Impaired firing and sodium channel function in CA1 hippocampal interneurons after transient cerebral ischemia

Journal of Cerebral Blood Flow and Metabolism

Volumn 27, Issue 8, 2007, Pages 1444-1452

  Zhan, Ren Zhi ^a   Nadler, J Victor ^a   Schwartz Bloom, Rochelle D ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Epilepsy; Excitatory amino acid; Hippocampal ischemia; Ischemic neuronal death; Patch clamp recording

Indexed keywords

PARVALBUMIN; SODIUM CHANNEL;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL NEURAL NETWORK; BRAIN ISCHEMIA; BRAIN SLICE; CAROTID ARTERY OBSTRUCTION; COMMON CAROTID ARTERY; CORPUS STRIATUM; CYTOCHEMISTRY; HIPPOCAMPUS; HYPOTENSION; IMMUNOFLUORESCENCE; IMMUNOREACTIVITY; INTERNEURON; MALE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; RAT STRAIN; REPERFUSION; SODIUM CURRENT; SPRAGUE DAWLEY RAT; VOLTAGE CLAMP;

ACTION POTENTIALS; ANIMALS; BICUCULLINE; BRAIN ISCHEMIA; GABA ANTAGONISTS; HIPPOCAMPUS; INTERNEURONS; MALE; NERVE TISSUE PROTEINS; PARVALBUMINS; PATCH-CLAMP TECHNIQUES; PROTEIN SUBUNITS; PYRAMIDAL CELLS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; SODIUM CHANNELS;

EID: 34547125078     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jcbfm.9600448     Document Type: Article

References (39)

