메뉴 건너뛰기




Volumn 67, Issue 9, 2007, Pages 1232-1247

Polyphosphoinositol lipids: Under-PPInning synaptic function in health and disease

Author keywords

Exocytosis; Neurotransmitter release; Phosphatidylinositol 4 kinase; Phospholipase C; PtdIns(4,5)P2; Synapse

Indexed keywords

PHOSPHATIDYLINOSITIDE; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLINOSITOL 4 PHOSPHATE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE;

EID: 34547805175     PISSN: 19328451     EISSN: 1932846X     Source Type: Journal    
DOI: 10.1002/dneu.20509     Document Type: Review
Times cited : (15)

References (137)
  • 1
    • 0023146564 scopus 로고
    • Evidence that inositol 1-phosphate in brain of lithium-treated rats results mainly from phosphatidylinositol metabolism
    • Ackermann KE, Gish BG, Honchar MP, Sherman WR. 1987. Evidence that inositol 1-phosphate in brain of lithium-treated rats results mainly from phosphatidylinositol metabolism. Biochem J 242:517-524.
    • (1987) Biochem J , vol.242 , pp. 517-524
    • Ackermann, K.E.1    Gish, B.G.2    Honchar, M.P.3    Sherman, W.R.4
  • 4
    • 27744547034 scopus 로고    scopus 로고
    • Properties of synaptic vesicle pools in mature central nerve terminals
    • Ashton AC, Ushkaryov YA. 2005. Properties of synaptic vesicle pools in mature central nerve terminals. J Biol Chem 280:37278-37288.
    • (2005) J Biol Chem , vol.280 , pp. 37278-37288
    • Ashton, A.C.1    Ushkaryov, Y.A.2
  • 5
    • 10044225690 scopus 로고    scopus 로고
    • Coupling actin and membrane dynamics during calcium-regulated exocytosis: A role for Rho and ARF GTPases
    • Bader MF, Doussau F, Chasserot-Golaz S, Vitale N, Gasman S. 2004. Coupling actin and membrane dynamics during calcium-regulated exocytosis: A role for Rho and ARF GTPases. Biochim Biophys Acta 1742:37-49.
    • (2004) Biochim Biophys Acta , vol.1742 , pp. 37-49
    • Bader, M.F.1    Doussau, F.2    Chasserot-Golaz, S.3    Vitale, N.4    Gasman, S.5
  • 6
    • 1542286172 scopus 로고    scopus 로고
    • The C2 domains of synaptotagmin-partners in exocytosis
    • Bai J, Chapman ER. 2004. The C2 domains of synaptotagmin-partners in exocytosis. Trends Biochem Sci 29:143-151.
    • (2004) Trends Biochem Sci , vol.29 , pp. 143-151
    • Bai, J.1    Chapman, E.R.2
  • 7
    • 0842291506 scopus 로고    scopus 로고
    • 2 increases the speed of response of synaptotagmin and steers its membrane-penetration activity toward the plasma membrane
    • 2 increases the speed of response of synaptotagmin and steers its membrane-penetration activity toward the plasma membrane. Nat Struct Mol Biol 11:36-44.
    • (2004) Nat Struct Mol Biol , vol.11 , pp. 36-44
    • Bai, J.1    Tucker, W.C.2    Chapman, E.R.3
  • 8
    • 0037205494 scopus 로고    scopus 로고
    • Characterization of type II phosphatidylinositol 4-kinase isoforms reveals association of the enzymes with endosomal vesicular compartments
    • Balla A, Tuymetova G, Barshishat M, Geiszt M, Balla T. 2002. Characterization of type II phosphatidylinositol 4-kinase isoforms reveals association of the enzymes with endosomal vesicular compartments. J Biol Chem 277:20041-20050.
    • (2002) J Biol Chem , vol.277 , pp. 20041-20050
    • Balla, A.1    Tuymetova, G.2    Barshishat, M.3    Geiszt, M.4    Balla, T.5
  • 9
    • 0033807922 scopus 로고    scopus 로고
    • Immunohistochemical localisation of two phosphatidylinositol 4-kinase isoforms, PI4K230 and PI4K92, in the central nervous system of rats
    • Balla A, Vereb G, Gulkan H, Gehrmann T, Gergely P, Heilmeyer LM Jr, Antal M. 2000. Immunohistochemical localisation of two phosphatidylinositol 4-kinase isoforms, PI4K230 and PI4K92, in the central nervous system of rats. Exp Brain Res 134:279-288.
    • (2000) Exp Brain Res , vol.134 , pp. 279-288
    • Balla, A.1    Vereb, G.2    Gulkan, H.3    Gehrmann, T.4    Gergely, P.5    Heilmeyer Jr, L.M.6    Antal, M.7
  • 10
    • 0032497834 scopus 로고    scopus 로고
    • Phosphatidylinositol 4-kinases
    • Balla T. 1998. Phosphatidylinositol 4-kinases. Biochim Biophys Acta 1436:69-85.
    • (1998) Biochim Biophys Acta , vol.1436 , pp. 69-85
    • Balla, T.1
  • 12
    • 0024341795 scopus 로고
    • Neural and developmental actions of lithium: A unifying hypothesis
    • Berridge MJ, Downes CP, Hanley MR. 1989. Neural and developmental actions of lithium: A unifying hypothesis. Cell 59:411-419.
    • (1989) Cell , vol.59 , pp. 411-419
    • Berridge, M.J.1    Downes, C.P.2    Hanley, M.R.3
  • 13
    • 0024453294 scopus 로고
    • Inositol phosphates and cell signalling
    • Berridge MJ, Irvine RF. 1989. Inositol phosphates and cell signalling. Nature 341:197-205.
