[18F]FPhEP and [18F]F2PhEP, two new epibatidine-based radioligands: Evaluation for imaging nicotinic acetylcholine receptors in baboon brain

Synapse

Volumn 61, Issue 9, 2007, Pages 764-770

  Valette, Héric ^a   Dollé, Frédéric ^a   Saba, Wadad ^a   Roger, Gaelle ^a   Hinnen, Françoise ^a   Coulon, Christine ^a   Ottaviani, Michele ^a   Syrota, André ^a   Bottlaender, Michel ^a  

^a SERVICE HOSPITALIER FRÉDÉRIC JOLIOT   (France)

Author keywords

Positron emission tomography

Indexed keywords

2 EXO (2' FLUORO 3' PHENYLPYRIDIN 5' YL) 7 AZABICYCLO[2.2.1]HEPTANE F 18; 2 EXO [2' FLUORO 3' (4 FLUOROPHENYL)PYRIDIN 5' YL] 7 AZABICYCLO[2.2.1]HEPTANE F 18; ALPHA4 BETA2 NICOTINIC ANTAGONIST; CYTOSINE; EPIBATIDINE; FLUORINE 18; NICOTINE; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; RADIOLIGAND; UNCLASSIFIED DRUG; 3 (2 AZETIDINYLMETHOXY)PYRIDINE; AZETIDINE DERIVATIVE; FLUORINE; FUSED HETEROCYCLIC RINGS; PYRIDINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BABOON; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG STRUCTURE; NEUROIMAGING; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RADIOACTIVITY; ANIMAL; BINDING COMPETITION; BLOOD; BRAIN; BRAIN LEVEL; CHEMISTRY; COMPUTER ASSISTED DIAGNOSIS; COMPUTER ASSISTED EMISSION TOMOGRAPHY; DOSE RESPONSE; DRUG EFFECT; EVALUATION; HISTOLOGY; METABOLISM; NUCLEAR MAGNETIC RESONANCE IMAGING; PAPIO; SCINTISCANNING; TIME;

ANIMALS; AZETIDINES; BICYCLO COMPOUNDS, HETEROCYCLIC; BINDING, COMPETITIVE; BRAIN; BRAIN CHEMISTRY; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUORINE RADIOISOTOPES; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; PAPIO; PYRIDINES; RECEPTORS, NICOTINIC; TIME FACTORS; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 34547167527     PISSN: 08874476     EISSN: 10982396     Source Type: Journal    
DOI: 10.1002/syn.20426     Document Type: Article

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