N,N,N-trimethylchitosan chloride as a gene vector: Synthesis and application

Macromolecular Bioscience

Volumn 7, Issue 6, 2007, Pages 855-863

  Mao, Zhengwei ^a   Lie, Ma ^a   Jiang, Yan ^a   Yan, Ming ^b   Gao, Changyou ^a   Shen, Jiacong ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

Biological applications of polymers; Functionalization of polymers; Gene delivery; N,N,N trimethylchitosan; Non viral vector; Transfection

Indexed keywords

FUNCTIONALIZATION; GENE DELIVERY; NONVIRAL VECTORS;

BIOCOMPATIBILITY; BIOPOLYMERS; MEDICAL APPLICATIONS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SYNTHESIS (CHEMICAL); TOXICITY;

POLYSACCHARIDES;

CHITOSAN DERIVATIVE; N,N,N TRIMETHYLCHITOSAN CHLORIDE; NANOPARTICLE; UNCLASSIFIED DRUG;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; ENDOCYTOSIS; GENE VECTOR; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PARTICLE SIZE; PHYSICAL CHEMISTRY; PROTON NUCLEAR MAGNETIC RESONANCE;

CELL LINE; CHITOSAN; DNA; GENETIC VECTORS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; PARTICLE SIZE; TETRAZOLIUM SALTS; THIAZOLES; TOXICITY TESTS; TRANSFECTION;

EID: 34547688544     PISSN: 16165187     EISSN: 16165195     Source Type: Journal    
DOI: 10.1002/mabi.200700015     Document Type: Article

References (35)

1. W. T. Godbey, A. G. Mikos, J. Controlled Release 2001, 72, 115.
2. X. Gao, L. Huang, Gene Ther. 1995, 2, 710.
3. S. C. De Smedt, J. Demeester, W. E. Hennink, Pharm. Res. 2000, 17, 113.
4. M. C. Garnett, Crit. Rev. Ther. Drug Carrier Syst. 1999, 16, 147.
5. K. Minagawa, Y. Matzusawa, K. Yoshikawa, M. Matsumoto, M. Doi, FEBS Lett. 1991, 295, 67.
6. M. Hashimoto, M. Morimoto, H. Saimoto, Y. Shigemasa, T. Sato, Bioconjugate Chem. 2006, 17, 309.
7. G. Borchard, Adv. Drug Delivery Rev. 2001, 52, 145.
8. M. N. V. R. Kumar, R. A. A. Muzzarelli, C. Muzzarelli, H. Sashiwa, A. J. Domb, Chem. Rev. 2004, 104, 6017.
9. H. Q. Mao, K. Roy, V. L. Troung-Le, K. A. Jane, K. Y. Lin, Y. Wang, J. T. August, K. W. Leong, J. Controlled Release 2001, 70, 399.
10. A. F. Kotze, H. L. Luessen, A. G. de Boer, J. C. Verhoef, H. E. Junginger, Eur. J. Pharm. Sci. 1998, 7, 145.
11. A. B. Sieval, M. Thanou, A. F. Kotze, J. E. Verhoef, J. Brussee, H. E. Junginger, Carbohydr. Polym. 1998, 36, 157.
12. I. K. Park, Y. H. Park, B. A. Shin, E. S. Choi, Y. R. Kim, T. Akaike, C. S. Cho, J. Controlled Release 2000, 69, 97.
13. I. K. Park, T. H. Kim, Y. H. Park, B. A. Shin, E. S. Choi, E. H. Chowdhury, T. Akiake, C. S. Cho, J. Controlled Release 2001, 76, 349.
14. I. K. Park, J. E. Ihm, Y. H. Park, Y. J. Choi, S. I. Kim, W. J. Kim, T. Akiake, C. S. Cho, J. Controlled Release 2003, 86, 349.
15. J. Zabner, A. J. Fasbender, T. Moninger, K. A. Poellinger, M. J. Welsh, J. Biol. Chem. 1995, 270, 18997.
16. T. Segura, L. D. Shea, Annu. Rev. Mater. Res. 2001, 31, 25.
17. M. Koping-Hoggard, K. M. Varum, P. Artursson, Gene Ther. 2001, 8, 1108.
18. P. Erbacher, S. Zou, T. Bettinger, A. M. Steffan, J. S. Remy, Pharm. Res. 1998, 15, 1332.
19. S. Gao, J. Chen, X. Xu, Z. Ding, Y. H. Yang, Z. Hua, J. Zhang, Int. J. Pharm. 2003, 255, 57.
20. T. Sato, T. Ishii, Y. Okahata, Biomaterials 2001, 22, 2075.
21. E. Wagner, J. Controlled Release 1998, 53, 155.
22. T. Ishii, Y. Okahata, T. Sato, Biochim. Biophys. Acta 2001, 1514, 51.
23. A. F. Kotze, H. L. Luessen, B. J. deLeeuw, B. G. deBoer, J. C. Verhoef, H. E. Junginger, Pharm. Res. 1997, 14, 1197.
24. M. Thanou, B. I. Florea, M. Geldof, H. E. Junginger, G. Borchard, Biomaterials 2002, 23, 153.
25. S. M. Van der Merwe, J. C. Verhoef, J. H. Verheijden, A. F. Kotze, H. E. Junginger, Eur. J. Pharm. Biopharm. 2004, 58, 225.
26. S. R. Mao, X. T. Shuai, F. Unger, M. Wittmar, X. L. Xie, T. Kissel, Biomaterials 2005, 26, 6343.
27. T. Kean, S. Roth, M. Thanou, J. Controlled Release 2005, 103, 643.
28. H. Q. Mao, K. Roy, V. L. Troung-Le, K. A. Janes, K. Y. Lin, Y. Wang, J. T. August, K. W. Leong, J. Controlled Release 2001, 70, 399.
29. Z. W. Mao, L. Ma, J. Zhou, C. Y. Gao, J.C. Shen, Bioconj. Chem. 2005, 16, 1316.
30. T. Ishii, Y. Okahata, T. Sato, Chem. Lett. 2000, 29, 386.
31. W. G. Liu, X. Zhang, S. J. Sun, G. J. Sun, K. D. Yao, D. C. Liang, G. Guo, J. Y. Zhang, Bioconj. Chem. 2003, 14, 782.
32. D. Lechardeur, A. S. Verkman, G. L. Lukacus, Adv. Drug Delivery Rev. 2005, 57, 755.
33. P. M. Quinton, C. W. Phillpot, J. Cell. Biol. 1973, 56, 787.
34. D. M. Morgan, V. L. Larvin, J. L. Pearson, J. Cell. Sci. 1989, 94, 553.
35. P. Artursson, T. Lindmark, S. S. Davis, L. Illum, Pharm. Res. 1994, 11, 1358.