-
1
-
-
0032969276
-
Islet amyloid: A long-recognized but underappreciated pathological feature of type 2 diabetes
-
Kahn SE, Andrikopoulos S, Verchere CB (1999) Islet amyloid: a long-recognized but underappreciated pathological feature of type 2 diabetes. Diabetes 48:241-253
-
(1999)
Diabetes
, vol.48
, pp. 241-253
-
-
Kahn, S.E.1
Andrikopoulos, S.2
Verchere, C.B.3
-
2
-
-
0031825834
-
Amyloid beta threads in the fabric of Alzheimer's disease
-
Kisilevsky R (1998) Amyloid beta threads in the fabric of Alzheimer's disease. Nat Med 4:772-773
-
(1998)
Nat Med
, vol.4
, pp. 772-773
-
-
Kisilevsky, R.1
-
3
-
-
0015277207
-
Quantitative studies on amyloid in the islets of Langerhans
-
Westermark P (1972) Quantitative studies on amyloid in the islets of Langerhans. Ups J Med Sci 77:91-94
-
(1972)
Ups J Med Sci
, vol.77
, pp. 91-94
-
-
Westermark, P.1
-
4
-
-
0023222388
-
Islet amyloid in type 2 human diabetes mellitus and adult diabetic cats contains a novel putative polypeptide hormone
-
Westermark P, Wernstedt C, O'Brien TD, Hayden DW, Johnson KH (1987) Islet amyloid in type 2 human diabetes mellitus and adult diabetic cats contains a novel putative polypeptide hormone. Am J Pathol 127:414-417
-
(1987)
Am J Pathol
, vol.127
, pp. 414-417
-
-
Westermark, P.1
Wernstedt, C.2
O'Brien, T.D.3
Hayden, D.W.4
Johnson, K.H.5
-
5
-
-
0023579739
-
Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients
-
Cooper GJ, Willis AC, Clark A, Turner RC, Sim RB, Reid KB (1987) Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients. Proc Natl Acad Sci USA 84:8628-8632
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 8628-8632
-
-
Cooper, G.J.1
Willis, A.C.2
Clark, A.3
Turner, R.C.4
Sim, R.B.5
Reid, K.B.6
-
6
-
-
0025304242
-
Islet amyloid polypeptide in diabetic and non-diabetic Pima Indians
-
Clark A, Saad MF, Nezzer T et al. (1990) Islet amyloid polypeptide in diabetic and non-diabetic Pima Indians. Diabetologia 33:285-289
-
(1990)
Diabetologia
, vol.33
, pp. 285-289
-
-
Clark, A.1
Saad, M.F.2
Nezzer, T.3
-
7
-
-
0028598171
-
Pancreatic expression and secretion of human islet amyloid polypeptide in a transgenic mouse
-
D'Alessio DA, Verchere CB, Kahn SE et al. (1994) Pancreatic expression and secretion of human islet amyloid polypeptide in a transgenic mouse. Diabetes 43:1457-1461
-
(1994)
Diabetes
, vol.43
, pp. 1457-1461
-
-
D'Alessio, D.A.1
Verchere, C.B.2
Kahn, S.E.3
-
8
-
-
0027174446
-
Human islet amyloid polypeptide transgenic mice as a model of non-insulin-dependent diabetes mellitus (NDDM)
-
Fox N, Schrementi J, Nishi M et al. 1993 Human islet amyloid polypeptide transgenic mice as a model of non-insulin-dependent diabetes mellitus (NDDM). FEBS Lett 323:40-44
-
(1993)
FEBS Lett
, vol.323
, pp. 40-44
-
-
Fox, N.1
Schrementi, J.2
Nishi, M.3
-
9
-
-
0029742232
-
Treatment with growth hormone and dexamethasone in mice transgenic for human islet amyloid polypeptide causes islet amyloidosis and beta-cell dysfunction
-
Couce M, Kane LA, O'Brien TD et al. (1996) Treatment with growth hormone and dexamethasone in mice transgenic for human islet amyloid polypeptide causes islet amyloidosis and beta-cell dysfunction. Diabetes 45:1094-1101
-
(1996)
Diabetes
, vol.45
, pp. 1094-1101
-
-
Couce, M.1
Kane, L.A.2
O'Brien, T.D.3
-
10
-
-
0141780910
-
Extensive islet amyloid formation is induced by development of Type II diabetes mellitus and contributes to its progression: Pathogenesis of diabetes in a mouse model
