Advances in sepsis research derived from animal models

International Journal of Medical Microbiology

Volumn 297, Issue 5, 2007, Pages 393-400

  Männel, Daniela N ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

Cecal ligation and puncture (CLP); Inflammation; Lipopolysaccharide (LPS); Tolerance; Toll like receptors (TLR); Tumor necrosis factor (TNF)

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CYTOKINE; LIPID A; LIPOPOLYSACCHARIDE BINDING PROTEIN; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR;

ADAPTIVE IMMUNITY; BACTERIAL INFECTION; CELL ACTIVATION; CYTOKINE PRODUCTION; DENDRITIC CELL; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HELPER CELL; HOMEOSTASIS; IMMUNOREGULATION; INFLAMMATION; INNATE IMMUNITY; NONHUMAN; PERITONITIS; SEPSIS; SHORT SURVEY;

EID: 34547518473     PISSN: 14384221     EISSN: 16180607     Source Type: Journal    
DOI: 10.1016/j.ijmm.2007.03.005     Document Type: Short Survey

References (48)

1. Akira S., and Takeda K. Toll-like receptor signalling. Nat. Rev. Immunol. 4 (2004) 499-511
2. Alexander C., and Rietschel E.T. Bacterial lipopolysaccharides and innate immunity. J. Endotoxin Res. 7 (2001) 167-202
3. Beutler B., Milsark I.W., and Cerami A.C. Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin. Science 229 (1985) 869-871
4. Beutler B., Jiang Z., Georgel P., Crozat K., Croker B., Rutschmann S., Du X., and Hoebe K. Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large. Annu. Rev. Immunol. 24 (2006) 353-389
5. Bohn E., and Autenrieth I.B. IL-12 is essential for resistance against Yersinia enterocolitica by triggering IFN-gamma production in NK cells and CD4+ T cells. J. Immunol. 156 (1996) 1458-1468
6. Burns K., Janssens S., Brissoni B., Olivos N., Beyaert R., and Tschopp J. Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4. J. Exp. Med. 197 (2003) 263-268
7. Chakir H., Wang H., Lefebvre D.E., Webb J., and Scott F.W. T-bet/GATA-3 ratio as a measure of the Th1/Th2 cytokine profile in mixed cell populations: predominant role of GATA-3. J. Immunol. Methods 278 (2003) 157-169
8. Cross A.S. Endotoxin tolerance - current concepts in historical perspective. J. Endotoxin Res. 8 (2002) 83-98
9. Deiters U., Gumenscheimer M., Galanos C., and Muhlradt P.F. Toll-like receptor 2- and 6-mediated stimulation by macrophage-activating lipopeptide 2 induces lipopolysaccharide (LPS) cross tolerance in mice, which results in protection from tumor necrosis factor alpha but in only partial protection from lethal LPS doses. Infect. Immun. 71 (2003) 4456-4462
10. Echtenacher B., Falk W., Männel D.N., and Krammer P.H. Requirement of endogenous tumor necrosis factor/cachectin for recovery from experimental peritonitis. J. Immunol. 145 (1990) 3762-3766
11. Echtenacher B., Freudenberg M.A., Jack R.S., and Männel D.N. Differences in innate defense mechanisms in endotoxemia and polymicrobial septic peritonitis. Infect. Immun. 69 (2001) 7271-7276
12. Echtenacher B., Weigl K., Lehn N., and Männel D.N. Tumor necrosis factor-dependent adhesions as a major protective mechanism early in septic peritonitis in mice. Infect. Immun. 69 (2001) 3550-3555
13. Echtenacher B., Urbaschek R., Weigl K., Freudenberg M.A., and Männel D.N. Treatment of experimental sepsis-induced immunoparalysis with TNF. Immunobiology 208 (2003) 381-389
14. Feizi T. Carbohydrate-mediated recognition systems in innate immunity. Immunol. Rev. 173 (2000) 79-88
15. Ferlito M., Romanenko O.G., Ashton S., Squadrito F., Halushka P.V., and Cook J.A. Effect of cross-tolerance between endotoxin and TNF-alpha or IL-1beta on cellular signaling and mediator production. J. Leukoc. Biol. 70 (2001) 821-829
16. Freudenberg M.A., and Galanos C. Induction of tolerance to lipopolysaccharide (LPS)-D-galactosamine lethality by pretreatment with LPS is mediated by macrophages. Infect. Immun. 56 (1988) 1352-1357
17. Freudenberg M.A., Kopf M., and Galanos C. Lipopolysaccharide-sensitivity of interferon-gamma-receptor deficient mice. J. Endotoxin Res. 3 (1996) 291-298
18. Fujita T., Matsushita M., and Endo Y. The lectin-complement pathway - its role in innate immunity and evolution. Immunol. Rev. 198 (2004) 185-202
19. Gumenscheimer M., Mitov I., Galanos C., and Freudenberg M.A. Beneficial or deleterious effects of a preexisting hypersensitivity to bacterial components on the course and outcome of infection. Infect. Immun. 70 (2002) 5596-5603
20. Hawlisch H., and Köhl J. Complement and Toll-like receptors: key regulators of adaptive immune responses. Mol. Immunol. 43 (2006) 13-21
21. Heine H., Rietschel E.T., and Ulmer A.J. The biology of endotoxin. Mol. Biotechnol. 19 (2001) 279-296
22. Heinrich J.M., Bernheiden M., Minigo G., Yang K.K., Schütt C., Männel D.N., and Jack R.S. The essential role of lipopolysaccharide-binding protein in protection of mice against a peritoneal Salmonella infection involves the rapid induction of an inflammatory response. J. Immunol. 167 (2001) 1624-1628
