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Volumn 63, Issue 42, 2007, Pages 10407-10414

Simplified analogues of qinghaosu (artemisinin)

Author keywords

Antimalarials; Cyclization; Hemiketals; Heterocycles; Peroxides

Indexed keywords

ARTEMISININ; MERCURY;

EID: 34548362124     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2007.08.018     Document Type: Article
Times cited : (11)

References (68)
  • 1
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    • See: e.g.
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    • Klayman D.L. Science 228 (1985) 1049-1055
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    • Klayman, D.L.1
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    • 34548366071 scopus 로고    scopus 로고
    • Ref. 2i;
  • 64
    • 34548333190 scopus 로고    scopus 로고
    • 1H NMR (cf. Section 4).
  • 65
    • 34548350905 scopus 로고    scopus 로고
    • 2. See, e.g.:
  • 68
    • 27744592680 scopus 로고    scopus 로고
    • 1H NMR of 8 was very clean, suggesting presence of only one diastereomer. However, the information in 1D and 2D NMR did not allow for assignment of the relative configuration. Note that there have been reports that the antimalarial potency of peroxide antimalarial is not affected by stereochemistry. See, e.g.:
    • 1H NMR of 8 was very clean, suggesting presence of only one diastereomer. However, the information in 1D and 2D NMR did not allow for assignment of the relative configuration. Note that there have been reports that the antimalarial potency of peroxide antimalarial is not affected by stereochemistry. See, e.g.:. O'Neill P.M., Rawe S.L., Borstnik K., Miller A., Ward S.A., Bray P.G., Davies J., Oh C.H., Gary H., and Posner G.H. ChemBioChem 6 (2005) 2048-2054
    • (2005) ChemBioChem , vol.6 , pp. 2048-2054
    • O'Neill, P.M.1    Rawe, S.L.2    Borstnik, K.3    Miller, A.4    Ward, S.A.5    Bray, P.G.6    Davies, J.7    Oh, C.H.8    Gary, H.9    Posner, G.H.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.