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Volumn 322, Issue 3, 2007, Pages 973-981

Reparixin, an inhibitor of CXCR2 function, attenuates inflammatory responses and promotes recovery of function after traumatic lesion to the spinal cord

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR2; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 2; METHYLPREDNISOLONE SODIUM SUCCINATE; PROTEIN; PROTEIN INHIBITOR; PROTEIN NG2; REPARIXIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 34548082787     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.107.123679     Document Type: Article
Times cited : (55)

References (41)
  • 2
    • 33645967159 scopus 로고    scopus 로고
    • Spontaneous locomotor recovery in spinal cord injured rats is accompanied by anatomical plasticity of reticulospinal fibers
    • Ballermann M and Fouad K (2006) Spontaneous locomotor recovery in spinal cord injured rats is accompanied by anatomical plasticity of reticulospinal fibers. Eur J Neurosci 23:1988-1996.
    • (2006) Eur J Neurosci , vol.23 , pp. 1988-1996
    • Ballermann, M.1    Fouad, K.2
  • 3
    • 0028919411 scopus 로고
    • A sensitive and reliable locomotor rating scale for open field testing in rats
    • Basso DM, Beattie MS, and Bresnahan JC (1995) A sensitive and reliable locomotor rating scale for open field testing in rats. J Neurotrauma 12:1-21.
    • (1995) J Neurotrauma , vol.12 , pp. 1-21
    • Basso, D.M.1    Beattie, M.S.2    Bresnahan, J.C.3
  • 6
    • 0036124519 scopus 로고    scopus 로고
    • Methylprednisolone and spinal cord injury
    • Bracken MB (2002) Methylprednisolone and spinal cord injury. J Neurosurg 96:140-141.
    • (2002) J Neurosurg , vol.96 , pp. 140-141
    • Bracken, M.B.1
  • 7
    • 27444442682 scopus 로고    scopus 로고
    • Neutrophil recruitment in the reperfused-injured rat liver was effectively attenuated by repertaxin, a novel allosteric noncompetitive inhibitor of CXCL8 receptors: A therapeutic approach for the treatment of post-ischemic hepatic syndromes
    • Cavalieri B, Mosca M, Ramadori P, Perrelli M, De Simone L, Colotta F, Bestini R, Poli G, and Cutrin JC (2005) Neutrophil recruitment in the reperfused-injured rat liver was effectively attenuated by repertaxin, a novel allosteric noncompetitive inhibitor of CXCL8 receptors: a therapeutic approach for the treatment of post-ischemic hepatic syndromes. Int J Immunopathol Pharmacol 18:475-486.
    • (2005) Int J Immunopathol Pharmacol , vol.18 , pp. 475-486
    • Cavalieri, B.1    Mosca, M.2    Ramadori, P.3    Perrelli, M.4    De Simone, L.5    Colotta, F.6    Bestini, R.7    Poli, G.8    Cutrin, J.C.9
  • 8
    • 0033652796 scopus 로고    scopus 로고
    • Leukocyte granule proteins mobilized innate host defenses and adaptive immune responses
    • Chertov O, Yang D, Oward OMZ, and Oppenheim JJ (2000) Leukocyte granule proteins mobilized innate host defenses and adaptive immune responses. Immunol Rev 177:68-75.
    • (2000) Immunol Rev , vol.177 , pp. 68-75
    • Chertov, O.1    Yang, D.2    Oward, O.M.Z.3    Oppenheim, J.J.4
  • 10
    • 0041624586 scopus 로고    scopus 로고
    • Methylprednisolone increases neuronal apoptosis during autoimmune CNS inflammation by inhibition of an endogenous neuroprotective pathway
    • Diem R, Hobom M, Maier K, Weissert R, Storch MK, Meyer R, and Bahr M (2003) Methylprednisolone increases neuronal apoptosis during autoimmune CNS inflammation by inhibition of an endogenous neuroprotective pathway. J Neurosci 23:6993-7000.