-
Höppener JW, Oosterwijk C, Nieuwenhuis MG et al. (1999) Extensive islet amyloid formation is induced by development of Type II diabetes mellitus and contributes to its progression: pathogenesis of diabetes in a mouse model. Diabetologia 42:427-434
-
(1999)
Diabetologia
, vol.42
, pp. 427-434
-
-
Höppener, J.W.1
Oosterwijk, C.2
Nieuwenhuis, M.G.3
-
11
-
-
0029978228
-
Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide
-
Verchere CB, D'Alessio DA, Palmiter RD et al. (1996) Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide. Proc Natl Acad Sci USA 93:3492-3496
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 3492-3496
-
-
Verchere, C.B.1
D'Alessio, D.A.2
Palmiter, R.D.3
-
12
-
-
0031278270
-
Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition
-
Bales KR, Verina T, Dodel RC et al. (1997) Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition. Nat Genet 17:263-264
-
(1997)
Nat Genet
, vol.17
, pp. 263-264
-
-
Bales, K.R.1
Verina, T.2
Dodel, R.C.3
-
13
-
-
0033827557
-
Apolipoprotein E affects the amount, form, and anatomical distribution of amyloid beta-peptide deposition in homozygous APP(V717F) transgenic mice
-
Irizarry MC, Cheung BS, Rebeck GW, Paul SM, Bales KR, Hyman BT (2000) Apolipoprotein E affects the amount, form, and anatomical distribution of amyloid beta-peptide deposition in homozygous APP(V717F) transgenic mice. Acta Neuropathol (Berl) 100:451-458
-
(2000)
Acta Neuropathol (Berl)
, vol.100
, pp. 451-458
-
-
Irizarry, M.C.1
Cheung, B.S.2
Rebeck, G.W.3
Paul, S.M.4
Bales, K.R.5
Hyman, B.T.6
-
14
-
-
0029844205
-
Human apolipoprotein E: The Alzheimer's disease connection
-
Weisgraber KH, Mahley RW (1996) Human apolipoprotein E: the Alzheimer's disease connection. FASEB J 10:1485-1494
-
(1996)
FASEB J
, vol.10
, pp. 1485-1494
-
-
Weisgraber, K.H.1
Mahley, R.W.2
-
15
-
-
0027365822
-
Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease
-
Schmechel DE, Saunders AM, Strittmatter WJ et al. (1993) Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease. Proc Natl Acad Sci USA 90:9649-9653
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 9649-9653
-
-
Schmechel, D.E.1
Saunders, A.M.2
Strittmatter, W.J.3
-
16
-
-
0029839914
-
Apolipoprotein E is associated with islet amyloid and other amyloidoses: Implications for Alzheimer's disease
-
Charge SB, Esiri MM, Bethune CA, Hansen BC, Clark A (1996) Apolipoprotein E is associated with islet amyloid and other amyloidoses: implications for Alzheimer's disease. J Pathol 179:443-447
-
(1996)
J Pathol
, vol.179
, pp. 443-447
-
-
Charge, S.B.1
Esiri, M.M.2
Bethune, C.A.3
Hansen, B.C.4
Clark, A.5
-
17
-
-
0026592806
-
Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E
-
Zhang SH, Reddick RL, Piedrahita JA, Maeda N (1992) Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science 258:468-471
-
(1992)
Science
, vol.258
, pp. 468-471
-
-
Zhang, S.H.1
Reddick, R.L.2
Piedrahita, J.A.3
Maeda, N.4
-
18
-
-
0035514444
-
Islet amyloid develops diffusely throughout the pancreas before becoming severe and replacing endocrine cells
-
Wang F, Hull RL, Vidal J, Cnop M, Kahn SE (2001) Islet amyloid develops diffusely throughout the pancreas before becoming severe and replacing endocrine cells. Diabetes 50:2514-2520
-
(2001)
Diabetes
, vol.50
, pp. 2514-2520
-
-
Wang, F.1
Hull, R.L.2
