Involvement of protein kinase B/AKT in early development of mouse fertilized eggs

Biology of Reproduction

Volumn 77, Issue 3, 2007, Pages 560-568

  Feng, Chen ^a   Yu, Aiming ^a   Liu, Ying ^a   Zhang, Jie ^a   Zong, Zhihong ^a   Su, Wenhui ^a   Zhang, Zhe ^a   Yu, Dahai ^a   Sun, Qing Yuan ^b   Yu, Bingzhi ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b INSTITUTE OF ZOOLOGY   (China)

Author keywords

AKT; CDC25B; Early development; Embryo; Kinases; M phase promoting factor; Mouse; Signal transduction

Indexed keywords

MATURATION PROMOTING FACTOR; MESSENGER RNA; PROTEIN KINASE B;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIVISION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; FERTILIZATION; MICROINJECTION; MITOSIS; MOUSE; MYRISTYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; WILD TYPE;

ANIMALS; CDC2 PROTEIN KINASE; DNA; EMBRYONIC DEVELOPMENT; FEMALE; MALE; MATURATION-PROMOTING FACTOR; MICE; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; PREGNANCY; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; ZYGOTE;

EID: 34548284351     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod.107.060269     Document Type: Article

References (69)

1. Kim N. Putting the cell cycle in order. Science 1996; 274:1643-1645.
2. Dunphy WG, Brizuela L, Beach D, Newport J. The Xenopus Cdc2 protein is a component of MPF, a cytoplasmic regulator of mitosis. Cell 1988; 54: 424-432.
3. Gautier J, Norbury C, Lohka MJ, Nurse P, Maller J. Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene Cdc2. Cell 1988; 54:433-439.
4. Hunt T. Maturation-promoting factor, cyclin, and the control of M-phase. Curr Opin Cell Biol 1989; 1:268-274.
5. Labbe JC, Picard A, Peaucellier G, Cavadore JC, Nurse P, Doree M. Purification of MPF from starfish identification as H1 histone kinase p34cdc2 and a possible mechanism for its periodic activation. Cell 1989; 57:253-256.
6. Murray AW, Kirschner MW. Cyclin synthesis drives the early embryonic cell cycle. Nature 1989; 339:275-280.
7. Coleman TR, Dunphy WG. Cdc2 regulatory factors. Curr Opin Cell Biol 1994; 6:877-882.
8. Mueller PR, Coleman TR, Kumagai A, Dunphy WG. Myt1: a membrane-associated inhibitory kinase that phosphorylates Cdc2 on both threonine-14 and tyrosine-15. Science 1995; 270:86-90.
9. Mueller PR, Coleman TR, Dunphy WG. Cell cycle regulation of a Xenopus Weel-like kinase. Mol Biol Cell 1995; 6:119-134.
10. Solomon MJ, Glotzer M, Lee TH, Philippe M, Kirschner MW. Cyclin activation of p34cdc2. Cell 1990; 63:1013-1024.
11. Strausfeld U, Labbé JC, Fesquet D, Cavadore JC, Picard A, Sadhu K, Russell P, Dorée M. Dephosphorylation and activation of a p34cdc2/cyclin B complex in vitro by human CDC25 protein. Nature 1991; 351:242-245.
12. Millar JBA, Russell P. The cdc25 M-phase inducer: an unconventional protein phosphatase. Cell 1992; 68:407-410.
13. King RW, Jackson P K, Kirschner MW. Mitosis in transition. Cell 1994; 79:563-571.
14. Dunphy WG. The decision to enter mitosis. Trends Cell Biol 1994; 4:202-207.
15. Chang F, Lee JT, Navolanic PM, Steelman LS, Shelton JG, Blalock WL, Franklin RA, McCubrey JA. Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy. Leukemia 2003; 17:590-603.
