Type Iγ phosphatidylinositol phosphate kinase targets and regulates focal adhesions

Nature

Volumn 420, Issue 6911, 2002, Pages 89-93

  Ling, Kun ^a   Doughman, Renee L ^a   Firestone, Ari J ^a   Bunce, Matthew W ^a   Anderson, Richard A ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYMES; LIPIDS;

FOCAL ADHESIONS;

IMMUNOLOGY;

ACTIN; INTEGRIN; PHOSPHATIDYLINOSITOL 4 PHOSPHATE KINASE; PHOSPHATIDYLINOSITOL 4 PHOSPHATE KINASE TYPE 1GAMMA; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; TALIN; UNCLASSIFIED DRUG; VINCULIN;

BIOCHEMISTRY; IMMUNE RESPONSE;

ARTICLE; CELL ADHESION; CELL MIGRATION; CELL STRUCTURE; CELL SURVIVAL; DEVELOPMENT; EXTRACELLULAR MATRIX; FOCAL ADHESION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; METASTASIS; PRIORITY JOURNAL; WOUND HEALING;

ACTINS; ANIMALS; BINDING SITES; CELL LINE; CELL MEMBRANE; FOCAL ADHESION KINASE 1; FOCAL ADHESION PROTEIN-TYROSINE KINASES; FOCAL ADHESIONS; HUMANS; INTEGRIN BETA CHAINS; ISOENZYMES; MICE; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN BINDING; PROTEIN-TYROSINE KINASES; RATS; RECOMBINANT FUSION PROTEINS; TALIN; VINCULIN;

EID: 0037038412     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature01082     Document Type: Article

References (31)

