-
1
-
-
16244393685
-
Signalling by PI3K isoforms: Insights from gene-targeted mice
-
Vanhaesebroeck B, Ali K, Bilancio A, Geering B, Foukas LC. Signalling by PI3K isoforms: Insights from gene-targeted mice. Trends Biochem Sci 2005; 30:194-204.
-
(2005)
Trends Biochem Sci
, vol.30
, pp. 194-204
-
-
Vanhaesebroeck, B.1
Ali, K.2
Bilancio, A.3
Geering, B.4
Foukas, L.C.5
-
2
-
-
33644517238
-
Phosphoinositide 3-kinase controls early and late events in mammalian cell division
-
Garcia Z, Kumar A, Marques M, Cortes I, Carrera AC. Phosphoinositide 3-kinase controls early and late events in mammalian cell division. EMBO J 2006; 25:655-61.
-
(2006)
EMBO J
, vol.25
, pp. 655-661
-
-
Garcia, Z.1
Kumar, A.2
Marques, M.3
Cortes, I.4
Carrera, A.C.5
-
3
-
-
0036829983
-
The p85 regulatory subunit controls sequential activation of phosphoinositide 3-kinase by Tyr kinases and Ras
-
Jimenez C, Hernandez C, Pimentel B, Carrera AC. The p85 regulatory subunit controls sequential activation of phosphoinositide 3-kinase by Tyr kinases and Ras. J Biol Chem 2002; 277:41556-62.
-
(2002)
J Biol Chem
, vol.277
, pp. 41556-41562
-
-
Jimenez, C.1
Hernandez, C.2
Pimentel, B.3
Carrera, A.C.4
-
4
-
-
0035150990
-
Growth-factor-dependent mitogenesis requires two distinct phases of signalling
-
Jones SM, Kazlauskas A. Growth-factor-dependent mitogenesis requires two distinct phases of signalling. Nat Cell Biol 2001; 3:165-72.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 165-172
-
-
Jones, S.M.1
Kazlauskas, A.2
-
6
-
-
0036467497
-
Regulation of Ras signaling by the cell cycle
-
Stacey D, Kazlauskas A. Regulation of Ras signaling by the cell cycle. Curr Opin Genet Dev 2002; 12:44-46.
-
(2002)
Curr Opin Genet Dev
, vol.12
, pp. 44-46
-
-
Stacey, D.1
Kazlauskas, A.2
-
7
-
-
0032905924
-
c-Myc target genes involved in cell growth, apoptosis and metabolism
-
Dang CV. c-Myc target genes involved in cell growth, apoptosis and metabolism. Mol Cell Biol 1999; 19:1-11.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 1-11
-
-
Dang, C.V.1
-
9
-
-
0032996623
-
c-Myc regulates Cyclin D-Cdk4 and Cdk6 activity but affects cell cycle progression at multiple independent points
-
Mateyak MK, Obaya AJ, Sedivy JM. c-Myc regulates Cyclin D-Cdk4 and Cdk6 activity but affects cell cycle progression at multiple independent points. Mol Cell Biol 1999; 19:4672-83.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 4672-4683
-
-
Mateyak, M.K.1
Obaya, A.J.2
Sedivy, J.M.3
-
10
-
-
0037103988
-
-
1/S transition in mouse ES cells. Oncogene 2002;21:5515-28. Oncogene 2002; 5515-28.
-
1/S transition in mouse ES cells. Oncogene 2002;21:5515-28. Oncogene 2002; 5515-28.
-
-
-
-
11
-
-
0029002136
-
A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins
-
Littlewood TD, Hancock DC, Danielian PS, Parker MG, Evan GI. A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins. Nucleic Acids Res 1995; 23:1686-90.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 1686-1690
-
-
Littlewood, T.D.1
Hancock, D.C.2
Danielian, P.S.3
Parker, M.G.4
Evan, G.I.5
-
12
-
-
0026099022
-
The MYC protein activates transcription of the alpha-prothymosin gene
-
Eilers M, Schirm S, Bishop JM. The MYC protein activates transcription of the alpha-prothymosin gene. EMBO J 1991; 10:133-41.
-
(1991)
EMBO J
, vol.10
, pp. 133-141
-
-
Eilers, M.1
Schirm, S.2
Bishop, J.M.3
-
14
-
-
3543028648
-
Myc-induced proliferation and transformation require Akt-mediated phosphorylation of FoxO proteins
-
Bouchard C, Marquardt J, Bras A, Medema RH, Eilers M. Myc-induced proliferation and transformation require Akt-mediated phosphorylation of FoxO proteins. EMBO J 2004; 23:2830-40.
