-
1
-
-
33746294223
-
-
Braman SS. The global burden of asthma. Chest 2006;130(1Suppl):4S-12S.
-
Braman SS. The global burden of asthma. Chest 2006;130(1Suppl):4S-12S.
-
-
-
-
2
-
-
33646799069
-
Global and regional burden of disease and risk factors, 2001: Systematic analysis of population health data
-
Lopez AD, Mathers CD, Ezzati M, et al. Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet 2006;367:1747-57.
-
(2006)
Lancet
, vol.367
, pp. 1747-1757
-
-
Lopez, A.D.1
Mathers, C.D.2
Ezzati, M.3
-
3
-
-
4444272836
-
Dissociation of lung function and airway inflammation in chronic obstructive pulmonary disease
-
Lapperre TS, Snoeck-Stroband JB, Gosman MM, et al. Dissociation of lung function and airway inflammation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2004;170:499-504.
-
(2004)
Am J Respir Crit Care Med
, vol.170
, pp. 499-504
-
-
Lapperre, T.S.1
Snoeck-Stroband, J.B.2
Gosman, M.M.3
-
4
-
-
0034012913
-
Association of sputum parameters with clinical and functional measurements in asthma
-
Rosi E, Scano G. Association of sputum parameters with clinical and functional measurements in asthma. Thorax 2000;55:235-8.
-
(2000)
Thorax
, vol.55
, pp. 235-238
-
-
Rosi, E.1
Scano, G.2
-
5
-
-
0026541094
-
Use of induced sputum cell counts to investigate airway inflammation in asthma
-
Pin I, Gibson PG, Kolendowicz R, et al. Use of induced sputum cell counts to investigate airway inflammation in asthma. Thorax 1992;47:25-9.
-
(1992)
Thorax
, vol.47
, pp. 25-29
-
-
Pin, I.1
Gibson, P.G.2
Kolendowicz, R.3
-
7
-
-
0036725783
-
Methods of sputum processing for cell counts, immunocytochemistry and in situ hybridisation
-
s
-
Efthimiadis A, Spanevello A, Hamid Q, et al. Methods of sputum processing for cell counts, immunocytochemistry and in situ hybridisation. Eur Respir J Suppl 2002;37:19s-23s.
-
(2002)
Eur Respir J Suppl
, vol.37
-
-
Efthimiadis, A.1
Spanevello, A.2
Hamid, Q.3
-
8
-
-
0025650904
-
Long-term effects of budesonide on airway responsiveness and clinical asthma severity in inhaled steroid-dependent asthmatics
-
Juniper EF, Kline PA, Vanzieleghem MA, et al. Long-term effects of budesonide on airway responsiveness and clinical asthma severity in inhaled steroid-dependent asthmatics. Eur Respir J 1990;3:1122-7.
-
(1990)
Eur Respir J
, vol.3
, pp. 1122-1127
-
-
Juniper, E.F.1
Kline, P.A.2
Vanzieleghem, M.A.3
-
9
-
-
0025036349
-
Effect of long-term treatment with an inhaled corticosteroid (budesonide) on airway hyperresponsiveness and clinical asthma in nonsteroid-dependent asthmatics
-
Juniper EF, Kline PA, Vanzieleghem MA, et al. Effect of long-term treatment with an inhaled corticosteroid (budesonide) on airway hyperresponsiveness and clinical asthma in nonsteroid-dependent asthmatics. Am Rev Respir Dis 1990;142:832-6.
-
(1990)
Am Rev Respir Dis
, vol.142
, pp. 832-836
-
-
Juniper, E.F.1
Kline, P.A.2
Vanzieleghem, M.A.3
-
10
-
-
0026010030
-
Comparison of a beta 2-agonist, terbutaline, with an inhaled corticosteroid, budesonide, in newly detected asthma
-
Haahtela T, Jarvinen M, Kava T, et al. Comparison of a beta 2-agonist, terbutaline, with an inhaled corticosteroid, budesonide, in newly detected asthma. N Engl J Med 1991;325:388-92.
-
(1991)
N Engl J Med
, vol.325
, pp. 388-392
-
-
Haahtela, T.1
Jarvinen, M.2
Kava, T.3
-
12
-
-
0036063208
-
The effects of inhaled corticosteroids in chronic obstructive pulmonary disease: A systematic review of randomized placebo-controlled trials
-
Alsaeedi A, Sin DD, McAlister FA. The effects of inhaled corticosteroids in chronic obstructive pulmonary disease: a systematic review of randomized placebo-controlled trials. Am J Med 2002;113:59-65.
-
(2002)
Am J Med
, vol.113
, pp. 59-65
-
-
Alsaeedi, A.1
Sin, D.D.2
McAlister, F.A.3
-
13
-
-
16444362938
-
Inhaled corticosteroids in chronic obstructive pulmonary disease: Is there a clinical benefit?
-
Man SF, Sin DD. Inhaled corticosteroids in chronic obstructive pulmonary disease: is there a clinical benefit? Drugs 2005;65:579-91.
-
(2005)
Drugs
, vol.65
, pp. 579-591
-
-
Man, S.F.1
Sin, D.D.2
-
14
-
-
0036246458
-
The burden of asthma with specific reference to the United States
-
Beasley R. The burden of asthma with specific reference to the United States. J Allergy Clin Immunol 2002;109(5 Suppl):S482-9.