    • (1989) Nature , vol.341 , pp. 197-205
    • Berridge, M.J.1    Irvine, R.F.2
  • 15
    • 0036905264 scopus 로고    scopus 로고
    • Move over protein kinase C, you've got company: Alternative cellular effectors of di-acylglycerol and phorbol esters
    • Brose N, Rosenmund C. 2002. Move over protein kinase C, you've got company: Alternative cellular effectors of di-acylglycerol and phorbol esters. J Cell Sci 115:4399-4411.
    • (2002) J Cell Sci , vol.115 , pp. 4399-4411
    • Brose, N.1    Rosenmund, C.2
  • 16
    • 25844454807 scopus 로고    scopus 로고
    • Coincidence detection in phosphoinositide signaling
    • Carlton JG, Cullen PJ. 2005. Coincidence detection in phosphoinositide signaling. Trends Cell Biol 15:540-547.
    • (2005) Trends Cell Biol , vol.15 , pp. 540-547
    • Carlton, J.G.1    Cullen, P.J.2
  • 17
    • 14144255234 scopus 로고    scopus 로고
    • Akt activation is necessary for growth factor-induced trafficking of functional K(Ca) channels in developing parasympathetic neurons
    • Chae KS, Martin-Caraballo M, Anderson M, Dryer SE. 2005. Akt activation is necessary for growth factor-induced trafficking of functional K(Ca) channels in developing parasympathetic neurons. J Neurophysiol 93:1174-1182.
    • (2005) J Neurophysiol , vol.93 , pp. 1174-1182
    • Chae, K.S.1    Martin-Caraballo, M.2    Anderson, M.3    Dryer, S.E.4
  • 19
    • 30944456676 scopus 로고    scopus 로고
    • The latest phospholipase C, PLCη, is implicated in neuronal function
    • Cockcroft S. 2006. The latest phospholipase C, PLCη, is implicated in neuronal function. Trends Biochem Sci 31:4-7.
    • (2006) Trends Biochem Sci , vol.31 , pp. 4-7
    • Cockcroft, S.1
  • 20
    • 0042490720 scopus 로고    scopus 로고
    • Synapsin I-associated phosphati-dylinositol 3-kinase mediates synaptic vesicle delivery to the readily releasable pool
    • Cousin MA, Malladi CS, Tan TC, Raymond CR, Smillie KJ, Robinson PJ. 2003. Synapsin I-associated phosphati-dylinositol 3-kinase mediates synaptic vesicle delivery to the readily releasable pool. J Biol Chem 278:29065-29071.
    • (2003) J Biol Chem , vol.278 , pp. 29065-29071
    • Cousin, M.A.1    Malladi, C.S.2    Tan, T.C.3    Raymond, C.R.4    Smillie, K.J.5    Robinson, P.J.6
  • 22
    • 34547817424 scopus 로고
    • Studies on the labelling of brain phospholipids with radioactive phosphorus
    • Dawson RM. 1954. Studies on the labelling of brain phospholipids with radioactive phosphorus. Biochem J 57:237-245.
    • (1954) Biochem J , vol.57 , pp. 237-245
    • Dawson, R.M.1
  • 23
    • 0348047605 scopus 로고    scopus 로고
    • Functional organization of PLC signaling microdomains in neurons
    • Delmas P, Crest M, Brown DA. 2004. Functional organization of PLC signaling microdomains in neurons. Trends Neurosci 27:41-47.
    • (2004) Trends Neurosci , vol.27 , pp. 41-47
    • Delmas, P.1    Crest, M.2    Brown, D.A.3
  • 24
    • 20544464167 scopus 로고    scopus 로고
    • The role of the phosphoinositides at the Golgi complex
    • De Matteis MA, Di Campli A, Godi A. 2005. The role of the phosphoinositides at the Golgi complex. Biochim Biophys Acta 1744:396-405.
    • (2005) Biochim Biophys Acta , vol.1744 , pp. 396-405
    • De Matteis, M.A.1    Di Campli, A.2    Godi, A.3
  • 25
    • 33749836234 scopus 로고    scopus 로고
    • Phosphoinositides in cell regulation and membrane dynamics
    • Di Paolo G, De Camilli P. 2006. Phosphoinositides in cell regulation and membrane dynamics. Nature 443:651-657.
    • (2006) Nature , vol.443 , pp. 651-657
    • Di Paolo, G.1    De Camilli, P.2
  • 28
    • 0030884527 scopus 로고    scopus 로고
    • Cloning of a human phosphoinositide 3-kinase with a C2 domain that displays reduced sensitivity to the inhibitor wortmannin
    • Domin J, Pages F, Volinia S, Rittenhouse SE, Zvelebil MJ, Stein RC, Waterfield MD. 1997. Cloning of a human phosphoinositide 3-kinase with a C2 domain that displays reduced sensitivity to the inhibitor wortmannin. Biochem J 326:139-147.
    • (1997) Biochem J , vol.326 , pp. 139-147
    • Domin, J.1    Pages, F.2    Volinia, S.3    Rittenhouse, S.E.4    Zvelebil, M.J.5    Stein, R.C.6    Waterfield, M.D.7
  • 29
    • 0025330471 scopus 로고
    • Evidence that the inositol phospholipids are necessary for exocytosis. Loss of inositol phospholipids and inhibition of secretion in permeabilized cells caused by a bacterial phospholipase C and removal of ATP
    • Eberhard DA, Cooper CL, Low MG, Holz RW. 1990. Evidence that the inositol phospholipids are necessary for exocytosis. Loss of inositol phospholipids and inhibition of secretion in permeabilized cells caused by a bacterial phospholipase C and removal of ATP. Biochem J 268:15-25.
