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Volumn 126, Issue 1, 2004, Pages 31-44

Activation of voltage-sensitive sodium channels during oxygen deprivation leads to apoptotic neuronal death

Author keywords

apoptosis; caspases; cortical neurons; hypoxia; PBS; phosphate buffered saline; sodium channels; terminal UDP nick end labeling; tetrodotoxin; TTX; TUNEL; voltage sensitive sodium channels; VSSCs

Indexed keywords

BRAIN ENZYME; CASPASE 3; LIPOCORTIN 5; SODIUM CHANNEL BLOCKING AGENT; SODIUM CHANNEL STIMULATING AGENT; TETRODOTOXIN; VERATRIDINE; VOLTAGE GATED SODIUM CHANNEL;

EID: 2342596450     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(03)00425-1     Document Type: Article
Times cited : (82)

References (84)
  • 1
    • 0033982662 scopus 로고    scopus 로고
    • Elevated levels of Ca(II) modulate the activity and inhibition of serine proteases: Implication in the mechanism of apoptosis
    • Adebodun F., Scott C.E., Cunningham C., Bustamante P.M., Bradshaw A., Ping L., Williams K.R. Elevated levels of Ca(II) modulate the activity and inhibition of serine proteases implication in the mechanism of apoptosis. Cell Biochem Funct. 18:2000;59-66
    • (2000) Cell Biochem Funct , vol.18 , pp. 59-66
    • Adebodun, F.1    Scott, C.E.2    Cunningham, C.3    Bustamante, P.M.4    Bradshaw, A.5    Ping, L.6    Williams, K.R.7
  • 2
    • 0028793257 scopus 로고
    • Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function
    • Ankarcrona M., Dypbukt J.M., Bonfoco E., Zhivotovsky B., Orrenius S., Lipton S.A., Nicotera P. Glutamate-induced neuronal death a succession of necrosis or apoptosis depending on mitochondrial function. Neuron. 15:1995;961-973
    • (1995) Neuron , vol.15 , pp. 961-973
    • Ankarcrona, M.1    Dypbukt, J.M.2    Bonfoco, E.3    Zhivotovsky, B.4    Orrenius, S.5    Lipton, S.A.6    Nicotera, P.7
  • 5
    • 0032861770 scopus 로고    scopus 로고
    • Bcl-2 prolongs neuronal survival during hypoxia-induced apoptosis
    • Banasiak K.J., Cronin T., Haddad G.G. bcl-2 prolongs neuronal survival during hypoxia-induced apoptosis. Mol Brain Res. 72:1999;214-225
    • (1999) Mol Brain Res , vol.72 , pp. 214-225
    • Banasiak, K.J.1    Cronin, T.2    Haddad, G.G.3
  • 6
    • 0032578028 scopus 로고    scopus 로고
    • Hypoxia-induced apoptosis: Effect of hypoxic severity and role of p53 in neuronal cell death
    • Banasiak K.J., Haddad G.G. Hypoxia-induced apoptosis effect of hypoxic severity and role of p53 in neuronal cell death. Brain Res. 797:1998;295-304
    • (1998) Brain Res , vol.797 , pp. 295-304
    • Banasiak, K.J.1    Haddad, G.G.2
  • 8
    • 0033618445 scopus 로고    scopus 로고
    • Caspase independent/dependent regulation of K(+), cell shrinkage, and mitochondrial membrane potential during lymphocyte apoptosis
    • Bortner C.D., Cidlowski J.A. Caspase independent/dependent regulation of K(+), cell shrinkage, and mitochondrial membrane potential during lymphocyte apoptosis. J Biol Chem. 274:1999;21953-21962
    • (1999) J Biol Chem , vol.274 , pp. 21953-21962
    • Bortner, C.D.1    Cidlowski, J.A.2
  • 9
    • 0028868824 scopus 로고
    • Serum-free B27/neurobasal medium supports differentiated growth of neurons from the striatum, substantia nigra, septum, cerebral cortex, cerebellum, and dentate gyrus
    • Brewer G.J. Serum-free B27/neurobasal medium supports differentiated growth of neurons from the striatum, substantia nigra, septum, cerebral cortex, cerebellum, and dentate gyrus. J Neurosci Res. 42:1995;674-683
    • (1995) J Neurosci Res , vol.42 , pp. 674-683
    • Brewer, G.J.1
  • 12
    • 0026497926 scopus 로고