16. Fujita N, Sato S, Katayama K, Tsuruo T. Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization. J Biol Chem 2002; 277:28706-28713.
17. Liang J, Petrocelli JT, Kotchetkov R, Connor MK, Han K, Lee JH, Ciarallo S, Catzavelos C, Beniston R, Franssen E, Slingerland JM. PKB/ Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest. Nat Med 2002; 8:1153-1160.
18. Kip1. EMBO J 2004; 23: 1934-1942.
19. Kip1 at threonine 157 and modulation of its cellular localization. Nat Med 2002; 8: 1145-1152.
20. Kip1 by PKB/Akt-mediated phosphorylation in breast cancer. Nat Med 2002; 8:1136-1144.
21. Cip1/Waf1 by Akt-induced phosphorylation in HER-2/ neu-overexpressing cells. Nat Cell Biol 2001; 3:245-252.
22. Kandel ES, Skeen J, Majewski N, Cristofano AD, Pandolfi PP, Feliciano CS, Gartel A, Hay N. Activation of Akt/protein kinase B overcomes a G2/ M cell cycle checkpoint induced by DNA damage. Mol Cell Biol 2002; 22:7831-7841.
23. Okumura E, Fukuhara T, Yoshida H, Hanada S, Kozutsumi R, Mori M, Tachibana K, Kishimoto T. Akt inhibits Myt1 in the signaling pathway that leads to meiotic G2/M-phase transition. Nat Cell Biol 2002; 4:111-116.
24. Kazuhiro K, Naoya F, Takashi T. Akt/protein kinase B-dependent phosphorylation and inactivation of Wee1 Hu promote cell cycle progression at G2/M transition. Mol Cell Biol 2005; 25:5725-5737.
25. Hogan B, Constantini LE. Manipulating the mouse embryos: A laboratory manual. New York: Cold Harbor Laboratory Press; 1986:249-256.
26. Alessi DR, Andjelkovic M, Caudwell B, Cron P, Morrice N, Cohen P, Hemmings BA. Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J 1996; 15:6541-6551.
27. Faiyaz A, Li-Na C, Lena SH, Ling-Mei W, Tova RL, Jaclyn HP, Michael JQ, Eva D, Vincent CM. Cyclic nucleotide phosphodiesterase 3B is a downstream target of protein kinase B and may be involved in regulation of effects of protein kinase B on thymidine incorporation in FDCP2 cells. J Immunol 2000; 164:4678-4688.
28. Gallicano GI, McGaughey RW, Capco DG. Activation of protein kinase C after fertilization is required for remodeling the mouse egg into the zygote. Mol Reprod Dev 1997; 46:587-601.
29. Aimee DK, Fumito T, Richard AR. Akt, a Pleckstrin Homology domain containing kinase, is activated primarily by phosphorylation. J Biol Chem 1996; 271:21920-21926.
30. Datta K, Bellacosa A, Chan TO, Tsichlis PN. Akt is a direct target of the phophatidylinositol 3-kinase: activation by growth factors, v-src and v-Haras, in Sf9 and mammalian cells. J Biol Chem 1996; 271:30835-30839.
31. Klippel A, Reinhard C, Kavanaugh MW, Apell G, Escobedo MA, Williams LT. Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways. Mol Cell Biol 1996; 16:4117-4127.
32. Cong LN, Chen H, Li Y, Zhou L, McGibbon MA, Taylor SI, Quon MJ. Physiological role of Akt in insulin-stimulated translocation of GLUT4 in transfected rat adipose cells. Mol Endocrinol 1997; 11:1881-1890.
33. Lee SR, Park JH, Park EK, Chung CH, Kang SS, Bang OS. Akt-induced promotion of cell-cycle progression at G2/M phase involves upregulation of NF-Y binding activity in PC12 cells. J Cell Physiol 2005; 205:270-277.
