Differential effects of σ1 receptor blockade on self-administration and conditioned reinstatement motivated by cocaine vs natural reward

Neuropsychopharmacology

Volumn 32, Issue 9, 2007, Pages 1967-1973

  Martin Fardon, Rémi ^a   Maurice, Tangui ^b   Aujla, Harinder ^a   Bowen, Wayne D ^c   Weiss, Friedbert ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b University of Montpellier   (France)

^c BROWN UNIVERSITY   (United States)

Author keywords

Addiction; BD1047; Drug cues; Drug seeking behavior; Relapse; Self administration

Indexed keywords

COCAINE; N [2 (2,3 DICHLOROPHENYL)ETHYL] 2 DIMETHYLAMINO N METHYLETHYLAMINE; N [2 (3,4 DICHLOROPHENYL)ETHYL] N METHYL 2 (DIMETHYLAMINO)ETHYLAMINE; SIGMA 1 OPIATE RECEPTOR; SIGMA 1 OPIATE RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG; DOPAMINE UPTAKE INHIBITOR; ETHYLENEDIAMINE DERIVATIVE; N [2 (3,4 DICHLOROPHENYL)ETHYL] 2 DIMETHYLAMINO N METHYLETHYLAMINE; SIGMA OPIATE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; APPETITE; ARTICLE; COCAINE DEPENDENCE; COGNITION; CONDITIONING; CONTROLLED STUDY; DEPRESSION; DISCRIMINATIVE STIMULUS; DRUG POTENCY; DRUG SELECTIVITY; MALE; MILK; MOTIVATION; NONHUMAN; PLACE PREFERENCE; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; REINFORCEMENT; RELAPSE; REWARD; STRESS; WITHDRAWAL SYNDROME; ANALYSIS OF VARIANCE; ANIMAL; ANIMAL BEHAVIOR; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; DRUG SELF ADMINISTRATION; FOOD PREFERENCE; INSTRUMENTAL CONDITIONING; PHYSIOLOGY; WISTAR RAT;

ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; COCAINE; CONDITIONING, OPERANT; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHYLENEDIAMINES; FOOD PREFERENCES; MALE; MILK; RATS; RATS, WISTAR; RECEPTORS, SIGMA; REWARD; SELF ADMINISTRATION;

EID: 34547898058     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1301323     Document Type: Article

References (45)