    • (1990) Biochem J , vol.268 , pp. 15-25
    • Eberhard, D.A.1    Cooper, C.L.2    Low, M.G.3    Holz, R.W.4
  • 30
    • 0026070950 scopus 로고
    • A monoclonal antibody distinguishes two types of phosphatidylinositol 4-kinase
    • Endemann GC, Graziani A, Cantley LC. 1991. A monoclonal antibody distinguishes two types of phosphatidylinositol 4-kinase. Biochem J 273:63-66.
    • (1991) Biochem J , vol.273 , pp. 63-66
    • Endemann, G.C.1    Graziani, A.2    Cantley, L.C.3
  • 31
    • 33644970939 scopus 로고    scopus 로고
    • Protein kinase B/Akt is a novel cysteine string protein kinase that regulates exocytosis release kinetics and quantal size
    • Evans GJ, Barclay JW, Prescott GR, Jo SR, Burgoyne RD, Birnbaum MJ, Morgan A. 2006. Protein kinase B/Akt is a novel cysteine string protein kinase that regulates exocytosis release kinetics and quantal size. J Biol Chem 281:1564-1572.
    • (2006) J Biol Chem , vol.281 , pp. 1564-1572
    • Evans, G.J.1    Barclay, J.W.2    Prescott, G.R.3    Jo, S.R.4    Burgoyne, R.D.5    Birnbaum, M.J.6    Morgan, A.7
  • 32
    • 12144289874 scopus 로고    scopus 로고
    • The kinetics of synaptic vesicle pool depletion at CNS synaptic terminals
    • Fernandez-Alfonso T, Ryan TA. 2004. The kinetics of synaptic vesicle pool depletion at CNS synaptic terminals. Neuron 41:943-953.
    • (2004) Neuron , vol.41 , pp. 943-953
    • Fernandez-Alfonso, T.1    Ryan, T.A.2
  • 33
    • 0036677944 scopus 로고    scopus 로고
    • Inositol and higher inositol phosphates in neural tissues: Homeostasis, metabolism and functional significance
    • Fisher SK, Novak JE, Agranoff BW. 2002. Inositol and higher inositol phosphates in neural tissues: Homeostasis, metabolism and functional significance. J Neurochem 82:736-754.
    • (2002) J Neurochem , vol.82 , pp. 736-754
    • Fisher, S.K.1    Novak, J.E.2    Agranoff, B.W.3
  • 36
    • 2342503205 scopus 로고    scopus 로고
    • A novel neuronal-specific splice variant of Type I phosphatidylinositol 4-phosphate 5-kinase isoform γ
    • Giudici ML, Emson PC, Irvine RF. 2004. A novel neuronal-specific splice variant of Type I phosphatidylinositol 4-phosphate 5-kinase isoform γ. Biochem J 379:489-496.
    • (2004) Biochem J , vol.379 , pp. 489-496
    • Giudici, M.L.1    Emson, P.C.2    Irvine, R.F.3
  • 37
    • 0036705074 scopus 로고    scopus 로고
    • Signaling networks in the pathophysiology and treatment of mood disorders
    • Gould TD, Manji HK. 2002. Signaling networks in the pathophysiology and treatment of mood disorders. J Psychosom Res 53:687-697.
    • (2002) J Psychosom Res , vol.53 , pp. 687-697
    • Gould, T.D.1    Manji, H.K.2
  • 38
    • 33748576937 scopus 로고    scopus 로고
    • Clathrin-mediated endocytosis is the dominant mechanism of vesicle retrieval at hippocampal synapses
    • Granseth B, Odermatt B, Royle SJ, Lagnado L. 2006. Clathrin-mediated endocytosis is the dominant mechanism of vesicle retrieval at hippocampal synapses. Neuron 51:773-786.
    • (2006) Neuron , vol.51 , pp. 773-786
    • Granseth, B.1    Odermatt, B.2    Royle, S.J.3    Lagnado, L.4
  • 39
    • 0037386564 scopus 로고    scopus 로고
    • Phosphatidylinositol 4-kinase type IIα is responsible for the phosphatidylinositol 4-kinase activity associated with synaptic vesicles
    • Guo J, Wenk MR, Pellegrini L, Onofri F, Benfenati F, De Camilli P. 2003. Phosphatidylinositol 4-kinase type IIα is responsible for the phosphatidylinositol 4-kinase activity associated with synaptic vesicles. Proc Natl Acad Sci USA 100:3995-4000.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 3995-4000
    • Guo, J.1    Wenk, M.R.2    Pellegrini, L.3    Onofri, F.4    Benfenati, F.5    De Camilli, P.6
  • 40
    • 33646120563 scopus 로고    scopus 로고
    • Requirement of Akt to mediate long-term synaptic depression in Drosophila
    • Guo HF, Zhong Y. 2006. Requirement of Akt to mediate long-term synaptic depression in Drosophila. J Neurosci 26:4004-4014.
    • (2006) J Neurosci , vol.26 , pp. 4004-4014
    • Guo, H.F.1    Zhong, Y.2
  • 41
    • 21644486050 scopus 로고    scopus 로고
    • Imaging phosphoinositide dynamics using GFP-tagged protein domains
    • Halet G. 2005. Imaging phosphoinositide dynamics using GFP-tagged protein domains. Biol Cell 97:501-518.
    • (2005) Biol Cell , vol.97 , pp. 501-518
    • Halet, G.1
  • 43
    • 33745224777 scopus 로고    scopus 로고
    • Elimination of plasma membrane phosphatidylinositol (4,5)-bisphosphate is required for exocytosis from mast cells
    • Hammond GR, Dove SK, Nicol A, Pinxteren JA, Zicha D, Schiavo G. 2006. Elimination of plasma membrane phosphatidylinositol (4,5)-bisphosphate is required for exocytosis from mast cells. J Cell Sci 119:2084-2094.