-
(2002)
J Allergy Clin Immunol
, vol.109
, Issue.5 SUPPL.
-
-
Beasley, R.1
-
15
-
-
33646593833
-
Oral and inhaled corticosteroids and adrenal insufficiency: A case-control study
-
Mortimer KJ, Tata LJ, Smith CJ, et al. Oral and inhaled corticosteroids and adrenal insufficiency: a case-control study. Thorax 2006;61:405-8.
-
(2006)
Thorax
, vol.61
, pp. 405-408
-
-
Mortimer, K.J.1
Tata, L.J.2
Smith, C.J.3
-
17
-
-
0035987316
-
Accuracy of eosinophils and eosinophil cationic protein to predict steroid improvement in asthma
-
Meijer RJ, Postma DS, Kauffman HF, et al. Accuracy of eosinophils and eosinophil cationic protein to predict steroid improvement in asthma. Clin Exp Allergy 2002;32:1096-103.
-
(2002)
Clin Exp Allergy
, vol.32
, pp. 1096-1103
-
-
Meijer, R.J.1
Postma, D.S.2
Kauffman, H.F.3
-
19
-
-
0034057829
-
Non-invasive markers of airway inflammation as predictors of oral steroid responsiveness in asthma
-
Little SA, Chalmers GW, MacLeod KJ, et al. Non-invasive markers of airway inflammation as predictors of oral steroid responsiveness in asthma. Thorax 2000;55:232-4.
-
(2000)
Thorax
, vol.55
, pp. 232-234
-
-
Little, S.A.1
Chalmers, G.W.2
MacLeod, K.J.3
-
20
-
-
4444221246
-
Refractory eosinophilic airway inflammation in severe asthma: Effect of parenteral corticosteroids
-
ten Brinke A, Zwinderman AH, Sterk PJ, et al. "Refractory" eosinophilic airway inflammation in severe asthma: effect of parenteral corticosteroids. Am J Respir Crit Care Med 2004;170:601-5.
-
(2004)
Am J Respir Crit Care Med
, vol.170
, pp. 601-605
-
-
ten Brinke, A.1
Zwinderman, A.H.2
Sterk, P.J.3
-
21
-
-
0031731419
-
Sputum eosinophilia predicts benefit from prednisone in smokers with chronic obstructive bronchitis
-
Pizzichini E, Pizzichini MM, Gibson P, et al. Sputum eosinophilia predicts benefit from prednisone in smokers with chronic obstructive bronchitis. Am J Respir Crit Care Med 1998;158(5 Pt 1):1511-7.
-
(1998)
Am J Respir Crit Care Med
, vol.158
, Issue.5 PART 1
, pp. 1511-1517
-
-
Pizzichini, E.1
Pizzichini, M.M.2
Gibson, P.3
-
22
-
-
0034727453
-
Sputum eosinophilia and short-term response to prednisolone in chronic obstructive pulmonary disease: A randomised controlled trial
-
Brightling CE, Monteiro W, Ward R, et al. Sputum eosinophilia and short-term response to prednisolone in chronic obstructive pulmonary disease: a randomised controlled trial. Lancet 2000;356:1480-5.
-
(2000)
Lancet
, vol.356
, pp. 1480-1485
-
-
Brightling, C.E.1
Monteiro, W.2
Ward, R.3
-
23
-
-
20144382091
-
Sputum eosinophilia and the short term response to inhaled mometasone in chronic obstructive pulmonary disease
-
Brightling CE, McKenna S, Hargadon B, et al. Sputum eosinophilia and the short term response to inhaled mometasone in chronic obstructive pulmonary disease. Thorax 2005;60:193-8.
-
(2005)
Thorax
, vol.60
, pp. 193-198
-
-
Brightling, C.E.1
McKenna, S.2
Hargadon, B.3
-
24
-
-
33749349350
-
Stable COPD: Predicting benefit from high-dose inhaled corticosteroid treatment
-
Leigh R, Pizzichini MM, Morris MM, et al. Stable COPD: predicting benefit from high-dose inhaled corticosteroid treatment. Eur Respir J 2006;27:964-71.
-
(2006)
Eur Respir J
, vol.27
, pp. 964-971
-
-
Leigh, R.1
Pizzichini, M.M.2
Morris, M.M.3
-
25
-
-
0035131758
-
Predictive markers of asthma exacerbation during stepwise dose reduction of inhaled corticosteroids
-
Leuppi JD, Salome CM, Jenkins CR, et al. Predictive markers of asthma exacerbation during stepwise dose reduction of inhaled corticosteroids. Am J Respir Crit Care Med 2001;163:406-12.
-
(2001)
Am J Respir Crit Care Med
, vol.163
, pp. 406-412
-
-
Leuppi, J.D.1
Salome, C.M.2
Jenkins, C.R.3
-
27
-
-
0032990182
-
Prednisone-dependent asthma: Inflammatory indices in induced sputum
-
Pizzichini MM, Pizzichini E, Clelland L, et al. Prednisone-dependent asthma: inflammatory indices in induced sputum. Eur Respir J 1999;13:15-21.
-
(1999)
Eur Respir J
, vol.13
, pp. 15-21
-
-
Pizzichini, M.M.1
Pizzichini, E.2
Clelland, L.3
-
28
-
-
0037202790
-
Asthma exacerbations and sputum eosinophil counts: A randomised controlled trial
-
Green RH, Brightling CE, McKenna S, et al. Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial. Lancet 2002;360:1715-21.