1. Alonso G, Phan V, Guillemain I, Saunier M, Legrand A, Anoal M et al (2000). Immunocytochemical localization of the sigma(1) receptor in the adult rat central nervous system. Neuroscience 97: 155-170.
2. Baptista MA, Martin-Fardon R, Weiss F (2004). Preferential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on conditioned reinstatement versus primary reinforcement: comparison between cocaine and a potent conventional reinforcer. J Neurosci 24: 4723-4727.
3. Buydens-Branchey L, Branchey M (2004). Cocaine addicts with conduct disorder are typified by decreased cortisol responsivity and high plasma levels of DHEA-S. Neuropsychobiology 50: 161-166.
4. Buydens-Branchey L, Branchey M, Hudson J, Dorota Majewska M (2002). Perturbations of plasma cortisol and DHEA-S following discontinuation of cocaine use in cocaine addicts. Psychoneuroendocrinology 27: 83-97.
5. Caine SB, Lintz R, Koob GF (1993). Intravenous drug self-administration techniques in animals. In: Sahgal A (ed). Behavioral Neuroscience: A Practical Approach, Vol. 2. University Press: Oxford. pp 117-143.
6. Daniels A, Ayala E, Chen W, Coop A, Matsumoto RR (2006). N-[2-(m-methoxyphenyl)ethyl]-N-ethyl-2-(1-pyrrolidinyl) ethylamine (UMB 116) is a novel antagonist for cocaine-induced effects. Eur J Pharmacol, print copy in press (originally published online April 5, 2006, at www.sciencedirect.com).
7. Doron R, Fridman L, Gispan-Herman I, Maayan R, Weizman A, Yadid G (2006). DHEA, a neurosteroid, decreases cocaine self-administration and reinstatement of cocaine-seeking behavior in rats. Neuropsychopharmacology 31: 2231-2236.
8. Fuchs RA, Evans KA, Ledford CC, Parker MP, Case JM, Mehta RH et al (2005). The role of the dorsomedial prefrontal cortex, basolateral amygdala, and dorsal hippocampus in contextual reinstatement of cocaine seeking in rats. Neuropsychopharmacology 30: 296-309.
9. Grimm JW, Shaham Y, Hope BT (2002). Effect of cocaine and sucrose withdrawal period on extinction behavior, cue-induced reinstatement, and protein levels of the dopamine transporter and tyrosine hydroxylase in limbic and cortical areas in rats. Behav Pharmacol 13: 379-388.
10. Hayashi T, Su TP (2001). Regulating ankyrin dynamics: roles of sigma-1 receptors. Proc Natl Acad Sci USA 98: 491-496.
11. Hayashi T, Su TP (2003a). Intracellular dynamics of sigma-1 receptors (sigma(1) binding sites) in NG108-15 cells. J Pharmacol Exp Ther 306: 726-733.
12. Hayashi T, Su TP (2003b). Sigma-1 receptors (sigma(1) binding sites) form raft-like microdomains and target lipid droplets on the endoplasmic reticulum: roles in endoplasmic reticulum lipid compartmentalization and export. J Pharmacol Exp Ther 306: 718-725.
13. Hemby SE, Co C, Koves TR, Smith JE, Dworkin SI (1997). Differences in extracellular dopamine concentrations in the nucleus accumbens during response-dependent and response-independent cocaine administration in the rat. Psychopharmacology 133: 7-16.
14. Holland PC, Bouton ME (1999). Hippocampus and context in classical conditioning. Curr Opin Neurobiol 9: 195-202.
15. Jacobs EH, Smit AB, de Vries TJ, Schoffelmeer AN (2003). Neuroadaptive effects of active versus passive drug administration in addiction research. Trends Pharmacol Sci 24: 566-573.
16. Kalivas PW, McFarland K (2003). Brain circuitry and the reinstatement of cocaine-seeking behavior. Psychopharmacology (Berl) 168: 44-56.
17. Katz JL, Libby TA, Kopajtic T, Husbands SM, Newman AH (2003). Behavioral effects of rimcazole analogues alone and in combination with cocaine. Eur J Pharmacol 468: 109-119.
18. Liu Y, Chen GD, Lerner MR, Brackett DJ, Matsumoto RR (2005). Cocaine up-regulates Fra-2 and sigma-1 receptor gene and protein expression in brain regions involved in addiction and reward. J Pharmacol Exp Ther 314: 770-779.
19. Maayan R, Lotan S, Doron R, Shabat-Simon M, Gispan-Herman I, Weizman A et al (2006). Dehydroepiandrosterone (DHEA) attenuates cocaine-seeking behavior in the self-administration model in rats. Eur Neuropsychopharmacol 16: 329-339.
20. Matsumoto RR, Bowen WD, Tom MA, Vo VN, Truong DD, De Costa BR (1995). Characterization of two novel sigma receptor ligands: antidystonic effects in rats suggest sigma receptor antagonism. Eur J Pharmacol 280: 301-310.
21. Matsumoto RR, McCracken KA, Pouw B, Miller J, Bowen WD, Williams W et al (2001). N-alkyl substituted analogs of the sigma receptor ligand BD1008 and traditional sigma receptor ligands affect cocaine-induced convulsions and lethality in mice. Eur J Pharmacol 411: 261-273.
