Xanthorrhizol, a natural sesquiterpenoid from Curcuma xanthorrhiza, has an anti-metastatic potential in experimental mouse lung metastasis model

Biochemical and Biophysical Research Communications

Volumn 326, Issue 1, 2004, Pages 210-217

  Choi, Min Ah ^a   Kim, Seong Hwan ^a   Chung, Won Yoon ^a   Hwang, Jae Kwan ^b   Park, Kwang Kyun ^a  

^a Yonsei University   (South Korea)

^b Yonsei University College of Dentistry   (South Korea)

Author keywords

COX 2; ERK; In vivo mouse lung metastasis; MMP 9; Xanthorrhizol

Indexed keywords

ANTIMETASTATIC AGENT; CURCUMA XANTHORRHIZA EXTRACT; CYCLOOXYGENASE 2; GELATINASE B; MITOGEN ACTIVATED PROTEIN KINASE; PLANT EXTRACT; SESQUITERPENOID; UNCLASSIFIED DRUG; XANTHORRHIZOL;

ABDOMINAL MASS; ABDOMINAL TUMOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CURCUMA XANTHORRHIZA; DRUG DETERMINATION; DRUG INHIBITION; DRUG SCREENING; ENZYME PHOSPHORYLATION; EXAMINATION; HUMAN; HUMAN CELL; LUNG METASTASIS; LUNG PARENCHYMA; MALE; MEDICINAL PLANT; METASTASIS INHIBITION; MOLECULE; MOUSE; NONHUMAN; OBSERVATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; ANTINEOPLASTIC AGENTS; CURCUMA; DOSE-RESPONSE RELATIONSHIP, DRUG; LUNG NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NEOPLASMS, EXPERIMENTAL; PHENOLS; PHYTOTHERAPY; PLANT EXTRACTS; TREATMENT OUTCOME; TUMOR MARKERS, BIOLOGICAL;

CURCUMA; CURCUMA XANTHORRHIZA; XANTHORHIZA;

EID: 9644268126     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.11.020     Document Type: Article

References (48)