23. Janeway Jr. C.A., and Medzhitov R. Innate immune recognition. Annu. Rev. Immunol. 20 (2002) 197-216
24. Kaisho T., and Akira S. Toll-like receptor function and signaling. J. Allergy Clin. Immunol. 117 (2006) 979-987
25. Katschinski T., Galanos C., Coumbos A., and Freudenberg M.A. Gamma interferon mediates Propionibacterium acnes-induced hypersensitivity to lipopolysaccharide in mice. Infect. Immun. 60 (1992) 1994-2001
26. Kinjyo I., Hanada T., Inagaki-Ohara K., Mori H., Aki D., Ohishi M., Yoshida H., Kubo M., and Yoshimura A. SOCS1/JAB is a negative regulator of LPS-induced macrophage activation. Immunity 17 (2002) 583-591
27. Kobayashi K., Hernandez L.D., Galan J.E., Janeway Jr. C.A., Medzhitov R., and Flavell R.A. IRAK-M is a negative regulator of Toll-like receptor signaling. Cell 110 (2002) 191-202
28. Krieg A.M. The role of CpG motifs in innate immunity. Curr. Opin. Immunol. 12 (2000) 35-43
29. Lehner M.D., Ittner J., Bundschuh D.S., van Rooijen N., Wendel A., and Hartung T. Improved innate immunity of endotoxin-tolerant mice increases resistance to Salmonella enterica serovar Typhimurium infection despite attenuated cytokine response. Infect. Immun. 69 (2001) 463-471
30. Liew F.Y., Liu H., and Xu D. A novel negative regulator for IL-1 receptor and Toll-like receptor 4. Immunol. Lett. 96 (2005) 27-31
31. Lu J., Teh C., Kishore U., and Reid K.B. Collectins and ficolins: sugar pattern recognition molecules of the mammalian innate immune system. Biochim. Biophys. Acta 1572 (2002) 387-400
32. Marino M.W., Dunn A., Grail D., Inglese M., Noguchi Y., Richards E., Jungbluth A., Wada H., Moore M., Williamson B., Basu S., and Old L.J. Characterization of tumor necrosis factor-deficient mice. Proc. Natl. Acad. Sci. USA 94 (1997) 8093-8098
33. Martin M.U., and Wesche H. Summary and comparison of the signaling mechanisms of the Toll/interleukin-1 receptor family. Biochim. Biophys. Acta 1592 (2002) 265-280
34. Mercer-Jones M.A., Heinzelmann M., Peyton J.C., Wickel D.J., Cook M., and Cheadle W.G. The pulmonary inflammatory response to experimental fecal peritonitis: relative roles of tumor necrosis factor-alpha and endotoxin. Inflammation 21 (1997) 401-417
35. Meylan E., Tschopp J., and Karin M. Intracellular pattern recognition receptors in the host response. Nature 442 (2006) 39-44
36. Netea M.G., Van der Graaf C., Van der Meer J.W., and Kullberg B.J. Toll-like receptors and the host defense against microbial pathogens: bringing specificity to the innate-immune system. J. Leukoc. Biol. 75 (2004) 749-755
37. Serhan C.N., and Savill J. Resolution of inflammation: the beginning programs the end. Nat. Immunol. 6 (2005) 1191-1197
38. Sterns T., Pollak N., Echtenacher B., and Männel D.N. Divergence of protection induced by bacterial products and sepsis-induced immune suppression. Infect. Immun. 73 (2005) 4905-4912
39. Takeda K., Kaisho T., and Akira S. Toll-like receptors. Annu. Rev. Immunol. 21 (2003) 335-376
40. Trinchieri G. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat. Rev. Immunol. 3 (2003) 133-146
41. Underhill D.M., and Ozinsky A. Toll-like receptors: key mediators of microbe detection. Curr. Opin. Immunol. 14 (2002) 103-110
42. Volk H.D., Reinke P., and Döcke W.D. Clinical aspects: from systemic inflammation to 'immunoparalysis'. Chem. Immunol. 74 (2000) 162-177
43. Wald D., Qin J., Zhao Z., Qian Y., Naramura M., Tian L., Towne J., Sims J.E., Stark G.R., and Li X. SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling. Nat. Immunol. 4 (2003) 920-927
44. Wichterman K.A., Baue A.E., and Chaudry I.H. Sepsis and septic shock - a review of laboratory models and a proposal. J. Surg. Res. 29 (1980) 189-201
45. Wysocka M., Kubin M., Vieira L.Q., Ozmen L., Garotta G., Scott P., and Trinchieri G. Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice. Eur. J. Immunol. 25 (1995) 672-676
46. Zantl N., Uebe A., Neumann B., Wagner H., Siewert J.R., Holzmann B., Heidecke C.D., and Pfeffer K. Essential role of gamma interferon in survival of colon ascendens stent peritonitis, a novel murine model of abdominal sepsis. Infect. Immun. 66 (1998) 2300-2309
47. Zhou P., Sieve M.C., Bennett J., Kwon-Chung K.J., Tewari R.P., Gazzinelli R.T., Sher A., and Seder R.A. IL-12 prevents mortality in mice infected with Histoplasma capsulatum through induction of IFN-gamma. J. Immunol. 155 (1995) 785-795
48. Zisman D.A., Kunkel S.L., Strieter R.M., Gauldie J., Tsai W.C., Bramson J., Wilkowski J.M., Bucknell K.A., and Standiford T.J. Anti-interleukin-12 therapy protects mice in lethal endotoxemia but impairs bacterial clearance in murine Escherichia coli peritoneal sepsis. Shock 8 (1997) 349-356