    • Excitotoxic cell death
    • Choi D.W. Excitotoxic cell death. J Neurobiol. 23:1992;1261-1276
    • (1992) J Neurobiol , vol.23 , pp. 1261-1276
    • Choi, D.W.1
  • 13
    • 0028799654 scopus 로고
    • Calcium: Still center-stage in hypoxic-ischemic neuronal death
    • Choi D.W. Calcium still center-stage in hypoxic-ischemic neuronal death. Trends Neurosci. 18:1995;58-60
    • (1995) Trends Neurosci , vol.18 , pp. 58-60
    • Choi, D.W.1
  • 15
    • 0032168898 scopus 로고    scopus 로고
    • Regulation of class I MHC gene expression in the developing and mature CNS by neural activity
    • Corriveau R.A., Huh G.S., Shatz C.J. Regulation of class I MHC gene expression in the developing and mature CNS by neural activity. Neuron. 21:1998;505-520
    • (1998) Neuron , vol.21 , pp. 505-520
    • Corriveau, R.A.1    Huh, G.S.2    Shatz, C.J.3
  • 16
    • 0029887551 scopus 로고    scopus 로고
    • Activation of voltage-dependent sodium channels in cultured cerebellar granule cells induces neurotoxicity that is not mediated by glutamate release
    • Dargent B., Arsac C., Tricaud N., Courad F. Activation of voltage-dependent sodium channels in cultured cerebellar granule cells induces neurotoxicity that is not mediated by glutamate release. Neuroscience. 73:1996;209-216
    • (1996) Neuroscience , vol.73 , pp. 209-216
    • Dargent, B.1    Arsac, C.2    Tricaud, N.3    Courad, F.4
  • 18
    • 0026695250 scopus 로고
    • Comparative responses of brain stem and hippocampal neurons to O2 deprivation: In vitro intracellular studies
    • Donnelly D.F., Jiang C., Haddad G.G. Comparative responses of brain stem and hippocampal neurons to O2 deprivation in vitro intracellular studies. Am J Physiol. 262:1992;L549-L554
    • (1992) Am J Physiol , vol.262 , pp. 549-L554
    • Donnelly, D.F.1    Jiang, C.2    Haddad, G.G.3
  • 19
    • 0027968663 scopus 로고
    • Roles of calmodulin-dependent protein kinases and phosphatase in calcium-dependent transcription of immediate early genes
    • Enslen H., Soderling T.R. Roles of calmodulin-dependent protein kinases and phosphatase in calcium-dependent transcription of immediate early genes. J Biol Chem. 269:1994;20872-20877
    • (1994) J Biol Chem , vol.269 , pp. 20872-20877
    • Enslen, H.1    Soderling, T.R.2
  • 20
    • 0033593230 scopus 로고    scopus 로고
    • Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL
    • Finucane D.M., Bossy-Wetzel E., Waterhouse N.J., Cotter T.G., Green D.R. Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL. J Biol Chem. 274:1999;2225-2233
    • (1999) J Biol Chem , vol.274 , pp. 2225-2233
    • Finucane, D.M.1    Bossy-Wetzel, E.2    Waterhouse, N.J.3    Cotter, T.G.4    Green, D.R.5
  • 22
    • 0028080089 scopus 로고
    • Anoxia induces an increase in intracellular sodium in rat central neurons in vitro
    • Friedman J.E., Haddad G.G. Anoxia induces an increase in intracellular sodium in rat central neurons in vitro. Brain Res. 663:1994;329-334
    • (1994) Brain Res , vol.663 , pp. 329-334
    • Friedman, J.E.1    Haddad, G.G.2
  • 23
    • 0028220530 scopus 로고
    • Removal of extracellular sodium prevents anoxia-induced injury in freshly dissociated rat CA1 hippocampal neurons
    • Friedman J.E., Haddad G.G. Removal of extracellular sodium prevents anoxia-induced injury in freshly dissociated rat CA1 hippocampal neurons. Brain Res. 641:1994;57-64
    • (1994) Brain Res , vol.641 , pp. 57-64
    • Friedman, J.E.1    Haddad, G.G.2
  • 24
    • 0032828805 scopus 로고    scopus 로고
    • Sodium homeostasis in rat hippocampal slices during oxygen and glucose deprivation: Role of voltage-sensitive sodium channels