Vidal, J.3
Cnop, M.4
Kahn, S.E.5
-
19
-
-
0033669527
-
Beta-cell glucokinase deficiency and hyperglycemia are associated with reduced islet amyloid deposition in a mouse model of type 2 diabetes
-
Andrikopoulos S, Verchere CB, Terauchi Y, Kadowaki T, Kahn SE (2000) Beta-cell glucokinase deficiency and hyperglycemia are associated with reduced islet amyloid deposition in a mouse model of type 2 diabetes. Diabetes 49:2056-2062
-
(2000)
Diabetes
, vol.49
, pp. 2056-2062
-
-
Andrikopoulos, S.1
Verchere, C.B.2
Terauchi, Y.3
Kadowaki, T.4
Kahn, S.E.5
-
20
-
-
0029985970
-
Development of sensitive immunoassays to detect amylin and amylin-like peptides in unextracted plasma
-
Percy AJ, Trainor DA, Rittenhouse J, Phelps J, Koda JE (1996) Development of sensitive immunoassays to detect amylin and amylin-like peptides in unextracted plasma. Clin Chem 42:576-585
-
(1996)
Clin Chem
, vol.42
, pp. 576-585
-
-
Percy, A.J.1
Trainor, D.A.2
Rittenhouse, J.3
Phelps, J.4
Koda, J.E.5
-
21
-
-
0034121607
-
Impaired superoxide production due to a deficiency in phagocyte NADPH oxidase fails to inhibit atherosclerosis in mice
-
Kirk EA, Dinauer MC, Rosen H, Chait A, Heinecke JW, LeBoeuf RC (2000) Impaired superoxide production due to a deficiency in phagocyte NADPH oxidase fails to inhibit atherosclerosis in mice. Arterioscler Thromb Vasc Biol 20:1529-1535
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 1529-1535
-
-
Kirk, E.A.1
Dinauer, M.C.2
Rosen, H.3
Chait, A.4
Heinecke, J.W.5
LeBoeuf, R.C.6
-
22
-
-
0033793584
-
Oophorectomy promotes islet amyloid formation in a transgenic mouse model of Type II diabetes
-
Kahn SE, Andrikopoulos S, Verchere CB, Wang F, Hull RL, Vidal J (2000) Oophorectomy promotes islet amyloid formation in a transgenic mouse model of Type II diabetes. Diabetologia 43:1309-1312
-
(2000)
Diabetologia
, vol.43
, pp. 1309-1312
-
-
Kahn, S.E.1
Andrikopoulos, S.2
Verchere, C.B.3
Wang, F.4
Hull, R.L.5
Vidal, J.6
-
23
-
-
0026725757
-
Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells
-
Plump AS, Smith JD, Hayek T et al. (1992) Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell 71:343-353
-
(1992)
Cell
, vol.71
, pp. 343-353
-
-
Plump, A.S.1
Smith, J.D.2
Hayek, T.3
-
24
-
-
0035907265
-
Identification of a heparin binding domain in the N-terminal cleavage site of pro-islet amyloid polypeptide. Implications for islet amyloid formation
-
Park K, Verchere CB (2001) Identification of a heparin binding domain in the N-terminal cleavage site of pro-islet amyloid polypeptide. Implications for islet amyloid formation. J Biol Chem 276:16611-16616
-
(2001)
J Biol Chem
, vol.276
, pp. 16611-16616
-
-
Park, K.1
Verchere, C.B.2
-
25
-
-
0032064203
-
The pathogenesis of amyloidosis: Understanding general principles
-
Westermark P (1998) The pathogenesis of amyloidosis: understanding general principles. Am J Pathol 152:1125-1127
-
(1998)
Am J Pathol
, vol.152
, pp. 1125-1127
-
-
Westermark, P.1
-
26
-
-
0033593027
-
Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease
-
Bales KR, Verina T, Cummins DJ et al. (1999) Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease. Proc Natl Acad Sci USA 96:15233-15238
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 15233-15238
-
-
Bales, K.R.1
Verina, T.2
Cummins, D.J.3
-
27
-
-
0028305380
-
Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease
-
