Understanding the molecular mechanism of sigma-1 receptors: Towards a hypothesis that sigma-1 receptors are intracellular amplifiers for signal transduction

Current Medicinal Chemistry

Volumn 10, Issue 20, 2003, Pages 2073-2080

  Su, Tsung Ping ^a   Hayashi, Teruo ^a  

^a Intramural Research Program   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [1 (2 BENZO[B]THIENYL)CYCLOHEXYL]PIPERIDINE; 1 PHENYLCYCLOHEXANECARBOXYLIC ACID 2 MORPHOLINOETHYL ESTER; ADAPTOR PROTEIN; ALPHA (4 FLUOROPHENYL) 4 (5 FLUORO 2 PYRIMIDINYL) 1 PIPERAZINEBUTANOL; AMINO ACID; BENZOMORPHAN; COCAINE; CYTOSKELETON PROTEIN; DIZOCILPINE; HALOPERIDOL; IMIPRAMINE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; MECAMYLAMINE; METABOTROPIC RECEPTOR; METHAMPHETAMINE; MONOAMINE OXIDASE INHIBITOR; N ALLYLNORMETAZOCINE; NERVE GROWTH FACTOR; NEUROSTEROID; NIMODIPINE; PENTAZOCINE; POTASSIUM CHANNEL; PREGNENOLONE SULFATE; PROGESTERONE; PROTEIN SUBUNIT; RECEPTOR SUBTYPE; SEROTONIN UPTAKE INHIBITOR; SIGMA 1 OPIATE RECEPTOR; SIGMA OPIATE RECEPTOR; SIGMA RECEPTOR LIGAND; UNINDEXED DRUG;

AMINO ACID COMPOSITION; CALCIUM SIGNALING; CENTRAL NERVOUS SYSTEM; DEPRESSION; DOPAMINERGIC SYSTEM; DRUG DESIGN; DRUG MECHANISM; ENDOPLASMIC RETICULUM; GENE AMPLIFICATION; GENE EXPRESSION; HUMAN; HYPOTHESIS; INTRACELLULAR SPACE; LEARNING; MEMORY; MOLECULAR MECHANICS; NERVE SPROUTING; NERVE STIMULATION; NEUROMODULATION; NEUROTRANSMITTER RELEASE; NOCICEPTION; NONHUMAN; PERIPHERAL NERVOUS SYSTEM; PLACE PREFERENCE; REVIEW; SENSITIZATION; SIGNAL TRANSDUCTION;

ANIMALS; HISTORY, 20TH CENTURY; HISTORY, 21ST CENTURY; HUMANS; ION CHANNELS; N-METHYLASPARTATE; RECEPTORS, SIGMA; SIGNAL TRANSDUCTION;

EID: 0141426716     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929867033456783     Document Type: Review

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