Structure of electron transfer flavoprotein-ubiquinone oxidoreductase and electron transfer to the mitochondrial ubiquinone pool

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 44, 2006, Pages 16212-16217

  Zhang, Jian ^a   Frerman, Frank E ^b   Kim, Jung Ja P ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

Acyl CoA dehydrogenases; Fatty acid oxidation; Iron sulfur flavoprotein; Membrane protein; Mitochondrial respiratory chain

Indexed keywords

ACYL COENZYME A DEHYDROGENASE; AMINO ACID; ELECTRON TRANSFERRING FLAVOPROTEIN; ELECTRON TRANSFERRING FLAVOPROTEIN DEHYDROGENASE; FLAVINE ADENINE NUCLEOTIDE; MEMBRANE PROTEIN; OXIDOREDUCTASE; QUERCETIN; SEMIQUINONE; UBIQUINONE; UNCLASSIFIED DRUG;

ACYL COENZYME A DEHYDROGENASE DEFICIENCY; ALPHA HELIX; ARTICLE; BETA CHAIN; BINDING SITE; CATALYSIS; ELECTRON TRANSPORT; ENZYME DEFICIENCY; FATTY ACID OXIDATION; HYDROPHOBICITY; METABOLIC DISORDER; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; OXIDATION REDUCTION POTENTIAL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; REDUCTION; RESPIRATORY CHAIN;

ANIMALS; CELL MEMBRANE; ELECTRON TRANSPORT; ELECTRON-TRANSFERRING FLAVOPROTEINS; ELECTROSTATICS; IRON; IRON-SULFUR PROTEINS; MITOCHONDRIA, LIVER; MODELS, MOLECULAR; OXIDATION-REDUCTION; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; SULFUR; SWINE; UBIQUINONE;

EID: 33750814320     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0604567103     Document Type: Article

References (55)