-
(2004)
EMBO J
, vol.23
, pp. 2830-2840
-
-
Bouchard, C.1
Marquardt, J.2
Bras, A.3
Medema, R.H.4
Eilers, M.5
-
15
-
-
0035912763
-
Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis
-
Bowman T, Broome MA, Sinibaldi D, Wharton W, Pledger WJ, Sedivy JM, Irby R, Yeatman T, Courtneidge SA, Jove R. Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis. Proc Natl Acad Sci USA 2001; 98:7319-24.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 7319-7324
-
-
Bowman, T.1
Broome, M.A.2
Sinibaldi, D.3
Wharton, W.4
Pledger, W.J.5
Sedivy, J.M.6
Irby, R.7
Yeatman, T.8
Courtneidge, S.A.9
Jove, R.10
-
16
-
-
0032518916
-
Regulation of c-myc expression by Ras/Raf signalling
-
Kerkhoff E, Houben R, Löffler S, Troppmair J, Lee JE, Rapp UR. Regulation of c-myc expression by Ras/Raf signalling. Oncogene 1998; 16:211-16.
-
(1998)
Oncogene
, vol.16
, pp. 211-216
-
-
Kerkhoff, E.1
Houben, R.2
Löffler, S.3
Troppmair, J.4
Lee, J.E.5
Rapp, U.R.6
-
19
-
-
13944252067
-
The life cycle of C-Myc
-
Sears RC. The life cycle of C-Myc. Cell cycle 2004; 3:1133-37.
-
(2004)
Cell cycle
, vol.3
, pp. 1133-1137
-
-
Sears, R.C.1
-
20
-
-
23844469503
-
Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants
-
Hemann MT, Bric A, Teruya-Feldstein J, Herbst A, Nilsson JA, Cordon-Cardo C, Cleveland JL, Tansey WP, Lowe SW. Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants. Nature 2005; 436:807-11.
-
(2005)
Nature
, vol.436
, pp. 807-811
-
-
Hemann, M.T.1
Bric, A.2
Teruya-Feldstein, J.3
Herbst, A.4
Nilsson, J.A.5
Cordon-Cardo, C.6
Cleveland, J.L.7
Tansey, W.P.8
Lowe, S.W.9
-
21
-
-
0036632368
-
The PI3K AKT pathway in human cancer
-
Vivanco I, Sawyers CL. The PI3K AKT pathway in human cancer. Nat Rev Cancer 2002; 2:489-501.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
22
-
-
0034676001
-
Role of the PI3K regulatory subunit in the control of Actin organization and cell migration
-
Jimenez C, Portela RA, Mellado M, Rodriguez-Frade JM, Collard J, Serrano A, Martinez-A C, Avila J, Carrera AC. Role of the PI3K regulatory subunit in the control of Actin organization and cell migration. J Cell Biol 2000; 151:249-62.
-
(2000)
J Cell Biol
, vol.151
, pp. 249-262
-
-
Jimenez, C.1
Portela, R.A.2
Mellado, M.3
Rodriguez-Frade, J.M.4
Collard, J.5
Serrano, A.6
Martinez-A, C.7
Avila, J.8
Carrera, A.C.9
-
23
-
-
0035909313
-
Forkhead transcription factors contribute to execution of the mitotic programme in mammals
-
Álvarez B, Martínez AC, Burgering BM, Carrera AC. Forkhead transcription factors contribute to execution of the mitotic programme in mammals. Nature 2001; 413:744-47.
-
(2001)
Nature
, vol.413
, pp. 744-747
-
-
Álvarez, B.1
Martínez, A.C.2
Burgering, B.M.3
Carrera, A.C.4
-
24
-
-
0037698271
-
PI3K activation regulates cell division time by coordinated control of cell mass and cell cycle progression rate
-
Álvarez B, Garrido F, Garcia-Sanz JA, Carrera AC. PI3K activation regulates cell division time by coordinated control of cell mass and cell cycle progression rate. J Biol Chem 2003; 278:26466-73.
-
(2003)
J Biol Chem
, vol.278
, pp. 26466-26473
-
-
Álvarez, B.1
Garrido, F.2
Garcia-Sanz, J.A.3
Carrera, A.C.4
-
25
-
-
0037018847
-
A role for PI3K and PKB activity in the G2/M phase of the cell cycle
-
Shtivelman E, Sussman J, Stokoe D. A role for PI3K and PKB activity in the G2/M phase of the cell cycle. Curr Biol 2002; 12:919-24.
