Composition of a chemopreventive proanthocyanidin-rich fraction from cranberry fruits responsible for the inhibition of 12-O-tetradecanoyl phorbol-13-acetate (TPA)-induced ornithine decarboxylase (ODC) activity

Journal of Agricultural and Food Chemistry

Volumn 50, Issue 5, 2002, Pages 1063-1069

  Kandil, Fayez E ^a   Smith, Mary Ann L ^a   Rogers, Randy B ^a   Pépin, Marie France ^a   Song, Lynda L ^b   Pezzuto, John M ^b   Seigler, David S ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Anticarcinogenic activity; Antioxidants; Catechin; Condensed tannins; Cranberry; Epicatechin; FRAP assay; ODC assay; Proanthocyanidins; Vaccinium macrocarpon Ait

Indexed keywords

ALKALOID; ANTHOCYANIN; ANTI INFECTIVE AGENTS; ANTIINFECTIVE AGENT; ANTIOXIDANT; CATECHIN; EPICATECHIN; EPIGALLOCATECHIN; FLAVONE DERIVATIVE; FLAVONOID; GALLOCATECHIN; MYRICETIN; ORNITHINE DECARBOXYLASE; PHORBOL 13 ACETATE 12 MYRISTATE; PLANT EXTRACT; PROANTHOCYANIDIN; QUERCETIN;

ANIMAL; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL LINE; CHEMISTRY; CHEMOPROPHYLAXIS; CHROMATOGRAPHY; CRANBERRY; DIMERIZATION; ENZYME ACTIVITY; ENZYMOLOGY; EPIDERMIS; FRACTIONATION; HYDROPHILICITY; METABOLISM; MOUSE; DRUG ANTAGONISM; ISOLATION AND PURIFICATION;

ANIMALIA; VACCINIUM; VACCINIUM MACROCARPON;

ANIMALS; ANTHOCYANINS; ANTI-INFECTIVE AGENTS; ANTIOXIDANTS; CELL LINE; DIMERIZATION; EPIDERMIS; FLAVONOIDS; MICE; ORNITHINE DECARBOXYLASE; PLANT EXTRACTS; PROANTHOCYANIDINS; TETRADECANOYLPHORBOL ACETATE; VACCINIUM MACROCARPON;

EID: 0037180966     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf011136z     Document Type: Article

References (38)

1. Cranberry anthocyanins
2. Flavonol glycosides in cranberries
3. The phytochemistry of proanthocyanidin polymers
4. Detection of enocyanin in cranberry juice cocktail by HPLC anthocyanin profile
5. Long-term investigation with regard to the constituents of various cranberry varieties (Vaccinium macrocarpon Ait.)
6. The carotenoids of several low-carotenoid fruits
7. Content of the flavonols quercetin, myricetin, and kaempferol in 25 edible berries
8. Condensed tannins
9. Isolation of oligomeric proanthocyanidins from flavonoid-producing cell cultures
10. High-performance liquid chromatography/mass spectrometry analysis of proanthocyanidins in foods and beverages
11. A-type proanthocyanidin trimers from cranberry that inhibit adherence of uropathogenic P-fimbriated Escherichia coli L
12. The structure of cranberry proanthocyanidins which inhibit adherence of uropathogenic P-fimbriated Escherichia coli in vitro
13. Tannins and related compounds. LX. Isolation and characterization of proanthocyandins with a doubly-linked unit from Vaccinium vitis-idaea L
14. The impact of plant flavonoids on mammalian biology: Implications for immunity, inflammation and cancer
15. Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion and ornithin decarboxylase activity by quercetin - Possible involvement of lipoxygenase inhibition
16. Condensed vegetable tannins: Bioactivity in structure and biological activities
17. Anti-tumor-promoting activity of oligomeric proanthocyanidins in mouse epidermis in vivo
18. Identification of the major antioxidative metabolites in biological fluids of the rat with ingested (+)-catechin and (-)-epicatechin
19. Anti-tumor-promoting activity of a polyphenolic fraction isolated from grape seeds in the mouse skin two-stage initiation-promotion protocol and identification of procyanidin B5-3′-gallate as the most effective antioxidant constitutent
20. Flavonoids and tannins: Plant-based antioxidants with vitamin character
21. Plant polyphenols: Biologically active compounds or non-selective binders to protein?
22. Variability in dietary antioxidant-related natural product supplements: The need for methods of standardization
23. Inhibition of the adherence of P-fimbriated Escherichia coli to uroepithelial-cell surfaces by proanthocyanidin extracts from cranberries
24. Cranberry juice and urinary-tract health: Science supports folklore
25. In vitro anticancer activity of fruit extracts from Vaccinium species
26. Evaluation of the potential of cancer chemopreventive activity mediated by inhibition of 12-O-tetradecanoyl phorbol 13-acetate-induced ornithine decarboxylase activity
27. Ferric reducing/antioxidant power assay: Direct measure of total antioxidant activity of biological fluids and modified version for simultaneous measurement of total antioxidant power and ascorbic acid concentration
28. Genetic evidence that a phorbol ester tumor promoter stimulates ornithine decarboxylase activity by a pathway that is independent of cyclic AMP-dependent protein kinases in CHO cells
29. Rotenoids mediate potent chemopreventive activity through transcriptional regulation of ornithine decarboxylase
30. Lowry determination of protein in the presence of sulfhydryl compounds or other reducing agents
31. Antioxidant activity of berry phenolics on human low-density lipoprotein and liposome oxidation
32. Separation of the components in black tea infusion by chromatography on Toyopearl
33. Separation of malt and hop proanthocyanidins on Fractogel TSK HW-40 (S)
34. Characterization of oligomeric and polymeric procyanidins from grape seeds by liquid secondary ion mass spectrometry
35. Continuous cell culture and product recovery from wild Vaccinium pahalae germplasm