.
27. Fulda S, Lutz W, Schwab M, Debatin KM. 1999. MycN sensitizes neuroblastoma cells for drug-induced apoptosis. Oncogene 18:1479-1486.
28. Gautier J, Minshull J, Lohka M, Glotzer M, Hunt T, Mailer JL. 1990. Cyclin is a component of maturation-promoting factor from Xenopus. Cell 60:487-494.
29. Gould KL, Nurse P. 1989. Tyrosine phosphorylation of the fission yeast cdc2 + protein kinase regulates entry into mitosis. Nature 342:39-45.
30. Harris RG, White E, Phillips ES, Lillycrop KA. 2002. The expression of the developmentally regulated proto-oncogene Pax-3 is modulated by N-Myc. J Biol Chem 277:34815-34825.
31. Hirose Y, Berger MS, Pieper RO. 2001. Abrogation of the Chk1-mediated G(2) checkpoint pathway potentiates temozolomide-induced toxicity in a p53-indipendent manner in human glioblastoma cells. Cancer Res 61:5843-5849.
32. Igarashi M, Nagata A, Jinno S, Suto K, Okayama H. 1991. Wcc(+)-like gene in human cells. Nature 353:80-63.
33. 2/M DNA damage checkpoint. J Biol Chem 280:20651-20659.
34. Jin P, Gu Y, Morgan DO. 1996. Role of inhibitory CDC2 phosphorylation in radiation-induced G2 arrest in human cells. J Cell Biol 134:963-970.
35. Jin P, Hardy S, Morgan DO. 1998. Nuclear localization of cyclin B1 controls mitotic entry after DNA damage. J Cell Biol 141:875-885.
36. Katzenstein HM, Cohn SL. 1998. Advances in the diagnosis and treatment of neuroblastoma. Curr Opin Oncol 10:43-51.
37. Krek W, Nigg EA. 1991. Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cell: Evidence for a double block to p34cdc2 kinase activation in vertebrates. EMBOJ 10:3331-3341.
38. Lew DJ, Kornbluth S. 1996. Regulatory roles of cyclin dependent kinase phosphorylation in cell cycle control. Curr Opin Cell Biol 8:795-804.
39. Li C, Wright MM, Jackson RM. 2002. Reactive species mediated injury of human lung epithelial cells after hypoxia-reoxygenation. Exp Lung Res 28:373-389.
40. Li J, Kretzner L 2003. The growth-inhibitory Ndrg1 gene is a Myc negative target in human neuroblastomas and other cell types with overexpressed N- or c-myc. Mol Cell Biochem 250:91-105.
41. Lindskog M, Gleissman H, Ponthan F, Castro J, Kogner P, Johnsen Jl. 2006. Neuroblastoma cell death in response to docosahexaenoic acid: Sensitization to chemotherapy and arsenic-induced oxidative stress. Int J Cancer 118:2584-2593.
42. 2 checkpoint. Oncogene 25:6037-6047.
43. Mantell LL, Lee PJ. 2000. Signal transduction pathway in hyperoxia-induced lung cell death. Mol Genet Metab 71:359-370.
44. Marcu KB, Bossone SA, Patel AJ. 1992. myc function and regulation. Annu Rev Biochem 61:809-860. Review.
45. McGowan CH, Russel P. 1993. Human Wee 1 kinase inhibits cell division by phosphorylating p34cdc2 exclusively on Tyr 15. EMBO J 12:75-85.
46. McGowan CH, Russel P. 1995. Cell cycle regulation of human WEE 1. EMBO J 14:2166-2175.
47. Meitar D, Crawford SE, Rademaker AW, Cohn SL. 1996. Tumor angiogenesis correlates with metastatic disease, N-myc amplification, and poor outcome in human neuroblastoma. J Clin Oncol 14:405-414.
48. Miyashita T, Reed JC. 1995. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80:293-299.
49. Morgan DO. 1997. Cyclin-dependent kinase: Engines, clocks, and microprocessors. Annu Rev Cell Dev Biol 13:261-291.
50. Nelms BE, Maser RS, MacKay JF, Lagally MG, Petrini JH. 1998. In situ visualization of DNA double-strand break repair in human fibroblasts. Science 280:590-592.
51. Norbury C, Blow J, Nurse P. 1991. Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates. EMBO J 10:3321-3329.
52. O'Reilly MA, Staversky RJ, Finkelstein JN, Keng PC. 2003. Activation of the G2 cell cycle checkpoint enhances survival of epithelial cells exposed to hyperoxia. Am J Physiol Lung Cell Mol Physiol 284:L368-L375.
53. Parker LL, Piwnica-Worms H. 1992. Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase. Science 257:1955-1957.
54. Peterson J, Hagan IM. 2005. Polo kinase links the stress pathway to cell cycle control and tip growth in fission yeast. Nature 435:507-512.
55. 2 to M transition. In: Pagano M, editors. Cell Cycle Control, Results Probl Cell Differ. Spring-Verlag. New York: 22:57-78.
56. Porter LA, Donogue DJ. 2003. Cyclin B1 and CD K1: Nuclear localization and upstream regulators. Prog Cell Cycle Res 5:335-347. Review.