1. Akaike N (1996) Gramicidin perforated patch recording and intracellular chloride activity in excitable cells. Prog Biophys Mol Biol 65:251-64
2. Avignone E, Frenguelli BG, Irving AJ (2005) Differential responses to NMDA receptor activation in rat hippocampal interneurons and pyramidal cells may underlie enhanced pyramidal cell vulnerability. Eur J Neurosci 22:3077-90
3. Baimbridge KG, Celio MR, Rogers JH (1992) Calcium-binding proteins in the nervous system. Trends Neurosci 15:303-8
4. Banasiak KJ, Burenkova O, Haggad GG (2004) Activation of voltage-sensitive sodium channels during oxygen deprivation leads to apoptotic neuronal death. Neuroscience 126:31-44
5. Buhl EH, Halasy K, Somogyi P (1994) Diverse sources of hippocampal unitary inhibitory postsynaptic potentials and the number of synaptic release sites. Nature 368:823-8
6. Ferrer I, Soriano WA, Vidal A, Planas AW (1995) Survival of parvalbumin-immunoreactive neurons in the gerbil hippocampus following transient forebrain ischemia does not depend on HSP-70 protein induction. Brain Res 692:41-6
7. Frahm C, Haupt C, Witte OW (2004) GABA neurons survive focal ischemic injury. Neuroscience 127:341-6
8. Goldin AL, Barchi RL, Caldwell JH, Hofmann F, Howe JR, Hunter JC, Kallen RG, Mandel G, Meisler MH, Netter YB, Noda M, Tamkun MM, Waxman SG, Wood JN, Catterall WA (2000) Nomenclature of voltage-gated sodium channels. Neuron 28:365-8
9. 2 on CA1 neuronal excitability. Am J Physiol 287:C691-7
10. Halasy K, Buhl EH, Lörinczi Z, Tamás G, Somogyi P (1996) Synaptic target selectivity and input of GABAergic basket and bistratified interneurons in the CA1 area of the rat hippocampus. Hippocampus 6:306-29
11. A receptor alpha 1-subunit-immunoreactive interneurons in the gerbil CA1 hippocampus. Hippocampus 7:511-23
12. Johansen FF, Diemer NH (1990) Temporal profile of interneuron and pyramidal cell protein synthesis in rat hippocampus following cerebral ischemia. Acta Neuropathol 81:14-9
13. Johansen FF, Jorgensen MB, Diemer NH (1983) Resistance of hippocampal CA-1 interneurons to 20 min of transient cerebral ischemia in the rat. Acta Neuropathol 61:135-40
14. Johansen FF, Lin CT, Schousboe A, Wu JY (1989) Immunocytochemical investigation of L-glutamic acid decarboxylase in the rat hippocampal formation: the influence of transient cerebral ischemia. J Comp Neurol 281:40-53
15. Katchanov J, Waeber C, Gertz K, Gietz A, Winter B, Bruck W, Dirnagl U, Veh RW, Endres M (2003) Selective neuronal vulnerability following mild focal brain ischemia in the mouse. Brain Pathol 13:452-64
16. Klein JP, Khera DS, Nersesyan H, Kimchi EY, Waxman SG, Blumenfeld H (2004) Dysregulation of sodium channel expression in cortical neurons in a rodent model of absence epilepsy. Brain Res 1000:102-9
17. Ketelaars SO, Gorter JA, van Vliet EA, Lopes da Silva FH, Wadman WJ (2001) Sodium currents in isolated rat CA1 pyramidal and dentate granule neurones in the poststatus epilepticus model of epilepsy. Neuroscience 105:109-20
18. Lodder J, vRaak L, Hilton A, Hardy E, Kessels A (2005) Diazepam to improve acute stroke outcome; results of the EGASIS trial (Early GABA-ergic Activation Study In Stroke): a randomised, double-blind, placebo-controlled trial. Eur Stroke Conf. retrieved 10/5/06 at: http://www.esc-bologna.org/ bologna_asp/bo_S28_oral.asp
19. Mantegazza M, Gambardella A, Rusconi R, Schiavon E, Annesi F, Cassulini RR, Labate A, Carrideo S, Chifari R, Canevini MP, Canger R, Franceschetti S, Annesi G, Wanke E, Quattrone A (2005) Identification of an Nav1 1 sodium channel (SCN1A) loss-of-function mutation associated with familial simple febrile seizures. Proc Natl Acad Sci USA 102:18177-82
20. + channel gating between fast-spiking and principal neurones of rat hippocampus. J Physiol 505:593-603
21. + channels of fast-spiking interneurons and pyramidal neurons of rat hippocampus. J Neurosci 18:8111-25
22. + conductance and the threshold for repetitive neuronal firing. Brain Res 597:92-8
23. Miles R (2002) Diversity in interneurons. Science 287:244-6
24. 2+-binding protein parvalbumin. Neurosci Lett 105:263-8
25. Nyíri G, Stephenson FA, Freund TF, Somogyi P (2003) Large variability in synaptic N-methyl-D-aspartate receptor density on interneurons and a comparison with pyramidal cell spines in the rat hippocampus. Neuroscience 119:347-63
26. Rhodes TH, Vanoye CG, Ohmori I, Ogiwara I, Yamakawa K, George AL (2005) Sodium channel dysfunction in intractable childhood epilepsy with generalized tonicclonic seizures. J Physiol 569:433-45
27. Rothman SM, Olney JW (1986) Glutamate and the pathophysiology of hypoxic-ischemic brain damage. Ann Neurol 19:105-11
28. Schwartz-Bloom RD, Sah R (2001) Aminobutyric acidA neurotransmission and cerebral ischemia. J Neurochem 77:353-71
29. Siegelin MD, Kossatz LS, Winckler J, Rami A (2005) Regulation of XIAP and Smac/DIABLO in the rat hippocampus following transient forebrain ischemia. Neurochem Int 46:41-51
30. Sugawara T, Fujimura M, Morita-Fujimura Y, Kawase M, Chan PH (1999) Mitochondrial release of cytochrome c corresponds to the selective vulnerability of hippocampal CA1 neurons in rats after transient global cerebral ischemia. J Neurosci 19:RC39 (1-6)
31. WAF1/Cip1 and PAG608/Wig-1 in ischemic preconditioning. Mol Brain Res 70:304-13
32. Wang JH (2003) Short-term cerebral ischemia causes the dysfunction of interneurons and more excitation of pyramidal neurons in rats. Brain Res Bull 60:53-8
33. 2+ permeable AMPA or kainite receptors: possible key factors in selective neurodegeneration. Trends Neurosci 23:365-71
34. Woodson W, Nitecka L, Ben-Ari Y (1989) Organization of the GABAergic system in the rat hippocampal formation: a quantitative immunocutochemical study. J Comp Neurol 280:254-71
35. v1.1 α-subunit following focal ischemic brain injury in rats: in situ hybridization and immunohistochemical analysis. Life Sci 77:1116-29
36. Yu FH, Mantegazza M, Westenbroek RE, Robbins CA, Kalume F, Burton KA, Spain WJ, McKnight GS, Scheuer T, Catterall WA (2006) Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy. Nat Neurosci 9:1142-9
37. Zhan RZ, Nadler JV, Schwartz-Bloom RD (2006) Depressed responses to applied and synaptically-released GABA in CA1 pyramidal cells, but not in CA1 interneurons, after transient forebrain ischemia. J Cereb Blood Flow Metab 26:112-24
38. Zhan RZ, Wu C, Fujihara H, Taga K, Qi S, Naito M, Shimoji K (2001) Both caspase-dependent and caspase-independent pathways may be involved in hippocampal CA1 neuronal death because of loss of cytochrome c from mitochondria in a rat forebrain ischemia model. J Cereb Blood Flow Metab 21:529-40
39. Zhao H, Yenari MA, Cheng D, Sapolsky RM, Steinberg GK (2005) Biphasic cytochrome c release after transient global ischemia and its inhibition by hypothermia. J Cereb Blood Flow Metab 25:1119-29