-
(2002)
Lancet
, vol.360
, pp. 1715-1721
-
-
Green, R.H.1
Brightling, C.E.2
McKenna, S.3
-
29
-
-
33344476409
-
Determining asthma treatment by monitoring sputum cell counts: Effect on exacerbations
-
Jayaram L, Pizzichini MM, Cook RJ, et al. Determining asthma treatment by monitoring sputum cell counts: effect on exacerbations. Eur Respir J 2006;27:483-94.
-
(2006)
Eur Respir J
, vol.27
, pp. 483-494
-
-
Jayaram, L.1
Pizzichini, M.M.2
Cook, R.J.3
-
30
-
-
33646787430
-
Strategy aimed at reduction of sputum eosinophils decreases exacerbation rate in patients with asthma
-
Chlumsky J, Striz I, Terl M, Vondracek J. Strategy aimed at reduction of sputum eosinophils decreases exacerbation rate in patients with asthma. J Int Med Res 2006;34:129-39.
-
(2006)
J Int Med Res
, vol.34
, pp. 129-139
-
-
Chlumsky, J.1
Striz, I.2
Terl, M.3
Vondracek, J.4
-
31
-
-
0030900606
-
Inflammation in bronchial biopsies of subjects with chronic bronchitis: Inverse relationship of CD8+ T lymphocytes with FEV1
-
O'Shaughnessy TC, Ansari TW, Barnes NC, Jeffery PK. Inflammation in bronchial biopsies of subjects with chronic bronchitis: inverse relationship of CD8+ T lymphocytes with FEV1. Am J Respir Crit Care Med 1997;155:852-7.
-
(1997)
Am J Respir Crit Care Med
, vol.155
, pp. 852-857
-
-
O'Shaughnessy, T.C.1
Ansari, T.W.2
Barnes, N.C.3
Jeffery, P.K.4
-
32
-
-
0032014542
-
CD8+ T-lymphocytes in peripheral airways of smokers with chronic obstructive pulmonary disease
-
Saetta M, Di Stefano A, Turato G, et al. CD8+ T-lymphocytes in peripheral airways of smokers with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1998;157(3 Pt 1):822-6.
-
(1998)
Am J Respir Crit Care Med
, vol.157
, Issue.3 PART 1
, pp. 822-826
-
-
Saetta, M.1
Di Stefano, A.2
Turato, G.3
-
33
-
-
0028027511
-
Airway eosinophilia in chronic bronchitis during exacerbations
-
Saetta M, Di Stefano A, Maestrelli P, et al. Airway eosinophilia in chronic bronchitis during exacerbations. Am J Respir Crit Care Med 1994;150(6 Pt 1):1646-52.
-
(1994)
Am J Respir Crit Care Med
, vol.150
, Issue.6 PART 1
, pp. 1646-1652
-
-
Saetta, M.1
Di Stefano, A.2
Maestrelli, P.3
-
34
-
-
0031841422
-
Inhaled corticosteroids reduce neutrophilic bronchial inflammation in patients with chronic obstructive pulmonary disease
-
Confalonieri M, Mainardi E, Della PR, et al. Inhaled corticosteroids reduce neutrophilic bronchial inflammation in patients with chronic obstructive pulmonary disease. Thorax 1998;53:583-5.
-
(1998)
Thorax
, vol.53
, pp. 583-585
-
-
Confalonieri, M.1
Mainardi, E.2
Della, P.R.3
-
35
-
-
6344267160
-
Relationship between peripheral airway dysfunction, airway obstruction, and neutrophilic inflammation in COPD
-
O'Donnell RA, Peebles C, Ward JA, et al. Relationship between peripheral airway dysfunction, airway obstruction, and neutrophilic inflammation in COPD. Thorax 2004;59:837-42.
-
(2004)
Thorax
, vol.59
, pp. 837-842
-
-
O'Donnell, R.A.1
Peebles, C.2
Ward, J.A.3
-
36
-
-
33845195875
-
Association between markers of emphysema and more severe chronic obstructive pulmonary disease
-
Boschetto P, Quintavalle S, Zeni E, et al. Association between markers of emphysema and more severe chronic obstructive pulmonary disease. Thorax 2006;61:1037-42.
-
(2006)
Thorax
, vol.61
, pp. 1037-1042
-
-
Boschetto, P.1
Quintavalle, S.2
Zeni, E.3
-
37
-
-
33646467684
-
Modulation of eosinophilic airway inflammation in COPD
-
441s
-
Siva R, Green R, Brightling CE, et al. Modulation of eosinophilic airway inflammation in COPD. Eur Respir J 2005;26 Suppl 49:441s.
-
(2005)
Eur Respir J
, vol.26
, Issue.SUPPL. 49
-
-
Siva, R.1
Green, R.2
Brightling, C.E.3
-
38
-
-
0036315787
-
Is there more than one inflammatory phenotype in asthma?
-
O'Donnell RA, Frew AJ. Is there more than one inflammatory phenotype in asthma? Thorax 2002;57:566-8.