    • (2003) J Neurosci , vol.23 , pp. 6993-7000
    • Diem, R.1    Hobom, M.2    Maier, K.3    Weissert, R.4    Storch, M.K.5    Meyer, R.6    Bahr, M.7
  • 11
    • 18044387971 scopus 로고    scopus 로고
    • Methylprednisolone inhibits production of interleukin-1beta and interleukin-6 in the spinal cord following compression injury in rats
    • Fu ES and Saporta S (2005) Methylprednisolone inhibits production of interleukin-1beta and interleukin-6 in the spinal cord following compression injury in rats. J Neurosurg Anesthesiol 17:82-85.
    • (2005) J Neurosurg Anesthesiol , vol.17 , pp. 82-85
    • Fu, E.S.1    Saporta, S.2
  • 14
    • 0027463358 scopus 로고
    • Brain glia release factors with opposing actions upon neuronal survival
    • Giulian D, Vaca K, and Corpuz M (1993) Brain glia release factors with opposing actions upon neuronal survival. J Neurosci 13:29-37.
    • (1993) J Neurosci , vol.13 , pp. 29-37
    • Giulian, D.1    Vaca, K.2    Corpuz, M.3
  • 17
    • 0035074297 scopus 로고    scopus 로고
    • Temporal-spatial pattern of acute neuronal and glial loss after spinal cord contusion
    • Grossman SD, Rosenberg LJ, and Wrathall JR (2001) Temporal-spatial pattern of acute neuronal and glial loss after spinal cord contusion. Exp Neurol 168:273-282.
    • (2001) Exp Neurol , vol.168 , pp. 273-282
    • Grossman, S.D.1    Rosenberg, L.J.2    Wrathall, J.R.3
  • 18
    • 0034119666 scopus 로고    scopus 로고
    • Sequential mRNA expression for immediate early genes, cytokines, and neurotrophins in spinal cord injury
    • Hayashi M, Ueyama T, Nemoto K, Tamaki T, and Senba E (2000) Sequential mRNA expression for immediate early genes, cytokines, and neurotrophins in spinal cord injury. J Neurotrauma 17:203-218.
    • (2000) J Neurotrauma , vol.17 , pp. 203-218
    • Hayashi, M.1    Ueyama, T.2    Nemoto, K.3    Tamaki, T.4    Senba, E.5
  • 19
    • 0003633755 scopus 로고    scopus 로고
    • Institute of Laboratory Animal Resources , 7th ed. Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council, Washington DC
    • Institute of Laboratory Animal Resources (1996) Guide for the Care and Use of Laboratory Animals, 7th ed. Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council, Washington DC.
    • (1996) Guide for the Care and Use of Laboratory Animals
  • 20
    • 3342967871 scopus 로고    scopus 로고
    • Pathophysiology and pharmacologic treatment of acute spinal cord injury
    • Kwon BK, Tetzlaff W, Grauer JN, Beiner J, and Vaccaro AR (2004) Pathophysiology and pharmacologic treatment of acute spinal cord injury. Spine J 4:451-464.
    • (2004) Spine J , vol.4 , pp. 451-464
    • Kwon, B.K.1    Tetzlaff, W.2    Grauer, J.N.3    Beiner, J.4    Vaccaro, A.R.5
  • 21
    • 0034708268 scopus 로고    scopus 로고
    • Combined treatment with alphaMSH and methylprednisolone fails to improve functional recovery after spinal injury in the rat
    • Lankhorst AJ, ter Laak MP, Hamers FP, and Gispen WH (2000) Combined treatment with alphaMSH and methylprednisolone fails to improve functional recovery after spinal injury in the rat. Brain Res 859:334-340.
    • (2000) Brain Res , vol.859 , pp. 334-340
    • Lankhorst, A.J.1    ter Laak, M.P.2    Hamers, F.P.3    Gispen, W.H.4
  • 22
    • 0037377555 scopus 로고    scopus 로고
    • Amelioration of ischemia-reperfusion injury with cyclic peptide blockade of ICAM-1
    • Merchant SH, Gurule DM, and Larson RS (2003) Amelioration of ischemia-reperfusion injury with cyclic peptide blockade of ICAM-1. Am J Physiol 284:1260-1268.