22. Maurice T (2004). Neurosteroids and sigma1 receptors, biochemical and behavioral relevance. Pharmacopsychiatry 37(Suppl 3): S171-S182.
23. Maurice T, Martin-Fardon R, Romieu P, Matsumoto RR (2002). Sigma(1) (sigma(1)) receptor antagonists represent a new strategy against cocaine addiction and toxicity. Neurosci Biobehav Rev 26: 499-527.
24. Maurice T, Phan VL, Privat A (2001). The anti-amnesic effects of sigma1 (sigma1) receptor agonists confirmed by in vivo antisense strategy in the mouse. Brain Res 898: 113-121.
25. McCracken KA, Bowen WD, de Costa BR, Matsumoto RR (1999a). Two novel sigma receptor ligands, BD1047 and LR172, attenuate cocaine- induced toxicity and locomotor activity. Eur J Pharmacol 370: 225-232.
26. McCracken KA, Bowen WD, Matsumoto RR (1999b). Novel sigma receptor ligands attenuate the locomotor stimulatory effects of cocaine. Eur J Pharmacol 365: 35-38.
27. McFarland K, Lapish CC, Kalivas PW (2003). Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug-seeking behavior. J Neurosci 23: 3531-3537.
28. Menkel M, Terry P, Pontecorvo M, Katz JL, Witkin JM (1991). Selective sigma ligands block stimulant effects of cocaine. Eur J Pharmacol 201: 251-252.
29. 1 protein as a target for the non-genomic effects of neuro(active)steroids: molecular, physiological, and behavioral aspects. J Pharmacol Sci 100: 93-118.
30. Monnet FP, Morin-Surun MP, Leger J, Combettes L (2003). Protein kinase C-dependent potentiation of intracellular calcium influx by sigma1 receptor agonists in rat hippocampal neurons. J Pharmacol Exp Ther 307: 705-712.
31. O'Brien CP, Childress AR, Ehrman R, Robbins SJ (1998). Conditioning factors in drug abuse: can they explain compulsion? J Psychopharmacol 12: 15-22.
32. Romieu P, Lucas M, Maurice T (2006). Sigma(1) receptor ligands and related neuroactive steroids interfere with the cocaine-induced state of memory. Neuropsychopharmacology 31: 1431-1443.
33. Romieu P, Martin-Fardon R, Bowen WD, Maurice T (2003). Sigma 1 receptor-related neuroactive steroids modulate cocaine-induced reward. J Neurosci 23: 3572-3576.
34. Romieu P, Martin-Fardon R, Maurice T (2000). Involvement of the sigma1 receptor in the cocaine-induced conditioned place preference. Neuroreport 11: 2885-2888.
35. Romieu P, Meunier J, Garcia D, Zozime N, Martin-Fardon R, Bowen WD et al (2004). The sigma1 (sigma1) receptor activation is a key step for the reactivation of cocaine conditioned place preference by drug priming. Psychopharmacology (Berl) 175: 154-162.
36. Romieu P, Phan VL, Martin-Fardon R, Maurice T (2002). Involvement of the sigma(1) receptor in cocaine-induced conditioned place preference: possible dependence on dopamine uptake blockade. Neuropsychopharmacology 26: 444-455.
37. See RE (2002). Neural substrates of conditioned-cued relapse to drug-seeking behavior. Pharmacol Biochem Behav 71: 517-529.
38. Shaham Y, Shalev U, Lu L, De Wit H, Stewart J (2003). The reinstatement model of drug relapse: history, methodology and major findings. Psychopharmacology (Berl) 168: 3-20.
39. Stefanski R, Justinova Z, Hayashi T, Takebayashi M, Goldberg SR, Su TP (2004). Sigma1 receptor upregulation after chronic methamphetamine self-administration in rats: a study with yoked controls. Psychopharmacology (Berl) 175: 68-75.
40. Su TP, Hayashi T (2003). Understanding the molecular mechanism of sigma-1 receptors: towards a hypothesis that sigma-1 receptors are intracellular amplifiers for signal transduction. Curr Med Chem 10: 2073-2080.
41. Ujike H, Kuroda S, Otsuki S (1996). sigma Receptor antagonists block the development of sensitization to cocaine. Eur J Pharmacol 296: 123-128.
42. Urani A, Roman FJ, Phan VL, Su TP, Maurice T (2001). The antidepressant-like effect induced by sigma(1)-receptor agonists and neuroactive steroids in mice submitted to the forced swimming test. J Pharmacol Exp Ther 298: 1269-1279.
43. Weiss F (2005). Neurobiology of craving, conditioned reward and relapse. Curr Opin Pharmacol 5: 9-19.
44. Weiss F, Maldonado-Vlaar CS, Parsons LH, Kerr TM, Smith DL, Ben-Shahar O (2000). Control of cocaine-seeking behavior by drug-associated stimuli in rats: effects on recovery of extinguished operant responding and extracellular dopamine levels in amygdala and nucleus accumbens. Proc Natl Acad Sci USA 97: 4321-4326.
45. Wise RA (2000). Addiction becomes a brain disease. Neuron 26: 27-33.