34. Watanabe S, Umehara H, Murayama K, Okabe M, Kimura T, Nakano T. Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells. Oncogene 2006; 25:2697-2707.
35. Nilsson I, Hoffmann I. Cell cycle regulation by the Cdc25 phosphatase family. Prog Cell Cycle Res 2000; 4:107-114.
36. Hoffmann I, Clarke P, Marcote MJ, Karsenti E, Draetta G. Phosphorylation and activation of human cdc25-C by cdc2-cyclin B and its involvement in the self amplification of MPF at mitosis. EMBO J 1993; 12:53-63.
37. Kumagai A, Dunphy W. Regulation of the cdc25 protein during the cell cycle in Xenopus extracts. Cell 1992; 70:139-151.
38. Baldin V, Theis-Febvre N, Benne C, Froment C, Cazales M, Burlet-Schiltz O, Ducommun B. PKB/Akt phosphorylates the Cdc25B phosphatase and regulates its intracellular localization. Biol Cell 2003; 95:547-554.
39. Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 1995; 378:785-789.
40. Duble BW, Woodgett JR. GSK-3: tricks of the trade for a multi-tasking kinase. J Cell Sci 2003; 116:1175-1186.
41. Papadopoulou D, Bianchi MW, Bourouis M. Functional studies of shaggy/ glycogen synthase kinase 3 phosphorylation sites in Drosophila melanogaster. Mol Cell Biol 2004; 24:4909-4919.
42. Edward JM, Kei S, Laura JA, Leah R, Natalia S, Rodolfo M, Dario RA. Role that phosphorylation of GSK3 plays in insulin and Wnt signaling defined by knockin analysis. EMBO J 2005; 24:1571-1583.
43. Yu B, Zheng J, Yu AM, Shi XY, Liu Y, Wu DD, Fu W, Yang J. Effects of protein kinase C on M-phase promoting factor in early development of fertilized mouse eggs. Cell Biochem Funct 2004; 22:291-298.
44. Yu B, Wang Y, Liu Y, Liu Y, Li X, Wu DD, Zong Z, Zhang J, Yu D. Protein kinase A regulates cell cycle progression of mouse fertilized eggs by means of MPF. Dev Dyn 2005; 232:98-105.
45. Kalous J, Solc P, Baran V, Kubelka M, Schultz RM, Motlik J. PKB/AKT is involved in resumption of meiosis in mouse oocytes. Biol Cell 2006; 98: 111-123.
46. Patrick S, Magali LB, Julia M, Robert B, Sandrine B, Odile ML, Partrick C. Signal transduction pathways that contribute to CDC2A/cyclin B activation during the first mitotic division in sea urchin embryos. Exp Cell Res 2004; 296:347-357.
47. Gabrielli BG, Clark JM, McCormack AK, Ellem KA. Hyperphosphorylation of the N-terminal domain of Cdc25 regulates activity toward cyclin B1/Cdc2 but not cyclin A/Cdk2. J Biol Chem 1997; 272:28607-28614.
48. Gabrielli BG, Clark JM, McCormack AK, Ellem KA. Ultraviolet light-induced G2 phase cell cycle checkpoint blocks cdc25-dependent progression into mitosis. Oncogene 1997; 15:749-758.
49. Lammer C, Wagerer S, Saffrich R, Mertens D, Ansorge W, Hoffmann I. The cdc25B phosphatase is essential for the G2/M phase transition in human cells. J Cell Sci 1998; 111:2445-2453.
50. Karlsson C, Katich S, Hagting A, Hoffmann I, Pines J. Cdc25B and Cdc25C differ markedly in their properties as initiators of mitosis. J Cell Biol 1999; 146:573-584.
51. Goldstone S, Pavey S, Forrest A, Sinnamon J, Gabrielli B. Cdc25-dependent activation of cyclin A/cdk2 is blocked in G2 phase arrested cells independently of ATM/ATR. Oncogene 2001; 20:921-932.