    • (2003) Am J Physiol , vol.284 , pp. 1260-1268
    • Merchant, S.H.1    Gurule, D.M.2    Larson, R.S.3
  • 24
    • 0030221758 scopus 로고    scopus 로고
    • Cytokines in inflammatory brain lesions: Helpful and harmful
    • Merrill JE and Benveniste EN (1996) Cytokines in inflammatory brain lesions: helpful and harmful. Trends Neurosci 19:331-338.
    • (1996) Trends Neurosci , vol.19 , pp. 331-338
    • Merrill, J.E.1    Benveniste, E.N.2
  • 25
    • 0035191972 scopus 로고    scopus 로고
    • Neutralization of Gro alpha and macrophage inflammatory protein-2 attenuates renal ischemia/reperfusion injury
    • Miura M, Fu X, Zhang QW, Remick DG, and Fairchild RL (2001) Neutralization of Gro alpha and macrophage inflammatory protein-2 attenuates renal ischemia/reperfusion injury. Am J Pathol 159:2137-2145.
    • (2001) Am J Pathol , vol.159 , pp. 2137-2145
    • Miura, M.1    Fu, X.2    Zhang, Q.W.3    Remick, D.G.4    Fairchild, R.L.5
  • 26
    • 8444248263 scopus 로고    scopus 로고
    • Suppression of GDNF production by MPSS treatment following spinal cord injury in the rat
    • Nakashima S, Matsuyama Y, Yu Y, Kiuchi K, and Ishiguro N (2004) Suppression of GDNF production by MPSS treatment following spinal cord injury in the rat. Neuroreport 15:2337-2340.
    • (2004) Neuroreport , vol.15 , pp. 2337-2340
    • Nakashima, S.1    Matsuyama, Y.2    Yu, Y.3    Kiuchi, K.4    Ishiguro, N.5
  • 28
    • 0032814562 scopus 로고    scopus 로고
    • Neuroglial activation repertoire in the injured brain: Graded response, molecular mechanisms and cues to physiological function
    • Raivich G, Bohatschek M, Kloss CU, Werner A, Jones LL, and Kreutzberg GW (1999) Neuroglial activation repertoire in the injured brain: graded response, molecular mechanisms and cues to physiological function. Brain Res Rev 30:77-105.
    • (1999) Brain Res Rev , vol.30 , pp. 77-105
    • Raivich, G.1    Bohatschek, M.2    Kloss, C.U.3    Werner, A.4    Jones, L.L.5    Kreutzberg, G.W.6
  • 29
    • 0022345349 scopus 로고
    • Glucocorticoids potentiate ischemic injury to neurons: Therapeutic implications
    • Sapolsky RM and Pulsinelli WA (1985) Glucocorticoids potentiate ischemic injury to neurons: therapeutic implications. Science 229:1397- 1400.
    • (1985) Science , vol.229 , pp. 1397-1400
    • Sapolsky, R.M.1    Pulsinelli, W.A.2
  • 31
    • 0023680625 scopus 로고
    • Involvement of tumor necrosis factor in endotoxin-triggered neutrophil adherence to sinusoidal endothelial cells of mouse liver and its modulation in acute phase
    • Schlayer HJ, Laaff H, Peters T, Woort-Menker M, Estler HC, Karck U, Schaefer HE, and Decker K (1988) Involvement of tumor necrosis factor in endotoxin-triggered neutrophil adherence to sinusoidal endothelial cells of mouse liver and its modulation in acute phase. J Hepatol 7:239-249.
    • (1988) J Hepatol , vol.7 , pp. 239-249
    • Schlayer, H.J.1    Laaff, H.2    Peters, T.3    Woort-Menker, M.4    Estler, H.C.5    Karck, U.6    Schaefer, H.E.7    Decker, K.8
  • 32
    • 0032821690 scopus 로고    scopus 로고
    • Acute inflammatory responses to mechanical lesions in CNS: Differences between brain and spinal cord
    • Schnell L, Fearn S, Klassen H, Schwab ME, and Perry VH (1999) Acute inflammatory responses to mechanical lesions in CNS: differences between brain and spinal cord. Eur J Neurosci 11:3648-3658.