1. J.A. Wyke Overview-burgeoning promise in metastasis research Eur. J. Cancer 36 2000 1589 1594
2. J.A. Lawrence, and P.S. Steeg Mechanisms of tumor invasion and metastasis World J. Urol. 14 1996 124 130
3. N.J. MacDonald, and P.S. Steeg Molecular basis of tumor metastasis Cancer Surv. 16 1993 175 199
4. I.H. Song Cancer metastasis and metastasis suppressors Korean J. Gastroenterol. 43 2004 1 7
5. M. Inami, I. Kawamura, S. Tsujimoto, F. Nishigaki, S. Matsumoto, Y. Naoe, Y. Sasakawa, M. Matsuo, T. Manda, and T. Goto Effects of FK317, a novel anti-cancer agent, on survival of mice bearing B16BL6 melanoma and lewis lung carcinoma Cancer Lett. 181 2002 39 45
6. W.K. Hong, and M.B. Sporn Recent advances in chemoprevention of cancer Science 278 1997 1073 1077
7. Y.J. Surh, K.S. Chun, H.H. Cha, S.S. Han, Y.S. Keum, K.-K. Park, and S.S. Lee Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation Mutat. Res. 480-481 2001 243 268
8. M.T. Huang, Y.R. Lou, J.G. Xie, W. Ma, Y.P. Lu, and P. Yen Effect of dietary curcumin and dibenzoylmethane on formation of 7,12- dimethylbenz[a] anthracene-induced mammary tumors and lymphomas/leukemias in Sencar mice Carcinogenesis 19 1998 1697 1700
9. H.S. Samaha, G.J. Kelloff, V. Steele, C.V. Rao, and B.S. Reddy Modulation of apoptosis by sulindac, curcumin, phenylethyl-3-methylcaffeate, and 6-phenylhexyl isothiocyanate: apoptotic index as a biomarker in colon cancer chemoprevention and promotion Cancer Res. 57 1997 1301 1305
10. S.P. Verma, E. Salamone, and B. Goldin Curcumin and genistein, plant natural products, show synergistic inhibitory effects on the growth of human breast cancer MCF-7 cells induced by estrogenic pesticides Biochem. Biophys. Res. Commun. 233 1997 692 696
11. L.G. Menon, R. Kuttan, and G. Kuttan Anti-metastatic activity of curcumin and catechin Cancer Lett. 141 1999 159 165
12. B.B. Aggarwal, A. Kumar, and A.C. Bharti Anticancer potential of curcumin: preclinical and clinical studies Anticancer Res. 23 2003 363 398
13. G.R. Pillai I, A.S. Srivastava I, T.I. Hassanein, D.P. Chauhan, and E. Carrier Induction of apoptosis in human lung cancer cells by curcumin Cancer Lett. 208 2004 163 170
14. J.K. Hwang, J.S. Shim, N.I. Baek, and Y.R. Pyun Xanthorrhizol: a potential antibacterial agent from Curcuma xanthorrhiza against Streptococcus mutans Planta Med. 66 2000 196 197
15. J.K. Hwang, J.S. Shim, and Y.R. Pyun Antibacterial activity of xanthorrhizol from Curcuma xanthorrhiza against oral pathogens Fitoterapia 71 2000 321 323
16. R. Mata, E. Martinez, R. Bye, G. Morales, M.P. Singh, J.E. Janso, W.M. Maiese, and B. Timmermann Biological and mechanistic activities of xanthorrhizol and 4-(1′,5′-dimethylhex-4′-enyl)-2-methylphenol isolated from Iostephane heterophylla J. Nat. Prod. 64 2001 911 914
17. S.K. Lee, C.H. Hong, S.K. Huh, S.S. Kim, O.J. Oh, H.Y. Min, K.-K. Park, W.Y. Chung, and J.K. Hwang Suppressive effect of natural sesquiterpenoids on inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) activity in mouse macrophage cells J. Environ. Pathol. Toxicol. Oncol. 21 2002 141 148
18. S.H. Kim, K.O. Hong, W.Y. Chung, J.K. Hwang, and K.-K. Park Abrogation of cisplatin-induced hepatotoxicity in mice by xanthorrhizol is related to its effect on the regulation of gene transcription Toxicol. Appl. Pharmacol. 196 2004 346 355
19. I.J. Fidler General consideration for studies of experimental cancer metastasis Methods Cancer Res. 151 1978 399 439
20. L.G. Menon, R. Kuttan, and G. Kuttan Inhibition of lung metastasis in mice induced by B16F10 melanoma cells by polyphenolic compounds Cancer Lett. 95 1995 221 225
21. H. Itokawa, F. Hirayama, K. Funakoshi, and K. Takeya Studies on the antitumor bisabolane sesquiterpenoids isolated from Curcuma xanthorrhiza Chem. Pharm. Bull. 33 1985 3488 3492
22. S. Vimala, A.W. Norhanom, and M. Yadav Anti-tumour promoter activity in Malaysian ginger rhizobia used in traditional medicine Br. J. Cancer 80 1999 110 116
23. G. Li, T. Yang, and J. Yan Cyclooxygenase-2 increased the angiogenic and metastatic potential of tumor cells Biochem. Biophys. Res. Commun. 299 2002 886 890
24. C.J. Barnes, I.L. Cameron, W.E. Hardman, and M. Lee Non-steroidal anti-inflammatory drug effect on crypt cell proliferation and apoptosis during initiation of rat colon carcinogenesis Br. J. Cancer 77 1998 573 580
25. F.M. Giardiello, G.J. Offerhans, and R.N. DuBois The role of non-steroidal anti-inflammatory drugs in colorectal cancer prevention Eur. J. Cancer 31 1995 1071 1076
26. H. Sawaoka, S. Kawano, S. Tsuji, M. Tsujii, E.S. Gunawan, Y. Takei, K. Nagano, and M. Hori Cyclooxygenase-2 inhibitors suppress the growth of gastric cancer xenografts via induction of apoptosis in nude mice Am. J. Physiol. 274 1998 1061 1067
27. R. Ohno, K. Yoshinaga, T. Fujita, K. Hasegawa, H. Iseki, H. Tsunozaki, W. Ichikawa, Z. Nihei, and K. Sugihara Depth of invasion parallels increased cyclooxygenase-2 levels in patients with gastric carcinoma Cancer 91 2001 1876 1881