-
(2002)
Thorax
, vol.57
, pp. 566-568
-
-
O'Donnell, R.A.1
Frew, A.J.2
-
39
-
-
0036310908
-
Non-eosinophilic asthma: Importance and possible mechanisms
-
Douwes J, Gibson P, Pekkanen J, Pearce N. Non-eosinophilic asthma: importance and possible mechanisms. Thorax 2002;57:643-8.
-
(2002)
Thorax
, vol.57
, pp. 643-648
-
-
Douwes, J.1
Gibson, P.2
Pekkanen, J.3
Pearce, N.4
-
40
-
-
0034942124
-
Heterogeneity of airway inflammation in persistent asthma: Evidence of neutrophilic inflammation and increased sputum interleukin-8
-
Gibson PG, Simpson JL, Saltos N. Heterogeneity of airway inflammation in persistent asthma: evidence of neutrophilic inflammation and increased sputum interleukin-8. Chest 2001;119:1329-36.
-
(2001)
Chest
, vol.119
, pp. 1329-1336
-
-
Gibson, P.G.1
Simpson, J.L.2
Saltos, N.3
-
41
-
-
0032875377
-
Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics
-
Wenzel SE, Schwartz LB, Langmack EL, et al. Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics. Am J Respir Crit Care Med 1999;160:1001-8.
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 1001-1008
-
-
Wenzel, S.E.1
Schwartz, L.B.2
Langmack, E.L.3
-
42
-
-
18744380970
-
Assessment and evaluation of symptomatic steroid-naive asthmatics without sputum eosinophilia and their response to inhaled corticosteroids
-
Godon P, Boulet LP, Malo JL, et al. Assessment and evaluation of symptomatic steroid-naive asthmatics without sputum eosinophilia and their response to inhaled corticosteroids. Eur Respir J 2002;20:1364-9.
-
(2002)
Eur Respir J
, vol.20
, pp. 1364-1369
-
-
Godon, P.1
Boulet, L.P.2
Malo, J.L.3
-
43
-
-
33645117699
-
Clinical and pathological features on non-eosinophilic asthma: A distinct asthma phenotype associated with corticosteroid resistance
-
Berry MA, Morgan A, Green RH, et al. Clinical and pathological features on non-eosinophilic asthma: a distinct asthma phenotype associated with corticosteroid resistance. Thorax 2005;60 Suppl 2:ii4.
-
(2005)
Thorax
, vol.60
, Issue.SUPPL. 2
-
-
Berry, M.A.1
Morgan, A.2
Green, R.H.3
-
44
-
-
0037198418
-
Mast-cell infiltration of airway smooth muscle in asthma
-
Brightling CE, Bradding P, Symon FA, et al. Mast-cell infiltration of airway smooth muscle in asthma. N Engl J Med 2002;346:1699-705.
-
(2002)
N Engl J Med
, vol.346
, pp. 1699-1705
-
-
Brightling, C.E.1
Bradding, P.2
Symon, F.A.3
-
45
-
-
0036187872
-
Influence of cigarette smoking on inhaled corticosteroid treatment in mild asthma
-
Chalmers GW, MacLeod KJ, Little SA, et al. Influence of cigarette smoking on inhaled corticosteroid treatment in mild asthma. Thorax 2002;57:226-30.
-
(2002)
Thorax
, vol.57
, pp. 226-230
-
-
Chalmers, G.W.1
MacLeod, K.J.2
Little, S.A.3
-
46
-
-
33645101537
-
Inflammatory subtypes in asthma: Assessment and identification using induced sputum
-
Simpson JL, Scott R, Boyle MJ, Gibson PG. Inflammatory subtypes in asthma: assessment and identification using induced sputum. Respirology 2006;11:54-61.
-
(2006)
Respirology
, vol.11
, pp. 54-61
-
-
Simpson, J.L.1
Scott, R.2
Boyle, M.J.3
Gibson, P.G.4
-
47
-
-
0028791194
-
Exacerbations of asthma without sputum eosinophilia
-
Turner MO, Hussack P, Sears MR, et al. Exacerbations of asthma without sputum eosinophilia. Thorax 1995;50:1057-61.
-
(1995)
Thorax
, vol.50
, pp. 1057-1061
-
-
Turner, M.O.1
Hussack, P.2
Sears, M.R.3
-
48
-
-
0036191489
-
Occupational asthma due to low molecular weight agents: Eosinophilic and non-eosinophilic variants
-
Anees W, Huggins V, Pavord ID, et al. Occupational asthma due to low molecular weight agents: eosinophilic and non-eosinophilic variants. Thorax 2002;57:231-6.
-
(2002)
Thorax
, vol.57
, pp. 231-236
-
-
Anees, W.1
Huggins, V.2
Pavord, I.D.3
-
50
-
-
10444239309
-
The influence of age on induced sputum differential cell counts in normal subjects
-
Thomas RA, Green RH, Brightling CE, et al. The influence of age on induced sputum differential cell counts in normal subjects. Chest 2004;126:1811-4.
-
(2004)
Chest
, vol.126
, pp. 1811-1814
-
-
Thomas, R.A.1
Green, R.H.2
Brightling, C.E.3
-
51
-
-
0035684297
-
Smoking and airway inflammation in patients with mild asthma
-
Chalmers GW, MacLeod KJ, Thomson L, et al. Smoking and airway inflammation in patients with mild asthma. Chest 2001;120:1917-22.