1. Ruzicka FJ, Beinert H (1977) J Biol Chem 252:8440-8445.
2. Kim JJ, Miura R (2004) Eur J Biochem 271:483-493.
3. Ghisla S, Thorpe C (2004) Eur J Biochem 271:494-508.
4. Lenaz G (2001) FEBS Lett 509:151-155.
5. Goodman SI, Binard RJ, Woontner MR, Frerman FE (2002) Mol Genet Metab 77:86-90.
6. Beard SE, Goodman SI, Bemelen K, Frerman FE (1995) Hum Mol Genet 4:157-161.
7. Gorelick RJ, Thorpe C (1986) Biochemistry 25:7092-7098.
8. Beckmann JD, Frerman FE (1985) Biochemistry 24:3922-3925.
9. Ramsay RR, Steenkamp DJ, Husain M (1987) Biochem J 241:883-892.
10. Sun F, Huo X, Zhai Y, Wang A, Xu J, Su D, Bartlam M, Rao Z (2005) Cell 121:1043-1057.
11. Yankovskaya V, Horsefield R, Tornroth S, Luna-Chavez C, Miyoshi H, Leger C, Byine B, Cecchini G, Iwata S (2003) Science 299:700-704.
12. Huang LS, Sun G, Cobessi D, Wang AC, Shen JT, Tung EY, Anderson VE, Berry EA (2006) J Biol Chem 281:5965-5972.
13. Iverson TM, Luna-Chavez C, Cecchini G, Rees DC (1999) Science 284:1961-1966.
14. Lancaster CR, Kroger A, Auer M, Michel H (1999) Nature 402:377-385.
15. Liu S, Neidhardt EA, Grossman TH, Ocain T, Clardy J (2000) Structure (London) 8:25-33.
16. Xia D, Yu CA, Kim H, Xia JZ, Kachurin AM, Zhang L, Yu L, Deisenhofei J (1997) Science 277:60-66.
17. Zhang Z, Huang L, Shulmeister VM, Chi YI, Kim KK, Hung LW, Crofts AR, Berry EA, Kim SH (1998) Nature 392:677-684.
18. Iwata S, Lee JW, Okada K, Lee JK, Iwata M, Rasmussen B, Link TA, Ramaswamy S, Jap BK (1998) Science 281:64-71.
19. Page CC, Moser CC, Chen X, Dutton PL (1999) Nature 402:47-52.
20. Fisher N, Rich PR (2000) J Mol Biol 296:1153-1162.
21. Goodman SI, Axtell KM, Bindoff LA, Beard SE, Gill RE, Frerman FE (1994) Eur J Biochem 219:277-286.
22. Holm L, Sander C (1993) J Mol Biol 233:123-138.
23. Dauter Z, Wilson KS, Sieker LC, Meyer J, Moulis JM (1997) Biochemistry 36:16065-16073.
24. Schreuder HA, van der Laan JM, Swarte MB, Kalk KH, Hol WG, Drenth J (1992) Proteins 14:178-190.
25. Bamford V, Dobbin PS, Richardson DJ, Hemmings AM (1999) Nat Struct Biol 6:1104-1107.
26. Taylor P, Pealing SL, Reid GA, Chapman SK, Walkinshaw MD (1999) Nat Struct Biol 6:1108-1112.
27. Leys D, Tsapin AS, Nealson KH, Meyer TE, Cusanovich MA, Van Beeumen JJ (1999) Nat Struct Biol 6:1113-1117.
28. Iverson TM, Luna-Chavez C, Schroder I, Cecchini G, Rees DC (2000) Curr Opin Struct Biol 10:448-455.
29. Karplus PA, Schulz GE (1989) J Mol Biol 210:163-180.
30. Perutz M (1993) Philos Trans R Soc London A 345:105-112.
31. Yin Y, Sampson NS, Vrielink A, Lario PI (2001) Biochemistry 40:13779-13787.
32. Stephens PJ, Jollie DR, Warshel A (1996) Chem Rev 96:2491-2514.
33. Denke E, Merbitz-Zahradnik T, Hatzfeld OM, Snyder CH, Link TA, Trumpower BL (1998) J Biol Chem 273:9085-9093.
34. Horsefield R, Yankovskaya V, Sexton G, Whittingham W, Shiomi K, Omura S, Byrne B, Cecchini G, Iwata S (2006) J Biol Chem 281:7309-7316.
35. Abramson J, Riistama S, Larsson G, Jasaitis A, Svensson-Ek M, Laakkonen L, Puustinen A, Iwata S, Wikstrom M (2000) Nat Struct Biol 7:910-917.
36. Bracey MH, Cravatt BF, Stevens RC (2004) FEBS Lett 567:159-165.
37. Nichols A (1992) GRASP (Columbia University, New York, NY).
38. Picot D, Loll PJ, Garavito RM (1994) Nature 367:243-249.
39. Wendt KU, Lenhart A, Schulz GE (1999) J Mol Biol 286:175-187.
40. Husain M, Stankovich MT, Fox BG (1984) Biochem J 219:1043-1047.
41. Frerman FE (1987) Biochim Biophys Acta 893:161-169.
42. Paulsen KE, Orville AM, Frerman FE, Lipscomb JD, Stankovich MT (1992) Biochemistry 31:11755-11761.
43. de Rege PJ, Williams SA, Therien MJ (1995) Science 269:1409-1413.
44. Simkovic M, Degala GD, Eaton SS, Frerman FE (2002) Biochem J 364:659-667.
45. Watmough NJ, Loehr JP, Drake SK, Frerman FE (1991) Biochemistry 30:1317-1323.
46. Simkovic M, Frerman FE (2004) Biochem J 378:633-640.
47. Sazanov LA, Hinchliffe P (2006) Science 311:1430-1436.
48. Arnoux P, Sabaty M, Alric J, Frangioni B, Guigliarelli B, Adriano JM, Pignol D (2003) Nat Struct Biol 10:928-934.
49. Otwinowski Z, Minor W (1997) Methods Enzymol 276:307-326.
50. Hendrickson WA (1991) Science 254:51-58.
51. McRee DE (1999) Practical Protein Crystallography (Academic, San Diego), 2nd Ed.
52. Furey W, Swaminathan S (1997) Methods Enzymol 277:590-620.
53. Roussel A, Inisan AG, Knoop-Mouthuy A, Cambillau C (1999) TURBO-FRODO (Centre National de la Recherche Scientifique/Universitite Marseille, Marseille, France).
54. Read RJ (1986) Acta Crystallogr A 42:140-149.
55. Brunger AT, Adams PD, Clore GM, DeLano WL, Gros P, Grosse-Kunstleve RW, Jiang JS, Kuszewski J, Nilges M, Pannu NS, et al. (1998) Acta Crystallogr D 54:905-921.