    • (1999) Eur J Neurosci , vol.11 , pp. 3648-3658
    • Schnell, L.1    Fearn, S.2    Klassen, H.3    Schwab, M.E.4    Perry, V.H.5
  • 33
    • 0034024692 scopus 로고    scopus 로고
    • High dose methylprednisolone in the management of acute spinal cord injury - a systematic review from a clinical perspective
    • Short DJ, El Masry WS, and Jones PW (2000) High dose methylprednisolone in the management of acute spinal cord injury - a systematic review from a clinical perspective. Spinal Cord 38:273-286.
    • (2000) Spinal Cord , vol.38 , pp. 273-286
    • Short, D.J.1    El Masry, W.S.2    Jones, P.W.3
  • 34
    • 4644280675 scopus 로고    scopus 로고
    • Repertaxin, a novel inhibitor of rat CXCR2 function, inhibits inflammatory responses that follow intestinal ischemia and reperfusion injury
    • Souza DG, Bertini R, Vieira A, Cunha FQ, Poole S, Allegretti M, Colotta F, and Teixeira MM (2004) Repertaxin, a novel inhibitor of rat CXCR2 function, inhibits inflammatory responses that follow intestinal ischemia and reperfusion injury. Br J Pharmacol 143:132-142.
    • (2004) Br J Pharmacol , vol.143 , pp. 132-142
    • Souza, D.G.1    Bertini, R.2    Vieira, A.3    Cunha, F.Q.4    Poole, S.5    Allegretti, M.6    Colotta, F.7    Teixeira, M.M.8
  • 35
    • 0035167833 scopus 로고    scopus 로고
    • Effects of inhibition of PDE4 and TNF-alpha on local and remote injuries following ischaemia and reperfusion injury
    • Souza DG, Cassali GD, Poole S, and Teixeira MM (2001) Effects of inhibition of PDE4 and TNF-alpha on local and remote injuries following ischaemia and reperfusion injury. Br J Pharmacol 134:985-994.
    • (2001) Br J Pharmacol , vol.134 , pp. 985-994
    • Souza, D.G.1    Cassali, G.D.2    Poole, S.3    Teixeira, M.M.4
  • 36
    • 0036098612 scopus 로고    scopus 로고
    • Increased mortality and inflammation in tumor necrosis factor-stimulate gene-14 transgenic mice after ischemia and reperfusion injury
    • Souza DG, Soares AC, Pinho V, Torloni H, Reis LF, Teixeira MM, and Dias AA (2002) Increased mortality and inflammation in tumor necrosis factor-stimulate gene-14 transgenic mice after ischemia and reperfusion injury. Am J Pathol 160:1755-1765.
    • (2002) Am J Pathol , vol.160 , pp. 1755-1765
    • Souza, D.G.1    Soares, A.C.2    Pinho, V.3    Torloni, H.4    Reis, L.F.5    Teixeira, M.M.6    Dias, A.A.7
  • 37
  • 38
    • 0037432615 scopus 로고    scopus 로고
    • Multiple pathways of peroxynitrite cytotoxicity
    • Szabo C (2003). Multiple pathways of peroxynitrite cytotoxicity. Toxicol Lett 140-141:105-112.
    • (2003) Toxicol Lett , vol.140-141 , pp. 105-112
    • Szabo, C.1
  • 40
    • 0030634193 scopus 로고    scopus 로고
    • Pharmacologic approaches to reperfusion injury
    • Willerson JT (1997) Pharmacologic approaches to reperfusion injury. Adv Pharmacol 39:291-312.
    • (1997) Adv Pharmacol , vol.39 , pp. 291-312
    • Willerson, J.T.1
  • 41
    • 13844251822 scopus 로고    scopus 로고
    • Erythropoietin treatment improves neurological functional recovery in EAE mice
    • Zhang J, Li Y, Cui Y, Chen J, Lu M, Elias SB, and Chopp M (2005) Erythropoietin treatment improves neurological functional recovery in EAE mice. Brain Res 1034:34-39.
    • (2005) Brain Res , vol.1034 , pp. 34-39
    • Zhang, J.1    Li, Y.2    Cui, Y.3    Chen, J.4    Lu, M.5    Elias, S.B.6    Chopp, M.7


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