Corder EH, Saunders AM, Risch NJ et al. (1994) Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease. Nat Genet 7:180-184
-
(1994)
Nat Genet
, vol.7
, pp. 180-184
-
-
Corder, E.H.1
Saunders, A.M.2
Risch, N.J.3
-
28
-
-
2142728495
-
Amyloid fibril formation is progressive and correlates with beta-cell secretion in transgenic mouse isolated islets
-
MacArthur DL, de Koning EJ, Verbeek JS, Morris JF, Clark A (1999) Amyloid fibril formation is progressive and correlates with beta-cell secretion in transgenic mouse isolated islets. Diabetologia 42:1219-1227
-
(1999)
Diabetologia
, vol.42
, pp. 1219-1227
-
-
MacArthur, D.L.1
De Koning, E.J.2
Verbeek, J.S.3
Morris, J.F.4
Clark, A.5
-
29
-
-
0029072551
-
Interactions of apolipoprotein E genotype, total cholesterol level, age, and sex in prediction of Alzheimer's disease: A case-control study
-
Jarvik GP, Wijsman EM, Kukull WA, Schellenberg GD, Yu C, Larson EB (1995) Interactions of apolipoprotein E genotype, total cholesterol level, age, and sex in prediction of Alzheimer's disease: a case-control study. Neurology 45:1092-1096
-
(1995)
Neurology
, vol.45
, pp. 1092-1096
-
-
Jarvik, G.P.1
Wijsman, E.M.2
Kukull, W.A.3
Schellenberg, G.D.4
Yu, C.5
Larson, E.B.6
-
30
-
-
0034711714
-
The association between APOE and dementia does not seem to be mediated by vascular factors
-
Prince M, Lovestone S, Cervilla J et al. (2000) The association between APOE and dementia does not seem to be mediated by vascular factors. Neurology 54:397-402
-
(2000)
Neurology
, vol.54
, pp. 397-402
-
-
Prince, M.1
Lovestone, S.2
Cervilla, J.3
-
31
-
-
0029671454
-
Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein
-
Bodovitz S, Klein WL (1996) Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein. J Biol Chem 271:4436-4440
-
(1996)
J Biol Chem
, vol.271
, pp. 4436-4440
-
-
Bodovitz, S.1
Klein, W.L.2
-
32
-
-
0035143161
-
Naturally occurring and experimental diabetes in cynomolgus monkeys: A comparison of carbohydrate and lipid metabolism and islet pathology
-
Wagner JD, Cline JM, Shadoan MK, Bullock BC, Rankin SE, Cefalu WT (2001) Naturally occurring and experimental diabetes in cynomolgus monkeys: a comparison of carbohydrate and lipid metabolism and islet pathology. Toxicol Pathol 29:142-148
-
(2001)
Toxicol Pathol
, vol.29
, pp. 142-148
-
-
Wagner, J.D.1
Cline, J.M.2
Shadoan, M.K.3
Bullock, B.C.4
Rankin, S.E.5
Cefalu, W.T.6
-
33
-
-
0034685763
-
Glucose regulates islet amyloid polypeptide gene transcription in a PDX-1 and calcium-dependent manner
-
Macfarlane WM, Campbell SC, Elrick LJ et al. (2000) Glucose regulates islet amyloid polypeptide gene transcription in a PDX-1 and calcium-dependent manner. J Biol Chem 275:15330-15335
-
(2000)
J Biol Chem
, vol.275
, pp. 15330-15335
-
-
Macfarlane, W.M.1
Campbell, S.C.2
Elrick, L.J.3
-
34
-
-
0028059279
-
Intra- and extracellular amyloid fibrils are formed in cultured pancreatic islets of transgenic mice expressing human islet amyloid polypeptide
-
Koning EJ de, Morris ER, Hofhuis FM et al. (1994) Intra- and extracellular amyloid fibrils are formed in cultured pancreatic islets of transgenic mice expressing human islet amyloid polypeptide. Proc Natl Acad Sci USA 91:8467-8471
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 8467-8471
-
-
De Koning, E.J.1
Morris, E.R.2
Hofhuis, F.M.3
-
35
-
-
0025773074
-
