S-adenosyl-L-methionine-dependent methyl transfer: Observable precatalytic intermediates during DNA cytosine methylation

Biochemistry

Volumn 46, Issue 30, 2007, Pages 8766-8775

  Youngblood, Ben ^a   Shieh, Fa Kuen ^a   Buller, Fabian ^a   Bullock, Tim ^a   Reich, Norbert O ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; DNA; METHYLATION; MOLECULAR STRUCTURE; MUTAGENESIS;

BACTERIAL ENZYMES; BIOLOGICAL PATHWAYS; CYTOSINE METHYLATION;

ENZYMES;

DNA (CYTOSINE 5) METHYLTRANSFERASE; S ADENOSYLMETHIONINE;

AB INITIO CALCULATION; ARTICLE; CALCULATION; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME MECHANISM; ENZYME STRUCTURE; HYDROGEN BOND; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; PRIORITY JOURNAL; QUANTUM MECHANICS; STRUCTURE ANALYSIS; VALIDATION PROCESS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BINDING SITES; CRYSTALLIZATION; CYTOSINE; DNA METHYLATION; KINETICS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MUTAGENESIS, INSERTIONAL; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; S-ADENOSYLMETHIONINE; SITE-SPECIFIC DNA METHYLTRANSFERASE (CYTOSINE-SPECIFIC); SUBSTRATE SPECIFICITY; WATER;

BACTERIA (MICROORGANISMS);

EID: 34547618276     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi7005948     Document Type: Article

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