    • Fung M.L., Croning M.D., Haddad G.G. Sodium homeostasis in rat hippocampal slices during oxygen and glucose deprivation role of voltage-sensitive sodium channels. Neurosci Lett. 275:1999;41-44
    • (1999) Neurosci Lett , vol.275 , pp. 41-44
    • Fung, M.L.1    Croning, M.D.2    Haddad, G.G.3
  • 27
    • 0032528118 scopus 로고    scopus 로고
    • Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis
    • Gross A., Jockel J., Wei M.C., Korsmeyer S.J. Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis. EMBO J. 17:1998;3878-3885
    • (1998) EMBO J , vol.17 , pp. 3878-3885
    • Gross, A.1    Jockel, J.2    Wei, M.C.3    Korsmeyer, S.J.4
  • 28
    • 0031806464 scopus 로고    scopus 로고
    • The temporal profile and morphologic features of neuronal death in human stroke resemble those observed in experimental forebrain ischemia: The potential role of apoptosis
    • Guglielmo M.A., Chan P.T., Cortez S., Stopa E.G., McMillan P., Johanson C.E., Epstein M., Doberstein C.E. The temporal profile and morphologic features of neuronal death in human stroke resemble those observed in experimental forebrain ischemia the potential role of apoptosis. Neurol Res. 20:1998;283-296
    • (1998) Neurol Res , vol.20 , pp. 283-296
    • Guglielmo, M.A.1    Chan, P.T.2    Cortez, S.3    Stopa, E.G.4    McMillan, P.5    Johanson, C.E.6    Epstein, M.7    Doberstein, C.E.8
  • 29
    • 0027454115 scopus 로고
    • Mechanisms of anoxia-induced depolarization in brainstem neurons: In vitro current and voltage clamp studies in the adult rat
    • Haddad G.G., Jiang C. Mechanisms of anoxia-induced depolarization in brainstem neurons: in vitro current and voltage clamp studies in the adult rat. Brain Res. 625:1993;261-268
    • (1993) Brain Res , vol.625 , pp. 261-268
    • Haddad, G.G.1    Jiang, C.2
  • 30
    • 0027340070 scopus 로고
    • O2 deprivation in the central nervous system: On mechanisms of neuronal response, differential sensitivity and injury
    • Haddad G.G., Jiang C. O2 deprivation in the central nervous system: on mechanisms of neuronal response, differential sensitivity and injury. Progr Neurobiol. 40:1993;277-318
    • (1993) Progr Neurobiol , vol.40 , pp. 277-318
    • Haddad, G.G.1    Jiang, C.2
  • 31
    • 0021981842 scopus 로고
    • Effect of anoxia on ion distribution in the brain
    • Hansen A.J. Effect of anoxia on ion distribution in the brain. Physiol Rev. 65:1985;101-148
    • (1985) Physiol Rev , vol.65 , pp. 101-148
    • Hansen, A.J.1
  • 33
    • 0034697363 scopus 로고    scopus 로고
    • Lead and calcium produce rod photoreceptor cell apoptosis by opening the mitochondrial permeability transition pore
    • He L., Poblenz A.T., Medrano C.J., Fox D.A. Lead and calcium produce rod photoreceptor cell apoptosis by opening the mitochondrial permeability transition pore. J Biol Chem. 275:2000;12175-12184
    • (2000) J Biol Chem , vol.275 , pp. 12175-12184
    • He, L.1    Poblenz, A.T.2    Medrano, C.J.3    Fox, D.A.4
  • 35
    • 0345240928 scopus 로고    scopus 로고
    • Potassium is a critical regulator of apoptotic enzymes in vitro and in vivo
    • Hughes F.M. Jr, Cidlowski J.A. Potassium is a critical regulator of apoptotic enzymes in vitro and in vivo. Adv Enzyme Regul. 39:1999;157-171
    • (1999) Adv Enzyme Regul , vol.39 , pp. 157-171
    • Hughes Jr., F.M.1    Cidlowski, J.A.2
  • 36
    • 0026357801 scopus 로고
    • 2 tension in adult and neonatal brain slices under several experimental conditions
    • 2 tension in adult and neonatal brain slices under several experimental conditions. Brain Res. 568:1991;159-164
