Protein profiles of bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis

American Journal of Respiratory and Critical Care Medicine

Volumn 173, Issue 10, 2006, Pages 1145-1154

  Kriegova, Eva ^b   Melle, Christian ^b   Kolek, Vitezslav ^b   Hutyrova, Beata ^b   Mrazek, Frantisek ^b   Bleul, Annett ^b   Du Bois, Roland M ^b   Von Eggeling, Ferdinand ^b   Petrek, Martin ^a  

^a PALACKÝ UNIVERSITY   (Czech Republic)

^b NONE

Author keywords

1 antitrypsin; Albumin; L fgren's syndrome; Protocadherin 2; Surface enhanced laser desorption ionization time of flightmass spectroscopy

Indexed keywords

ALPHA 1 ANTITRYPSIN; SERUM ALBUMIN;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; LUNG LAVAGE; MALE; MASS SPECTROMETRY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RANK SUM TEST; SARCOIDOSIS; THORAX RADIOGRAPHY;

ADULT; AGED; BIOLOGICAL MARKERS; BRONCHOALVEOLAR LAVAGE FLUID; CASE-CONTROL STUDIES; DISEASE PROGRESSION; DOWN-REGULATION; FEMALE; HUMANS; MACROPHAGES, ALVEOLAR; MALE; MIDDLE AGED; PEPTIDE MAPPING; PROBABILITY; PROTEIN ARRAY ANALYSIS; PROTEINS; REFERENCE VALUES; RESPIRATORY FUNCTION TESTS; SARCOIDOSIS, PULMONARY; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; STATISTICS, NONPARAMETRIC; UP-REGULATION;

EID: 33646552417     PISSN: 1073449X     EISSN: 1073449X     Source Type: Journal    
DOI: 10.1164/rccm.200507-1126OC     Document Type: Article

References (65)