    • (2006) J Cell Sci , vol.119 , pp. 2084-2094
    • Hammond, G.R.1    Dove, S.K.2    Nicol, A.3    Pinxteren, J.A.4    Zicha, D.5    Schiavo, G.6
  • 44
    • 12344329222 scopus 로고    scopus 로고
    • Lithium and bipolar mood disorder: The inositol-depletion hypothesis revisited
    • Harwood AJ. 2005. Lithium and bipolar mood disorder: The inositol-depletion hypothesis revisited. Mol Psychiatry 10:117-126.
    • (2005) Mol Psychiatry , vol.10 , pp. 117-126
    • Harwood, A.J.1
  • 45
    • 28844478464 scopus 로고    scopus 로고
    • Phosphoinositide regulation of clathrin-mediated endocytosis
    • Haucke V. 2005. Phosphoinositide regulation of clathrin-mediated endocytosis. Biochem Soc Trans 33:1285-1289.
    • (2005) Biochem Soc Trans , vol.33 , pp. 1285-1289
    • Haucke, V.1
  • 47
  • 48
    • 0033175467 scopus 로고    scopus 로고
    • Yeast homologue of neuronal frequenin is a regulator of phosphatidylinositol-4-OH kinase
    • Hendricks KB, Wang BQ, Schnieders EA, Thorner J. 1999. Yeast homologue of neuronal frequenin is a regulator of phosphatidylinositol-4-OH kinase. Nat Cell Biol 1:234-241.
    • (1999) Nat Cell Biol , vol.1 , pp. 234-241
    • Hendricks, K.B.1    Wang, B.Q.2    Schnieders, E.A.3    Thorner, J.4
  • 49
    • 0042568798 scopus 로고    scopus 로고
    • Neuronal calcium sensor-1: A multifunctional regulator of secretion
    • Hilfiker S. 2003. Neuronal calcium sensor-1: A multifunctional regulator of secretion. Biochem Soc Trans 31:828-832.
    • (2003) Biochem Soc Trans , vol.31 , pp. 828-832
    • Hilfiker, S.1
  • 51
    • 0005521383 scopus 로고
    • Effects of acetylcholine on the turnover of phosphoryl units in individual phospholipids of pancreas slices and brain cortex slices
    • Hokin LE, Hokin MR. 1955. Effects of acetylcholine on the turnover of phosphoryl units in individual phospholipids of pancreas slices and brain cortex slices. Biochim Biophys Acta 18:102-110.
    • (1955) Biochim Biophys Acta , vol.18 , pp. 102-110
    • Hokin, L.E.1    Hokin, M.R.2
  • 52
    • 0034625410 scopus 로고    scopus 로고
    • 2 as being important in exocytosis. J Biol Chem 275:17878-17885.
    • 2 as being important in exocytosis. J Biol Chem 275:17878-17885.
  • 56
    • 33645652013 scopus 로고    scopus 로고
    • Rolling blackout is required for synaptic vesicle exocytosis
    • Huang FD, Woodruff E, Mohrmann R, Broadie K. 2006. Rolling blackout is required for synaptic vesicle exocytosis. J Neurosci 26:2369-2379.
    • (2006) J Neurosci , vol.26 , pp. 2369-2379
    • Huang, F.D.1    Woodruff, E.2    Mohrmann, R.3    Broadie, K.4
  • 58
    • 22144495354 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a novel phospholipase C, PLCη
    • Hwang JI, Oh YS, Shin KJ, Kim H, Ryu SH, Suh PG. 2005. Molecular cloning and characterization of a novel phospholipase C, PLCη. Biochem J 389:181-186.
    • (2005) Biochem J , vol.389 , pp. 181-186
    • Hwang, J.I.1    Oh, Y.S.2    Shin, K.J.3    Kim, H.4    Ryu, S.H.5    Suh, P.G.6
  • 61
    • 0035347166 scopus 로고    scopus 로고
    • Back in the water: The return of the inositol phosphates
    • Irvine RF, Schell MJ. 2001. Back in the water: The return of the inositol phosphates. Nat Rev Mol Cell Biol 2:327-338.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 327-338
    • Irvine, R.F.1    Schell, M.J.2
  • 63
    • 3543074534 scopus 로고    scopus 로고
    • Cytoskeletal regulation: Rich in lipids
    • Janmey PA, Lindberg U. 2004. Cytoskeletal regulation: Rich in lipids. Nat Rev Mol Cell Biol 5:658-666.
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 658-666
    • Janmey, P.A.1    Lindberg, U.2
  • 64
    • 0028346383 scopus 로고
    • Type I phosphatidylinositol 4-phosphate 5-kinase isoforms are specifically stimulated by phosphatidic acid
    • Jenkins GH, Fisette PL, Anderson RA. 1994. Type I phosphatidylinositol 4-phosphate 5-kinase isoforms are specifically stimulated by phosphatidic acid. J Biol Chem 269:11547-11554.
    • (1994) J Biol Chem , vol.269 , pp. 11547-11554
    • Jenkins, G.H.1    Fisette, P.L.2    Anderson, R.A.3
  • 66
    • 0037168590 scopus 로고    scopus 로고
    • Delayed reentry of recycling vesicles into the fusion-competent synaptic vesicle pool in synaptojanin 1 knockout mice
    • Kim WT, Chang S, Daniell L, Cremona O, Di Paolo G, De Camilli P. 2002. Delayed reentry of recycling vesicles into the fusion-competent synaptic vesicle pool in synaptojanin 1 knockout mice. Proc Natl Acad Sci USA 99:17143-17148.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 17143-17148
    • Kim, W.T.1    Chang, S.2    Daniell, L.3    Cremona, O.4    Di Paolo, G.5    De Camilli, P.6
  • 68
    • 3342965153 scopus 로고    scopus 로고
    • The lipid binding pleckstrin homology domain in UNC-104 kinesin is necessary for synaptic vesicle transport in C. elegans
    • Klopfenstein DR, Vale RD. 2004. The lipid binding pleckstrin homology domain in UNC-104 kinesin is necessary for synaptic vesicle transport in C. elegans. Mol Biol Cell 15:3729-3739.