    • (1991) Brain Res , vol.568 , pp. 159-164
    • Jiang, C.1    Agulian, S.2    Haddad, G.G.3
  • 37
    • 0026550108 scopus 로고
    • + homeostasis during anoxia in rat hypoglossal neurons: Intracellular and extracellular in vitro studies
    • + homeostasis during anoxia in rat hypoglossal neurons intracellular and extracellular in vitro studies. J Physiol. 448:1992;697-708
    • (1992) J Physiol , vol.448 , pp. 697-708
    • Jiang, C.1    Agulian, S.2    Haddad, G.G.3
  • 38
    • 0025868406 scopus 로고
    • Effect of anoxia on intracellular and extracellular potassium activity in hypoglossal neurons in vitro
    • Jiang C., Haddad G.G. Effect of anoxia on intracellular and extracellular potassium activity in hypoglossal neurons in vitro. J Neurophysiol. 66:1991;103-111
    • (1991) J Neurophysiol , vol.66 , pp. 103-111
    • Jiang, C.1    Haddad, G.G.2
  • 39
    • 0027506783 scopus 로고
    • Neuronal death, cytoplasmic calcium and internucleosomal DNA fragmentation: Evidence for DNA fragments being released from cells
    • Joseph R., Li W., Han E. Neuronal death, cytoplasmic calcium and internucleosomal DNA fragmentation evidence for DNA fragments being released from cells. Mol Brain Res. 17:1993;70-76
    • (1993) Mol Brain Res , vol.17 , pp. 70-76
    • Joseph, R.1    Li, W.2    Han, E.3
  • 40
    • 0033993621 scopus 로고    scopus 로고
    • Sodium overload through voltage-dependent Na(+) channels induces necrosis and apoptosis of rat superior cervical ganglion cells in vitro
    • Koike T., Tanaka S., Oda T., Ninomiya T. Sodium overload through voltage-dependent Na(+) channels induces necrosis and apoptosis of rat superior cervical ganglion cells in vitro. Brain Res Bull. 51:2000;345-355
    • (2000) Brain Res Bull , vol.51 , pp. 345-355
    • Koike, T.1    Tanaka, S.2    Oda, T.3    Ninomiya, T.4
  • 41
    • 0027989808 scopus 로고
    • Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis
    • Koopman G., Reutelingsperger C.P., Kuijten G.A., Keehnen R.M., Pals S.T., van Oers M.H. Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood. 84:1994;1415-1420
    • (1994) Blood , vol.84 , pp. 1415-1420
    • Koopman, G.1    Reutelingsperger, C.P.2    Kuijten, G.A.3    Keehnen, R.M.4    Pals, S.T.5    Van Oers, M.H.6
  • 43
    • 0031918742 scopus 로고    scopus 로고
    • The mitochondrial death/life regulator in apoptosis and necrosis
    • Kroemer G., Dallaporta B., Resche-Rigon M. The mitochondrial death/life regulator in apoptosis and necrosis. Annu Rev Physiol. 60:1998;619-642
    • (1998) Annu Rev Physiol , vol.60 , pp. 619-642
    • Kroemer, G.1    Dallaporta, B.2    Resche-Rigon, M.3
  • 44
    • 0028905230 scopus 로고
    • Temporal profile of in situ DNA fragmentation after transient middle cerebral artery occlusion in the rat
    • Li Y., Chopp M., Jiang N., Yao F., Zaloga C. Temporal profile of in situ DNA fragmentation after transient middle cerebral artery occlusion in the rat. J Cereb Blood Flow Metab. 15:1995;389-397
    • (1995) J Cereb Blood Flow Metab , vol.15 , pp. 389-397
    • Li, Y.1    Chopp, M.2    Jiang, N.3    Yao, F.4    Zaloga, C.5
  • 45
    • 0028894725 scopus 로고
    • In situ detection of DNA fragmentation after focal cerebral ischemia in mice
    • Li Y., Chopp M., Jiang N., Zaloga C. In situ detection of DNA fragmentation after focal cerebral ischemia in mice. Mol Brain Res. 28:1995;164-168
    • (1995) Mol Brain Res , vol.28 , pp. 164-168
    • Li, Y.1    Chopp, M.2    Jiang, N.3    Zaloga, C.4
  • 46
    • 0029001888 scopus 로고
    • Induction of DNA fragmentation after 10 to 120 minutes of focal cerebral ischemia in rats
