Xanthorrhizol inhibits 12-O-tetradecanoylphorbol-13-acetate-induced acute inflammation and two-stage mouse skin carcinogenesis by blocking the expression of ornithine decarboxylase, cyclooxygenase-2 and inducible nitric oxide synthase through mitogen-activated protein kinases and/or the nuclear factor-κB

Carcinogenesis

Volumn 28, Issue 6, 2007, Pages 1224-1231

  Chung, Won Yoon ^a   Park, Jae Hee ^a   Kim, Mi Jeong ^a   Kim, Heui Ok ^a   Hwang, Jae Kwan ^b   Lee, Sang Kook ^c   Park, Kwang Kyun ^a  

^a Yonsei University College of Dentistry   (South Korea)

^b Yonsei University   (South Korea)

^c Ewha Womans University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CURCUMA XANTHORRHIZA EXTRACT; CYCLOOXYGENASE 2; DIMETHYLBENZ[A]ANTHRACENE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE; ORNITHINE DECARBOXYLASE; PHORBOL 13 ACETATE 12 MYRISTATE; PLANT EXTRACT; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; XANTHORRHIZOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER STAGING; CONTROLLED STUDY; CURCUMA XANTHORRHIZA; DYSPLASIA; EDEMA; ENZYME ACTIVATION; FEMALE; HYPERPLASIA; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SKIN CANCER; SKIN CARCINOGENESIS; SKIN INFLAMMATION; SKIN PAPILLOMA; WESTERN BLOTTING; ZINGIBERACEAE;

ACUTE DISEASE; ANIMALS; ANTICARCINOGENIC AGENTS; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DISEASE MODELS, ANIMAL; EAR; EDEMA; FEMALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED ICR; NEOPLASM STAGING; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; ORNITHINE DECARBOXYLASE; PHENOLS; SKIN NEOPLASMS; TETRADECANOYLPHORBOL ACETATE;

EID: 34447532263     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgm005     Document Type: Article

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