52. Baldin V, Cans C, Knibiehler M, Ducommun B. Phosphorylation of human CDC25B phosphatase by CDC2A-cyclin A triggers its proteasome dependent degradation. J Biol Chem 1997; 272:32731-32734.
53. Bulavin DV, Amundson SA, Fornace AJ. p38 and Chk1 kinases: different conductors for the G(2)/M checkpoint symphony. Curr Opin Genet Dev 2002; 12:92-97.
54. Cazales M, Schmitt E, Montembault E, Dozier C, Prigent C, Ducommun B. CDC25B phosphorylation by Aurora-A occurs at the G2/M transition and is inhibited by DNA damage. Cell Cycle 2005; 4:1233-1238.
55. Lindqvist A, Kallstrom H, Karlsson RC. Characterisation of Cdc25B localization and nuclear export during the cell cycle and in response to stress. J Cell Sci 2004; 117:4979-4990.
56. Manke IA, Nguyen A, Lim D, Stewart MQ, Elia AE, Yaffe MB. MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/ M transition and S phase progression in response to UV irradiation. Mol Cell 2005; 17:37-48.
57. Mirey G, Chartrain I, Froment C, Quaranta M, Bouche JP, Monsarrat B, Tassan JP, Ducommun B. CDC25B phosphorylated by pEg3 localizes to the centrosome and the spindle poles at mitosis. Cell Cycle 2005; 4: 806-811.
58. Theis FN, Filhol O, Froment C, Cazales M, Cochet C, Monsarrat B, Ducommun B, Baldin V. Protein kinase CK2 regulates CDC25B phosphatase activity. Oncogene 2003; 22:220-232.
59. Davezac N, Baldin V, Gabrielli B, Forrest A, Theis-Febvre N, Yashida M, Ducommun B. Regulation of CDC25B phosphatases subcellular localization. Oncogene 2000; 19:2179-2185.
60. Forrest A, Gabrielli B. Cdc25B activity is regulated by 14-3-3. Oncogene 2001; 20:4393-4401.
61. Giles N, Forrest A, Gabrielli B. 14-3-3 acts as an intramolecular bridge to regulate cdc25B localization and activity. J Biol Chem 2003; 278:28580-28587.
62. Mils V, Baldin V, Pinta I, Goubin F, Papin C, Waye M, Eychene A, Ducommun B. Specific interaction between 14-3-3 isoforms and the human CDC25B phosphatase. Oncogene 2000; 19:1257-1265.
63. Gabrielli BG, De Souza CP, Tonks ID, Clark JM, Hayward NK, Ellem KA. Cytoplasmic accumulation of cdc25B phosphatase in mitosis triggers centrosomal microtubule nucleation in HeLa cells. J Cell Sci 1996; 109: 1081-1093.
64. Jackman M, Lindon C, Nigg EA, Pines J. Active cyclin B1-Cdk1 first appears on centrosomes in prophase. Nat Cell Biol 2003; 5:143-148.
65. Lindqvist A, Kallstrom A, Lundgren A, Barsoium E, Rosenthal CK. Cdc25B cooperates with Cdc25A to induce mitosis but has a unique role in activating cyclin B1-Cdk1 at the centrosome. J Cell Biol 2005; 171: 35-45.
66. Kramer A, Lukas J, Bartek J. Checking out the centrosome. Cell Cycle 2004; 3:1390-1393.
67. Dutertre S, Cazales M, Quaranta M, Froment C, Trabut V, Dozier C, Mirey G, Bouche JP, Theis-Febvre N, Schmitt E, Monsarrat B, Prigent C, Ducommun B. Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2-M transition. J Cell Sci 2004; 117: 2523-2531.
68. Kramer A, Mailand N, Lukas C, Syljuasen RG, Wilkinson CJ, Nigg EA, Bartek J, Lukas J. Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase. Nat Cell Biol 2004; 6:884-891.
69. Wakefield JG, Stephens DJ, Tavare JM. A role for glycogen synthase kinase-3 in mitotic spindle dynamics and chromosome alignment. J Cell Sci 2003; 116:637-646.