    • Li Y., Chopp M., Jiang N., Zhang Z.G., Zaloga C. Induction of DNA fragmentation after 10 to 120 minutes of focal cerebral ischemia in rats. Stroke. 26:1995;1252-1257
    • (1995) Stroke , vol.26 , pp. 1252-1257
    • Li, Y.1    Chopp, M.2    Jiang, N.3    Zhang, Z.G.4    Zaloga, C.5
  • 47
    • 0028091767 scopus 로고
    • + channel modulator and glutamate release inhibitor in cultured rat cerebellar neurons and in gerbil global brain ischemia
    • + channel modulator and glutamate release inhibitor in cultured rat cerebellar neurons and in gerbil global brain ischemia. Stroke. 25:1994;2476-2482
    • (1994) Stroke , vol.25 , pp. 2476-2482
    • Lysko, P.G.1    Webb, C.L.2    Yue, T.L.3    Gu, J.L.4    Feuerstein, G.5
  • 48
    • 0034662325 scopus 로고    scopus 로고
    • Modulation of Kv1.5 currents by Src tyrosine phosphorylation: Potential role in the differentiation of astrocytes
    • MacFarlane S.N., Sontheimer H. Modulation of Kv1.5 currents by Src tyrosine phosphorylation potential role in the differentiation of astrocytes. J Neurosci. 20:2000;5245-5253
    • (2000) J Neurosci , vol.20 , pp. 5245-5253
    • MacFarlane, S.N.1    Sontheimer, H.2
  • 50
    • 0024245456 scopus 로고
    • Calcium as a modulator of the immediate-early gene cascade in neurons
    • Morgan J.I., Curran T. Calcium as a modulator of the immediate-early gene cascade in neurons. Cell Calcium. 9:1988;303-311
    • (1988) Cell Calcium , vol.9 , pp. 303-311
    • Morgan, J.I.1    Curran, T.2
  • 51
    • 0033624616 scopus 로고    scopus 로고
    • ROMK1 (Kir1.1) causes apoptosis and chronic silencing of hippocampal neurons
    • Nadeau H., McKinney S., Anderson D.J., Lester H.A. ROMK1 (Kir1.1) causes apoptosis and chronic silencing of hippocampal neurons. J Neurophysiol. 84:2000;1062-1075
    • (2000) J Neurophysiol , vol.84 , pp. 1062-1075
    • Nadeau, H.1    McKinney, S.2    Anderson, D.J.3    Lester, H.A.4
  • 52
    • 0032513236 scopus 로고    scopus 로고
    • The binding properties and biological activities of Bcl-2 and Bax in cells exposed to apoptotic stimuli
    • Otter I., Conus S., Ravn U., Rager M., Olivier R., Monney L., Fabbro D., Borner C. The binding properties and biological activities of Bcl-2 and Bax in cells exposed to apoptotic stimuli. J Biol Chem. 273:1998;6110-6120
    • (1998) J Biol Chem , vol.273 , pp. 6110-6120
    • Otter, I.1    Conus, S.2    Ravn, U.3    Rager, M.4    Olivier, R.5    Monney, L.6    Fabbro, D.7    Borner, C.8
  • 53
    • 0029910914 scopus 로고    scopus 로고
    • Profluorescent protease substrates: Intramolecular dimers described by the exciton model
    • Packard B.Z., Toptygin D.D., Komoriya A., Brand L. Profluorescent protease substrates intramolecular dimers described by the exciton model. Proc Natl Acad Sci USA. 93:1996;11640-11645
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 11640-11645
    • Packard, B.Z.1    Toptygin, D.D.2    Komoriya, A.3    Brand, L.4
  • 54
    • 0032892149 scopus 로고    scopus 로고
    • An elevated bax/bcl-2 ratio corresponds with the onset of prostate epithelial cell apoptosis
    • Perlman H., Zhang X., Chen M.W., Walsh K., Buttyan R. An elevated bax/bcl-2 ratio corresponds with the onset of prostate epithelial cell apoptosis. Cell Death Diff. 6:1999;48-54
    • (1999) Cell Death Diff , vol.6 , pp. 48-54
    • Perlman, H.1    Zhang, X.2    Chen, M.W.3    Walsh, K.4    Buttyan, R.5
  • 55
    • 0017613512 scopus 로고
    • A simplification of the protein assay method of Lowry et al. which is more generally applicable
    • Peterson G.L. A simplification of the protein assay method of Lowry, et al. which is more generally applicable. Anal Biochem. 83:1977;346-356