    • (2004) Mol Biol Cell , vol.15 , pp. 3729-3739
    • Klopfenstein, D.R.1    Vale, R.D.2
  • 69
    • 0038825177 scopus 로고    scopus 로고
    • ARF6 stimulates clathrin/AP-2 recruitment to synaptic membranes by activating phosphatidylinositol phosphate kinase type Iγ
    • Krauss M, Kinuta M, Wenk MR, De Camilli P, Takei K, Haucke V. 2003. ARF6 stimulates clathrin/AP-2 recruitment to synaptic membranes by activating phosphatidylinositol phosphate kinase type Iγ. J Cell Biol 162:113-124.
    • (2003) J Cell Biol , vol.162 , pp. 113-124
    • Krauss, M.1    Kinuta, M.2    Wenk, M.R.3    De Camilli, P.4    Takei, K.5    Haucke, V.6
  • 70
    • 0033213254 scopus 로고    scopus 로고
    • Facilitation of synaptic transmission by EGL-30 Gqα and EGL-8 PLCβ: DAG binding to UNC-13 is required to stimulate acetylcholine release
    • Lackner MR, Nurrish SJ, Kaplan JM. 1999. Facilitation of synaptic transmission by EGL-30 Gqα and EGL-8 PLCβ: DAG binding to UNC-13 is required to stimulate acetylcholine release. Neuron 24:335-346.
    • (1999) Neuron , vol.24 , pp. 335-346
    • Lackner, M.R.1    Nurrish, S.J.2    Kaplan, J.M.3
  • 71
  • 73
    • 33645078650 scopus 로고    scopus 로고
    • Regulation of membrane traffic by phosphoinositide 3-kinases
    • Lindmo K, Stenmark H. 2006. Regulation of membrane traffic by phosphoinositide 3-kinases. J Cell Sci 119:605-614.
    • (2006) J Cell Sci , vol.119 , pp. 605-614
    • Lindmo, K.1    Stenmark, H.2
  • 74
    • 0037038412 scopus 로고    scopus 로고
    • Type Iγ phosphatidylinositol phosphate kinase targets and regulates focal adhesions
    • Ling K, Doughman RL, Firestone AJ, Bunce MW, Anderson RA. 2002. Type Iγ phosphatidylinositol phosphate kinase targets and regulates focal adhesions. Nature 420:89-93.
    • (2002) Nature , vol.420 , pp. 89-93
    • Ling, K.1    Doughman, R.L.2    Firestone, A.J.3    Bunce, M.W.4    Anderson, R.A.5
  • 75
    • 0032478796 scopus 로고    scopus 로고
    • 2 to calcium-dependent activator protein for secretion (CAPS), a potential phosphoinositide effector protein for regulated exocytosis
    • 2 to calcium-dependent activator protein for secretion (CAPS), a potential phosphoinositide effector protein for regulated exocytosis. J Biol Chem 273:8337-8343.
    • (1998) J Biol Chem , vol.273 , pp. 8337-8343
    • Loyet, K.M.1    Kowalchyk, J.A.2    Chaudhary, A.3    Chen, J.4    Prestwich, G.D.5    Martin, T.F.6
  • 76
    • 28444477387 scopus 로고    scopus 로고
    • Plasma membrane phosphoinositide organization by protein electrostatics
    • McLaughlin S, Murray D. 2005. Plasma membrane phosphoinositide organization by protein electrostatics. Nature 438:605-611.
    • (2005) Nature , vol.438 , pp. 605-611
    • McLaughlin, S.1    Murray, D.2
  • 78
    • 0034663849 scopus 로고    scopus 로고
    • Binding kinetics and ligand specificity for the interactions of the C2B domain of synaptogmin II with inositol polyphosphates and phosphoinositides
    • Mehrotra B, Myszka DG, Prestwich GD. 2000. Binding kinetics and ligand specificity for the interactions of the C2B domain of synaptogmin II with inositol polyphosphates and phosphoinositides. Biochemistry 39:9679-9686.
    • (2000) Biochemistry , vol.39 , pp. 9679-9686
    • Mehrotra, B.1    Myszka, D.G.2    Prestwich, G.D.3
  • 80
    • 0013378634 scopus 로고
    • Inositol lipids and their role in receptor function: History and general principles
    • Putney JWJ, editor, New York: Alan R Liss. pp
    • Michell RH. 1986. Inositol lipids and their role in receptor function: History and general principles. In: Putney JWJ, editor. Phosphoinositides and Receptor Mechanisms. New York: Alan R Liss. pp 1-24.
    • (1986) Phosphoinositides and Receptor Mechanisms , pp. 1-24
    • Michell, R.H.1
  • 81
    • 30944461203 scopus 로고    scopus 로고
    • Phosphatidylinositol 3, 5-bisphosphate: Metabolism and cellular functions
    • Michell RH, Heath VL, Lemmon MA, Dove SK. 2006. Phosphatidylinositol 3, 5-bisphosphate: Metabolism and cellular functions. Trends Biochem Sci 31:52-63.
    • (2006) Trends Biochem Sci , vol.31 , pp. 52-63
    • Michell, R.H.1    Heath, V.L.2    Lemmon, M.A.3    Dove, S.K.4
  • 82
    • 0042861412 scopus 로고    scopus 로고
    • Retrograde regulation of synaptic vesicle endocytosis and recycling
    • Micheva KD, Buchanan J, Holz RW, Smith SJ. 2003. Retrograde regulation of synaptic vesicle endocytosis and recycling. Nat Neurosci 6:925-932.