-
(2002)
Curr Biol
, vol.12
, pp. 919-924
-
-
Shtivelman, E.1
Sussman, J.2
Stokoe, D.3
-
26
-
-
0038061468
-
Requirement for PI3K activity during progression through S-phase and entry into mitosis
-
Dangi S, Cha H, Shapiro P. Requirement for PI3K activity during progression through S-phase and entry into mitosis. Cell Signal 2003; 15:667-75.
-
(2003)
Cell Signal
, vol.15
, pp. 667-675
-
-
Dangi, S.1
Cha, H.2
Shapiro, P.3
-
27
-
-
33750218693
-
A PI3K activity-independent function of p85 regulatory subunit in control of mammalian cytokinesis
-
Garcia Z, Silio V, Marques M, Cortes I, Kumar A, Hernandez C, Checa AI, Serrano A, Carrera AC. A PI3K activity-independent function of p85 regulatory subunit in control of mammalian cytokinesis. EMBO J 2006; 25:4740-51.
-
(2006)
EMBO J
, vol.25
, pp. 4740-4751
-
-
Garcia, Z.1
Silio, V.2
Marques, M.3
Cortes, I.4
Kumar, A.5
Hernandez, C.6
Checa, A.I.7
Serrano, A.8
Carrera, A.C.9
-
28
-
-
0141541745
-
The role of Cdc42p GTPase-activating proteins in assembly of the Septin ring in yeast
-
Caviston JP, Longtine M, Pringle JR, Bi E. The role of Cdc42p GTPase-activating proteins in assembly of the Septin ring in yeast. Mol Biol Cell 2003; 14:4051-66.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 4051-4066
-
-
Caviston, J.P.1
Longtine, M.2
Pringle, J.R.3
Bi, E.4
-
29
-
-
0344825096
-
The Septins
-
Kinoshita M. The Septins. Genome Biol 2003; 4:236-45.
-
(2003)
Genome Biol
, vol.4
, pp. 236-245
-
-
Kinoshita, M.1
-
30
-
-
1942455757
-
Cdc42 and mDia3 regulate microtubule attachment to kinetocores
-
Yasuda S, Oceguera-Yanez F, Kato T, Okamoto M, Yonemura S, Terada Y, Ishizaki T, Narumiya S. Cdc42 and mDia3 regulate microtubule attachment to kinetocores. Nature 2004; 428:767-771.
-
(2004)
Nature
, vol.428
, pp. 767-771
-
-
Yasuda, S.1
Oceguera-Yanez, F.2
Kato, T.3
Okamoto, M.4
Yonemura, S.5
Terada, Y.6
Ishizaki, T.7
Narumiya, S.8
-
31
-
-
15244346231
-
A mitotic Septin scaffold required for Mammalian chromosome congression and segregation
-
Spiliotis ET, Kinoshita M, Nelson WJ. A mitotic Septin scaffold required for Mammalian chromosome congression and segregation. Science 2005; 307:1781-85.
-
(2005)
Science
, vol.307
, pp. 1781-1785
-
-
Spiliotis, E.T.1
Kinoshita, M.2
Nelson, W.J.3
-
32
-
-
0042672950
-
Activity of Rho-family GTPases during cell division as visualized with FRET-based probes
-
Yoshizaki H, Ohba Y, Kurokawa K, Itoh RE, Nakamura T, Mochizuki N, Nagashima K, Matsuda M. Activity of Rho-family GTPases during cell division as visualized with FRET-based probes. J Cell Biol 2003; 162:223-32.
-
(2003)
J Cell Biol
, vol.162
, pp. 223-232
-
-
Yoshizaki, H.1
Ohba, Y.2
Kurokawa, K.3
Itoh, R.E.4
Nakamura, T.5
Mochizuki, N.6
Nagashima, K.7
Matsuda, M.8
-
33
-
-
13844252076
-
Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis
-
Oceguera-Yanez F, Kimura K, Yasuda S, Higashida C, Kitamura T, Hiraoka Y, Haraguchi T, Narumiya S. Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis. J Cell Biol 2005; 168:221-232.
-
(2005)
J Cell Biol
, vol.168
, pp. 221-232
-
-
Oceguera-Yanez, F.1
Kimura, K.2
Yasuda, S.3
Higashida, C.4
Kitamura, T.5
Hiraoka, Y.6
Haraguchi, T.7
Narumiya, S.8
-
34
-
-
0036798406
-
The mammalian Septin MSF localizes with microtubules and is required for completion of cytokinesis
-
Surka MC, Tsang CW, Trimble WS. The mammalian Septin MSF localizes with microtubules and is required for completion of cytokinesis. Mol Biol Cell 2002; 13:3532-45.