    • (1977) Anal Biochem , vol.83 , pp. 346-356
    • Peterson, G.L.1
  • 58
    • 0034657662 scopus 로고    scopus 로고
    • An intramolecular interaction between Src homology 3 domain and guanylate kinase-like domain required for channel clustering by postsynaptic density-95/SAP90
    • Shin H., Hsueh Y.P., Yang F.C., Kim E., Sheng M. An intramolecular interaction between Src homology 3 domain and guanylate kinase-like domain required for channel clustering by postsynaptic density-95/SAP90. J Neurosci. 20:2000;3580-3587
    • (2000) J Neurosci , vol.20 , pp. 3580-3587
    • Shin, H.1    Hsueh, Y.P.2    Yang, F.C.3    Kim, E.4    Sheng, M.5
  • 59
    • 0033533726 scopus 로고    scopus 로고
    • Relative level of expression of Bax and Bcl-XL determines the cellular fate of apoptosis/necrosis induced by the overexpression of Bax
    • Shinoura N., Yoshida Y., Asai A., Kirino T., Hamada H. Relative level of expression of Bax and Bcl-XL determines the cellular fate of apoptosis/necrosis induced by the overexpression of Bax. Oncogene. 18:1999;5703-5713
    • (1999) Oncogene , vol.18 , pp. 5703-5713
    • Shinoura, N.1    Yoshida, Y.2    Asai, A.3    Kirino, T.4    Hamada, H.5
  • 60
    • 0019842691 scopus 로고
    • Cell damage in the brain: A speculative synthesis
    • Siesjo B.K. Cell damage in the brain a speculative synthesis. J Cereb Blood Flow Metab. 1:1981;155-185
    • (1981) J Cereb Blood Flow Metab , vol.1 , pp. 155-185
    • Siesjo, B.K.1
  • 61
    • 0026777223 scopus 로고
    • Pathophysiology and treatment of focal cerebral ischemia: Part I. Pathophysiology
    • Siesjo B.K. Pathophysiology and treatment of focal cerebral ischemia Part I. Pathophysiology. J Neurosurg. 77:1992;169-184
    • (1992) J Neurosurg , vol.77 , pp. 169-184
    • Siesjo, B.K.1
  • 62
    • 0026782517 scopus 로고
    • Pathophysiology and treatment of focal cerebral ischemia: Part II. Mechanisms of damage and treatment
    • Siesjo B.K. Pathophysiology and treatment of focal cerebral ischemia Part II. Mechanisms of damage and treatment. J Neurosurg. 77:1992;337-354
    • (1992) J Neurosurg , vol.77 , pp. 337-354
    • Siesjo, B.K.1
  • 63
    • 0030044586 scopus 로고    scopus 로고
    • Mechanisms of cerebral ischemia: Intracellular cascades and therapeutic interventions
    • Small D.L., Buchan A.M. Mechanisms of cerebral ischemia intracellular cascades and therapeutic interventions. J Cardiothoracic Vasc Anesth. 10:1996;139-146
    • (1996) J Cardiothoracic Vasc Anesth , vol.10 , pp. 139-146
    • Small, D.L.1    Buchan, A.M.2
  • 64
    • 0032541410 scopus 로고    scopus 로고
    • Constitutive activation of delayed-rectifier potassium channels by a src family tyrosine kinase in Schwann cells
    • Sobko A., Peretz A., Attali B. Constitutive activation of delayed-rectifier potassium channels by a src family tyrosine kinase in Schwann cells. EMBO J. 17:1998;4723-4734
    • (1998) EMBO J , vol.17 , pp. 4723-4734
    • Sobko, A.1    Peretz, A.2    Attali, B.3
  • 65
    • 0030966265 scopus 로고    scopus 로고
    • Mechanisms of calcium and sodium fluxes in anoxic myelinated central nervous system axons
    • Stys P.K., Lopachin R.M. Mechanisms of calcium and sodium fluxes in anoxic myelinated central nervous system axons. Neuroscience. 82:1998;21-32
    • (1998) Neuroscience , vol.82 , pp. 21-32
    • Stys, P.K.1    Lopachin, R.M.2
  • 68
    • 0028175464 scopus 로고
    • 2+ ionophore-induced apoptosis on cultured embryonic rat cortical neurons
    • 2+ ionophore-induced apoptosis on cultured embryonic rat cortical neurons. Brain Res. 652:1994;65-70