    • (2003) Nat Neurosci , vol.6 , pp. 925-932
    • Micheva, K.D.1    Buchanan, J.2    Holz, R.W.3    Smith, S.J.4
  • 84
    • 0033201511 scopus 로고    scopus 로고
    • Goα and diacylglycerol kinase negatively regulate the Gqα pathway in C. elegans
    • Miller KG, Emerson MD, Rand JB. 1999. Goα and diacylglycerol kinase negatively regulate the Gqα pathway in C. elegans. Neuron 24:323-333.
    • (1999) Neuron , vol.24 , pp. 323-333
    • Miller, K.G.1    Emerson, M.D.2    Rand, J.B.3
  • 87
    • 0026744154 scopus 로고
    • Phosphatidic acid is a specific activator of phosphatidylinositol-4-phosphate kinase
    • Moritz A, De Graan PN, Gispen WH, Wirtz KW. 1992. Phosphatidic acid is a specific activator of phosphatidylinositol-4-phosphate kinase. J Biol Chem 267:7207-7210.
    • (1992) J Biol Chem , vol.267 , pp. 7207-7210
    • Moritz, A.1    De Graan, P.N.2    Gispen, W.H.3    Wirtz, K.W.4
  • 88
    • 0142122093 scopus 로고    scopus 로고
    • Visualizing phosphoinositide signalling in single neurons gets a green light
    • Nahorski SR, Young KW, John Challiss RA, Nash MS. 2003. Visualizing phosphoinositide signalling in single neurons gets a green light. Trends Neurosci 26:444-452.
    • (2003) Trends Neurosci , vol.26 , pp. 444-452
    • Nahorski, S.R.1    Young, K.W.2    John Challiss, R.A.3    Nash, M.S.4
  • 90
    • 0034735785 scopus 로고    scopus 로고
    • Calcium stores regulate the polarity and input specificity of synaptic modification
    • Nishiyama M, Hong K, Mikoshiba K, Poo MM, Kato K. 2000. Calcium stores regulate the polarity and input specificity of synaptic modification. Nature 408:584-588.
    • (2000) Nature , vol.408 , pp. 584-588
    • Nishiyama, M.1    Hong, K.2    Mikoshiba, K.3    Poo, M.M.4    Kato, K.5
  • 91
    • 0033198830 scopus 로고    scopus 로고
    • 0 decreases the abundance of UNC-13 at release sites
    • 0 decreases the abundance of UNC-13 at release sites. Neuron 24:231-242.
    • (1999) Neuron , vol.24 , pp. 231-242
    • Nurrish, S.1    Segalat, L.2    Kaplan, J.M.3
  • 92
    • 0031465172 scopus 로고    scopus 로고
    • Mints, Munc18-interacting proteins in synaptic vesicle exocytosis
    • Okamoto M, Sudhof TC. 1997. Mints, Munc18-interacting proteins in synaptic vesicle exocytosis. J Biol Chem 272:31459-31464.
    • (1997) J Biol Chem , vol.272 , pp. 31459-31464
    • Okamoto, M.1    Sudhof, T.C.2
  • 94
    • 0034772748 scopus 로고    scopus 로고
    • Phosphoinositides as key regulators of synaptic function
    • Osborne SL, Meunier FA, Schiavo G. 2001. Phosphoinositides as key regulators of synaptic function. Neuron 32:9-12.
    • (2001) Neuron , vol.32 , pp. 9-12
    • Osborne, S.L.1    Meunier, F.A.2    Schiavo, G.3
  • 95
    • 33746478107 scopus 로고    scopus 로고
    • Phosphoinositide regulation of neuroexocytosis: Adding to the complexity
    • Osborne SL, Wen PJ, Meunier FA. 2006. Phosphoinositide regulation of neuroexocytosis: Adding to the complexity. J Neurochem 98:336-342.
    • (2006) J Neurochem , vol.98 , pp. 336-342
    • Osborne, S.L.1    Wen, P.J.2    Meunier, F.A.3
  • 96
    • 0017802481 scopus 로고
    • The labelling of nerve ending phospholipids in guinea-pig brain in vivo and the effect of electrical stimulation on phosphatidylinositol metabolism in prelabelled synaptosomes
    • Pickard MR, Hawthorne JN. 1978. The labelling of nerve ending phospholipids in guinea-pig brain in vivo and the effect of electrical stimulation on phosphatidylinositol metabolism in prelabelled synaptosomes. J Neurochem 30:145-155.
    • (1978) J Neurochem , vol.30 , pp. 145-155
    • Pickard, M.R.1    Hawthorne, J.N.2
  • 97
    • 0037201953 scopus 로고    scopus 로고
    • The regulation of phospholipase D by inositol phospholipids and small GTPases
    • Powner DJ, Wakelam MJ. 2002. The regulation of phospholipase D by inositol phospholipids and small GTPases. FEBS Lett 531:62-64.
    • (2002) FEBS Lett , vol.531 , pp. 62-64
    • Powner, D.J.1    Wakelam, M.J.2
  • 99
    • 0037458727 scopus 로고    scopus 로고
    • Phosphatidylinositol 4-OH kinase is a downstream target of neuronal calcium sensor-1 in enhancing exocytosis in neuroendocrine cells
    • Rajebhosale M, Greenwood S, Vidugiriene J, Jeromin A, Hilfiker S. 2003. Phosphatidylinositol 4-OH kinase is a downstream target of neuronal calcium sensor-1 in enhancing exocytosis in neuroendocrine cells. J Biol Chem 278:6075-6084.
    • (2003) J Biol Chem , vol.278 , pp. 6075-6084
    • Rajebhosale, M.1    Greenwood, S.2    Vidugiriene, J.3    Jeromin, A.4    Hilfiker, S.5
  • 101
    • 33645917031 scopus 로고    scopus 로고
    • Spatial segregation of neuronal calcium signals encodes different forms of LTP in rat hippocampus
    • Raymond CR, Redman SJ. 2006. Spatial segregation of neuronal calcium signals encodes different forms of LTP in rat hippocampus. J Physiol 570:97-111.