57. Poulaki V, Mitsiades N, Romero ME, Tsokos M. 2001. Fas-mediated apoptosis in neuroblastoma requires mitochondrial activation and is inhibited by FLICE inhibitor protein and Bcl-2. Cancer Res 61:4864-4872.
58. Puppo M, Pastorino S, Melillo G, Pezzolo A, Varesio L, Bosco MC. 2004. Induction of apoptosis by flavopiridol in human neuroblastoma cells is enhanced under hypoxia and associated with N-myc proto-oncogene down-regulation. Clin Cancer Res 10:8704-8719.
59. Ray S, Atkuri KR, Deb-Basu D, Adler AS, Chang HY, Herzenberg LA, Felsher DW. 2006. MYC can induce DNA breaks in vivo and in vitro independent of reactive oxygen species. Cancer Res 66:6598-6605.
60. Rueckert RR, Muller GC. 1960. Effect of oxygen tension on HeLa cell growth. Cancer Res 20:944-949.
61. Ribatti D, Raffaghello L, Pastorino F, Nico B, Brignole C, Vacca A, Ponzoni M. 2002. In vivo angiogenic activity of neuroblastoma correlates with MYCN oncogene overexpression. Int J Cancer 102:351-354.
62. Saito A, Maier CM, Narasimhan P, Nishi P, Song YS, Yu F, Liu J, Lee YS, Nito C, Kamada H, Dodd RL, Hsieh LB, Hassid B, Kim EE, Gonzalez M, Chan PH. 2005. Oxidative stress and neuronal death/survival signaling in cerebral ischemia. Mol Neurobiol 31:105-116.
63. Sansone R, Strigtni P, Badiali M, Dominici C, Fontana V, Iolascon A, De Bernardi B, Tonini GP. 1991. Age-dependent prognostic significance of N-myc amplification in neuroblastoma. The Italian experience. Cancer Genet Cytogenet 54:253-257.
64. Shiloh Y, Kastan MB. 2001. ATM: genome stability, neuronal development, and cancer cross paths. Adv Cancer Res 83:209-254. Review.
65. 2/M transition. Biochim Biophys Acta 1519:1-12.
66. Takizawa CG, Morgan DO. 2000. Control of mitosis by changes in the subcellular location of cyclin-B1-Cdk1 and Cdc25C. Curr Opin Cell Biol 12:658-665.
67. Teitz T, Wei T, Valentine MB, Vanin EF, Grenet J, Valentine VA, Behm FG, Look AT, Lahti JM, Kidd VJ. 2000. Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN. Nat Med 6:529-535.
68. Thiele CJ. 1999. Human cell culture. In: Master JRW, Palsson B, editors. London, Great Britain: Kluwer Academic Publishers. P21-22.
69. Tonini GP, Boni L, Pession A, Rogers D, Iolascon A, Basso G, Cordero di Montezemolo L, Casale F, Pession A, Perri P, Mazzocco K, Scaruffi P, Lo Cunsolo C, Marchese N, Milanaccio C, Conte M, Bruzzi P, De Bernardi B. 1997. MYCN oncogene amplification in neuroblastoma is associated with worse prognosis, except in stage 4s: The Italian experience with 295 children. J Clin Oncol 15:85-93.
70. Toyoshima-Morimoto F, Taniguchi E, Shinya N, Iwamatsu A, Nishida E. 2001. Polo-like kinase I phosphorylates cyclin B1 and targets it to the nucleus during prophase. Nature 410:215-220.
71. Triche TJ. 1990. Neuroblastoma and other childhood neural tumors: A review. Pediatric Pathol 10:175-193.
72. van Noesel MM, Pieters R, Voute PA, Versteeg R. 2003. The N-myc paradox: N-myc overexpression in neuroblastomas is associated with sensitivity as well as resistance to apoptosis. Cancer Lett 197:165-172.
73. Vousden KH. 2000. p53: death star. Cell 103:691-694. Review.
74. Wang Q, Hii G, Shusterman S, Mosse Y, Winter CL, Guo C, Zhao H, Rappaport E, Hogarty MD, Maris JM. 2003. ID2 expression is not associated with MYCN amplification or expression in human neuroblastomas. Cancer Res 63:1631-1635.
75. 2 checkpoint and induces apoptosis. Cancer Biol Ther 3:305-313.
76. Ward AJ, Dixon B. 1979. Carcinoma of cervix and HBO. Br J Radiol 52:507-508.
77. Weinstein JL, Katzenstein HM, Cohn SL. 2003. Advances in the diagnosis and treatment of neuroblastoma. Oncologist 8:278-292.
78. Weiss WA, Aldape K, Mohapatra G, Feuerstein BG, Bishop JM. 1997. Targeted expression of MYCN causes neuroblastoma in transgenic mice. EMBO J 16:2985-2995.
79. 2/M regulation. Cell Res 15:143-149.
80. Zweier JL, Duke SS, Kuppusamy P, Sylvester JT, Gabrielson EW. 1989. Electron paramagnetic resonance evidence that cellular oxygen toxicity is caused by the generation of superoxide and hydroxyl free radicals. FEBS Lett 252:12-16.