-
(2001)
Chest
, vol.120
, pp. 1917-1922
-
-
Chalmers, G.W.1
MacLeod, K.J.2
Thomson, L.3
-
52
-
-
0035888715
-
Airway inflammation in children with cystic fibrosis and healthy children assessed by sputum induction
-
Sagel SD, Kapsner R, Osberg I, et al. Airway inflammation in children with cystic fibrosis and healthy children assessed by sputum induction. Am J Respir Crit Care Med 2001;164(8 Pt 1):1425-31.
-
(2001)
Am J Respir Crit Care Med
, vol.164
, Issue.8 PART 1
, pp. 1425-1431
-
-
Sagel, S.D.1
Kapsner, R.2
Osberg, I.3
-
53
-
-
0031867516
-
Effect of inhaled endotoxin on induced sputum in normal, atopic, and atopic asthmatic subjects
-
Nightingale JA, Rogers DF, Hart LA, et al. Effect of inhaled endotoxin on induced sputum in normal, atopic, and atopic asthmatic subjects. Thorax 1998;53:563-71.
-
(1998)
Thorax
, vol.53
, pp. 563-571
-
-
Nightingale, J.A.1
Rogers, D.F.2
Hart, L.A.3
-
55
-
-
33947588653
-
Innate immune activation in neutrophilic asthma and bronchiectasis
-
Simpson JL, Grissell TV, Douwes J, et al. Innate immune activation in neutrophilic asthma and bronchiectasis. Thorax 2007;62(3):211-8.
-
(2007)
Thorax
, vol.62
, Issue.3
, pp. 211-218
-
-
Simpson, J.L.1
Grissell, T.V.2
Douwes, J.3
-
56
-
-
33745742455
-
Effects of smoking cessation on lung function and airway inflammation in smokers with asthma
-
Chaudhuri R, Livingston E, McMahon AD, et al. Effects of smoking cessation on lung function and airway inflammation in smokers with asthma. Am J Respir Crit Care Med 2006;174:127-33.
-
(2006)
Am J Respir Crit Care Med
, vol.174
, pp. 127-133
-
-
Chaudhuri, R.1
Livingston, E.2
McMahon, A.D.3
-
57
-
-
0032905355
-
The cellular composition of induced sputum in chronic obstructive pulmonary disease
-
Peleman RA, Rytila PH, Kips JC, et al. The cellular composition of induced sputum in chronic obstructive pulmonary disease. Eur Respir J 1999;13:839-43.
-
(1999)
Eur Respir J
, vol.13
, pp. 839-843
-
-
Peleman, R.A.1
Rytila, P.H.2
Kips, J.C.3
-
58
-
-
0029086408
-
Effect of smoking cessation on airway inflammation in chronic bronchitis
-
Turato G, Di Stefano A, Maestrelli P, et al. Effect of smoking cessation on airway inflammation in chronic bronchitis. Am J Respir Crit Care Med 1995;152(4 Pt 1):1262-7.
-
(1995)
Am J Respir Crit Care Med
, vol.152
, Issue.4 PART 1
, pp. 1262-1267
-
-
Turato, G.1
Di Stefano, A.2
Maestrelli, P.3
-
59
-
-
0030071687
-
Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma
-
Keatings VM, Collins PD, Scott DM, Barnes PJ. Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma. Am J Respir Crit Care Med 1996;153:530-4.
-
(1996)
Am J Respir Crit Care Med
, vol.153
, pp. 530-534
-
-
Keatings, V.M.1
Collins, P.D.2
Scott, D.M.3
Barnes, P.J.4
-
60
-
-
0037335886
-
Long-term repeatability of induced sputum cells and inflammatory markers in stable, moderately severe COPD
-
Beeh KM, Beier J, Kornmann O, et al. Long-term repeatability of induced sputum cells and inflammatory markers in stable, moderately severe COPD. Chest 2003;123:778-83.
-
(2003)
Chest
, vol.123
, pp. 778-783
-
-
Beeh, K.M.1
Beier, J.2
Kornmann, O.3
-
61
-
-
0034038342
-
Ongoing airway inflammation in patients with COPD who do not currently smoke
-
Rutgers SR, Postma DS, ten Hacken NH, et al. Ongoing airway inflammation in patients with COPD who do not currently smoke. Chest 2000;117(5 Suppl 1):262S.
-
(2000)
Chest
, vol.117
, Issue.5 SUPPL. 1
-
-
Rutgers, S.R.1
Postma, D.S.2
ten Hacken, N.H.3
-
62
-
-
1042288098
-
The effects of macrolides on inflammatory cells
-
Tamaoki J. The effects of macrolides on inflammatory cells. Chest 2004;125(2 Suppl):41S-50S.
-
(2004)
Chest
, vol.125
, Issue.2 SUPPL.
-
-
Tamaoki, J.1
-
63
-
-
4143127614
-
The effect of clarithromycin on inflammatory markers in chronic obstructive pulmonary disease: Preliminary data
-
Basyigit I, Yildiz F, Ozkara SK, et al. The effect of clarithromycin on inflammatory markers in chronic obstructive pulmonary disease: preliminary data. Ann Pharmacother 2004;38:1400-5.