1. Critchley, D. R. Focal adhesions - the cytoskeleton connection. Curr. Opin. Cell Biol. 12, 133-139 (2000).
2. Burridge, K. & Chrzanowska-Wodnicka, M. Focal adhesions, contractility and signaling. Annu. Rev. Cell Dev. Biol. 12, 463-518 (1996).
3. Schwartz, M. A. & Ginsberg, M. H. Networks and crosstalk: Integrin signalling spreads. Nature Cell Biol. 4, E65-E68 (2002).
4. McNamee, H. P., Ingber, D. E. & Schwartz, M. A. Adhesion to fibronectin stimulates inositol lipid synthesis and enhances PDGF-induced inositol lipid breakdown. J. Cell Biol. 121, 673-678 (1993).
5. Berditchevski, F., Tolias, K. F., Wong, K., Carpenter, C. L. & Hemler, M. E. A novel link between integrins, transmembrane-4 superfamily proteins (CD63 and CD81), and phosphatidylinositol 4-kinase. J. Biol. Chem. 272, 2595-2598 (1997).
6. Chong, L. D., Traynor-Kaplan, A., Bokoch, G. M. & Schwartz, M. A. The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells. Cell 79, 507-513 (1994).
7. Gilmore, A. P. & Burridge, K. Regulation of vinculin binding to talin and actin by phosphatidyl-inositol-4, 5-bisphosphate. Nature 381, 531-535 (1996).
8. Steimle, P. A., Hoffert, J. D., Adey N. B. & Craig, S. W. Polyphosphoinositides inhibit interaction of vinculin with actin filaments. J. Biol. Chem. 274, 18414-18420 (1999).
9. Martel, V. et al. Conformation, localization, and integrin binding of talin depend oil its interaction with phosphoinositides. J. Biol. Chem. 276, 21217-21227 (2001).
10. Janmey, P. A. Phosphoinositides and calcium as regulators of cellular actin assembly and disassembly. Annu. Rev. Physiol. 56, 169-191 (1994).
11. Anderson, R. A., Boronenkov, I. V., Doughman, S. D., Kunz, J. & Loijens, J. C. Phosphatidylinositol phosphate kinases, a multifaceted family of signaling enzymes. J. Biol. Chem. 274, 9907-9910 (1999).
12. Kunz, J. et al. The activation loop of phosphatidylinositol phosphate kinases determines signaling specificity. Mol. Cell 5, 1-11 (2000).
13. Ishihara, H. et al. Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family. J. Biol. Chem. 273, 8741-8748 (1998).
14. Rao, V. D., Misra, S., Boronenkov, I. V., Anderson, R. A. & Hurley, J. H. Structure of type IIβ phosphatidylinositol phosphate kinase: a protein kinase fold flattened for interfacial phosphorylation. Cell 94, 829-839 (1998).
15. Pasquale, E. B., Maher, P. A. & Singer, S. J. Talin is phosphorylated on tyrosine in chicken embryo fibroblasts transformed by Rous sarcoma virus. Proc Natl. Acad. Sci. USA 83, 5507-5511 (1986).
16. DeClue, J. E. & Martin, G. S. Phosphorylation of talin at tyrosine in Rous sarcoma virus-transformed cells. Mol. Cell Biol. 7, 371-378 (1987).
17. Calderwood, D. A. et al. The Talin head domain binds to integrin β subunit cytoplasmic tails and regulates integrin activation. J. Biol. Chem. 274, 28071-28074 (1999).
18. Rees, D. J., Ades, S. E., Singer, S. J. & Hynes, R. O. Sequence and domain structure of talin. Nature 347, 685-689 (1990).
19. Chisti, A. H. et al. The FERM domain: A unique module involved in the linkage of cytoplasmic proteins to the membrane. Trends Biochem. Sci. 23, 281-282 (1998).
20. Calderwood, D. A. et al. The phosphotyrosine binding (PTB)-like domain of talin activates integrins. J. Biol. Chem. 277, 21749-21758 (2002).
21. Cary, L. A. & Guan, J. L. Focal adhesion kinase in integrin-mediated signaling. Front. Biosci. 4, D102-D113 (1999).
22. Rodriquez-Fernandez, J. L. & Rozengurt, E. Bombesin, vasopressin, lysophosphatidic acid, and sphingosylphosphorylcholine induce focal adhesion kinase activation in intact Swiss 3T3 cells. J. Biol. Chem. 273, 19321-19328 (1998).
23. Chan, P. Y., Kanner, S. B., Whitney, G. & Aruffo, A. A transmembrane-anchored chimeric focal adhesion kinase is constitutively activated and phosphorylated at tyrosine residues identical to pp125FAK. J. Biol. Chem. 269, 20567-20574 (1994).
24. Anderson, R. A. & Marchesi, V. T. Regulation of the association of membrane skeletal protein 4.1 with glycophorin by a polyphosphoinositide. Nature 318, 295-298 (1985).
25. Hirao, M. et al. Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: Possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway. J. Cell Biol. 135, 37-51 (1996).
26. Honda, A. et al. Phosphatidylinositol 4-phosphate 5-kinase α is a downstream effector of the small G protein ARF6 in membrane ruffle formation. Cell 99, 521-532 (1999).
27. Jenkins, G. H., Fiselte, P. L. & Anderson, R. A. Type I phosphatidylinositol 4-phosphate kinase isoforms are specifically stimulated by phosphatidic acid. J. Biol. Chem. 269, 11547-11554 (1994).
28. Kam, Y. & Exton, J. H. Phospholipase D activity is required for actin stress fiber formation in fibroblasts. Mol. Cell Biol. 21, 4055-4066 (2001).
29. James, P., Halladay, J. & Craig, E. A. Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics 144, 1425-1436 (1996).
30. Loijens, J. C. & Anderson, R. A. Type I phosphatidylinositol-4-phosphate 5-kinase are distinct members of this novel lipid kinase family. J. Biol. Chem. 271, 32937-32943 (1996).
31. Zhang, X. L. et al. Phosphatidylinositol-4-phosphate 5-kinase isozymes catalyze the synthesis of 3-phosphate-containing phosphatidylinositol signaling molecules. J. Biol. Chem. 272, 17756-17761 (1997).