28. N. Kundu, Q. Yang, R. Dorsey, and A.M. Fulton Increased cyclooxygenase-2 (COX-2) expression and activity in a murine model of metastatic breast cancer Int. J. Cancer 93 2001 681 686
29. K. Kozaki, K. Koshikawa, Y. Tatematsu, O. Miyaishi, H. Saito, T. Hida, H. Osada, and T. Takahashi Multi-faceted analyses of a highly metastatic human lung cancer cell line NCI-H460-LNM35 suggest mimicry of inflammatory cells in metastasis Oncogene 20 2001 4228 4234
30. H. Koga, S. Sakisaka, M. Ohishi, T. Kawaguchi, E. Taniguchi, K. Sasatomi, M. Harada, T. Kusaba, M. Tanaka, R. Kimura, Y. Nakashima, O. Nakashima, M. Kojiro, T. Kurohiji, and M. Sata Expression of cyclooxygenase-2 in human hepatocellular carcinoma: relevance to tumor dedifferentiation Hepatology 29 1999 688 696
31. C.H. Liu, S.H. Chang, K. Narko, O.C. Trifan, M.T. Wu, E. Smith, C. Haudenschild, T.F. Lane, and T. Hla Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice J. Biol. Chem. 276 2001 18563 18569
32. J.L. Masferrer, K.M. Leahy, A.T. Koki, B.S. Zweifel, S.L. Settle, B.M. Woerner, D.A. Edwards, A.G. Flickinger, R.J. Moore, and K. Seibert Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors Cancer Res. 60 2000 1306 1311
33. R. Maekawa, H. Maki, T. Wada, H. Yoshida, K.N. Nishimoto, H. Okamoto, Y. Matsumoto, H. Tsuzuki, and T. Yoshioka Anti-metastatic efficacy and safety of MMI-166, a selective matrix metalloproteinase inhibitor Clin. Exp. Metastasis 18 2000 61 66
34. Y.T. Huang, J.J. Hwang, P.P. Lee, F.C. Ke, J.H. Huang, C.J. Huang, C. Kandaswami, E.J. Middleton, and M.T. Lee Effects of luteolin and quercetin, inhibitors of tyrosine kinase, on cell growth and metastasis-associated properties in A431 cells overexpressing epidermal growth factor receptor Br. J. Pharmacol. 128 1999 999 1010
35. 2 activates pro-matrix metalloproteinase-2 through receptor tyrosine kinases/phosphatidylinositol 3-kinase/NF-kB pathway J. Biol. Chem. 277 2002 30271 30282
36. H. Azuma, T. Inamoto, T. Sakamoto, S. Kiyama, T. Ubai, Y. Shinohara, K. Maemura, M. Tsuji, N. Segawa, H. Masuda, K. Takahara, Y. Katsuoka, and M. Watanabe Gamma-aminobutyric acid as a promoting factor of cancer metastasis; induction of matrix metalloproteinase production is potentially its underlying mechanism Cancer Res. 63 2003 8090 8096
37. T. Itoh, M. Tanioka, H. Matsuda, H. Nishimoto, T. Yoshioka, R. Suzuki, and M. Uehira Experimental metastasis is suppressed in MMP-9-deficient mice Clin. Exp. Metastasis 17 1999 177 181
38. T. Itoh, T. Ikeda, H. Gomi, S. Nakao, T. Suzuki, and S. Itohara Unaltered secretion of beta-amyloid precursor protein in gelatinase A (matrix metalloproteinase 2)-deficient mice J. Biol. Chem. 272 1997 22389 22392
39. L.J. Gary, and L. Razvan Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases Science 298 2002 1911 1912
40. S.S. Lakka, S.L. Jasti, A.P. Kyritsis, W.K. Yung, F. Ali-Osman, G.L. Nicolson, and J.S. Rao Regulation of MMP-9 (type IV collagenase) production and invasiveness in gliomas by the extracellular signal-regulated kinase and jun amino-terminal kinase signaling cascades Clin. Exp. Metastasis 18 2000 245 252
41. S.S. Lakka, S.L. Jasti, C. Gondi, D. Boyd, N. Chandrasekar, D.H. Dinh, W.C. Olivero, M. Gujrati, and J.S. Rao Downregulation of MMP-9 in ERK-mutated stable transfectants inhibits glioma invasion in vitro Oncogene 21 2002 5601 5608
42. B. Davidson, V. Givant-Horwitz, P. Lazarovici, B. Risberg, J.M. Nesland, C.G. Trope, E. Schaefer, and R. Reich Matrix metalloproteinases (MMP), EMMPRIN (extracellular matrix metalloproteinase inducer) and mitogen-activated protein kinases (MAPK): co-expression in metastatic serous ovarian carcinoma Clin. Exp. Metastasis 20 2003 621 631
43. H. Sheng, C.S. Williams, J. Shao, P. Liang, R.N. DuBois, and R.D. Beauchamp Induction of cyclooxygenase-2 by activated Ha-ras oncogene in Rat-1 fibroblasts and the role of mitogen-activated protein kinase pathway J. Biol. Chem. 273 1998 22120 22127
44. A. Adeyinka, Y. Nui, T. Cherlet, L. Snell, P.H. Watson, and L.C. Murphy Activated mitogen-activated protein kinase expression during human breast tumorigenesis and breast cancer progression Clin. Cancer Res. 8 2002 1747 1753
45. J. Albanell, J. Codony-Servat, F. Rojo, J.M. Del Campo, S. Sauleda, J. Anido, G. Raspall, J. Giralt, J. Rosello, R.I. Nicholson, J. Mendelsohn, and J. Baselga Activated extracellular signal-related kinases: association with epidermal growth factor receptor/transforming growth factor alpha expression in head and neck squamous carcinoma and inhibition by anti-epidermal growth factor receptor treatments Cancer Res. 61 2001 6500 6510
46. R.J. Davis Signal transduction by the JNK group of MAP Kinases Cell 103 2000 239 252
47. W. Zou, X. Liu, P. Yue, Z. Zhou, M.B. Sporn, R, Lotan, F.R. Khuri, and S.Y. Sun c-Jun NH2-termical kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3,12-dioxoleana-1,9-dien-28-oate in human lung cancer cells Cancer Res. 64 2004 7570 7578
48. H.D. Ryoo, T. Gorenc, and H. Steller Apoptotic cells can induce compensatory cell proliferation through the JNK and the wingless signaling pathways Dev. Cell 7 2004 491 501