-
(2004)
Ann Pharmacother
, vol.38
, pp. 1400-1405
-
-
Basyigit, I.1
Yildiz, F.2
Ozkara, S.K.3
-
64
-
-
2942720573
-
The nature of small-airway obstruction in chronic obstructive pulmonary disease
-
Hogg JC, Chu F, Utokaparch S, et al. The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med 2004;350:2645-53.
-
(2004)
N Engl J Med
, vol.350
, pp. 2645-2653
-
-
Hogg, J.C.1
Chu, F.2
Utokaparch, S.3
-
65
-
-
0031855525
-
Neutrophils infiltrating bronchial epithelium in chronic obstructive pulmonary disease
-
Pesci A, Majori M, Cuomo A, et al. Neutrophils infiltrating bronchial epithelium in chronic obstructive pulmonary disease. Respir Med 1998;92:863-70.
-
(1998)
Respir Med
, vol.92
, pp. 863-870
-
-
Pesci, A.1
Majori, M.2
Cuomo, A.3
-
66
-
-
11144357342
-
Neutrophilic infiltration within the ASM in patients with COPD
-
Baraldo S, Turato G, Badin C, et al. Neutrophilic infiltration within the ASM in patients with COPD. Thorax 2004;59:308-12.
-
(2004)
Thorax
, vol.59
, pp. 308-312
-
-
Baraldo, S.1
Turato, G.2
Badin, C.3
-
67
-
-
0029978437
-
Airways obstruction, chronic expectoration, and rapid decline of FEV1 in smokers are associated with increased levels of sputum neutrophils
-
Stanescu D, Sanna A, Veriter C, et al. Airways obstruction, chronic expectoration, and rapid decline of FEV1 in smokers are associated with increased levels of sputum neutrophils. Thorax 1996;51:267-71.
-
(1996)
Thorax
, vol.51
, pp. 267-271
-
-
Stanescu, D.1
Sanna, A.2
Veriter, C.3
-
68
-
-
0032696013
-
Effect of high dose inhaled steroid on cells, cytokines, and proteases in induced sputum in chronic obstructive pulmonary disease
-
Culpitt SV, Maziak W, Loukidis S, et al. Effect of high dose inhaled steroid on cells, cytokines, and proteases in induced sputum in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999;160(5 Pt 1):1635-9.
-
(1999)
Am J Respir Crit Care Med
, vol.160
, Issue.5 PART 1
, pp. 1635-1639
-
-
Culpitt, S.V.1
Maziak, W.2
Loukidis, S.3
-
70
-
-
33646244263
-
Airway inflammation and bronchial bacterial colonization in chronic obstructive pulmonary disease
-
Sethi S, Maloney J, Grove L, et al. Airway inflammation and bronchial bacterial colonization in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2006;173:991-8.
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 991-998
-
-
Sethi, S.1
Maloney, J.2
Grove, L.3
-
71
-
-
0035084103
-
Anti-inflammatory and immunomodulatory potential of the novel PDE4 inhibitor roflumilast in vitro
-
Hatzelmann A, Schudt C. Anti-inflammatory and immunomodulatory potential of the novel PDE4 inhibitor roflumilast in vitro. J Pharmacol Exp Ther 2001;297:267-79.
-
(2001)
J Pharmacol Exp Ther
, vol.297
, pp. 267-279
-
-
Hatzelmann, A.1
Schudt, C.2
-
72
-
-
0035078823
-
In vivo efficacy in airway disease models of roflumilast, a novel orally active PDE4 inhibitor
-
Bundschuh DS, Eltze M, Barsig J, et al. In vivo efficacy in airway disease models of roflumilast, a novel orally active PDE4 inhibitor. J Pharmacol Exp Ther 2001;297:280-90.
-
(2001)
J Pharmacol Exp Ther
, vol.297
, pp. 280-290
-
-
Bundschuh, D.S.1
Eltze, M.2
Barsig, J.3
-
73
-
-
0031680631
-
Effect of theophylline on CD11b and L-selectin expression and density of eosinophils and neutrophils in vitro
-
Spoelstra FM, Berends C, Dijkhuizen B, et al. Effect of theophylline on CD11b and L-selectin expression and density of eosinophils and neutrophils in vitro. Eur Respir J 1998;12:585-91.
-
(1998)
Eur Respir J
, vol.12
, pp. 585-591
-
-
Spoelstra, F.M.1
Berends, C.2
Dijkhuizen, B.3
-
74
-
-
0031935312
-
Effect of PDE4 inhibitors on zymosan-induced IL-8 release from human neutrophils: Synergism with prostanoids and salbutamol
-
Au BT, Teixeira MM, Collins PD, Williams TJ. Effect of PDE4 inhibitors on zymosan-induced IL-8 release from human neutrophils: synergism with prostanoids and salbutamol. Br J Pharmacol 1998;123:1260-6.
-
(1998)
Br J Pharmacol
, vol.123
, pp. 1260-1266
-
-
Au, B.T.1
Teixeira, M.M.2
Collins, P.D.3
Williams, T.J.4
-
75
-
-
0029791441
-
Effects of SCA40 on human isolated bronchus and human polymorphonuclear leukocytes: Comparison with rolipram, SKF94120 and levcromakalim
-
Cortijo J, Villagrasa V, Navarrete C, et al. Effects of SCA40 on human isolated bronchus and human polymorphonuclear leukocytes: comparison with rolipram, SKF94120 and levcromakalim. Br J Pharmacol 1996;119:99-106.