Apolipoprotein E allele frequencies in non-insulin-dependent diabetes mellitus with hypertriglyceridemia (type IIb, III, IV, and V hyperlipoproteinemia)
-
Eto M, Watanabe K, Makino I, Ishii K (1991) Apolipoprotein E allele frequencies in non-insulin-dependent diabetes mellitus with hypertriglyceridemia (type IIb, III, IV, and V hyperlipoproteinemia). Metabolism 40:776-780
-
(1991)
Metabolism
, vol.40
, pp. 776-780
-
-
Eto, M.1
Watanabe, K.2
Makino, I.3
Ishii, K.4
-
36
-
-
0033956223
-
Apolipoprotein E polymorphism in non-insulin-dependent diabetics of Mumbai, India and its effect on plasma lipids and lipoproteins
-
Inamdar PA, Kelkar SM, Devasagayam TP, Bapat MM (2000) Apolipoprotein E polymorphism in non-insulin-dependent diabetics of Mumbai, India and its effect on plasma lipids and lipoproteins. Diabetes Res Clin Pract 47:217-223
-
(2000)
Diabetes Res Clin Pract
, vol.47
, pp. 217-223
-
-
Inamdar, P.A.1
Kelkar, S.M.2
Devasagayam, T.P.3
Bapat, M.M.4
-
37
-
-
0022978831
-
Immunoreactive apolipoprotein E is a widely distributed cellular protein. Immunohistochemical localization of apolipoprotein E in baboon tissues
-
Lin CT, Xu YF, Wu JY, Chan L (1986) Immunoreactive apolipoprotein E is a widely distributed cellular protein. Immunohistochemical localization of apolipoprotein E in baboon tissues. J Clin Invest 78:947-958
-
(1986)
J Clin Invest
, vol.78
, pp. 947-958
-
-
Lin, C.T.1
Xu, Y.F.2
Wu, J.Y.3
Chan, L.4
-
38
-
-
0030119727
-
Immunohistochemical study on the deposition of apolipoprotein E in cerebral and islet amyloidoses in cynomolgus monkeys (Macaca fascicularis)
-
Nakamura S, Kiatipattanasakul W, Nakayama H et al. (1996) Immunohistochemical study on the deposition of apolipoprotein E in cerebral and islet amyloidoses in cynomolgus monkeys (Macaca fascicularis). Exp Anim 45:199-203
-
(1996)
Exp Anim
, vol.45
, pp. 199-203
-
-
Nakamura, S.1
Kiatipattanasakul, W.2
Nakayama, H.3
-
39
-
-
0029002233
-
Deposition of apolipoproteins E and J in senile plaques is topographically determined in both Alzheimer's disease and Down's syndrome brain
-
Kida E, Choi-Miura NH, Wisniewski KE (1995) Deposition of apolipoproteins E and J in senile plaques is topographically determined in both Alzheimer's disease and Down's syndrome brain. Brain Res 685:211-216
-
(1995)
Brain Res
, vol.685
, pp. 211-216
-
-
Kida, E.1
Choi-Miura, N.H.2
Wisniewski, K.E.3
-
41
-
-
0024574009
-
A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve
-
Boyles JK, Zoellner CD, Anderson LJ et al. (1989) A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve. J Clin Invest 83:1015-1031
-
(1989)
J Clin Invest
, vol.83
, pp. 1015-1031
-
-
Boyles, J.K.1
Zoellner, C.D.2
Anderson, L.J.3
-
42
-
-
0035102386
-
Augmented senile plaque load in aged female beta-amyloid precursor protein-transgenic mice
-
Callahan MJ, Lipinski WJ, Bian F, Durham RA, Pack A, Walker LC (2001) Augmented senile plaque load in aged female beta-amyloid precursor protein-transgenic mice. Am J Pathol 158:1173-1177
-
(2001)
Am J Pathol
, vol.158
, pp. 1173-1177
-
-
Callahan, M.J.1
Lipinski, W.J.2
Bian, F.3
Durham, R.A.4
Pack, A.5
Walker, L.C.6
-
43
-
-
0030684085
-
A beta amyloidogenesis: Unique, or variation on a systemic theme?
-
Kisilevsky R, Fraser PE (1997) A beta amyloidogenesis: unique, or variation on a systemic theme? Crit Rev Biochem Mol Biol 32:361-404
-
(1997)
Crit Rev Biochem Mol Biol
, vol.32
, pp. 361-404
-
-
Kisilevsky, R.1
Fraser, P.E.2
|