-
(2002)
Mol Biol Cell
, vol.13
, pp. 3532-3545
-
-
Surka, M.C.1
Tsang, C.W.2
Trimble, W.S.3
-
35
-
-
0030943556
-
Nedd5, a mammalian Septin, is a novel cytoskeletal component interActing with Actin-based structures
-
Kinoshita M, Kumar S, Mizoguchi A, Ide C, Kinoshita A, Haraguchi T, Hiraoka Y, Noda M. Nedd5, a mammalian Septin, is a novel cytoskeletal component interActing with Actin-based structures. Genes Dev 1997; 11:1535-47.
-
(1997)
Genes Dev
, vol.11
, pp. 1535-1547
-
-
Kinoshita, M.1
Kumar, S.2
Mizoguchi, A.3
Ide, C.4
Kinoshita, A.5
Haraguchi, T.6
Hiraoka, Y.7
Noda, M.8
-
36
-
-
28544448876
-
The Caenorhabditis elegans ect-2 RhoGEF gene regulates cytokinesis and migration of epidermal P cells
-
Morita K, Hirono K, Han M. The Caenorhabditis elegans ect-2 RhoGEF gene regulates cytokinesis and migration of epidermal P cells. EMBO Rep 2005; 6:1163-68.
-
(2005)
EMBO Rep
, vol.6
, pp. 1163-1168
-
-
Morita, K.1
Hirono, K.2
Han, M.3
-
37
-
-
0036007115
-
Central spindle assembly and cytokinesis require a kinesin-like protein/RhoGAP complex with microtubule bundling activity
-
Mishima M, Kaitna S, Glotzer M. Central spindle assembly and cytokinesis require a kinesin-like protein/RhoGAP complex with microtubule bundling activity. Dev Cell 2002; 2:41-54.
-
(2002)
Dev Cell
, vol.2
, pp. 41-54
-
-
Mishima, M.1
Kaitna, S.2
Glotzer, M.3
-
38
-
-
13444311711
-
Concentric zones of active RhoA and Cdc42 around single cell wounds
-
Benink HA, Bement WM. Concentric zones of active RhoA and Cdc42 around single cell wounds. J Cell Biol 2005; 168:429-39.
-
(2005)
J Cell Biol
, vol.168
, pp. 429-439
-
-
Benink, H.A.1
Bement, W.M.2
-
39
-
-
0034643331
-
AFX-like Forkhead TF mediate cell-cycle regulation by Ras and PKB through p27kip1
-
Medema RH, Kops GJ, Bos JL, Burgering BM. AFX-like Forkhead TF mediate cell-cycle regulation by Ras and PKB through p27kip1. Nature 2000; 404:782-87.
-
(2000)
Nature
, vol.404
, pp. 782-787
-
-
Medema, R.H.1
Kops, G.J.2
Bos, J.L.3
Burgering, B.M.4
-
41
-
-
2342526543
-
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells
-
Yeh E, Cunningham M, Arnold H, Chasse D, Monteith T, Ivaldi G, Hahn WC, Stukenberg PT, Shenolikar S, Uchida T, Counter CM, Nevins JR, Means AR, Sears RA. A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells. Nat Cell Biol 2004; 6:308-18.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 308-318
-
-
Yeh, E.1
Cunningham, M.2
Arnold, H.3
Chasse, D.4
Monteith, T.5
Ivaldi, G.6
Hahn, W.C.7
Stukenberg, P.T.8
Shenolikar, S.9
Uchida, T.10
Counter, C.M.11
Nevins, J.R.12
Means, A.R.13
Sears, R.A.14
-
42
-
-
0032557646
-
Essential role for PKB in insulin-induced GSK3 inactivation: Characterization of dominant-negative mutant of PKB
-
van Weeren PC, de Bruyn KM, de Vries-Smits AM, van Lint J, Burgering BM. Essential role for PKB in insulin-induced GSK3 inactivation: Characterization of dominant-negative mutant of PKB. J Biol Chem 1998; 273:13150-56.
-
(1998)
J Biol Chem
, vol.273
, pp. 13150-13156
-
-
van Weeren, P.C.1
de Bruyn, K.M.2
de Vries-Smits, A.M.3
van Lint, J.4
Burgering, B.M.5
-
43
-
-
0642286488
-
The interaction of glycogen synthase kinase-3 (GSK-3) with the cell cycle
-
Ryves WJ, Harwood AJ. The interaction of glycogen synthase kinase-3 (GSK-3) with the cell cycle. Prog Cell Cycle Res 2003; 5:489-95.
-
(2003)
Prog Cell Cycle Res
, vol.5
, pp. 489-495
-
-
Ryves, W.J.1
Harwood, A.J.2
|