-
(1996)
Br J Pharmacol
, vol.119
, pp. 99-106
-
-
Cortijo, J.1
Villagrasa, V.2
Navarrete, C.3
-
76
-
-
23744451716
-
Roflumilast - an oral anti-inflammatory treatment for chronic obstructive pulmonary disease: A randomised controlled trial
-
Rabe KF, Bateman ED, O'Donnell D, et al. Roflumilast - an oral anti-inflammatory treatment for chronic obstructive pulmonary disease: a randomised controlled trial. Lancet 2005;366:563-71.
-
(2005)
Lancet
, vol.366
, pp. 563-571
-
-
Rabe, K.F.1
Bateman, E.D.2
O'Donnell, D.3
-
77
-
-
33144469314
-
Cilomilast for COPD: Results of a 6-month, placebo-controlled study
-
Rennard SI, Schachter N, Strek M, et al. Cilomilast for COPD: results of a 6-month, placebo-controlled study. Chest 2006;129:56-66.
-
(2006)
Chest
, vol.129
, pp. 56-66
-
-
Rennard, S.I.1
Schachter, N.2
Strek, M.3
-
78
-
-
0142012148
-
Anti-inflammatory effects of the phosphodiesterase-4 inhibitor cilomilast (Ariflo) in chronic obstructive pulmonary disease
-
Gamble E, Grootendorst DC, Brightling CE, et al. Anti-inflammatory effects of the phosphodiesterase-4 inhibitor cilomilast (Ariflo) in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2003;168:976-82.
-
(2003)
Am J Respir Crit Care Med
, vol.168
, pp. 976-982
-
-
Gamble, E.1
Grootendorst, D.C.2
Brightling, C.E.3
-
79
-
-
1842504315
-
The effect of oral clarithromycin on bronchial airway inflammation in moderate-to-severe stable COPD: A randomized controlled trial
-
Banerjee D, Honeybourne D, Khair OA. The effect of oral clarithromycin on bronchial airway inflammation in moderate-to-severe stable COPD: a randomized controlled trial. Treat Respir Med 2004;3:59-65.
-
(2004)
Treat Respir Med
, vol.3
, pp. 59-65
-
-
Banerjee, D.1
Honeybourne, D.2
Khair, O.A.3
-
80
-
-
0028053173
-
Increased nitric oxide in exhaled air of asthmatic patients
-
Kharitonov SA, Yates D, Robbins RA, et al. Increased nitric oxide in exhaled air of asthmatic patients. Lancet 1994;343:133-5.
-
(1994)
Lancet
, vol.343
, pp. 133-135
-
-
Kharitonov, S.A.1
Yates, D.2
Robbins, R.A.3
-
81
-
-
0027427353
-
Increased amount of nitric oxide in exhaled air of asthmatics
-
Alving K, Weitzberg E, Lundberg JM. Increased amount of nitric oxide in exhaled air of asthmatics. Eur Respir J 1993;6:1368-70.
-
(1993)
Eur Respir J
, vol.6
, pp. 1368-1370
-
-
Alving, K.1
Weitzberg, E.2
Lundberg, J.M.3
-
82
-
-
0037338587
-
Prospective evaluation of the validity of exhaled nitric oxide for the diagnosis of asthma
-
Dupont LJ, Demedts MG, Verleden GM. Prospective evaluation of the validity of exhaled nitric oxide for the diagnosis of asthma. Chest 2003;123:751-6.
-
(2003)
Chest
, vol.123
, pp. 751-756
-
-
Dupont, L.J.1
Demedts, M.G.2
Verleden, G.M.3
-
83
-
-
33644773052
-
The use of exhaled nitric oxide concentration to identify eosinophilic airway inflammation: An observational study in adults with asthma
-
Berry MA, Shaw DE, Green RH, et al. The use of exhaled nitric oxide concentration to identify eosinophilic airway inflammation: an observational study in adults with asthma. Clin Exp Allergy 2005;35:1175-9.
-
(2005)
Clin Exp Allergy
, vol.35
, pp. 1175-1179
-
-
Berry, M.A.1
Shaw, D.E.2
Green, R.H.3
-
84
-
-
0035888740
-
Relationship between exhaled nitric oxide and mucosal eosinophilic inflammation in children with difficult asthma, after treatment with oral prednisolone
-
Payne DN, Adcock IM, Wilson NM, et al. Relationship between exhaled nitric oxide and mucosal eosinophilic inflammation in children with difficult asthma, after treatment with oral prednisolone. Am J Respir Crit Care Med 2001;164(8 Pt 1):1376-81.
-
(2001)
Am J Respir Crit Care Med
, vol.164
, Issue.8 PART 1
, pp. 1376-1381
-
-
Payne, D.N.1
Adcock, I.M.2
Wilson, N.M.3
-
85
-
-
19444385389
-
Use of exhaled nitric oxide measurements to guide treatment in chronic asthma
-
Smith AD, Cowan JO, Brassett KP, et al. Use of exhaled nitric oxide measurements to guide treatment in chronic asthma. N Engl J Med 2005;352:2163-73.
-
(2005)
N Engl J Med
, vol.352
, pp. 2163-2173
-
-
Smith, A.D.1
Cowan, J.O.2
Brassett, K.P.3
-
86
-
-
34047166152
-
Asthma exacerbations and exhaled nitric oxide: A randomised controlled trial
-
572s
-
Shaw DE, Berry MA, Thomas M, et al. Asthma exacerbations and exhaled nitric oxide: a randomised controlled trial. Eur Respir J 2006;28 Suppl 50:572s.