    • (2006) J Physiol , vol.570 , pp. 97-111
    • Raymond, C.R.1    Redman, S.J.2
  • 104
    • 2942689878 scopus 로고    scopus 로고
    • Effects of wortmannin and latrunculin A on slow endocytosis at the frog neuromuscular junction
    • Richards DA, Rizzoli SO, Betz WJ. 2004. Effects of wortmannin and latrunculin A on slow endocytosis at the frog neuromuscular junction. J Physiol 557:77-91.
    • (2004) J Physiol , vol.557 , pp. 77-91
    • Richards, D.A.1    Rizzoli, S.O.2    Betz, W.J.3
  • 105
    • 0037115043 scopus 로고    scopus 로고
    • Effects of 2-(4-morpholinyl)-8-phenyl-4H-1- benzopyran-4-one on synaptic vesicle cycling at the frog neuromuscular junction
    • Rizzoli SO, Betz WJ. 2002. Effects of 2-(4-morpholinyl)-8-phenyl-4H-1- benzopyran-4-one on synaptic vesicle cycling at the frog neuromuscular junction. J Neurosci 22:10680-10689.
    • (2002) J Neurosci , vol.22 , pp. 10680-10689
    • Rizzoli, S.O.1    Betz, W.J.2
  • 106
    • 0037157830 scopus 로고    scopus 로고
    • 2 binding site within μ2-adaptin regulates clathrin-mediated endocytosis
    • 2 binding site within μ2-adaptin regulates clathrin-mediated endocytosis. J Cell Biol 158:209-214.
    • (2002) J Cell Biol , vol.158 , pp. 209-214
    • Rohde, G.1    Wenzel, D.2    Haucke, V.3
  • 107
    • 13244275403 scopus 로고    scopus 로고
    • Lipid regulation of the synaptic vesicle cycle
    • Rohrbough J, Broadie K. 2005. Lipid regulation of the synaptic vesicle cycle. Nat Rev Neurosci 6:139-150.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 139-150
    • Rohrbough, J.1    Broadie, K.2
  • 109
    • 0036580702 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase is required for the expression but not for the induction or the maintenance of long-term potentiation in the hippocampal CA1 region
    • Sanna PP, Cammalleri M, Berton F, Simpson C, Lutjens R, Bloom FE, Francesconi W. 2002. Phosphatidylinositol 3-kinase is required for the expression but not for the induction or the maintenance of long-term potentiation in the hippocampal CA1 region. J Neurosci 22:3359-3365.
    • (2002) J Neurosci , vol.22 , pp. 3359-3365
    • Sanna, P.P.1    Cammalleri, M.2    Berton, F.3    Simpson, C.4    Lutjens, R.5    Bloom, F.E.6    Francesconi, W.7
  • 111
    • 0029825831 scopus 로고    scopus 로고
    • Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin
    • Schiavo G, Gu QM, Prestwich GD, Sollner TH, Rothman JE. 1996. Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin. Proc Natl Acad Sci USA 93:13327-13332.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 13327-13332
    • Schiavo, G.1    Gu, Q.M.2    Prestwich, G.D.3    Sollner, T.H.4    Rothman, J.E.5
  • 116
    • 0037107493 scopus 로고    scopus 로고
    • Neuronal calcium sensor 1 and phosphatidylinositol 4-OH kinase β interact in neuronal cells and are translocated to membranes during nucleotide-evoked exocytosis
    • Taverna E, Francolini M, Jeromin A, Hilfiker S, Roder J, Rosa P. 2002. Neuronal calcium sensor 1 and phosphatidylinositol 4-OH kinase β interact in neuronal cells and are translocated to membranes during nucleotide-evoked exocytosis. J Cell Sci 115:3909-3922.
    • (2002) J Cell Sci , vol.115 , pp. 3909-3922
    • Taverna, E.1    Francolini, M.2    Jeromin, A.3    Hilfiker, S.4    Roder, J.5    Rosa, P.6
  • 118
    • 0033545698 scopus 로고    scopus 로고
    • Importance of the pleckstrin homology domain of dynamin in clathrin-mediated endocytosis
    • Vallis Y, Wigge P, Marks B, Evans PR, McMahon HT. 1999 Importance of the pleckstrin homology domain of dynamin in clathrin-mediated endocytosis. Curr Biol 9:257-260.
    • (1999) Curr Biol , vol.9 , pp. 257-260
    • Vallis, Y.1    Wigge, P.2    Marks, B.3    Evans, P.R.4    McMahon, H.T.5
  • 120
    • 0037022127 scopus 로고    scopus 로고
    • Essential role of type Iα phosphatidylinositol 4-phosphate 5-kinase in neurite remodeling
    • van Horck FP, Lavazais E, Eickholt BJ, Moolenaar WH, Divecha N. 2002. Essential role of type Iα phosphatidylinositol 4-phosphate 5-kinase in neurite remodeling. Curr Biol 12:241-245.
    • (2002) Curr Biol , vol.12 , pp. 241-245
    • van Horck, F.P.1    Lavazais, E.2    Eickholt, B.J.3    Moolenaar, W.H.4    Divecha, N.5
  • 121
    • 0037172972 scopus 로고    scopus 로고
    • Varoqueaux F, Sigler A, Rhee JS, Brose N, Enk C, Reim K, Rosenmund C. 2002. Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming. Proc Natl Acad Sci USA 99:9037-9042.
    • Varoqueaux F, Sigler A, Rhee JS, Brose N, Enk C, Reim K, Rosenmund C. 2002. Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming. Proc Natl Acad Sci USA 99:9037-9042.