1. Baughman RP, Lower EE, du Bois RM. Sarcoidosis. Lancet 2003;361:1111-1118.
2. McGrath DS, Goh N, Foley PJ, du Bois RM. Sarcoidosis: genes and microbes - soil or seed? Sarcoidosis Vasc Diffuse Lung Dis 2001;18:149-164.
3. Kolek V. Sarcoidosis: known and unknown [in Czech]. Prague, Czech Republic: Grada Publishing; 1998.
4. American Thoracic Society, European Respiratory Society, World Association of Sarcoidosis and Other Granulomatous Disorders. Joint statement on sarcoidosis. Am J Respir Crit Care Med 1999;160:736-755.
5. Agostini C, Miorin M, Semenzato G. Gene expression profile analysis by DNA microarrays: a new approach to assess functional genomics in diseases. Sarcoidosis Vasc Diffuse Lung Dis 2002;19:5-9.
6. Rutherford RM, Staedtler F, Kehren J, Chibout SD, Joos L, Tamm M, Gilmartin JJ, Brutsche MH. Functional genomics and prognosis in sarcoidosis: the critical role of antigen presentation. Sarcoidosis Vasc Diffuse Lung Dis 2004;21:10-18.
7. Boggs SE. Protein profiling in respiratory disease: techniques and impact. Expert Rev Proteomics 2004;1:29-36.
8. Hirsch J, Hansen KC, Burlingame AL, Matthay MA. Proteomics: current techniques and potential applications to lung disease. Am J Physiol Lung Cell Mol Physiol 2004;287:L1-L23.
9. Wattiez R, Falmagne P. Proteomics of bronchoalveolar lavage fluid. J Chromatogr B Analyt Technol Biomed Life Sci 2005;815:169-178.
10. Sepper R, Prikk K. Proteomics: is it an approach to understand the progression of chronic lung disorders? J Proteome Res 2004;3:277-281.
11. Wattiez R, Hermans C, Bernard A, Lesur O, Falmagne P. Human bronchoalveolar lavage fluid: two-dimensional gel electrophoresis, amino acid microsequencing and identification of major proteins. Electrophoresis 1999;20:1634-1645.
12. Wattiez R, Hermans C, Cruyt C, Bernard A, Falmagne P. Human bronchoalveolar lavage fluid protein two-dimensional database: study of interstitial lung diseases. Electrophoresis 2000;21:2703-2712.
13. Sabounchi-Schutt F, Astrom J, Hellman U, Eklund A, Grunewald J. Changes in bronchoalveolar lavage fluid proteins in sarcoidosis: a proteomics approach. Eur Respir J 2003;21:414-420.
14. Magi B, Bini L, Perari MG, Fossi A, Sanchez JC, Hochstrasser D, Paesano S, Raggiaschi R, Santucci A, Pallini V, et al. Bronchoalveolar lavage fluid protein composition in patients with sarcoidosis and idiopathic pulmonary flbrosis: a two-dimensional electrophoretic study. Electrophoresis 2002;23:3434-3444.
15. Noel-Georis I, Bernard A, Falmagne P, Wattiez R. Database of bronchoalveolar lavage fluid proteins. J Chromatogr B Analyt Technol Biomed Life Sci 2002;771:221-236.
16. Rottoli P, Magi B, Perari MG, Liberatori S, Nikiforakis N, Bargagli E, Cianti R, Bini L, Pallini V. Cytokine profile and proteome analysis in bronchoalveolar lavage of patients with sarcoidosis, pulmonary fibrosis associated with systemic sclerosis and idiopathic pulmonary fibrosis. Proteomics 2005;5:1423-1430.
17. Hermans C, Petrek M, Kolek V, Weynand B, Pieters T, Lambert M, Bernard A. Serum Clara cell protein (CC16), a marker of the integrity of the air-blood barrier in sarcoidosis. Eur Respir J 2001;18:507-514.
18. Gibejova A, Mrazek F, Subrtova D, Sekerova V, Szotkowska J, Kolek V, du Bois RM, Petrek M. Expression of macrophage inflammatory protein-3β/CCL19 in pulmonary sarcoidosis. Am J Respir Crit Care Med 2003;167:1695-1703.
19. Suga M, Iyonaga K, Ichiyasu H, Saita N, Yamasaki H, Ando M. Clinical significance of MCP-1 levels in BALF and serum in patients with interstitial lung diseases. Eur Respir J 1999;14:376-382.
20. Petrek M, Kolek V, Szotkowska J, du Bois RM. CC and C chemokine expression in pulmonary sarcoidosis. Eur Respir J 2002;20:1206-1212.
21. Petrek M, Pantelidis P, Southcott AM, Lympany P, Safranek P, Black CM, Kolek V, Weigl E, du Bois RM. The source and role of RANTES in interstitial lung disease. Eur Respir J 1997;10:1207-1216.
22. Capelli A, Di Stefano A, Lusuardi M, Gnemmi I, Donner CF. Increased macrophage inflammatory protein-1α and macrophage inflammatory protein-1β levels in bronchoalveolar lavage fluid of patients affected by different stages of pulmonary sarcoidosis. Am J Respir Crit Care Med 2002;165:236-241.