    • (1994) Brain Res , vol.652 , pp. 65-70
    • Takei, N.1    Endo, Y.2
  • 69
    • 0031666555 scopus 로고    scopus 로고
    • Involvement of Bcl-2 family and caspase-3-like protease in NO-mediated neuronal apoptosis
    • Tamatani M., Ogawa S., Niitsu Y., Tohyama M. Involvement of Bcl-2 family and caspase-3-like protease in NO-mediated neuronal apoptosis. J Neurochem. 71:1998;1588-1596
    • (1998) J Neurochem , vol.71 , pp. 1588-1596
    • Tamatani, M.1    Ogawa, S.2    Niitsu, Y.3    Tohyama, M.4
  • 70
    • 0031762512 scopus 로고    scopus 로고
    • Growth factors prevent changes in Bcl-2 and Bax expression and neuronal apoptosis induced by nitric oxide
    • Tamatani M., Ogawa S., Nunez G., Tohyama M. Growth factors prevent changes in Bcl-2 and Bax expression and neuronal apoptosis induced by nitric oxide. Cell Death Diff. 5:1998;911-919
    • (1998) Cell Death Diff , vol.5 , pp. 911-919
    • Tamatani, M.1    Ogawa, S.2    Nunez, G.3    Tohyama, M.4
  • 72
    • 0031972678 scopus 로고    scopus 로고
    • Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons
    • Watson A., Eilers A., Lallemand D., Kyriakis J., Rubin L.L., Ham J. Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons. J Neurosci. 18:1998;751-762
    • (1998) J Neurosci , vol.18 , pp. 751-762
    • Watson, A.1    Eilers, A.2    Lallemand, D.3    Kyriakis, J.4    Rubin, L.L.5    Ham, J.6
  • 74
    • 0033121315 scopus 로고    scopus 로고
    • Bcl-Xl- and Bax-alpha-mediated regulation of apoptosis of human neutrophils via caspase-3
    • Weinmann P., Gaehtgens P., Walzog B. Bcl-Xl- and Bax-alpha-mediated regulation of apoptosis of human neutrophils via caspase-3. Blood. 93:1999;3106-3115
    • (1999) Blood , vol.93 , pp. 3106-3115
    • Weinmann, P.1    Gaehtgens, P.2    Walzog, B.3
  • 75
    • 0034646601 scopus 로고    scopus 로고
    • Characterization of calcium release-activated apoptosis of LNCaP prostate cancer cells
    • Wertz I.E., Dixit V.M. Characterization of calcium release-activated apoptosis of LNCaP prostate cancer cells. J Biol Chem. 275:2000;11470-11477
    • (2000) J Biol Chem , vol.275 , pp. 11470-11477
    • Wertz, I.E.1    Dixit, V.M.2
  • 77
    • 0037083303 scopus 로고    scopus 로고
    • Ionic mechanism of ouabain-induced concurrent apoptosis and necrosis in individual cultured cortical neurons
    • Xiao A.Y., Wei L., Xia S., Rothman S., Yu S.P. Ionic mechanism of ouabain-induced concurrent apoptosis and necrosis in individual cultured cortical neurons. J Neurosci. 22:2002;1350-1362
    • (2002) J Neurosci , vol.22 , pp. 1350-1362
    • Xiao, A.Y.1    Wei, L.2    Xia, S.3    Rothman, S.4    Yu, S.P.5
  • 79
    • 0025966522 scopus 로고
    • The possible involvement of tetrodotoxin-sensitive ion channels in ischemic neuronal damage in the rat hippocampus
    • Yamasaki Y., Kogure K., Hara H., Ban H., Akaike N. The possible involvement of tetrodotoxin-sensitive ion channels in ischemic neuronal damage in the rat hippocampus. Neurosci Lett. 121:1991;251-254
    • (1991) Neurosci Lett , vol.121 , pp. 251-254
    • Yamasaki, Y.1    Kogure, K.2    Hara, H.3    Ban, H.4    Akaike, N.5
  • 83
    • 0031436251 scopus 로고    scopus 로고
    • Heterodimerization-independent functions of cell death regulatory proteins Bax and Bcl-2 in yeast and mammalian cells
    • Zha H., Reed J.C. Heterodimerization-independent functions of cell death regulatory proteins Bax and Bcl-2 in yeast and mammalian cells. J Biol Chem. 272:1997;31482-31488
    • (1997) J Biol Chem , vol.272 , pp. 31482-31488
    • Zha, H.1    Reed, J.C.2


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