Treating myocardial ischemia-reperfusion injury by targeting endothelial cell transcription

Annals of Thoracic Surgery

Volumn 68, Issue 5, 1999, Pages 1949-1953

  Boyle Jr , Edward M ^a   Canty Jr , Timothy G ^a   Morgan, Elizabeth N ^a   Yun, Wang ^a   Pohlman, Timothy H ^a   Verrier, Edward D ^a  

^a Divisions of Cardiothoracic Surgery   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR;

AORTA CLAMPING; CONFERENCE PAPER; DISEASE SEVERITY; GENE TARGETING; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART SURGERY; HUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; TRANSCRIPTION REGULATION;

ANIMALS; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION; HUMANS; MYOCARDIAL REPERFUSION INJURY; NF-KAPPA B; OXIDATIVE STRESS; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; THROMBOMODULIN; TRANSCRIPTION, GENETIC;

EID: 0344614533     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-4975(99)01033-4     Document Type: Conference Paper

References (26)

1. Hill C.S., Treisman R. Transcriptional regulation by extracellular signals mechanisms and specificity . Cell. 80:1995;199-221.
2. Boyle E.M. Jr, Pohlman T.H., Cornejo C.J., Verrier E.D. Endothelial cell injury in cardiovascular surgery ischemia-reperfusion . Ann Thorac Surg. 62:1996;1868-1875.
3. Esmon C.T. The regulation of natural anticoagulant pathways. Science. 235:1987;1348-1352.
4. Sellke F.W., Boyle E.M. Jr, Verrier E.D. Endothelial cell injury in cardiovascular surgery the pathophysiology of vasomotor dysfunction . Ann Thorac Surg. 62:1996;1222-1228.
5. Pinsky D.J., Yan S.F., Lawson C., et al. Hypoxia and modification of the endothelium implications for regulation of vascular homeostatic properties . Semin Cell Biol. 6:1995;283-294.
6. Winn R.K., Ramamoorthy C., Vedder N.B., et al. Leukocyte-endothelial cell interactions in ischemia-reperfusion injury. Ann NY Acad Sci. 832:1997;311-321.
7. Weiss S.J. Tissue destruction by neutrophils. N Engl J Med. 320:1989;365-376.
8. Collins T., Read M.A., Neish A.S., et al. Transcriptional regulation of endothelial cell adhesion molecules NF-kappa B and cytokine inducible enhancers . FASEB J. 9:1995;899-909.
9. Baeuerle P.A., Henkel T. Function and activation of NF-kappa B in the immune system. Ann Rev Immunol. 12:1994;141-179.
10. Collins T., Read M.A., Neish A.S., et al. Transcriptional regulation of endothelial cell adhesion molecules NF-kappa B and cytokine-inducible enhancers . FASEB J. 9:1995;899-909.
11. Finco T.S., Baldwin A.S. Mechanistic aspects of NF kappa B regulation the emerging role of phosphorylation and proteolysis . Immunity. 3:1995;263-272.
12. Verma I.M., Stevenson J.K., Schwarz E.M., et al. Rel/NF-kappa B/I kappa B family intimate tales of association and dissociation . Genes Dev. 9:1995;2723-2735.
13. Sun S.C., Ganachi P.A., Ballard D.W., Greene W.C. NF kappa B controls expression of inhibitor I kappa B alpha evidence for an inducible autoregulatory pathway . Science. 295:1993;1912-1915.
14. Read M.A., Whitley M.Z., Williams A.J., Collins T. NF-kappa B and I kappa B alpha an inducible regulatory system in endothelial cells . J Exp Med. 179:1994;503-512.
15. Read M.A., Neish A.S., Gerritsen M.E., T C. Postinduction trascriptional repression of E-selectin and vascular cell adhesion molecule-1. J Immunol. 157:1996;3472-3479.
16. Goodman D.J., von Albertini A.M., McShea A., Wrighton C.J., Bach F.H. Adenoviral mediated overexpression of I (kappa) B (alpha) in endothelial cells inhibits natural killer cell mediated endothelial cell expression. Transplantation. 62:1996;967-972.
17. Golino P., Ragni M., Cirillo P., et al. Effects of tissue factor induced by oxygen free radicals on coronary flow during reperfusion. Nat Med. 2:1996;35-40.
18. Broze G.J. Jr, Likert K., Higuchi D. Inhibition of factor VIIa/tissue factor by antithrombin III and tissue factor pathway inhibitor. [letter] Blood. 82:1993;1679-1681.
19. Imbert V., Rupec R.A., Livolsi A., et al. Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha. Cell. 86:1996;787-798.
20. Marui N., Offermann M.K., Swerlick R., et al. Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells. J Clin Invest. 92:1993;1866-1874.
21. Haddix T.L., Pohlman T.H., Noel R.F., et al. Hypothermia inhibits human E-selectin transcription. J Surg Res. 64:1996;176-183.
22. Chen C.C., Rosenbloom C.L., Anderson D.C., Manning A.M. Selective inhibition of E-selectin, vascular cell adhesion molecule-1, and intercellular adhesion molecule-1 expression by inhibitors of I kappa B-alpha phosphorylation. J Immunol. 155:1995;3538-3545.
23. Ollivier V., Parry G.C.N., Cobb R.R., et al. Elevated cyclic AMP inhibits NF-kappaB-mediated transcription in human monocytic cells and endothelial cells. J Biol Chem. 271:1996;20828-20835.
24. Anrather J., Csizmadia V., Brostjan C., et al. Inhibition of bovine endothelial cell activation in vitro by regulated expression of a transdominant inhibitor of NF-kappa B. J Clin Invest. 99:1997;763-772.
25. Morishita R., Sugimoto T., Aoki M., et al. In vivo transfection of cis element "decoy" against nuclear factor-kappaB binding site prevents myocardial infarction. Nature Med. 3:1997;894-899.
26. Sharar S.R., Winn R.K., Murry C.E., et al. A CD18 monoclonal antibody increases the incidence and severity of subcutaneous abscess formation after high-dose Staphylococcus aureus injection in rabbits. Surgery. 110:1991;213-220.