Prospective evaluation of the validity of exhaled nitric oxide for the diagnosis of asthma

Chest

Volumn 123, Issue 3, 2003, Pages 751-756

  Dupont, Lieven J ^a   Demedts, Maurits G ^a   Verleden, Geert M ^a  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

Asthma; Breath tests; Diagnostic technique; Exhalation; Nitric oxide; Noninvasive diagnostic method; Pulmonary function tests

Indexed keywords

HISTAMINE; NITRIC OXIDE;

ADOLESCENT; AGED; ARTICLE; ASTHMA; CONTROLLED STUDY; EVALUATION; EXHALATION; FEMALE; FORCED EXPIRATORY VOLUME; GAS ANALYSIS; HUMAN; LUNG FUNCTION; MAJOR CLINICAL STUDY; MALE; MEDICAL ASSESSMENT; MEDICAL SOCIETY; OBSTRUCTIVE AIRWAY DISEASE; OUTPATIENT DEPARTMENT; PATIENT REFERRAL; PREDICTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; SCHOOL CHILD; SMOKING; SYMPTOM;

EID: 0037338587     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.123.3.751     Document Type: Article

References (21)

1. Djukanovic R, Roche WR, Wilson JW, et al. Mucosal inflammation in asthma. Am Rev Respir Dis 1990; 142:434-457
2. Barnes PJ. Pathophysiology of asthma. Br J Clin Pharmacol 1996; 42:3-10
3. National Asthma Education and Prevention Program. Expert panel report 2: guidelines for the diagnosis and management of asthma. Bethesda, MD: National Institutes of Health, 1997; publication No. 97-4051
4. Teeter JG, Bleecker ER. Relationship between airway obstruction and respiratory symptoms in adult asthmatics. Thorax 1998; 113:272-277
5. Sont JK, Han J, van Krieken JM, et al. Relationship between the inflammatory infiltrate in bronchial biopsy specimens and clinical severity of asthma in patients treated with inhaled steroids. Thorax 1996; 51:496-502
6. 1 responses, and methacholine inhalation challenges in the evaluation of suspected asthma. Chest 2001; 119:1001-1010
7. Magnussen H, Holz PO, Sterk PJ, et al. Noninvasive methods to measure airway inflammation: future considerations. Eur Respir J 2000; 16:1175-1179
8. Kharitonov SA, Yates D, Robbins RA, et al. Increased nitric oxide in exhaled air of asthmatic patients. Lancet 1994; 343:133-135
9. Dupont LJ, Rochette F, Demedts MG, et al. Exhaled nitric oxide correlates with airway hyperresponsiveness in steroid-naive patients with mild asthma. Am J Respir Crit Care Med 1998; 157:894-898
10. Kharitonov SA, Barnes PJ. Exhaled markers of pulmonary disease. Am J Respir Crit Care Med 2001; 163:1693-1722
11. Kharitonov SA, Yates DH, Barnes PJ. Inhaled glucocorticoids decrease nitric oxide in exhaled air of asthmatic patients. Am J Respir Crit Care Med 1996; 153:454-457
12. Jatakanon A, Lim S, Kharitonov SA, et al. Correlation between exhaled nitric oxide, sputum eosinophils, and methacholine responsiveness in patients with mild asthma. Thorax 1998; 53:91-95
13. American Thoracic Society. Standardization of spirometry. Am Rev Respir Dis 1987; 136:1285-1298
14. Cockroft DW, Killian DN, Mellon JJ, et al. Bronchial reactivity to inhaled histamine: a method and clinical survey. Clin Allergy 1977; 7:235-243
15. Kharitonov SA, Alving K, Barnes PJ. Exhaled and nasal nitric oxide measurements: recommendations. Eur Respir J 1997; 10:1683-1693
16. Recommendations for standardized procedures for the on-line and off-line measurement of exhaled nitric lower respiratory nitric oxide and nasal nitric oxide in adults and children-1999. Am J Bespir Crit Care Med 1999; 160:2104-2117
17. Chatkin JM, Ansarin K, Silkoff PE, et al. Exhaled nitric oxide as a noninvasive assessment of chronic cough. Am J Respir Crit Care Med 1999; 159:1810-1813
18. Hedenstierna G, Högman M. Can exhaled NO be nsed as a marker of airway inflammation? Eur Respir J 1998; 12:1248-1249
19. Henriksen AH, Lingaas-Holmen T, Sue-Chu M, et al. Combined use of exhaled nitric oxide and airway hyperresponsiveness in characterizing asthma in a large population survey. Eur Respir J 2000; 15:849-855
20. Verleden GM, Dupont LJ, Verpeut AC, et al. The effect of cigarette smoking on exhaled nitric oxide in mild steroid-naive asthmatics. Chest 1999; 116:59-64
21. Silkoff PE, McClean PA, Slutsky AS, et al. Marked flow-dependence of exhaled nitric oxide using a new technique to exclude nasal nitric oxide. Am J Respir Crit Care Med 1997; 155:260-267