  • 123
    • 33646915714 scopus 로고    scopus 로고
    • Legionella pneumophila exploits PI(4)P to anchor secreted effector proteins to the replicative vacuole
    • Weber SS, Ragaz C, Reus K, Nyfeler Y, Hilbi H. 2006. Legionella pneumophila exploits PI(4)P to anchor secreted effector proteins to the replicative vacuole. PLoS Pathog 2:e46.
    • (2006) PLoS Pathog , vol.2
    • Weber, S.S.1    Ragaz, C.2    Reus, K.3    Nyfeler, Y.4    Hilbi, H.5
  • 124
    • 15444363818 scopus 로고    scopus 로고
    • Distinct Golgi populations of phosphatidylinositol 4-phosphate regulated by phosphatidylinositol 4-kinases
    • Weixel KM, Blumental-Perry A, Watkins SC, Aridor M, Weisz OA. 2005. Distinct Golgi populations of phosphatidylinositol 4-phosphate regulated by phosphatidylinositol 4-kinases. J Biol Chem 280:10501-10508.
    • (2005) J Biol Chem , vol.280 , pp. 10501-10508
    • Weixel, K.M.1    Blumental-Perry, A.2    Watkins, S.C.3    Aridor, M.4    Weisz, O.A.5
  • 125
    • 2942623783 scopus 로고    scopus 로고
    • Protein-lipid interactions and phosphoinositide metabolism in membrane traffic: Insights from vesicle recycling in nerve terminals
    • Wenk MR, De Camilli P. 2004. Protein-lipid interactions and phosphoinositide metabolism in membrane traffic: Insights from vesicle recycling in nerve terminals. Proc Natl Acad Sci USA 101:8262-8269.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 8262-8269
    • Wenk, M.R.1    De Camilli, P.2
  • 127
    • 0029966103 scopus 로고    scopus 로고
    • Chromaffin granule-associated phosphatidylinositol 4-kinase activity is required for stimulated secretion
    • Wiedemann C, Schafer T, Burger MM. 1996. Chromaffin granule-associated phosphatidylinositol 4-kinase activity is required for stimulated secretion. EMBO J 15:2094-2101.
    • (1996) EMBO J , vol.15 , pp. 2094-2101
    • Wiedemann, C.1    Schafer, T.2    Burger, M.M.3
  • 128
    • 0032146218 scopus 로고    scopus 로고
    • An essential role for a small synaptic vesicle-associated phosphatidylinositol 4-kinase in neurotransmitter release
    • Wiedemann C, Schafer T, Burger MM, Sihra TS. 1998. An essential role for a small synaptic vesicle-associated phosphatidylinositol 4-kinase in neurotransmitter release. J Neurosci 18:5594-5602.
    • (1998) J Neurosci , vol.18 , pp. 5594-5602
    • Wiedemann, C.1    Schafer, T.2    Burger, M.M.3    Sihra, T.S.4
  • 129
    • 0037118050 scopus 로고    scopus 로고
    • A common mechanism of action for three mood-stabilizing drugs
    • Williams RS, Cheng L, Mudge AW, Harwood AJ. 2002. A common mechanism of action for three mood-stabilizing drugs. Nature 417:292-295.
    • (2002) Nature , vol.417 , pp. 292-295
    • Williams, R.S.1    Cheng, L.2    Mudge, A.W.3    Harwood, A.J.4
  • 130
    • 0028032480 scopus 로고
    • Cloning and characterization of a human phosphatidylinositol 4-kinase
    • Wong K, Cantley LC. 1994. Cloning and characterization of a human phosphatidylinositol 4-kinase. J Biol Chem 269:28878-28884.
    • (1994) J Biol Chem , vol.269 , pp. 28878-28884
    • Wong, K.1    Cantley, L.C.2
  • 133
    • 0035955738 scopus 로고    scopus 로고
    • Interaction of neuronal calcium sensor-1 (NCS-1) with phosphatidylinositol 4-kinase β stimulates lipid kinase activity and affects membrane trafficking in COS-7 cells
    • Zhao X, Varnai P, Tuymetova G, Balla A, Toth ZE, Oker-Blom C, Roder J, Jeromin A, Balla T. 2001. Interaction of neuronal calcium sensor-1 (NCS-1) with phosphatidylinositol 4-kinase β stimulates lipid kinase activity and affects membrane trafficking in COS-7 cells. J Biol Chem 276:40183-40189.
    • (2001) J Biol Chem , vol.276 , pp. 40183-40189
    • Zhao, X.1    Varnai, P.2    Tuymetova, G.3    Balla, A.4    Toth, Z.E.5    Oker-Blom, C.6    Roder, J.7    Jeromin, A.8    Balla, T.9
  • 134
    • 3042693930 scopus 로고    scopus 로고
    • ADP-ribosylation factor6 regulates both [3H]-noradrenaline and [14C]-glutamate exocytosis through phosphatidylinositol 4,5-bisphosphate
    • Zheng Q, Bobich JA. 2004. ADP-ribosylation factor6 regulates both [3H]-noradrenaline and [14C]-glutamate exocytosis through phosphatidylinositol 4,5-bisphosphate. Neurochem Int 45:633-640.
    • (2004) Neurochem Int , vol.45 , pp. 633-640
    • Zheng, Q.1    Bobich, J.A.2
  • 137
    • 27744467849 scopus 로고    scopus 로고
    • Molecular cloning and characterization of PLCη2
    • Zhou Y, Wing MR, Sondek J, Harden TK. 2005. Molecular cloning and characterization of PLCη2. Biochem J 391:667-676.
    • (2005) Biochem J , vol.391 , pp. 667-676
    • Zhou, Y.1    Wing, M.R.2    Sondek, J.3    Harden, T.K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.