-
(2006)
Eur Respir J
, vol.28
, Issue.SUPPL. 50
-
-
Shaw, D.E.1
Berry, M.A.2
Thomas, M.3
-
87
-
-
24644519265
-
Titrating steroids on exhaled nitric oxide in children with asthma: A randomized controlled trial
-
Pijnenburg MW, Bakker EM, Hop WC, de Jongste JC. Titrating steroids on exhaled nitric oxide in children with asthma: a randomized controlled trial. Am J Respir Crit Care Med 2005;172:831-6.
-
(2005)
Am J Respir Crit Care Med
, vol.172
, pp. 831-836
-
-
Pijnenburg, M.W.1
Bakker, E.M.2
Hop, W.C.3
de Jongste, J.C.4
-
88
-
-
23044450101
-
Proteomic study of human bronchoalveolar lavage fluids from smokers with chronic obstructive pulmonary disease by combining surface-enhanced laser desorption/ionization-mass spectrometry profiling with mass spectrometric protein identification
-
Merkel D, Rist W, Seither P, et al. Proteomic study of human bronchoalveolar lavage fluids from smokers with chronic obstructive pulmonary disease by combining surface-enhanced laser desorption/ionization-mass spectrometry profiling with mass spectrometric protein identification. Proteomics 2005;5:2972-80.
-
(2005)
Proteomics
, vol.5
, pp. 2972-2980
-
-
Merkel, D.1
Rist, W.2
Seither, P.3
-
89
-
-
30344474269
-
Proteomic analysis of sputum from adults and children with cystic fibrosis and from control subjects
-
Sloane AJ, Lindner RA, Prasad SS, et al. Proteomic analysis of sputum from adults and children with cystic fibrosis and from control subjects. Am J Respir Crit Care Med 2005;172:1416-26.
-
(2005)
Am J Respir Crit Care Med
, vol.172
, pp. 1416-1426
-
-
Sloane, A.J.1
Lindner, R.A.2
Prasad, S.S.3
-
90
-
-
33646552417
-
Protein profiles of bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis
-
Kriegova E, Melle C, Kolek V, et al. Protein profiles of bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis. Am J Respir Crit Care Med 2006;173:1145-54.
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 1145-1154
-
-
Kriegova, E.1
Melle, C.2
Kolek, V.3
-
92
-
-
33746498593
-
Contribution of alpha- and beta-defensins to lung function decline and infection in smokers: An association study
-
Wallace AM, He JQ, Burkett KM, et al. Contribution of alpha- and beta-defensins to lung function decline and infection in smokers: an association study. Respir Res 2006;7:76.
-
(2006)
Respir Res
, vol.7
, pp. 76
-
-
Wallace, A.M.1
He, J.Q.2
Burkett, K.M.3
-
93
-
-
17844404232
-
Gut microorganisms, mammalian metabolism and personalized health care
-
Nicholson JK, Holmes E, Wilson ID. Gut microorganisms, mammalian metabolism and personalized health care. Nat Rev Microbiol 2005;3:431-8.
-
(2005)
Nat Rev Microbiol
, vol.3
, pp. 431-438
-
-
Nicholson, J.K.1
Holmes, E.2
Wilson, I.D.3
-
94
-
-
0032694577
-
Metabonomics': Understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
-
Nicholson JK, Lindon JC, Holmes E. 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica 1999;29:1181-9.
-
(1999)
Xenobiotica
, vol.29
, pp. 1181-1189
-
-
Nicholson, J.K.1
Lindon, J.C.2
Holmes, E.3
-
95
-
-
33644843042
-
Multi-dimensional phenotyping: Towards a new taxonomy for airway disease
-
Wardlaw AJ, Silverman M, Siva R, et al. Multi-dimensional phenotyping: towards a new taxonomy for airway disease. Clin Exp Allergy 2005;35:1254-62.
-
(2005)
Clin Exp Allergy
, vol.35
, pp. 1254-1262
-
-
Wardlaw, A.J.1
Silverman, M.2
Siva, R.3
-
96
-
-
34547887852
-
Categorising the asthma phenotype: Results of a factor analysis
-
Haldar P, Green RH, Berry M, et al. Categorising the asthma phenotype: results of a factor analysis. Thorax 2006;60 Suppl 2:ii53.
-
(2006)
Thorax
, vol.60
, Issue.SUPPL. 2
-
-
Haldar, P.1
Green, R.H.2
Berry, M.3
-
97
-
-
33750180160
-
Asthma, COPD and bronchitis are just components of airway disease
-
Hargreave FE, Parameswaran K. Asthma, COPD and bronchitis are just components of airway disease. Eur Respir J 2006;28:264-7.
-
(2006)
Eur Respir J
, vol.28
, pp. 264-267
-
-
Hargreave, F.E.1
Parameswaran, K.2
-
98
-
-
33646478111
-
Clinical applications of induced sputum
-
Brightling CE. Clinical applications of induced sputum. Chest 2006;129:1344-8.
-
(2006)
Chest
, vol.129
, pp. 1344-1348
-
-
Brightling, C.E.1
|