23. Miotto D, Christodoulopoulos P, Olivenstein R, Taha R, Cameron L, Tsicopoulos A, Tonnel AB, Fahy O, Lafitte JJ, Luster AD, et al. Expression of IFN-γ-inducible protein; monocyte chemotactic proteins 1, 3, and 4; and eotaxin in TH1- and TH2-mediated lung diseases. J Allergy Clin Immunol 2001;107:664-670.
24. Pantelidis P, Southcott AM, Black CM, Du Bois RM. Up-regulation of IL-8 secretion by alveolar macrophages from patients with fibrosing alveolitis: a subpopulation analysis. Clin Exp Immunol 1997;108:95-104.
25. Agostini C, Meneghin A, Semenzato G. T-lymphocytes and cytokines in sarcoidosis. Curr Opin Pulm Med 2002;8:435-440.
26. Tang N, Tornatore P, Weinberger SR. Current developments in SELDI affinity technology. Mass Spectrom Rev 2004;23:34-44.
27. von Eggeling F, Davies H, Lomas L, Fiedler W, Junker K, Claussen U, Ernst G. Tissue-specific microdissection coupled with ProteinChip array technologies: applications in cancer research. Biotechniques 2000;29:1066-1070.
28. Petricoin EE, Paweletz CP, Liotta LA. Clinical applications of proteomics: proteomic pattern diagnostics. J Mammary Gland Biol Neoplasia 2002;7:433-440.
29. Melle C, Ernst G, Schimmel B, Bleul A, Koscielny S, Wiesner A, Bogumil R, Moller U, Osterloh D, Halbhuber KJ, et al. A technical triade for proteomic identification and characterization of cancer biomarkers. Cancer Res 2004;64:4099-4104.
30. Wiesner A. Detection of tumor markers with ProteinChip technology. Curr Pharm Biotechnol 2004;5:45-67.
31. Silzbach LE. Sarcoidosis: clinical features and management. Med Clin North Am 1967;51:483-502.
32. Kriegova E, Melle C, Bleul A, Mrazek F, Kolek V, von Eggeling F, Petrek M. Determination of a typical protein expression profile in bronchoalveolar lavage fluid (BALF) from patients with pulmonary sarcoidosis using SELDI-mass spectrometry [abstract]. Eur Respir J 2005;26:468.
33. Petrek M, Kolek V. T-lymphocyte subpopulations in bronchoalveolar lavage in pulmonary sarcoidosis and other interstitial pulmonary diseases [in Czech]. Cas Lek Cesk 1993;132:365-368.
34. Melle C, Bogumil R, Ernst G, Schimmel B, Bleul A, von Eggeling F. Detection and identification of heat shock protein 10 as a biomarker in colorectal cancer by protein profiling. Proteomics 2006;6:2600-2608.
35. Melle C, Ernst G, Schimmel B, Bleul A, Koscielny S, Wiesner A, Bogumil R, Moller U, Osterloh D, Halbhuber KJ, et al. Biomarker discovery and identification in laser microdissected head and neck squamous cell carcinoma with ProteinChip technology, two-dimensional gel electrophoresis, tandem mass spectrometry, and immunohistochemistry. Mol Cell Proteomics 2003;2:443-552.
36. Melle C, Ernst G, Schimmel B, Bleul A, Kaufmann R, Hommann M, Richter KK, Daffner W, Settmacher U, Claussen U, et al. Characterization of pepsinogen C as a potential biomarker for gastric cancer using a histo-proteomic approach. J Proteome Res 2005;4:1799-1804.
37. Müller-Quernheim J. Sarcoidosis: immunopathogenetic concepts and their clinical application. Eur Respir J 1998;12:716-738.
38. Lynch JP, White ES. Pulmonary sarcoidosis. In: Drent M, Costabel U, editors. Sarcoidosis. European Respiratory Monograph 32. Geneva, Switzerland: ERS Press; 2005. pp. 105-129.
39. Sato H, Grutters JC, Pantelidis P, Mizzon AN, Ahmad T, Van Houte AJ, Lammers JW, Van Den Bosch JM, Welsh KI, Du Bois RM. HLA-DQB1* 0201: amarker for good prognosis in British and Dutch patients with sarcoidosis. Am J Respir Cell Mol Biol 2002;27:406-412.
40. Seitzer U, Swider C, Stuber F, Suchnicki K, Lange A, Richter E, Zabel P, Müller-Quernheim J, Flad HD, Gerdes J. Tumour necrosis factor α promoter gene polymorphism in sarcoidosis. Cytokine 1997;9:787-790.
41. Mrazek F, Holla LI, Hutyrova B, Znojil V, Vasku A, Kolek V, Welsh KI, Vacha J, du Bois RM, Petrek M. Association of tumour necrosis factor-α, lymphotoxin-α and HLA-DRB1 gene polymorphisms with Lofgren's syndrome in Czech patients with sarcoidosis. Tissue Antigens 2005;65:163-171.
42. Spagnolo P, Renzoni EA, Wells AU, Sato H, Grutters JC, Sestini P, Abdallah A, Gramiccioni E, Ruven HJ, du Bois RM, et al. C-C chemokine receptor 2 and sarcoidosis: association with Lofgren's syndrome. Am J Respir Crit Care Med 2003;168:1162-1166.
43. Reynolds HY. Use of bronchoalveolar lavage in humans: past necessity and future imperative. Lung 2000;178:271-293.
44. du Bois RM. Diffuse lung disease: an approach to management. BMJ 1994;309:175-179.
45. Plymoth A, Lofdahl CG, Ekberg-Jansson A, Dahlback M, Lindberg H, Fehniger TE, Marko-Varga G. Human bronchoalveolar lavage: biofluid analysis with special emphasis on sample preparation. Proteomics 2003;3:962-972.
46. Merkel D, Rist W, Seither P, Weith A, Lenter MC. Proteomic study of human bronchoalveolar lavage fluids from smokers with chronic obstructive pulmonary disease by combining surface-enhanced laser desorption/ionization-mass spectrometry profiling with mass spectrometric protein identification. Proteomics 2005;5:2972-2980.
47. Lenz AG, Meyer B, Constabel U, Maier K. Bronchoalveolar lavage fluid proteins in human lung disease: analysis by two-dimensional electrophoresis. Electrophoresis 1993;14:242-244.
48. Liggett WS, Barker PE, Semmes OJ, Cazares LH. Measurement reproducibility in the early stages of biomarker development. Dis Markers 2004;20:295-307.
49. Semmes OJ, Feng Z, Adam BL, Banez LL, Bigbee WL, Campos D, Cazares LH, Chan DW, Grizzle WE, Izbicka E, et al. Evaluation of serum protein profiling by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry for the detection of prostate cancer. I. Assessment of platform reproducibility. Clin Chem 2005;51:102-112.
50. Vorderwulbecke S, Cleverly S, Weinberger SR, Wiesner A. Protein quantification by SELDI-TOF-MS-based ProteinChip system. Nat Methods 2005;2:393-395.
51. Chamrad D, Meyer HE. Valid data from large-scale proteomics studies. Nat Methods 2005;2:647-648.
52. Kang S, Kim JW, Kang GH, Lee S, Park NH, Song YS, Park SY, Kang SB, Lee HP. Comparison of DNA hypermethylation patterns in different types of uterine cancer: cervical squamous cell carcinoma, cervical adenocarcinoma and endometrial adenocarcinoma. Int J Cancer 2005;118:2168-2171.
53. Lin MT, Storer B, Martin PJ, Tseng LH, Gooley T, Chen PJ, Hansen JA. Relation of an interleukin-10 promoter polymorphism to graft-versus-host disease and survival after hematopoietic-cell transplantation. N Engl J Med 2003;349:2201-2210.
54. Melle C, Kaufmann R, Hommann M, Bleul A, Driesch D, Ernst G, von Eggeling F. Proteomic profiling in microdissected hepatocellular carcinoma tissue using ProteinChip technology. Int J Oncol 2004;24:885-891.
55. Sauter ER, Shan S, Hewett JE, Speckman P, Du Bois GC. Proteomic analysis of nipple aspirate fluid using SELDI-TOF-MS. Int J Cancer 2005;114:791-796.
56. Ward C, Fenwick J, Booth H, Walters EH. Albumin is not suitable as amarker of bronchoalveolar lavage dilution in interstitial lung disease. Eur Respir J 1997;10:2029-2033.
57. Roberts CM, Cairns D, Bryant DH, Burke WM, Yeates M, Blake H, Penny R, Shelley L, Zaunders JJ, Breit SN. Changes in epithelial lining fluid albumin associated with smoking and interstitial lung disease. Eur Respir J 1993;6:110-115.
58. Baughman RP. The uncertainties of bronchoalveolar lavage. Eur Respir J 1997;10:1940-1942.
59. 1-Antitrypsin deficiency. Lancet 2005;365:2225-2236.
60. 1-antitrypsin. Am J Respir Cell Mol Biol 2000;22:244-252.
61. 1-antitrypsin. Biochem Biophys Res Commun 2004;321:592-600.
62. 1-antitrypsin on primary human monocytes, in vitro. BMC Cell Biol 2004;5:11-21.
63. Nollet F, Kools P, van Roy F. Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members. J Mol Biol 2000;299:551-572.
64. Omi H, Kitagawa M. Studies on protocadherin-2 expression in the human fetal central nervous system. Congenit Anom (Kyoto) 2004;44:147-155.
65. Ying J, Li H, Seng TJ, Langford C, Srivastava G, Tsao SW, Putti T, Murray P, Chan AT, Tao Q. Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation. Oncogene 2006;25:1070-1080.